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WO2012123879A1 - Dispositif de biopsie à cathéter à risque de contamination réduit - Google Patents

Dispositif de biopsie à cathéter à risque de contamination réduit Download PDF

Info

Publication number
WO2012123879A1
WO2012123879A1 PCT/IB2012/051142 IB2012051142W WO2012123879A1 WO 2012123879 A1 WO2012123879 A1 WO 2012123879A1 IB 2012051142 W IB2012051142 W IB 2012051142W WO 2012123879 A1 WO2012123879 A1 WO 2012123879A1
Authority
WO
WIPO (PCT)
Prior art keywords
envelope
medical examination
examination apparatus
surrounding region
pulling
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/IB2012/051142
Other languages
English (en)
Inventor
Peter Mazurkewitz
Christoph Leussler
Peter Vernickel
Oliver Lips
Sascha Krueger
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Philips Intellectual Property and Standards GmbH
Koninklijke Philips NV
Original Assignee
Philips Intellectual Property and Standards GmbH
Koninklijke Philips Electronics NV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Philips Intellectual Property and Standards GmbH, Koninklijke Philips Electronics NV filed Critical Philips Intellectual Property and Standards GmbH
Publication of WO2012123879A1 publication Critical patent/WO2012123879A1/fr
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B10/00—Instruments for taking body samples for diagnostic purposes; Other methods or instruments for diagnosis, e.g. for vaccination diagnosis, sex determination or ovulation-period determination; Throat striking implements
    • A61B10/02—Instruments for taking cell samples or for biopsy
    • A61B10/0233—Pointed or sharp biopsy instruments
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B10/00—Instruments for taking body samples for diagnostic purposes; Other methods or instruments for diagnosis, e.g. for vaccination diagnosis, sex determination or ovulation-period determination; Throat striking implements
    • A61B10/02—Instruments for taking cell samples or for biopsy
    • A61B10/06—Biopsy forceps, e.g. with cup-shaped jaws
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods
    • A61B2017/00831—Material properties
    • A61B2017/0084—Material properties low friction
    • A61B2017/00845—Material properties low friction of moving parts with respect to each other
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods
    • A61B2017/00831—Material properties
    • A61B2017/00858—Material properties high friction or non-slip
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B90/00—Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups A61B1/00 - A61B50/00, e.g. for luxation treatment or for protecting wound edges
    • A61B90/04—Protection of tissue around surgical sites against effects of non-mechanical surgery, e.g. laser surgery
    • A61B2090/0409—Specification of type of protection measures
    • A61B2090/0427—Prevention of contact

