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WO2013040358A3 - Procede et compositions pour la détection d'agr2 - Google Patents

Procede et compositions pour la détection d'agr2 Download PDF

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Publication number
WO2013040358A3
WO2013040358A3 PCT/US2012/055416 US2012055416W WO2013040358A3 WO 2013040358 A3 WO2013040358 A3 WO 2013040358A3 US 2012055416 W US2012055416 W US 2012055416W WO 2013040358 A3 WO2013040358 A3 WO 2013040358A3
Authority
WO
WIPO (PCT)
Prior art keywords
agr2
compositions
detection
assays
cancer
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/US2012/055416
Other languages
English (en)
Other versions
WO2013040358A2 (fr
Inventor
Alvin Y. Liu
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of Washington Center for Commercialization
Original Assignee
University of Washington Center for Commercialization
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University of Washington Center for Commercialization filed Critical University of Washington Center for Commercialization
Publication of WO2013040358A2 publication Critical patent/WO2013040358A2/fr
Publication of WO2013040358A3 publication Critical patent/WO2013040358A3/fr
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
    • C07K16/3069—Reproductive system, e.g. ovaria, uterus, testes, prostate
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57407—Specifically defined cancers
    • G01N33/57434—Specifically defined cancers of prostate
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57484—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites
    • G01N33/57488—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites involving compounds identifable in body fluids

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Cell Biology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Organic Chemistry (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Analytical Chemistry (AREA)
  • Oncology (AREA)
  • Hospice & Palliative Care (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Food Science & Technology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Reproductive Health (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pregnancy & Childbirth (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Abstract

La technologie décrite ici concerne le diagnostic, le pronostic et le traitement du cancer, par exemple, du cancer de la prostate selon les procédés et les compositions destinés à la détection d'AGR2.
PCT/US2012/055416 2011-09-14 2012-09-14 Procede et compositions pour la détection d'agr2 Ceased WO2013040358A2 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201161534791P 2011-09-14 2011-09-14
US61/534,791 2011-09-14

Publications (2)

Publication Number Publication Date
WO2013040358A2 WO2013040358A2 (fr) 2013-03-21
WO2013040358A3 true WO2013040358A3 (fr) 2013-05-10

Family

ID=47883981

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2012/055416 Ceased WO2013040358A2 (fr) 2011-09-14 2012-09-14 Procede et compositions pour la détection d'agr2

Country Status (1)

Country Link
WO (1) WO2013040358A2 (fr)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN116348140A (zh) * 2020-09-30 2023-06-27 北美生物技术公司 抗腺苷受体（A2aR）抗体
US20240085427A1 (en) * 2021-01-05 2024-03-14 Musc Foundation For Research Development AN AGR2Xcd3 BISPECIFIC ENGAGER FOR THE TREATMENT OF CANCER
WO2022251403A1 (fr) * 2021-05-28 2022-12-01 Icahn School Of Medicine At Mount Sinai Anticorps anti-sars-cov-2 et leurs utilisations
CN118786140A (zh) * 2021-12-23 2024-10-15 诺瓦瓦克斯股份有限公司 抗SARS-CoV-2刺突（S）抗体及其在治疗COVID-19中的用途

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2008067065A2 (fr) * 2006-10-19 2008-06-05 Shiv Srivastava Procédés, kits et systèmes pour diagnostiquer et pronostiquer le cancer de la prostate en utilisant des biomarqueurs sécrétés
US7429382B2 (en) * 2002-10-16 2008-09-30 Corixa Corporation Antibodies that bind cell-associated CA 125/O772P and methods of use thereof
US20100062426A1 (en) * 2005-11-03 2010-03-11 O'hara Shawn Mark AGR2 and TFF3 Regulation in the Diagnosis and Treatment of Cancer
US20110052586A1 (en) * 2006-08-26 2011-03-03 The University Of Liverpool Antibodies to an epitope of agr2, assays and hybridomas

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7429382B2 (en) * 2002-10-16 2008-09-30 Corixa Corporation Antibodies that bind cell-associated CA 125/O772P and methods of use thereof
US20100062426A1 (en) * 2005-11-03 2010-03-11 O'hara Shawn Mark AGR2 and TFF3 Regulation in the Diagnosis and Treatment of Cancer
US20110052586A1 (en) * 2006-08-26 2011-03-03 The University Of Liverpool Antibodies to an epitope of agr2, assays and hybridomas
WO2008067065A2 (fr) * 2006-10-19 2008-06-05 Shiv Srivastava Procédés, kits et systèmes pour diagnostiquer et pronostiquer le cancer de la prostate en utilisant des biomarqueurs sécrétés

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
ZHANG, JIN-SAN ET AL.: "AGR2, an androgen-inducible secretory protein overexpressed in prostate cancer", GENES CHROMOSOMES & CANCER, vol. 43, no. 3, 2005, pages 249 - 259 *
ZHANG, Y. ET AL.: "Increased expression of anterior gradient-2 is significantly associated with poor survival of prostate cancer patients", PROSTATE CANCER AND PROSTATIC DISEASES, vol. 10, no. 3, 2007, pages 293 - 300, XP008090161, DOI: doi:10.1038/sj.pcan.4500960 *

Also Published As

Publication number Publication date
WO2013040358A2 (fr) 2013-03-21

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