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WO2012009711A3 - Détection de rétrovirus - Google Patents

Détection de rétrovirus Download PDF

Info

Publication number
WO2012009711A3
WO2012009711A3 PCT/US2011/044296 US2011044296W WO2012009711A3 WO 2012009711 A3 WO2012009711 A3 WO 2012009711A3 US 2011044296 W US2011044296 W US 2011044296W WO 2012009711 A3 WO2012009711 A3 WO 2012009711A3
Authority
WO
WIPO (PCT)
Prior art keywords
retrovirus detection
retrovirus
detection
contamination
methods
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/US2011/044296
Other languages
English (en)
Other versions
WO2012009711A2 (fr
Inventor
Douglas J. Jolly
Omar Perez
Amy Lin
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Forte Biosciences Inc
Original Assignee
Tocagen Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Tocagen Inc filed Critical Tocagen Inc
Priority to CA2803011A priority Critical patent/CA2803011C/fr
Priority to US13/810,403 priority patent/US9663834B2/en
Priority to EP11807616.5A priority patent/EP2580325A4/fr
Priority to CN2011800446801A priority patent/CN103140581A/zh
Publication of WO2012009711A2 publication Critical patent/WO2012009711A2/fr
Publication of WO2012009711A3 publication Critical patent/WO2012009711A3/fr
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/70Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
    • C12Q1/701Specific hybridization probes
    • C12Q1/702Specific hybridization probes for retroviruses
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/70Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
    • C12Q1/701Specific hybridization probes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2740/00Reverse transcribing RNA viruses
    • C12N2740/00011Details
    • C12N2740/10011Retroviridae
    • C12N2740/13011Gammaretrovirus, e.g. murine leukeamia virus
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2799/00Uses of viruses
    • C12N2799/02Uses of viruses as vector
    • C12N2799/021Uses of viruses as vector for the expression of a heterologous nucleic acid
    • C12N2799/027Uses of viruses as vector for the expression of a heterologous nucleic acid where the vector is derived from a retrovirus

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Immunology (AREA)
  • Wood Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Virology (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

L'invention concerne des procédés et des compositions utiles pour détecter une infection ou une contamination virale dans un échantillon biologique.
PCT/US2011/044296 2010-07-16 2011-07-16 Détection de rétrovirus Ceased WO2012009711A2 (fr)

Priority Applications (4)

Application Number Priority Date Filing Date Title
CA2803011A CA2803011C (fr) 2010-07-16 2011-07-16 Detection de retrovirus
US13/810,403 US9663834B2 (en) 2010-07-16 2011-07-16 Retrovirus detection
EP11807616.5A EP2580325A4 (fr) 2010-07-16 2011-07-16 Détection de rétrovirus
CN2011800446801A CN103140581A (zh) 2010-07-16 2011-07-16 逆转录病毒检测

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US36529710P 2010-07-16 2010-07-16
US61/365,297 2010-07-16
US38694110P 2010-09-27 2010-09-27
US61/386,941 2010-09-27
US39136010P 2010-10-08 2010-10-08
US61/391,360 2010-10-08

Publications (2)

Publication Number Publication Date
WO2012009711A2 WO2012009711A2 (fr) 2012-01-19
WO2012009711A3 true WO2012009711A3 (fr) 2012-05-31

Family

ID=45470115

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2011/044296 Ceased WO2012009711A2 (fr) 2010-07-16 2011-07-16 Détection de rétrovirus

Country Status (6)

Country Link
US (1) US9663834B2 (fr)
EP (2) EP2580325A4 (fr)
CN (1) CN103140581A (fr)
CA (1) CA2803011C (fr)
ES (1) ES2655500T3 (fr)
WO (1) WO2012009711A2 (fr)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107129971A (zh) 2009-06-17 2017-09-05 托卡根公司 复制型逆转录病毒载体的生产细胞
EP3286335A4 (fr) * 2015-04-24 2018-10-17 The Johns Hopkins University Compositions et procédés se rapportant à la caractérisation de réservoirs proviraux
CA3179579A1 (fr) * 2020-04-06 2021-10-14 Octant, Inc. Test de diagnostic d'agent pathogene
CN112011649B (zh) * 2020-10-29 2021-01-15 苏州良辰生物医药科技有限公司 一种用于检测异嗜性小鼠白血病病毒的引物探针、试剂盒及应用
CN113444841B (zh) * 2021-08-23 2022-05-24 山东省滨州畜牧兽医研究院 一种狐狸逆转录病毒SYBR Green Ⅰ荧光RT-PCR试剂盒及使用方法
CN113444842B (zh) * 2021-08-23 2022-08-02 山东省滨州畜牧兽医研究院 一种用于狐狸逆转录病毒检测的特异引物组及pcr检测试剂盒的应用

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2006110589A2 (fr) * 2005-04-07 2006-10-19 The Cleveland Clinic Foundation Gammaretrovirus associe au cancer
US20100167268A1 (en) * 2009-07-15 2010-07-01 Mikovits Judy A Seroconversion assays for detecting xenotropic murine leukemia virus-related virus
WO2010075414A2 (fr) * 2008-12-23 2010-07-01 The Cleveland Clinic Foundation Procédé de détection du xmrv