Definitions

  • the present invention relates to an envelope for covering a medical examination device, a medical examination apparatus, a system with a medical examination apparatus, a use of an envelope, and a method for retracting a device with an envelope out of a surrounding region.
  • a medical examination apparatus a medical examination apparatus
  • a system with a medical examination apparatus a use of an envelope
  • a method for retracting a device with an envelope out of a surrounding region a device with an envelope out of a surrounding region.
  • the exemplary embodiments can also find application in conjunction with other medical devices and the like.
  • Biopsy can include a medical test involving the removal of cells or tissues from a living subject for examination, for example the tissue sample is analyzed microscopically by a pathologist and/or also chemically to determine the presence or extent of a disease. Biopsies may be taken percutaneously (via a needle through the skin), transvenously (through the blood vessels), or directly during abdominal surgery.
  • an interventional device for example a needle, which has to be firstly inserted into tissue and then usually removed via the same channel.
  • healthy tissue can be contaminated by the suspicious sample of tissue while removing the device, for example.
  • an extracted device for example a catheter or a needle.
  • an envelope for covering a medical examination device has a longitudinal shape and comprises an inner surface, an outer surface, a first end, and a second end.
  • the first end and the second end are arranged opposite to each other in a longitudinal direction of the envelope, wherein the first end is attachable to a device and wherein the second end is open.
  • the envelope is arranged to upend inwards while pulling the first end towards the second end, such that at least a part of the outer surface is facing inwards.
  • the envelope is adapted to assume a first state and a second state, wherein in the first state, the outer surface is facing outwards and wherein in the second state at least a part of the outer surface is facing inwards.
  • a device provided with an envelope allows retracting of the device from a surrounding region in a way without moving the envelope at a contact surface of the envelope and the surrounding region along the retracting direction of the device.
  • a medical examination apparatus comprises a device and an envelope according to the above mentioned aspect of the invention, wherein the device is adapted to be insertable at least partly into an object and wherein the first end of the envelope is attached to the device. Thereby, the device is pullable in a first direction from the first end of the envelope to the second end of the envelope, such that at least a part of the outer surface of the envelope is facing inwards, thereby forming a receiving volume separated from the surrounding region.
  • the above and hereinafter described envelope can be a thin membrane.
  • the envelope can be made from very thin material, for example much smaller than 1 mm, thus the overall diameter of the device essentially does not increase when covered with the envelope.
  • the membrane may be at least partially permeable for a fluid or a gas.
  • the membrane may be permeable only in a bended region, for example in a curved part of the membrane while upending the membrane.
  • the envelope While the device is being retracted from a surrounding region, the envelope upends inwards and may also cover a tissue sample taken. As the outside of the envelope may also be contaminated, the risk of contaminating the surrounding region along the retracting channel is further reduced by upending inwards the envelope.
  • the device can be any medical interventional device which has to be inserted and then retracted from a surrounding region.
  • the above and hereinafter described envelope may comprise a flexible and strong material, for example latex.
  • the envelope may comprise another material, as long as this material is flexible and strong.
  • the material of the envelope should at least be that flexible that it allows the envelope upending inwards.
  • the material of the envelope may be as strong as to avoid tearing of the envelope while introducing the device with an envelope into an object, for example the body of a patient.
  • a system comprises a medical examination apparatus according to the above mentioned aspect of the invention, a locating unit, a feedback unit, and a pullback unit.
  • the locating unit is adapted to determine a position of the device
  • the feedback unit is adapted to display a position of the device
  • the pullback unit is adapted to pull the device in a direction from the first end of the envelope to the second end of the envelope, such that at least a part of the outer surface of the envelope is facing inwards.
  • the locating unit may be an X-ray detector, an ultrasound scanner or a magnetic resonance scanner, adapted to determine the position of the device of the medical examination apparatus in an object, for example the body of a patient.
