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WO2012029383A1 - Compresse de coton hémostatique et procédé de production de celle-ci - Google Patents

Compresse de coton hémostatique et procédé de production de celle-ci Download PDF

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Publication number
WO2012029383A1
WO2012029383A1 PCT/JP2011/064383 JP2011064383W WO2012029383A1 WO 2012029383 A1 WO2012029383 A1 WO 2012029383A1 JP 2011064383 W JP2011064383 W JP 2011064383W WO 2012029383 A1 WO2012029383 A1 WO 2012029383A1
Authority
WO
WIPO (PCT)
Prior art keywords
hemostatic cotton
hemostatic
groove
compressed
compression
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/JP2011/064383
Other languages
English (en)
Japanese (ja)
Inventor
昭洋 山口
隆仁郎 寺井
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
MASANO CO Ltd
OZU Corp
Original Assignee
MASANO CO Ltd
OZU Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by MASANO CO Ltd, OZU Corp filed Critical MASANO CO Ltd
Priority to JP2012531723A priority Critical patent/JP5082027B2/ja
Priority to CN2011800413738A priority patent/CN103068350A/zh
Publication of WO2012029383A1 publication Critical patent/WO2012029383A1/fr
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F13/00—Bandages or dressings; Absorbent pads
    • A61F13/01—Non-adhesive bandages or dressings
    • A61F13/01008—Non-adhesive bandages or dressings characterised by the material
    • A61F13/01012—Non-adhesive bandages or dressings characterised by the material being made of natural material, e.g. cellulose-, protein-, collagen-based
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F13/00—Bandages or dressings; Absorbent pads
    • A61F13/02—Adhesive bandages or dressings
    • A61F13/0276—Apparatus or processes for manufacturing adhesive dressings or bandages
    • A61F13/0286—Apparatus or processes for manufacturing adhesive dressings or bandages manufacturing of non adhesive dressings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F13/00—Bandages or dressings; Absorbent pads
    • A61F13/15—Absorbent pads, e.g. sanitary towels, swabs or tampons for external or internal application to the body; Supporting or fastening means therefor; Tampon applicators
    • A61F13/36—Surgical swabs, e.g. for absorbency or packing body cavities during surgery
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F13/00—Bandages or dressings; Absorbent pads
    • A61F2013/00089—Wound bandages
    • A61F2013/00314—Wound bandages with surface treatments
    • A61F2013/00327—Wound bandages with surface treatments to create projections or depressions in surface

