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WO2013002750A3 - Determining tumor origin - Google Patents

Determining tumor origin Download PDF

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Publication number
WO2013002750A3
WO2013002750A3 PCT/US2011/031870 US2011031870W WO2013002750A3 WO 2013002750 A3 WO2013002750 A3 WO 2013002750A3 US 2011031870 W US2011031870 W US 2011031870W WO 2013002750 A3 WO2013002750 A3 WO 2013002750A3
Authority
WO
WIPO (PCT)
Prior art keywords
tumor origin
determining tumor
samples
ffpe
classify
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/US2011/031870
Other languages
French (fr)
Other versions
WO2013002750A2 (en
Inventor
Mark Erlander
Xiao-Jun Ma
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Biotheranostics Inc
Original Assignee
Biotheranostics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biotheranostics Inc filed Critical Biotheranostics Inc
Priority to JP2014518508A priority Critical patent/JP2014518086A/en
Priority to PCT/US2011/031870 priority patent/WO2013002750A2/en
Priority to BR112013026043A priority patent/BR112013026043A2/en
Priority to CA2864996A priority patent/CA2864996A1/en
Publication of WO2013002750A2 publication Critical patent/WO2013002750A2/en
Publication of WO2013002750A3 publication Critical patent/WO2013002750A3/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6809—Methods for determination or identification of nucleic acids involving differential detection
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/158—Expression markers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Analytical Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Immunology (AREA)
  • Genetics & Genomics (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Pathology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Hospice & Palliative Care (AREA)
  • Oncology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

The disclosure provides methods for the use of gene expression measurements to classify or identify among 54 cancer types in samples obtained from a subject in a clinical setting, such as in cases of formalin fixed, paraffin embedded (FFPE) samples.
PCT/US2011/031870 2011-06-29 2011-06-29 Determining tumor origin Ceased WO2013002750A2 (en)

Priority Applications (4)

Application Number Priority Date Filing Date Title
JP2014518508A JP2014518086A (en) 2011-06-29 2011-06-29 Determination of tumor origin
PCT/US2011/031870 WO2013002750A2 (en) 2011-06-29 2011-06-29 Determining tumor origin
BR112013026043A BR112013026043A2 (en) 2011-06-29 2011-06-29 tumor origin determination
CA2864996A CA2864996A1 (en) 2011-06-29 2011-06-29 A method of classifying a cell-containing sample as containing tumor cells or tissue

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/US2011/031870 WO2013002750A2 (en) 2011-06-29 2011-06-29 Determining tumor origin

Publications (2)

Publication Number Publication Date
WO2013002750A2 WO2013002750A2 (en) 2013-01-03
WO2013002750A3 true WO2013002750A3 (en) 2013-05-10

Family

ID=47424732

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2011/031870 Ceased WO2013002750A2 (en) 2011-06-29 2011-06-29 Determining tumor origin

Country Status (4)

Country Link
JP (1) JP2014518086A (en)
BR (1) BR112013026043A2 (en)
CA (1) CA2864996A1 (en)
WO (1) WO2013002750A2 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2006255282A1 (en) 2005-06-03 2006-12-14 Aviaradx, Inc. Identification of tumors and tissues
US20140349856A1 (en) * 2013-03-15 2014-11-27 Biotheranostics, Inc. Neuroendocrine Tumors
BR102014003033B8 (en) * 2014-02-07 2020-12-22 Fleury S/A process and classification system for tumor samples of unknown and / or uncertain origin; quality control process of biological tumor samples of known origin and quality control process of biological samples of unknown and / or uncertain origin

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20060094035A1 (en) * 2004-06-04 2006-05-04 Arcturus Bioscience, Inc. Identification of tumors
US20070020655A1 (en) * 2005-06-03 2007-01-25 Aviaradx, Inc. Identification of Tumors and Tissues
WO2007137366A1 (en) * 2006-05-31 2007-12-06 Telethon Institute For Child Health Research Diagnostic and prognostic indicators of cancer
WO2010108638A1 (en) * 2009-03-23 2010-09-30 Erasmus University Medical Center Rotterdam Tumour gene profile

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20060094035A1 (en) * 2004-06-04 2006-05-04 Arcturus Bioscience, Inc. Identification of tumors
US20070020655A1 (en) * 2005-06-03 2007-01-25 Aviaradx, Inc. Identification of Tumors and Tissues
WO2007137366A1 (en) * 2006-05-31 2007-12-06 Telethon Institute For Child Health Research Diagnostic and prognostic indicators of cancer
WO2010108638A1 (en) * 2009-03-23 2010-09-30 Erasmus University Medical Center Rotterdam Tumour gene profile

Also Published As

Publication number Publication date
JP2014518086A (en) 2014-07-28
CA2864996A1 (en) 2013-01-03
WO2013002750A2 (en) 2013-01-03
BR112013026043A2 (en) 2019-02-26

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