  • the feedback unit may be a monitor.
  • the feedback unit may be connected to a computer.
  • the feedback unit may be adapted to display the position of the device of the medical examination apparatus in the object the device has been inserted to.
  • the pullback unit may be coupled to the device, such that the pullback unit may pull the device out of an object.
  • the pullback unit may be coupled to the device by a cord, by a cable or by other kinds of attachment.
  • a shaft may also be used for coupling the pullback unit to the device, for example.
  • an envelope according to the above mentioned example is used in order to avoid contamination along a moving path in an object while pulling out the device from the object.
  • a method for retracting a device with an envelope out of a surrounding region In a first step, an envelope with a longitudinal shape, a first end and a second end is provided, wherein the first end is attached to a device. In a second step, the device is being pulled out of the surrounding region. In a third step, the envelope is being gradually upended by pulling the first end towards the second end while retracting the device out of the surrounding region, such that a lengthwise movement between a contact region of the envelope and the surrounding region is avoided.
  • the present invention is not limited to medical devices.
  • the invention may be used in any fields where a contamination of a surrounding region along a retracting path of, for example for taking a sample, is to be avoided.
  • the gist of the invention can be seen as the gist of the invention to provide an envelope for a device, wherein a first end of the envelope is attached to a device and upends inwards while the device is being pulled from the first end towards a second end of the envelope, such that the upending envelope is forming a receiving volume to separate a sample from a surrounding region and an outer surface of the envelope, which may be contaminated, is being upended inwards and a lengthwise movement between a contact region of the envelope and a surrounding region is avoided.
  • Fig 1 illustrates a perspective view of an envelope according to an exemplary embodiment of the invention.
  • Fig. 2 illustrates a side view of an envelope according to another exemplary embodiment of the invention.
  • Fig. 3 illustrates a side view of an envelope according to another exemplary embodiment of the invention.
  • Fig. 4 illustrates an envelope according to another exemplary embodiment of the invention in a partly upended state.
  • Fig. 5 illustrates a medical examination apparatus according to an exemplary embodiment of the invention.
  • Fig. 6 illustrates a medical examination apparatus according to another exemplary embodiment of the invention.
  • Fig. 7 illustrates a medical examination apparatus according to another exemplary embodiment of the invention.
  • Fig. 8 illustrates a medical examination apparatus according to another exemplary embodiment of the invention.
  • Fig. 9 illustrates a medical examination apparatus according to another exemplary embodiment of the invention.
  • Fig. 10 illustrates a medical examination apparatus according to another exemplary embodiment of the invention.
  • Fig. 11 illustrates a medical examination apparatus according to another exemplary embodiment of the invention.
  • Fig. 12A illustrates a medical examination apparatus according to another exemplary embodiment of the invention.
  • Fig. 12B illustrates a medical examination apparatus according to another exemplary embodiment of the invention.
  • Fig. 13 illustrates a system according to an exemplary embodiment of the invention.
  • Fig. 14 illustrates a flowchart of a method according to an exemplary embodiment of the invention.
  • Fig. 1 illustrates an envelope 100 with an inner surface 101, an outer surface
  • the envelope has a longitudinal shape in the direction from the first end 103 to the second end 104.
  • the envelope 100 may be provided with the cross-section of another geometric form, for example rectangular or elliptical.
  • An envelope with a rectangular cross-section may be provided with rounded edges.
  • Fig. 2 illustrates another view of an exemplary embodiment of an envelope 100.
  • the envelope 100 has an inner surface 101, and outer surface 102, a first end 103, and second end 104.
  • the envelope 100 is depicted with a first end 103 and a second end 104 open.
  • Fig. 3 illustrates an envelope according to another exemplary embodiment of the invention.
  • the envelope 100 has an inner surface 101, an outer surface 102, a first end
  • the envelope 100 may be provided with a rounded section 105 at the first end 103.
  • the envelope 100 may also be provided with a rounded section 105 at the second end 104.
  • the first end 103 may be closed, which is illustrated with a dotted line.
  • the rounded section 105 implicates that the diameter at the first end 103 of the envelope is smaller than the diameter of the envelope in a middle section 106.
  • Fig. 1, Fig. 2, and Fig. 3 show the envelope in a first state, wherein the outer surface is facing outwards.