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Publication number Priority date Publication date Assignee Title
US4458066A (en) 1980-02-29 1984-07-03 University Patents, Inc. Process for preparing polynucleotides
US4965188A (en) 1986-08-22 1990-10-23 Cetus Corporation Process for amplifying, detecting, and/or cloning nucleic acid sequences using a thermostable enzyme
ATE92538T1 (de) 1988-01-21 1993-08-15 Genentech Inc Verstaerkung und nachweis von nukleinsaeuresequenzen.
CA1340807C (fr) 1988-02-24 1999-11-02 Lawrence T. Malek Procede d'amplification d'une sequence d'acide nucleique
US5130238A (en) 1988-06-24 1992-07-14 Cangene Corporation Enhanced nucleic acid amplification process
WO1990001069A1 (fr) 1988-07-20 1990-02-08 Segev Diagnostics, Inc. Procede d'amplification et de detection de sequences d'acide nucleique
US5143854A (en) 1989-06-07 1992-09-01 Affymax Technologies N.V. Large scale photolithographic solid phase synthesis of polypeptides and receptor binding screening thereof
DK0562025T3 (da) 1990-12-06 2001-06-18 Affymetrix Inc Forbindelser og deres anvendelse i en binær syntesestrategi
US5169766A (en) 1991-06-14 1992-12-08 Life Technologies, Inc. Amplification of nucleic acid molecules
US5412087A (en) 1992-04-24 1995-05-02 Affymax Technologies N.V. Spatially-addressable immobilization of oligonucleotides and other biological polymers on surfaces
US6015686A (en) * 1993-09-15 2000-01-18 Chiron Viagene, Inc. Eukaryotic layered vector initiation systems
EP0730663B1 (fr) 1993-10-26 2003-09-24 Affymetrix, Inc. Reseaux de sondes d'acide nucleique sur des microplaquettes biologiques
ATE232880T1 (de) 1996-11-18 2003-03-15 Takeshi Imanishi Neue nucleotidanaloga
JP3756313B2 (ja) 1997-03-07 2006-03-15 武 今西 新規ビシクロヌクレオシド及びオリゴヌクレオチド類縁体
CA2303299C (fr) 1997-09-12 2016-02-23 Exiqon A/S Analogues d'oligonucleotides
US7419964B2 (en) * 1999-09-16 2008-09-02 Cytogenix, Inc. Treatment of HSV-related pathologies using ssDNA
WO2006110489A2 (fr) 2005-04-08 2006-10-19 University Of Utah Research Foundation Fabrication rapide de prototype de microstructures au moyen d'un traceurs de decoupe
WO2007130519A2 (fr) * 2006-05-02 2007-11-15 Government Of The Usa, As Represented By The Secretary, Department Of Health And Human Services Microréseau d'acide nucléique viral et procédé d'utilisation
KR101390967B1 (ko) * 2006-10-10 2014-05-14 주식회사 바이로메드 안전성이 향상된 레트로바이러스 벡터
EP2344648B1 (fr) 2008-09-26 2018-11-14 Tocagen Inc. Vecteurs recombinants
CN107129971A (zh) 2009-06-17 2017-09-05 托卡根公司 复制型逆转录病毒载体的生产细胞
ES2660755T3 (es) 2010-10-31 2018-03-26 Tocagen Inc. Ensayos de antisueros para virus relacionados con VLM en seres humanos y otros mamíferos

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2006110589A2 (fr) * 2005-04-07 2006-10-19 The Cleveland Clinic Foundation Gammaretrovirus associe au cancer
WO2010075414A2 (fr) * 2008-12-23 2010-07-01 The Cleveland Clinic Foundation Procédé de détection du xmrv
US20100167268A1 (en) * 2009-07-15 2010-07-01 Mikovits Judy A Seroconversion assays for detecting xenotropic murine leukemia virus-related virus

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
ERLWEIN 0. ET AL.: "Failure to detect the novel retrovirus XMRV in chronic fatigue syndrome.", PLOS ONE, vol. 5, no. 1, 6 January 2010 (2010-01-06), pages E8519, XP055072557 *
URISMAN A. ET AL.: "Identification of a novel Gammaretrovirus in prostate tumors of patients homozygous for R462Q RNASEL variant.", PLOS PATHOGENS, vol. 2, no. 3, March 2006 (2006-03-01), pages E25, XP002669943 *

Also Published As

Publication number Publication date
EP2580325A4 (fr) 2013-11-20
EP2580325A2 (fr) 2013-04-17
US20130266931A1 (en) 2013-10-10
US9663834B2 (en) 2017-05-30
ES2655500T3 (es) 2018-02-20
CA2803011A1 (fr) 2012-01-19
CA2803011C (fr) 2019-12-03
WO2012009711A2 (fr) 2012-01-19
CN103140581A (zh) 2013-06-05
EP2913402B1 (fr) 2017-10-18
EP2913402A1 (fr) 2015-09-02

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