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WO2012161497A3 - 보습능이 우수한 펩타이드 유도체 및 이의 용도 - Google Patents

보습능이 우수한 펩타이드 유도체 및 이의 용도 Download PDF

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Publication number
WO2012161497A3
WO2012161497A3 PCT/KR2012/004029 KR2012004029W WO2012161497A3 WO 2012161497 A3 WO2012161497 A3 WO 2012161497A3 KR 2012004029 W KR2012004029 W KR 2012004029W WO 2012161497 A3 WO2012161497 A3 WO 2012161497A3
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WO
WIPO (PCT)
Prior art keywords
peptide derivatives
derivatives
moisturizing effect
salts
superior moisturizing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/KR2012/004029
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English (en)
French (fr)
Other versions
WO2012161497A2 (ko
Inventor
박기돈
임채진
윤석정
권선덕
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
INCOSPHARM CORP
Original Assignee
INCOSPHARM CORP
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by INCOSPHARM CORP filed Critical INCOSPHARM CORP
Priority to ES12789455.8T priority Critical patent/ES2639999T3/es
Priority to EP12789455.8A priority patent/EP2716651B1/en
Priority to US14/119,854 priority patent/US9359401B2/en
Priority to JP2014512756A priority patent/JP5781224B2/ja
Publication of WO2012161497A2 publication Critical patent/WO2012161497A2/ko
Publication of WO2012161497A3 publication Critical patent/WO2012161497A3/ko
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/10—Tetrapeptides
    • C07K5/1019—Tetrapeptides with the first amino acid being basic
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/05—Dipeptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/06—Tripeptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/07—Tetrapeptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/04—Antipruritics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A61Q19/08—Anti-ageing preparations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q5/00—Preparations for care of the hair
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/001—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof by chemical synthesis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C07K5/0215—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing natural amino acids, forming a peptide bond via their side chain functional group, e.g. epsilon-Lys, gamma-Glu
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06086—Dipeptides with the first amino acid being basic
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06104—Dipeptides with the first amino acid being acidic
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08—Tripeptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08—Tripeptides
    • C07K5/0819—Tripeptides with the first amino acid being acidic
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/10—Tetrapeptides
    • C07K5/1021—Tetrapeptides with the first amino acid being acidic
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A61Q19/007—Preparations for dry skin

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Dermatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Birds (AREA)
  • Gerontology & Geriatric Medicine (AREA)
  • Pulmonology (AREA)
  • Peptides Or Proteins (AREA)
  • Cosmetics (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

본 발명은 보습능이 우수한 펩타이드 유도체 또는 이의 약학적으로 허용되는 염 및 이의 보습 용도에 관한 것이다. 보다 구체적으로, 본 발명은 신규 펩타이드 유도체 또는 이의 약학적으로 허용되는 염, 이들의 제조방법, 이를 유효성분으로 함유하는 보습용 화장료 조성물 및 피부 건조증 예방 및 치료용 약학 조성물에 관한 것이다.
PCT/KR2012/004029 2011-05-23 2012-05-22 보습능이 우수한 펩타이드 유도체 및 이의 용도 Ceased WO2012161497A2 (ko)

Priority Applications (4)

Application Number Priority Date Filing Date Title
ES12789455.8T ES2639999T3 (es) 2011-05-23 2012-05-22 Derivados peptídicos que tienen un efecto hidratante superior y usos de los mismos
EP12789455.8A EP2716651B1 (en) 2011-05-23 2012-05-22 Peptide derivatives having a superior moisturizing effect and uses thereof
US14/119,854 US9359401B2 (en) 2011-05-23 2012-05-22 Peptide analogues with an excellent moisturizing effect and use thereof
JP2014512756A JP5781224B2 (ja) 2011-05-23 2012-05-22 保湿能に優れたペプチド誘導体およびその用途

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR1020110048722A KR101384744B1 (ko) 2011-05-23 2011-05-23 보습능이 우수한 펩타이드 유도체 및 이의 용도
KR10-2011-0048722 2011-05-23

Publications (2)

