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WO2012108746A3 - Composition and cosmetic composition for treating brain cancer comprising rubia cordifolia root extract - Google Patents

Composition and cosmetic composition for treating brain cancer comprising rubia cordifolia root extract Download PDF

Info

Publication number
WO2012108746A3
WO2012108746A3 PCT/KR2012/001080 KR2012001080W WO2012108746A3 WO 2012108746 A3 WO2012108746 A3 WO 2012108746A3 KR 2012001080 W KR2012001080 W KR 2012001080W WO 2012108746 A3 WO2012108746 A3 WO 2012108746A3
Authority
WO
WIPO (PCT)
Prior art keywords
composition
brain cancer
rubia cordifolia
cosmetic composition
treating brain
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/KR2012/001080
Other languages
French (fr)
Korean (ko)
Other versions
WO2012108746A2 (en
Inventor
황성연
정경채
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
KOREA BIO MEDICAL SCIENCE INSTITUTE
Original Assignee
KOREA BIO MEDICAL SCIENCE INSTITUTE
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by KOREA BIO MEDICAL SCIENCE INSTITUTE filed Critical KOREA BIO MEDICAL SCIENCE INSTITUTE
Publication of WO2012108746A2 publication Critical patent/WO2012108746A2/en
Publication of WO2012108746A3 publication Critical patent/WO2012108746A3/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/74Rubiaceae (Madder family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A61K8/9783Angiosperms [Magnoliophyta]
    • A61K8/9789Magnoliopsida [dicotyledons]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/33Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/33Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/333Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using mixed solvents, e.g. 70% EtOH
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/50Methods involving additional extraction steps
    • A61K2236/51Concentration or drying of the extract, e.g. Lyophilisation, freeze-drying or spray-drying

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Botany (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Medical Informatics (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Birds (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Dermatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Cosmetics (AREA)

Abstract

The present invention relates to a novel use of Rubia Cordifolia root extract, and more specifically, relates to a composition for preventing and treating brain cancer, the composition comprising Rubia Cordifolia root ethanol extract as an active ingredient, and to a cosmetic composition for preventing brain cancer, the cosmetic composition comprising the Rubia Cordifolia root ethanol extract, which includes a cosmetologically acceptable cosmetic supplement additive, as an active ingredient. The composition and the cosmetic composition for treating brain cancer according to the present invention are effective in inhibiting growth and inducing death of cancer cells, and thereby, can be effectively used in treating and preventing brain cancer.
PCT/KR2012/001080 2011-02-11 2012-02-13 Composition and cosmetic composition for treating brain cancer comprising rubia cordifolia root extract Ceased WO2012108746A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR10-2011-0012219 2011-02-11
KR1020110012219A KR20120092280A (en) 2011-02-11 2011-02-11 Composition for treatment of brain cancers and beauty expenses composition comprising extract of rubiae radix

Publications (2)

Publication Number Publication Date
WO2012108746A2 WO2012108746A2 (en) 2012-08-16
WO2012108746A3 true WO2012108746A3 (en) 2012-12-20

Family

ID=46639101

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/KR2012/001080 Ceased WO2012108746A2 (en) 2011-02-11 2012-02-13 Composition and cosmetic composition for treating brain cancer comprising rubia cordifolia root extract

Country Status (2)

Country Link
KR (1) KR20120092280A (en)
WO (1) WO2012108746A2 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2014077432A1 (en) * 2012-11-16 2014-05-22 주식회사 한국전통의학연구소 Composition containing rubiae radix extract for renal cancer treatment and cosmetics
IL278906B2 (en) * 2018-06-01 2024-08-01 Univ Yale Compositions and methods for treating steroid hormone-related diseases or disorders

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040105902A1 (en) * 2002-12-02 2004-06-03 Jiafang Chen Compositions and methods for treating prostate cancer
KR100485133B1 (en) * 2001-12-27 2005-04-22 류종훈 Composition containing an extract of rubiae radix for protecting brain cells and treating brain stroke
KR100750873B1 (en) * 2005-07-22 2007-08-22 건국대학교 산학협력단 Cheoncho-geun extract and pharmaceutical composition for the prevention and treatment of allergic diseases including the same

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100485133B1 (en) * 2001-12-27 2005-04-22 류종훈 Composition containing an extract of rubiae radix for protecting brain cells and treating brain stroke
US20040105902A1 (en) * 2002-12-02 2004-06-03 Jiafang Chen Compositions and methods for treating prostate cancer
KR100750873B1 (en) * 2005-07-22 2007-08-22 건국대학교 산학협력단 Cheoncho-geun extract and pharmaceutical composition for the prevention and treatment of allergic diseases including the same

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
CHOI, HO SEUNG ET AL.: "Influence of Rubiae Radix Extract on the Mechanism of Apoptosis in HL-60 Cells.", KOREAN JOURNAL OF ORIENTAL PHYSIOLOGY & PATHOLOGY., vol. 22, no. 3, 2008, pages 548 - 555 *

Also Published As

Publication number Publication date
KR20120092280A (en) 2012-08-21
WO2012108746A2 (en) 2012-08-16

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