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WO2012161489A3 - 리바스티그민 함유 패취 - Google Patents

리바스티그민 함유 패취 Download PDF

Info

Publication number
WO2012161489A3
WO2012161489A3 PCT/KR2012/003986 KR2012003986W WO2012161489A3 WO 2012161489 A3 WO2012161489 A3 WO 2012161489A3 KR 2012003986 W KR2012003986 W KR 2012003986W WO 2012161489 A3 WO2012161489 A3 WO 2012161489A3
Authority
WO
WIPO (PCT)
Prior art keywords
patch containing
containing rivastigmine
rivastigmine
patch
storage stability
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/KR2012/003986
Other languages
English (en)
French (fr)
Other versions
WO2012161489A2 (ko
Inventor
황용연
최원재
김재선
윤원노
박여진
오준교
임종섭
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
SK Chemicals Co Ltd
Original Assignee
SK Chemicals Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by SK Chemicals Co Ltd filed Critical SK Chemicals Co Ltd
Priority to JP2014511305A priority Critical patent/JP6017543B2/ja
Priority to BR112013029945A priority patent/BR112013029945A2/pt
Priority to US14/118,985 priority patent/US9585862B2/en
Priority to EP12789117.4A priority patent/EP2711002A4/en
Publication of WO2012161489A2 publication Critical patent/WO2012161489A2/ko
Publication of WO2012161489A3 publication Critical patent/WO2012161489A3/ko
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/325—Carbamic acids; Thiocarbamic acids; Anhydrides or salts thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/27—Esters, e.g. nitroglycerine, selenocyanates of carbamic or thiocarbamic acids, meprobamate, carbachol, neostigmine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
    • A61K9/7053—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
    • A61K9/7061—Polyacrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7084—Transdermal patches having a drug layer or reservoir, and one or more separate drug-free skin-adhesive layers, e.g. between drug reservoir and skin, or surrounding the drug reservoir; Liquid-filled reservoir patches
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/42—Use of materials characterised by their function or physical properties
    • A61L15/44—Medicaments
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/42—Use of materials characterised by their function or physical properties
    • A61L15/58—Adhesives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Dermatology (AREA)
  • Hematology (AREA)
  • Materials Engineering (AREA)
  • Emergency Medicine (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)

Abstract

본 발명은 보관 안정성이 향상되고, 적절한 방출성을 가지는 리바스티그민 함유 패취에 관한 것이다.
PCT/KR2012/003986 2011-05-20 2012-05-21 리바스티그민 함유 패취 Ceased WO2012161489A2 (ko)

Priority Applications (4)

Application Number Priority Date Filing Date Title
JP2014511305A JP6017543B2 (ja) 2011-05-20 2012-05-21 リバスティグミン含有パッチ
BR112013029945A BR112013029945A2 (pt) 2011-05-20 2012-05-21 emplastro contendo rivastigmina
US14/118,985 US9585862B2 (en) 2011-05-20 2012-05-21 Patch containing rivastigmine
EP12789117.4A EP2711002A4 (en) 2011-05-20 2012-05-21 PLASTER WITH RIVASTIGMIN

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR10-2011-0048068 2011-05-20
KR20110048068 2011-05-20

Publications (2)

Publication Number Publication Date
WO2012161489A2 WO2012161489A2 (ko) 2012-11-29
WO2012161489A3 true WO2012161489A3 (ko) 2013-01-17

Family

ID=47217881

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/KR2012/003986 Ceased WO2012161489A2 (ko) 2011-05-20 2012-05-21 리바스티그민 함유 패취

Country Status (5)

