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WO2012036518A3 - Nouveau composé à activité antibiotique et composition antibiotique comprenant le composé - Google Patents

Nouveau composé à activité antibiotique et composition antibiotique comprenant le composé Download PDF

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Publication number
WO2012036518A3
WO2012036518A3 PCT/KR2011/006879 KR2011006879W WO2012036518A3 WO 2012036518 A3 WO2012036518 A3 WO 2012036518A3 KR 2011006879 W KR2011006879 W KR 2011006879W WO 2012036518 A3 WO2012036518 A3 WO 2012036518A3
Authority
WO
WIPO (PCT)
Prior art keywords
compound
antibiotic composition
antibiotically active
active compound
novel
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/KR2011/006879
Other languages
English (en)
Korean (ko)
Other versions
WO2012036518A2 (fr
Inventor
강린우
김정구
안예진
이병무
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University Industry Cooperation Corporation of Konkuk University
Korea Rural Development Administration
Original Assignee
University Industry Cooperation Corporation of Konkuk University
Korea Rural Development Administration
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University Industry Cooperation Corporation of Konkuk University, Korea Rural Development Administration filed Critical University Industry Cooperation Corporation of Konkuk University
Publication of WO2012036518A2 publication Critical patent/WO2012036518A2/fr
Publication of WO2012036518A3 publication Critical patent/WO2012036518A3/fr
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/32—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D207/33—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms with substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D207/333—Radicals substituted by oxygen or sulfur atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)

Abstract

La présente invention concerne un nouveau composé à activité antibiotique et une composition antibiotique comprenant le composé, et concerne plus spécifiquement un composé qui inhibe la croissance de cellules bactériennes et une utilisation du composé.
PCT/KR2011/006879 2010-09-17 2011-09-16 Nouveau composé à activité antibiotique et composition antibiotique comprenant le composé Ceased WO2012036518A2 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR1020100092037A KR101156666B1 (ko) 2010-09-17 2010-09-17 신규한 항생활성 화합물 및 그 화합물을 포함하는 항생 조성물
KR10-2010-0092037 2010-09-17

Publications (2)

Publication Number Publication Date
WO2012036518A2 WO2012036518A2 (fr) 2012-03-22
WO2012036518A3 true WO2012036518A3 (fr) 2012-06-07

Family

ID=45832134

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/KR2011/006879 Ceased WO2012036518A2 (fr) 2010-09-17 2011-09-16 Nouveau composé à activité antibiotique et composition antibiotique comprenant le composé

Country Status (2)

Country Link
KR (1) KR101156666B1 (fr)
WO (1) WO2012036518A2 (fr)

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5418218A (en) * 1992-07-10 1995-05-23 The University Of Maryland At Baltimore Histidyl-proline diketopiperazine (cyclo his-pro) a cns-active pharmacologic agent
US20030225103A1 (en) * 2000-08-04 2003-12-04 Dmi Biosciences, Inc. Method of using diketopiperazines and composition containing them
US20050119177A1 (en) * 2003-05-15 2005-06-02 David Bar-Or Treatment of T-cell mediated diseases

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002010156A1 (fr) 2000-07-29 2002-02-07 Arpida Ag Derives de benzofuranne et leur utilisation en tant qu'agents antibacteriens
KR20080041722A (ko) * 2005-08-31 2008-05-13 와이어쓰 글리실사이클린의 9-아미노카르보닐 치환된 유도체

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5418218A (en) * 1992-07-10 1995-05-23 The University Of Maryland At Baltimore Histidyl-proline diketopiperazine (cyclo his-pro) a cns-active pharmacologic agent
US20030225103A1 (en) * 2000-08-04 2003-12-04 Dmi Biosciences, Inc. Method of using diketopiperazines and composition containing them
US20050119177A1 (en) * 2003-05-15 2005-06-02 David Bar-Or Treatment of T-cell mediated diseases

Non-Patent Citations (5)

* Cited by examiner, † Cited by third party
Title
EVANS ET AL.: "Metabolic effects of platelet-activating factor in rats in vivo: Stimulation of hepatic glycogenolysis and lipogenesis", BIOCHEM. J., vol. 269, no. 1, 1 July 1990 (1990-07-01), pages 269 - 272 *
GOUNTOPOULOU ET AL.: "TNF is a potent inducer of platelet-activating factor synthesis in adipocytes but not in preadipocytes: Differential regulation by PI3K", CYTOKINE, vol. 41, no. 2, 3 January 2008 (2008-01-03), pages 174 - 181, XP022458537, DOI: doi:10.1016/j.cyto.2007.11.008 *
HANSEL ET AL.: "Metabolic Syndrome Is Associated with Elevated Oxidative Stress and Dysfunctional Dense High-Density Lipoprotein Particles Displaying Impaired Antioxidative Activity", J CLIN ENDOCRINOL METAB, vol. 89, no. 10, 1 October 2004 (2004-10-01), pages 4963 - 4971 *
IYER ET AL.: "Inflammatory lipid mediators in adipocyte function and obesity", NATURE REVIEWS ENDOCRINOLOGY, vol. 6, 1 February 2010 (2010-02-01), pages 71 - 82, XP055212341, DOI: doi:10.1038/nrendo.2009.264 *
YANG ET AL.: "Increased hepatic platelet activating factor (PAF) and PAF receptors in carbon tetrachloride induced liver cirrhosis", GUT, vol. 53, no. 6, 1 January 2004 (2004-01-01), pages 877 - 883 *

Also Published As

Publication number Publication date
KR101156666B1 (ko) 2012-06-15
KR20120029908A (ko) 2012-03-27
WO2012036518A2 (fr) 2012-03-22

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