Publication Number Publication Date
WO2012161497A2 WO2012161497A2 (ko) 2012-11-29
WO2012161497A3 true WO2012161497A3 (ko) 2013-01-17

Family

ID=47217888

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/KR2012/004029 Ceased WO2012161497A2 (ko) 2011-05-23 2012-05-22 보습능이 우수한 펩타이드 유도체 및 이의 용도

Country Status (6)

Country Link
US (1) US9359401B2 (ko)
EP (1) EP2716651B1 (ko)
JP (1) JP5781224B2 (ko)
KR (1) KR101384744B1 (ko)
ES (1) ES2639999T3 (ko)
WO (1) WO2012161497A2 (ko)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101705338B1 (ko) * 2015-10-26 2017-02-09 주식회사 인코스팜 항산화, 항노화 및 자가포식 활성을 가지는 조성물 및 이의 용도
KR101796479B1 (ko) * 2016-06-24 2017-11-13 주식회사 인코스팜 피부 염증 또는 노화를 개선하는 신규 자가포식작용 활성화 유도 화합물
KR102006241B1 (ko) * 2017-04-20 2019-08-01 주식회사 인코스팜 아디포넥틴의 발현증가 유도 화합물을 포함하는 항노화용 또는 피부 붉은기 완화용 화장료 조성물, 및 피부 염증질환의 예방 및 치료용 의약 조성물
US9920092B1 (en) * 2017-06-09 2018-03-20 Incospharm Corporation Composition having anti-oxidant, anti-aging, and autophagy activities and uses thereof
KR102203722B1 (ko) * 2018-06-18 2021-01-15 주식회사 인코스팜 신규한 화합물, 이를 포함하는 화장료 조성물 및 약학적 조성물
KR102400269B1 (ko) * 2018-09-19 2022-05-20 주식회사 차메디텍 피부 보습을 향상시키는 펩타이드 유도체 및 이의 제조 방법
KR20200064762A (ko) 2018-11-29 2020-06-08 주식회사 인코스팜 여드름 개선 화장료 및 치료용 약학 조성물
KR102096600B1 (ko) 2018-11-29 2020-05-27 주식회사 인코스팜 자가포식 활성 유도 화합물을 포함하는 여드름 피부의 염증 개선 화장료 및 치료용 약학 조성물
KR102506099B1 (ko) * 2022-09-22 2023-03-08 주식회사 에스윤글로벌 피부 탄력, 보습, 미백, 노화 방지 및 주름 개선 효과가 우수한 화장료 조성물

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US20110045036A1 (en) * 2006-05-05 2011-02-24 Sederma Cosmetic Compositions Comprising at Least One Peptide with at Least One Immobilized Aromatic Cycle

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US4032676A (en) * 1973-12-24 1977-06-28 Henkel & Cie G.M.B.H. N-polyhydroxyalkyl-amino acids, their manufacture and skin treating agents containing the same
US20080025932A1 (en) * 2001-03-22 2008-01-31 Bissett Donald L Skin care compositions containing a sugar amine
US7671009B2 (en) * 2001-10-30 2010-03-02 Dsm Ip Assets B.V. Dermopharmaceutically and cosmetically active oligopeptides
US20040241114A1 (en) * 2003-05-30 2004-12-02 Gupta Shyam K. Hair Care and Nail Care Compositions Based on Ion-Pair Delivery System for Gender and Ethnic Selective Applications
US20110045036A1 (en) * 2006-05-05 2011-02-24 Sederma Cosmetic Compositions Comprising at Least One Peptide with at Least One Immobilized Aromatic Cycle

Also Published As

Publication number Publication date
ES2639999T3 (es) 2017-10-31
US20140113868A1 (en) 2014-04-24
EP2716651A4 (en) 2014-10-15
KR20120130631A (ko) 2012-12-03
EP2716651A2 (en) 2014-04-09
JP5781224B2 (ja) 2015-09-16
EP2716651B1 (en) 2017-06-21
WO2012161497A2 (ko) 2012-11-29
JP2014516972A (ja) 2014-07-17
KR101384744B1 (ko) 2014-04-14
US9359401B2 (en) 2016-06-07

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