Definitions

  • the present invention relates to a compressed hemostatic cotton and a method for producing the same.
  • a compressed hemostatic cotton when using an arteriovenous indwelling needle for artificial dialysis, injection, infusion, blood collection, etc., it is excellent in workability when removing the injection needle as the inner needle and the plastic tube as the outer needle from the puncture part.
  • the present invention also relates to a compressed hemostatic cotton that exerts an excellent compression hemostatic effect on a puncture site and a method for producing the same.
  • a hemostatic pad has been proposed as a hemostatic pad for the purpose of making it difficult for the hemostatic pad to roll on the human body and to easily press the puncture portion.
  • the hemostasis pad 200 is characterized in that both surfaces 220 of the compression part are spherical convex surfaces, and a collar 230 protrudes from the outer periphery of the compression part 210 having a meteorite shape to form a meteorite shape with a collar (for example, , See Patent Document 1).
  • a hemostatic pad As a hemostatic pad, a hemostatic pad has been proposed for the purpose of eliminating the work by the finger pressure method and enhancing the hemostatic effect by filling the inside with a transparent silicone gel. More specifically, as shown in FIG. 5B, the lower end opening of the pad main body 320 formed by a transparent plastic film 310 in a dome shape having a lower end opening and filled with silicone gel 330 is the opening. This is a hemostatic pad 300 that is detachably connected to a plastic sheet 340 disposed so as to cover a part (see, for example, Patent Document 2).
  • both surfaces of the compression portion are spherical convex surfaces, there is an advantage that the puncture portion is intensively and easily compressed, but when the needle is removed, the spherical convex shape is provided. Since there are no guides or grooves on the surface to make it easy to remove the needle, it is necessary to pay more attention to the extraction of the needle so that blood does not leak.
  • the hemostatic pad disclosed in Patent Document 2 has a groove in the knob portion, so that the needle can be pulled out somewhat easily, but it is very expensive compared to compressed cotton and cannot be used easily. There was a problem.
  • the inventors of the present invention have made diligent efforts and found that the above-mentioned problems can be solved by making the surface pressing the hemostatic site into a predetermined shape and providing the predetermined groove on the surface. It has been completed. That is, the present invention can accurately cover the punctured portion of the injection needle or the like, and can efficiently compress and stop bleeding from the puncture portion due to the injection needle or the like, and is easy to remove the needle. Accordingly, it is an object of the present invention to provide a compressed hemostatic cotton that is excellent in workability and can be stably and inexpensively produced and a method for producing the same.
  • the present invention is a compression hemostatic cotton formed by integrally molding a fibrous material, and has a surface for compressing a predetermined hemostatic site, and a part of the surface is flat or curved, and
  • a compression tourniquet provided with a groove portion that engages with the injection needle or a plastic tube associated therewith on a part of the surface can be provided to solve the above-described problems. That is, by having a flat or curved surface, the puncture portion can be efficiently compressed, while by providing the groove portion, the compression hemostatic cotton can be accurately placed at a predetermined location before the needle is removed. In addition, workability such as punching can be improved. Therefore, the needle can be removed accurately and easily, and the puncture portion can be efficiently compressed and stopped.
  • the groove part of this invention is a concave-shaped part provided in the surface for pressing the predetermined hemostatic location of the compression hemostatic cotton.
  • the depth of the groove is preferably set to a value within the range of 0.1 to 1.5 mm.
  • the groove portion In constructing the compressed hemostatic cotton of the present invention, it is preferable that a plurality of groove portions are provided and the shapes of the plurality of groove portions are the same or different.
  • the groove portion By configuring the groove portion in this manner, the groove can be selected according to the thickness of the injection needle or the plastic tube, and blood can be efficiently stopped without leaking from the groove portion.
  • the fibrous material is preferably composed of a mixed nonwoven fabric of rayon fibers and polyester fibers.
  • the durometer hardness (type E) of the compressed hemostatic cotton it is preferable to set the durometer hardness (type E) of the compressed hemostatic cotton to a value in the range of 20 to 80 hardness by a measuring method based on JIS K6253.
  • the surface opposite to the surface for compressing a predetermined hemostatic site is flat.
  • the compressed hemostatic cotton of the present invention it is preferable to provide ribs at both ends of the compressed hemostatic cotton. By comprising in this way, stability at the time of pressing can be improved.
  • Another aspect of the present invention is as follows: A method for producing compressed hemostatic cotton obtained by integrally molding a fibrous material, A step of forming a fibrous material into a roll shape, a heat-compression molding of the rolled fibrous material, and a flat or curved surface for pressing a predetermined hemostatic site, and injection into a part of the surface And obtaining a compressed hemostatic cotton having a groove engaging with a needle or a plastic tube associated therewith.
  • the size of the hemostatic cotton can be easily controlled, and it can be produced efficiently and stably at a low cost.
  • FIGS. 1 (a) to 1 (d) are diagrams for explaining the compressed hemostatic cotton of the present invention.
  • FIGS. 2A and 2B are views for explaining an example of the compressed hemostatic cotton of the present invention.
  • FIGS. 3A to 3B are views for explaining an example of the compressed hemostatic cotton of the present invention.