  • Fig. 4 illustrates the envelope according to an exemplary embodiment of the invention, wherein the envelope has assumed a second state, wherein in the second state at least a part of the outer surface 102 is facing inwards.
  • a receiving volume 402 is formed such that the receiving volume 402 is separated from the surrounding region 401 by being enclosed by the envelope 100.
  • the first end 103 may be closed or open and may be provided with rounded edges 105.
  • a first friction characteristic of the outer surface 102 may be arranged to be higher than a second friction characteristic of the inner surface 101.
  • a body or a device (not shown) may be pulled in a direction from the first end 103 towards the second end 104 and an upending may be ensured as the friction characteristic of the outer surface 102 is larger than the friction characteristic of the inner surface 101.
  • the layer friction between the envelope and the surrounding results in that the device can be pulled out without the envelope sticking to the device, but rather sticking to the surrounding.
  • the device can so to speak slide along or in relation to the inner side of the envelope.
  • Fig. 5 illustrates a medical examination apparatus 500 according to an exemplary embodiment of the invention.
  • the apparatus 500 comprises a device 501 and an envelope, for example the envelope 100 as described above and hereinafter, wherein the first end 103 of the envelope 100 is attached to the device 501.
  • the apparatus 500 may be inserted or injected in a surrounding region 401 of an object 510, such that the apparatus 500 is introduced at least partly into the object 510, wherein the outer surface 102 of the envelope 100 is touching the surrounding region 401.
  • the device 501 may be pulled in a direction 503 from the first end 103 of the envelope towards the second end 104 of the envelope. By pulling the device 501 in the direction 503, the medical examination apparatus 500 is being extracted from the body 510.
  • the device 501 as described above and hereinafter may be a medical device.
  • the object 510 may be a body region of a patient, for example a cancer tissue area.
  • Fig. 6 illustrates a further example of the medical examination apparatus 500.
  • the apparatus 500 comprises a device 501 and an envelope 100.
  • the envelope 100 is shown in a second state, wherein at least a part of the outer surface 102 is upended inwards and encloses at least a part 601 of the device 501.
  • the first end 103 of the envelope 100 may be attached to the device 501 in a front region 602, a middle region 603, or a rear region 604 of the device 501 (the latter two examples not further shown).
  • the device 501 as described above and hereinafter may be a biopsy needle.
  • the first end 103 of the envelope 100 may be attached in front portion of the biopsy needle.
  • Fig. 7 illustrates another exemplary embodiment of the invention.
  • the medical examination apparatus 500 as described above and hereinafter may comprise a catcher 701.
  • the catcher 701 may adapted to grasp a sample 702.
  • the envelope 100 is adapted to enclose the catcher 701 and the sample 702 while pulling the device in the direction 503.
  • the catcher 701 may be a medical forceps.
  • the envelope 100 encloses the catcher 701 and the sample 702, such that the sample 702 is separated by the upended envelope 100 from the surrounding region 401. Hence, the risk of contamination of the surrounding region 401 by the sample 702 may be minimized.
  • Fig. 8 illustrates an example of the medical examination apparatus 500 according to another exemplary embodiment of the invention.
  • a first substance 801 may be provided between the inner surface 101 of the envelope 100 and the device 501, adapted such that friction between the inner surface 101 of the envelope 100 and the device 501 is reduced.
  • the first substance 801 may be a fluid, a gas, or a powder.
  • the first substance 801 may be a lubricant.
  • the first substance may be provided to ensure that a second friction
  • the characteristic of the inner surface 101 and the device 501 is lower than a first friction characteristic of the outer surface 102 and a contacting surface of the surrounding region 401.
  • the first substance 801 may be provided to ensure the upending of the envelope 100 while retracting the device 501 from the surrounding region 401.
  • Fig. 9 illustrates a medical examination apparatus 500 according to another exemplary embodiment of the invention.
  • the outer surface 102 of the device 501 may comprise a layer 902, wherein the layer 902 is adapted to reduce friction between the outer surface of the device and the inner surface of the envelope.
  • the layer 902 may be used as an alternative to the first substance 801.
  • the layer 902 may also be used in conjunction, i.e. in addition with a substance such as the first substance 801.
  • the layer 902 may comprise Teflon.
  • Fig. 10 illustrates a medical examination apparatus 500 according to another exemplary embodiment of the invention.
