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WO2012039679A3 - System for near-infrared autofluorescence measurement of a subject, and method thereof - Google Patents

System for near-infrared autofluorescence measurement of a subject, and method thereof Download PDF

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Publication number
WO2012039679A3
WO2012039679A3 PCT/SG2011/000322 SG2011000322W WO2012039679A3 WO 2012039679 A3 WO2012039679 A3 WO 2012039679A3 SG 2011000322 W SG2011000322 W SG 2011000322W WO 2012039679 A3 WO2012039679 A3 WO 2012039679A3
Authority
WO
WIPO (PCT)
Prior art keywords
subject
infrared
excitation light
processing section
autofluorescence
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/SG2011/000322
Other languages
French (fr)
Other versions
WO2012039679A2 (en
Inventor
Zhiwei Huang
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
National University of Singapore
Original Assignee
National University of Singapore
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by National University of Singapore filed Critical National University of Singapore
Publication of WO2012039679A2 publication Critical patent/WO2012039679A2/en
Publication of WO2012039679A3 publication Critical patent/WO2012039679A3/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B1/00—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
    • A61B1/31—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor for the rectum, e.g. proctoscopes, sigmoidoscopes, colonoscopes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B1/00—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
    • A61B1/00163—Optical arrangements
    • A61B1/00165—Optical arrangements with light-conductive means, e.g. fibre optics
    • A61B1/00167—Details of optical fibre bundles, e.g. shape or fibre distribution
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B1/00—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
    • A61B1/04—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor combined with photographic or television appliances
    • A61B1/043—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor combined with photographic or television appliances for fluorescence imaging

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Surgery (AREA)
  • Optics & Photonics (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Medical Informatics (AREA)
  • Radiology & Medical Imaging (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pathology (AREA)
  • Molecular Biology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)

Abstract

A system for near-infrared autofluorescence measurement of a subject, the system comprising: a light source configured to emit an excitation light at near-infrared; a medium configured for delivering the excitation light to the subject; and a processing section for processing an autofluorescence signal from the subject at near-infrared resulting from the excitation light impinging upon the subject so as to analyze the subject. For example, the processing section comprises a spectrometer for detecting the autofluorescence signal at near-infrared to analyze the subject. As another example, the processing section comprises an image sensor for generating an image based on the autofluorescence signal.
PCT/SG2011/000322 2010-09-22 2011-09-20 System for near-infrared autofluorescence measurement of a subject, and method thereof Ceased WO2012039679A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SG2010069227A SG179311A1 (en) 2010-09-22 2010-09-22 Methods and apparatus relating to integrated nir fluorescence and reflectance imaging and spectroscopy with polarization for improving tissue diagnosis and characterization
SG201006922-7 2010-09-22

Publications (2)

Publication Number Publication Date
WO2012039679A2 WO2012039679A2 (en) 2012-03-29
WO2012039679A3 true WO2012039679A3 (en) 2012-07-26

Family

ID=45874264

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/SG2011/000322 Ceased WO2012039679A2 (en) 2010-09-22 2011-09-20 System for near-infrared autofluorescence measurement of a subject, and method thereof

Country Status (2)

Country Link
SG (1) SG179311A1 (en)
WO (1) WO2012039679A2 (en)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103263244A (en) * 2013-05-27 2013-08-28 上海大学 Endoscope device using single optical fiber to achieving imaging
CN103271714A (en) * 2013-05-27 2013-09-04 上海大学 Microcosmic fiber optic endoscope
US9804145B2 (en) * 2013-05-28 2017-10-31 Todos Medical Ltd. Infrared analysis of benign tumors
CN103705201B (en) * 2014-01-16 2015-11-04 福建师范大学 A multi-mode spectral analysis system suitable for the detection of gastrointestinal lesions
GB201415439D0 (en) * 2014-09-01 2014-10-15 Univ Singapore A pressure-sensitive fiber optic probe for real-time in vivo tissue optical spectroscopy,a system incorporating the same and a method for using the same
US11033225B2 (en) * 2015-05-27 2021-06-15 Shimadzu Corporation Brain activity feedback system
EP3430381A1 (en) * 2016-03-14 2019-01-23 Massachusetts Institute Of Technology Device and method for imaging shortwave infrared fluorescence
WO2017212307A1 (en) 2016-06-06 2017-12-14 Hajdu Imre Diagnostic medical device
US11147453B2 (en) 2017-10-03 2021-10-19 Canon U.S.A., Inc. Calibration for OCT-NIRAF multimodality probe
US11982621B2 (en) 2022-10-01 2024-05-14 Photothermal Spectroscopy Corp. Autofluorescence photothermal characterization systems and methods

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004031746A1 (en) * 2002-10-02 2004-04-15 Lumen Health Innovations, Inc. Apparatus and methods relating to high speed spectroscopy and excitation-emission matrices
WO2010014847A1 (en) * 2008-07-30 2010-02-04 Vanderbilt University Intra-operative fluorescence spectroscopy and applications of same

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004031746A1 (en) * 2002-10-02 2004-04-15 Lumen Health Innovations, Inc. Apparatus and methods relating to high speed spectroscopy and excitation-emission matrices
WO2010014847A1 (en) * 2008-07-30 2010-02-04 Vanderbilt University Intra-operative fluorescence spectroscopy and applications of same

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
HUANG, Z. ET AL.: "Raman Spectroscopy in Combination with Background Near- infrared Autofluorescence Enhances the In Vivo Assessment of Malignant Tissues", PHOTOCHEMISTRY AND PHOTOBIOLOGY, vol. 81, 2005, pages 1219 - 1226 *

Also Published As

Publication number Publication date
SG179311A1 (en) 2012-04-27
WO2012039679A2 (en) 2012-03-29

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