  • 4 (a) and 4 (b) are diagrams for explaining the manufacturing process of the compressed hemostatic cotton of the present invention.
  • FIGS. 5A and 5B are views for explaining a conventional hemostatic pad.
  • the first embodiment is a compression hemostatic cotton formed by integrally molding a fibrous material, and has a surface for compressing a predetermined hemostatic site, and a part of the surface is flat or curved, And it is a compression hemostatic cotton provided with a groove part engaged with the injection needle or the plastic tube attached to it at a part of the surface.
  • the hemostatic cotton 10 is formed by integrally molding a fibrous material 20, and includes a groove portion 14, and the surface 12 including the groove portion is flat or curved. It is characterized by the shape.
  • Type of fibrous material The type of fibrous material constituting the compressed hemostatic cotton is not particularly limited, and for example, one type of rayon, polyester, cotton, polypropylene, polyester, nylon, acrylic, etc. These may be used alone or in combination of two or more. Further, the form of the fibrous material is not particularly limited, and may be a non-woven fabric, a woven fabric, or a mesh material.
  • the rayon fiber and the polyester fiber are in a predetermined ratio (for example, a weight ratio of 10:90 to 90:10 is preferable, a weight ratio of 20:80 to 80:20 is more preferable, and 30:70 to 70: It is preferable to use a non-woven fabric obtained by blending with a weight ratio of 30).
  • a weight ratio of 10:90 to 90:10 is preferable
  • a weight ratio of 20:80 to 80:20 is more preferable
  • a non-woven fabric obtained by blending with a weight ratio of 30.
  • the polyester fiber acts as a binder for the rayon fiber at the time of molding, and after molding the compressed hemostatic cotton having a suitable water absorption and water repellency. This is because it can be done.
  • the compression hemostatic cotton of the present invention is obtained by integrally molding the fibrous material 20, and is used for compressing a predetermined portion.
  • the surface 12 is flat or curved. The reason for this is that by using such a shape, the vicinity of the bleeding site can be effectively compressed, and hemostasis can be performed in a shorter time.
  • the surface 18 on the opposite side to the surface for pressing a predetermined location is not particularly limited, and may be flat or curved.
  • the reason for this is that, for example, as shown in FIG. 1 (c), when the surface 18 opposite to the surface for compressing the predetermined portion is curved, it is easy to compress the hemostatic portion intensively, This is because it is easy to fix the hemostatic cotton with a tape or a band after the hemostatic cotton is installed in the hemostatic part.
  • flanges 16 at both ends of the compressed hemostatic cotton.
  • the reason for this is that by providing the collar, the compressed hemostatic cotton is difficult to roll from above the affected area, and workability can be improved.
  • the shape of the collar is not particularly limited.
  • the size of the fibrous material is not particularly limited, and may be, for example, a value within the range of 1 to 5 cm in width, 1 to 7 cm in length, and 0.1 to 10 mm in thickness. It is preferable to do. This is because such a size is easy to use and can improve workability.
  • the surface state of the compressed hemostatic cotton is not particularly limited, and for example, it is preferable to have an embossed shape with irregularities on the surface.
  • the reason for this is not only that the surface area increases, but the water absorption is improved and blood can be prevented from leaking, and the softness of the compressed hemostatic cotton is visually recognized. It is because it can be made.
  • a groove 14 that engages with the injection needle or a plastic tube associated therewith is provided on the surface for compressing a predetermined hemostatic site in the compressed hemostatic cotton. It is characterized by that. The reason for this is that by having a groove portion, the compression hemostatic cotton can not only be easily installed when the syringe needle or the plastic tube attached thereto is stuck, but also when the needle is removed. This is because the guide can be easily removed and the working efficiency can be improved.
  • the depth (h) of the groove provided in the compressed hemostatic cotton is set to a value within the range of 0.1 to 1.5 mm. This is because, when the depth is less than 0.1 mm, it becomes difficult to engage with the injection needle or the plastic tube associated therewith, and blood from the bleeding part may leak. On the other hand, when the depth exceeds 1.5 mm, a gap is generated when the needle is engaged with the injection needle or the plastic tube attached thereto, and not only the hemostatic effect is lowered, but also blood may leak. . Therefore, it is more preferable that the depth of the groove is in the range of 0.5 to 1.0 mm. And according to the shape of an injection needle, the depth of the part engaged with the front-end
  • the depth of the groove provided in the compressed hemostatic cotton is, for example, as shown in FIGS. 1 (a) to 1 (d), when the groove has a uniform depth. In the case of a shape, it means the distance to the highest part).
  • the average value of the depth of the deepest part and the shallowest part means the depth of the groove.
  • the depth of each groove portion is set to a value within the above predetermined range.
  • the depth excluding the blood pool is a value within the above predetermined range.
  • the width (w) of the groove provided in the compressed hemostatic cotton is preferably set to a value in the range of 0.1 to 3.0 mm. This is because, when the width is less than 0.1 mm, it is difficult to engage with the injection needle or the plastic tube attached thereto, and blood from the bleeding part may leak. On the other hand, when the depth exceeds 3.0 mm, a gap is generated when the needle is engaged with the injection needle or the plastic tube attached thereto, and not only the hemostatic effect is lowered but also blood may leak. . Furthermore, the hemostatic surface becomes narrow, and it is difficult to effectively stop the hemostasis. Therefore, it is more preferable that the depth of the groove is in the range of 0.5 to 2.0 mm. In accordance with the shape of the injection needle, the width of the portion engaging with the tip of the injection needle can be narrowed, and the width of the portion engaging with the base of the injection needle can be increased.