  • the apparatus 500 may be adapted to deliver a second substance 1001 to the inner surface 101 of the envelope 100, such that the outer surface 102 of the envelope 100 may be pressed in a direction along the arrows 1002 against an abutting surface 1003 of a surrounding region 401, such that a friction between the outer surface 102 of the envelope 100 and the abutting surface 1003 is increased.
  • the first substance may also be used for this purpose, as the second substance may be used to reduce the friction between the inner surface 101 of the envelope 100 and the device 501.
  • the second end 104 of the envelope 100 as described above and hereinafter may be closable such that a pressure may be applied between the inner surface 101 and the device 501.
  • Fig. 11 illustrates a medical examination apparatus 500 according to another exemplary embodiment of the invention.
  • the apparatus 500 may comprise a drug unit 1101 to deliver drugs 1102 to at least a part of the surrounding region 401 of the first end 103 of the envelope 100.
  • the drug unit 1101 may be arranged centrically or off-center in a front portion of the device 501, wherein the front portion of the device 501 is close to the first end 103 of the envelope 100.
  • Fig. 12A illustrates a medical examination apparatus 500 according to an exemplary embodiment of the invention, wherein the envelope 100 is shown in a first state.
  • the envelope 100 may be an adaptive emitting envelope, wherein the envelope is adapted to release drugs 1102 in a bent region 1201 of the envelope 100, such that the drugs 1102 are delivered to the surrounding region 401 along the arrows 1202.
  • the drugs may be enclosed in ventricles under the outer surface of the envelope.
  • the ventricles and the envelope may be adapted to be opened in a bent region of the envelope while upending the envelope, such that the enclosed drugs are released in the bent region 1201 of the envelope 100.
  • Fig. 12B illustrates an exemplary embodiment of the medical examination apparatus 500 according to the invention, wherein the envelope 100 is shown in a second state.
  • Fig. 12B depicts that by upending the envelope 100, another region of the envelope 100 is being bent, such that other pores of the porous layer of the envelope 100 are being opened and thereby releasing drugs 1102 in the gradually moving bent region 1201 and delivering drugs along the arrows 1202 to the surrounding region 401.
  • Fig. 12B shows that by delivering drugs in a bent region of the envelope, it is possible to ensure that the opening of the surrounding region of the envelope is being delivered with drugs, such that a contamination risk is further reduced.
  • Fig. 13 illustrates a system 1300 according to an exemplary embodiment of the invention.
  • the system 1300 comprises a medical examination apparatus 500 as described above and hereinafter, a locating unit 1301, a feedback unit 1302, and a pullback unit 1303.
  • the locating unit may be adapted to determine a position of the device 501 of the medical examination apparatus 500.
  • the locating unit may be an X-ray, an ultrasonic device or a magnetic resonance scanner or another device adapted to determine a position of a device injected into an object.
  • the feedback unit may be adapted to display the position of the device.
  • the feedback unit may be a monitor or a display.
  • the feedback unit may be connected to a computer.
  • the feedback unit may be connected to the locating unit and adapted to receive information regarding to the position of the device.
  • the pullback unit may be adapted to pull the device in a direction from the first end of the envelope to the second end of the envelope, such that at least a part of the outer surface of the envelope is facing inwards.
  • the pullback unit may comprise an actuator, wherein the actuator is adapted to apply a force to the device, such that the device is retracted of a body.
  • the feedback unit may be connected to the pullback unit, such that the feedback unit controls the actuator of the pullback unit.
  • the feedback unit may be adapted to control the motion of the device by the pullback unit.
  • the pullback unit may be adapted to be controlled manually.
  • Fig. 14 depicts a flowchart of a method 1400 according to an exemplary embodiment of the invention.
  • the flowchart depicts a method for retracting a device with an envelope out of a surrounding region.
  • an envelope is provided with a longitudinal shape, the first end and a second end, wherein the first end is attached to a device.
  • a second step 1402 the device is being pulled out of the surrounding region.
  • a third step 1403 the envelope is being gradually upended during the pulling out in the second step, e.g. of the first end towards the second end while retracting the device out of the surrounding region, such that a lengthwise movement at a contact region of the envelope and a surrounding region is avoided.
  • a volume is gradually enclosed by the upended envelope.
  • a tissue sample is enclosed in the volume formed by the upended envelope.