Country Link
US (1) US9585862B2 (ko)
EP (1) EP2711002A4 (ko)
JP (1) JP6017543B2 (ko)
BR (1) BR112013029945A2 (ko)
WO (1) WO2012161489A2 (ko)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20140038237A (ko) * 2012-09-20 2014-03-28 에스케이케미칼주식회사 리바스티그민의 안정성이 개선된 의약품
CN103431846B (zh) * 2013-09-18 2015-11-18 天津工业大学 智能睡眠监控系统
JP6100150B2 (ja) * 2013-12-06 2017-03-22 久光製薬株式会社 ４−アミノピリジン含有貼付剤
US20160374956A1 (en) * 2013-12-12 2016-12-29 Hisamitsu Pharmaceutical Co., Inc. Multilayer type patch
CN106413695B (zh) 2014-04-08 2019-12-10 帝国制药美国公司 利伐斯的明透皮组合物及其使用方法
WO2016052522A1 (ja) * 2014-09-30 2016-04-07 ニプロ株式会社 経皮投与製剤及び包装体
JP6940407B2 (ja) * 2014-12-19 2021-09-29 キンデーバ ドラッグ デリバリー リミティド パートナーシップ フェンタニルを含む経皮薬物送達デバイス
JP6654365B2 (ja) * 2015-06-17 2020-02-26 日東電工株式会社 貼付製剤
KR102823139B1 (ko) * 2018-08-31 2025-06-19 에스케이케미칼 주식회사 장기 투여용 리바스티그민 패취
WO2025038382A1 (en) 2023-08-11 2025-02-20 Momentive Performance Materials Inc. Pharmaceutical adhesive compositions

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6335031B1 (en) * 1998-01-12 2002-01-01 Novartis Ag TTS containing an antioxidant
US20040258741A1 (en) * 2001-10-17 2004-12-23 Takaaki Terahara Percutaneous absorption preparations
WO2007064407A1 (en) * 2005-12-01 2007-06-07 Novartis Ag Transdermal therapeutic system
US20070259028A1 (en) * 2006-05-08 2007-11-08 Takeshi Ito Percutaneous absorption preparations of antidementia drugs
KR20100080681A (ko) * 2009-01-02 2010-07-12 대화제약 주식회사 리바스티그민의 간단한 경피흡수제

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3615727A (en) * 1967-03-23 1971-10-26 Armin Starke Method of preserving
HU201906B (en) 1987-03-04 1991-01-28 Sandoz Ag Process for producing phenyl-carbamate derivative and acid additional salts and pharmaceutical compositions containing them
EP2078524B1 (en) 2006-10-27 2016-08-31 Hisamitsu Pharmaceutical Co., Inc. Adhesive skin patch
US20100087768A1 (en) * 2008-10-02 2010-04-08 Forlano Paula Transdermal drug delivery system for liquid active ingredient
EP2298277A1 (en) * 2009-09-09 2011-03-23 Labtec GmbH Transdermal patch formulation
CN102548544B (zh) * 2009-10-09 2015-01-21 永进药品工业株式会社 同时具有速效特性和长效特性的药物组合物
US8962014B2 (en) * 2009-12-22 2015-02-24 Acino Ag Transdermal therapeutic system for administering rivastigmine or derivatives thereof
KR101054317B1 (ko) * 2011-01-28 2011-08-08 신신제약 주식회사 리바스티그민을 함유하는 경피흡수제제

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6335031B1 (en) * 1998-01-12 2002-01-01 Novartis Ag TTS containing an antioxidant
US20040258741A1 (en) * 2001-10-17 2004-12-23 Takaaki Terahara Percutaneous absorption preparations
WO2007064407A1 (en) * 2005-12-01 2007-06-07 Novartis Ag Transdermal therapeutic system
US20070259028A1 (en) * 2006-05-08 2007-11-08 Takeshi Ito Percutaneous absorption preparations of antidementia drugs
KR20100080681A (ko) * 2009-01-02 2010-07-12 대화제약 주식회사 리바스티그민의 간단한 경피흡수제

Also Published As

Publication number Publication date
JP6017543B2 (ja) 2016-11-02
WO2012161489A2 (ko) 2012-11-29
JP2014513719A (ja) 2014-06-05
EP2711002A4 (en) 2014-10-29
US20140220104A1 (en) 2014-08-07
US9585862B2 (en) 2017-03-07
EP2711002A2 (en) 2014-03-26
BR112013029945A2 (pt) 2017-01-31

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