  • the width of the groove means the distance between the contact points between the hemostatic site compression surface and the groove. ing.
  • the width of the groove means the distance between the highest portions of the hemostatic site compression surface.
  • the average value of the widths of the widest part and the narrowest part means the width of the groove.
  • the width of each groove portion is a value within the above predetermined range.
  • the width excluding the blood pool is a value within the above predetermined range.
  • the number of grooves provided in the compressed hemostatic cotton is not particularly limited.
  • the central portion of the surface 12 for compressing a predetermined hemostatic site as shown in FIG. It is preferable to provide one. This is because the hemostatic part can be intensively compressed by configuring in this way.
  • the shape of the groove is preferably a triangular prism. This is because the size of the injection needle or the like is not limited, it is easy to engage, and compression hemostasis can be performed efficiently.
  • FIG.1 (d) it is also preferable to set it as a mountain-valley shape as a form of a groove part. This is because the size of the injection needle or the like is not limited, it is easy to engage, and compression hemostasis can be performed efficiently. Moreover, if the shape of a groove part is a mountain-and-valley shape, it can improve also about retainability, such as a cylindrical injection needle.
  • the groove portion 14a is configured such that the groove portion at one end of the compressed hemostatic cotton is wide and the width gradually decreases toward the other end portion. . This is because the end portion of the groove is so-called tapered so that it can be more easily engaged with an injection needle or the like.
  • the groove portion 14d it is also preferable to form a blood pool portion larger than the width of the groove portion in a part of the groove portion. This is because the blood can be more difficult to leak to the outside by providing such a blood pool.
  • the groove 14e it is also preferable to make the color of the groove and other portions different from each other by coloring a part or the whole of the groove. The reason for this is to make it easier to visually recognize the groove portion by coloring in this way.
  • the durometer hardness (E standard) of compressed hemostatic cotton according to JIS K6253 is a value within the range of 20 to 80 hardness (basically there is no unit, but may be expressed as degrees or °). It is preferable that The reason for this is that by configuring in this way, it is possible to quantitatively manage the hardness of the compressed hemostatic cotton and to manufacture it stably. Further, when the hardness is less than 20 hardness, the density inside the compressed hemostatic cotton is lowered, and the compressed hemostatic cotton absorbs a large amount of blood, which may reduce the hemostatic function. In addition, the strength is reduced, and the shape changes during storage, which may make it impossible to use.
  • the durometer hardness of the compressed hemostatic cotton is more preferably in the range of 25 to 70 hardness, and further preferably in the range of 30 to 60 hardness.
  • 2nd Embodiment of this invention is a manufacturing method of the compression hemostatic cotton formed by integrally molding a fibrous material, Comprising: The process of shape
  • the manufacturing method of the compression hemostatic cotton which is 2nd Embodiment of this invention is demonstrated concretely centering on a different point from 1st Embodiment.
  • the roll-shaped molding process is a process of molding a sheet-like fibrous material into a roll having a predetermined size, as shown in FIG.
  • the method for forming the sheet-like fibrous material into a roll shape is not particularly limited, but it can be easily produced, for example, by uniformly forming a roll shape with a winding device.
  • a fibrous material 30 of a predetermined size molded into a roll is compression molded using predetermined molds 42 and 44, This is a step of forming into a predetermined shape 40.
  • the heat compression molding process can be performed by moving the predetermined mold 42 up and down in the direction of the arrow.
  • the conditions for heat compression molding are not particularly limited.
  • a mixed non-woven fabric of polyester fiber and rayon fiber is used, from the softening point (for example, 240 ° C.) of the polyester fiber. It is preferable to mold at a temperature higher than the thermal decomposition temperature of rayon fiber (about 310 ° C.). The reason for this is that by producing under such temperature conditions, the polyester fiber serves as a binder in the rayon fiber, and a compressed hemostatic cotton having both water absorption and water repellency can be efficiently produced.
  • the fibrous material after heat-molding the fibrous material, it can be cut using a cutting jig so as to be a predetermined size, or after being molded into a roll shape, it is cut into a predetermined size. It is also possible to heat compression molding.
  • the step of forming the groove part is for forming a groove part in advance when a fibrous material molded into a roll shape is compression-molded using a predetermined mold.
  • a mold 42 having a convex portion can also be used. The reason for this is that the manufacturing improves the workability and can be manufactured at a low cost.
  • a groove portion can be further formed after molding into a predetermined shape. This is because various groove shapes can be easily formed. Furthermore, a method of removing the groove part mold after compression molding the roll-like fibrous material and the predetermined groove part mold as an integral body during compression molding can also be used.
  • the compression hemostatic cotton having the groove portion can be used to easily install the compression hemostatic cotton in the puncture portion. I can do it now.
  • the needle such as the injection needle can be easily removed, and the blood can be prevented from leaking from the puncture portion.

