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WO2012079076A3 - Methods and systems for distributing a plurality of particles within a viscoelastic specimen - Google Patents

Methods and systems for distributing a plurality of particles within a viscoelastic specimen Download PDF

Info

Publication number
WO2012079076A3
WO2012079076A3 PCT/US2011/064412 US2011064412W WO2012079076A3 WO 2012079076 A3 WO2012079076 A3 WO 2012079076A3 US 2011064412 W US2011064412 W US 2011064412W WO 2012079076 A3 WO2012079076 A3 WO 2012079076A3
Authority
WO
WIPO (PCT)
Prior art keywords
viscoelastic
specimen
particles
distributing
systems
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/US2011/064412
Other languages
French (fr)
Other versions
WO2012079076A2 (en
Inventor
Richard Superfine
Jeremy Cribb
Stephen Norris
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of North Carolina at Chapel Hill
Original Assignee
University of North Carolina at Chapel Hill
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University of North Carolina at Chapel Hill filed Critical University of North Carolina at Chapel Hill
Publication of WO2012079076A2 publication Critical patent/WO2012079076A2/en
Publication of WO2012079076A3 publication Critical patent/WO2012079076A3/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/38—Diluting, dispersing or mixing samples
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N11/00—Investigating flow properties of materials, e.g. viscosity, plasticity; Analysing materials by determining flow properties
    • G01N11/10—Investigating flow properties of materials, e.g. viscosity, plasticity; Analysing materials by determining flow properties by moving a body within the material
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N11/00—Investigating flow properties of materials, e.g. viscosity, plasticity; Analysing materials by determining flow properties
    • G01N11/10—Investigating flow properties of materials, e.g. viscosity, plasticity; Analysing materials by determining flow properties by moving a body within the material
    • G01N11/14—Investigating flow properties of materials, e.g. viscosity, plasticity; Analysing materials by determining flow properties by moving a body within the material by using rotary bodies, e.g. vane
    • G01N2011/147—Magnetic coupling

Landscapes

  • Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Sampling And Sample Adjustment (AREA)

Abstract

Methods and systems for distributing a plurality of particles within a viscoelastic specimen are disclosed. According to one example, a method includes drawing, into a doping device, a particle solution that includes a plurality of particles suspended in a buffer fluid. The method further includes adhering the particles to a surface of the doping device by evaporating the buffer fluid from the particle solution and drawing, into the doping device, a viscoelastic specimen that causes the particles to dislodge from the surface of the doping device and become suspended within the viscoelastic specimen. The method also includes measuring the movement of the particles suspended within the viscoelastic specimen to determine at least one rheological property of the viscoelastic specimen.
PCT/US2011/064412 2010-12-10 2011-12-12 Methods and systems for distributing a plurality of particles within a viscoelastic specimen Ceased WO2012079076A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US42197310P 2010-12-10 2010-12-10
US61/421,973 2010-12-10

Publications (2)

Publication Number Publication Date
WO2012079076A2 WO2012079076A2 (en) 2012-06-14
WO2012079076A3 true WO2012079076A3 (en) 2012-11-22

Family

ID=46207788

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2011/064412 Ceased WO2012079076A2 (en) 2010-12-10 2011-12-12 Methods and systems for distributing a plurality of particles within a viscoelastic specimen

Country Status (1)

Country Link
WO (1) WO2012079076A2 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB201216362D0 (en) * 2012-09-13 2012-10-31 Reading Michael Apparatus and method for the versatile thermal characterisation of materials
EP2926115B1 (en) 2012-11-30 2021-05-26 The University of North Carolina At Chapel Hill Methods and systems for determining physical properties of a specimen in a portable point of care diagnostic device

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5627037A (en) * 1990-08-07 1997-05-06 Becton Dickinson And Company One step method for detection and enumeration of absolute counts of one more cell populations in a sample
EP1016460A2 (en) * 1998-11-10 2000-07-05 Becton Dickinson and Company Method for coating a blood collection device
US6958816B1 (en) * 2001-10-05 2005-10-25 Research Foundation Of The University Of Central Florida Microrheology methods and systems using low-coherence dynamic light scattering
US20090253215A1 (en) * 2004-12-23 2009-10-08 Koninklijke Philips Electronics, N.V. Method for controlling the flow of liquids containing biological material by inducing electro- or magneto-rheological effect

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5627037A (en) * 1990-08-07 1997-05-06 Becton Dickinson And Company One step method for detection and enumeration of absolute counts of one more cell populations in a sample
EP1016460A2 (en) * 1998-11-10 2000-07-05 Becton Dickinson and Company Method for coating a blood collection device
US6958816B1 (en) * 2001-10-05 2005-10-25 Research Foundation Of The University Of Central Florida Microrheology methods and systems using low-coherence dynamic light scattering
US20090253215A1 (en) * 2004-12-23 2009-10-08 Koninklijke Philips Electronics, N.V. Method for controlling the flow of liquids containing biological material by inducing electro- or magneto-rheological effect

Also Published As

Publication number Publication date
WO2012079076A2 (en) 2012-06-14

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