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medical Informatics (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pathology (AREA)
  • Molecular Biology (AREA)
  • Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Apparatus For Radiation Diagnosis (AREA)

Abstract

L'invention concerne une enveloppe destinée à couvrir un dispositif. Ladite enveloppe présente une forme longitudinale et comprend une surface interne, une surface externe, une première extrémité et une seconde extrémité. La première extrémité et la seconde extrémité sont opposées l'une à l'autre dans une direction longitudinale de l'enveloppe, la première extrémité pouvant se fixer à un dispositif, la seconde extrémité étant ouverte. L'enveloppe est disposée de manière à être retournée vers l'intérieur tout en tirant la première extrémité vers la seconde extrémité, de sorte qu'au moins une partie de la surface extérieure regarde vers l'intérieur.
PCT/IB2012/051142 2011-03-17 2012-03-12 Dispositif de biopsie à cathéter à risque de contamination réduit Ceased WO2012123879A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP11158596 2011-03-17
EP11158596.4 2011-03-17

Publications (1)

Publication Number Publication Date
WO2012123879A1 true WO2012123879A1 (fr) 2012-09-20

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Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IB2012/051142 Ceased WO2012123879A1 (fr) 2011-03-17 2012-03-12 Dispositif de biopsie à cathéter à risque de contamination réduit

Country Status (1)

Country Link
WO (1) WO2012123879A1 (fr)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2013173865A1 (fr) * 2012-05-21 2013-11-28 The State Of Queensland Through The Department Of Health Appareil et procédé de prélèvement d'échantillon
WO2021029955A1 (fr) * 2019-08-12 2021-02-18 Covidien Lp Canule pour empêcher l'ensemencement tumoral

Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001000080A2 (fr) * 1999-06-29 2001-01-04 Jones Jeffrey S Manchons de securite pour endoscopes
US20050197595A1 (en) * 2004-03-05 2005-09-08 Percutaneous Systems, Inc. Non-seeding biopsy device and method
EP1772104A2 (fr) * 2005-10-07 2007-04-11 Tsion Israel Medical Systems Ltd. Dispositif de protection anti-contamination
WO2008044044A2 (fr) * 2006-10-11 2008-04-17 Imperial Innovations Limited Instruments chirurgicaux
US20080306404A1 (en) * 2006-10-10 2008-12-11 Ronald Timothy R Dual-passage biopsy needle device
US20090112119A1 (en) * 2007-10-31 2009-04-30 Kim Stanley I Rotating biopsy device and biopsy robot
WO2009153723A1 (fr) 2008-06-20 2009-12-23 Koninklijke Philips Electronics, N.V. Méthode et système permettant d'effectuer des biopsies

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001000080A2 (fr) * 1999-06-29 2001-01-04 Jones Jeffrey S Manchons de securite pour endoscopes
US20050197595A1 (en) * 2004-03-05 2005-09-08 Percutaneous Systems, Inc. Non-seeding biopsy device and method
EP1772104A2 (fr) * 2005-10-07 2007-04-11 Tsion Israel Medical Systems Ltd. Dispositif de protection anti-contamination
US20080306404A1 (en) * 2006-10-10 2008-12-11 Ronald Timothy R Dual-passage biopsy needle device
WO2008044044A2 (fr) * 2006-10-11 2008-04-17 Imperial Innovations Limited Instruments chirurgicaux
US20090112119A1 (en) * 2007-10-31 2009-04-30 Kim Stanley I Rotating biopsy device and biopsy robot
WO2009153723A1 (fr) 2008-06-20 2009-12-23 Koninklijke Philips Electronics, N.V. Méthode et système permettant d'effectuer des biopsies

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2013173865A1 (fr) * 2012-05-21 2013-11-28 The State Of Queensland Through The Department Of Health Appareil et procédé de prélèvement d'échantillon
WO2021029955A1 (fr) * 2019-08-12 2021-02-18 Covidien Lp Canule pour empêcher l'ensemencement tumoral
US12232768B2 (en) 2019-08-12 2025-02-25 Covidien Lp Cannula for preventing tumor seeding

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