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  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Manufacturing & Machinery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Surgery (AREA)
  • Epidemiology (AREA)
  • Materials For Medical Uses (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)

Abstract

L'invention concerne une compresse de coton hémostatique avec une capacité de mise en œuvre améliorée sans perte des effets d'astriction quand des aiguilles artério-veineuses à demeure sont utilisées dans la dialyse artificielle, l'injection, la perfusion goutte à goutte, la prise de sang, etc. et que l'aiguille, etc. est retirée du site de ponction et un procédé de production de celle-ci. La compresse de coton hémostatique et le procédé de production de celle-ci impliquent un moulage en une pièce d'une substance fibreuse. La compresse a une surface pour compresser un site d'hémostase spécifié et, formant une partie de ladite surface à aplatir ou incurver, une partie de ladite surface est pourvue d'une rainure pour engager l'aiguille ou le tube en plastique qui y est attaché.
PCT/JP2011/064383 2010-08-30 2011-06-23 Compresse de coton hémostatique et procédé de production de celle-ci Ceased WO2012029383A1 (fr)

Priority Applications (2)

Application Number Priority Date Filing Date Title
JP2012531723A JP5082027B2 (ja) 2010-08-30 2011-06-23 圧迫止血綿及びその製造方法
CN2011800413738A CN103068350A (zh) 2010-08-30 2011-06-23 压迫止血棉及其制造方法

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2010-191964 2010-08-30
JP2010191964 2010-08-30

Publications (1)

Publication Number Publication Date
WO2012029383A1 true WO2012029383A1 (fr) 2012-03-08

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PCT/JP2011/064383 Ceased WO2012029383A1 (fr) 2010-08-30 2011-06-23 Compresse de coton hémostatique et procédé de production de celle-ci

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JP (1) JP5082027B2 (fr)
CN (1) CN103068350A (fr)
WO (1) WO2012029383A1 (fr)

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH057216U (ja) * 1991-07-08 1993-02-02 富士システムズ株式会社 止血用パツト
JPH08140990A (ja) * 1994-11-21 1996-06-04 Nichiban Co Ltd 止血用具
JP2001017461A (ja) * 1999-07-09 2001-01-23 Asahi Chem Ind Co Ltd 止血用貼材
JP2001523484A (ja) * 1997-11-14 2001-11-27 ベネテック インターナショナル インコーポレイテッド 医療用ライン固定器具
JP2004181063A (ja) * 2002-12-05 2004-07-02 Nitto Denko Corp 止血用部材およびその使用方法
JP2006507047A (ja) * 2002-11-01 2006-03-02 サイオン カーディオバスキュラー インコーポレイテッド 止血パッド

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2003019159A (ja) * 2001-07-11 2003-01-21 Osaki Eisei Zairyo Kk 止血パッドとその製造法

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH057216U (ja) * 1991-07-08 1993-02-02 富士システムズ株式会社 止血用パツト
JPH08140990A (ja) * 1994-11-21 1996-06-04 Nichiban Co Ltd 止血用具
JP2001523484A (ja) * 1997-11-14 2001-11-27 ベネテック インターナショナル インコーポレイテッド 医療用ライン固定器具
JP2001017461A (ja) * 1999-07-09 2001-01-23 Asahi Chem Ind Co Ltd 止血用貼材
JP2006507047A (ja) * 2002-11-01 2006-03-02 サイオン カーディオバスキュラー インコーポレイテッド 止血パッド
JP2004181063A (ja) * 2002-12-05 2004-07-02 Nitto Denko Corp 止血用部材およびその使用方法

Also Published As

Publication number Publication date
CN103068350A (zh) 2013-04-24
JP5082027B2 (ja) 2012-11-28
JPWO2012029383A1 (ja) 2013-10-28

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