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WO2012067437A3 - 간 절제를 위한 간 부피 증가용 조성물 - Google Patents

간 절제를 위한 간 부피 증가용 조성물 Download PDF

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Publication number
WO2012067437A3
WO2012067437A3 PCT/KR2011/008778 KR2011008778W WO2012067437A3 WO 2012067437 A3 WO2012067437 A3 WO 2012067437A3 KR 2011008778 W KR2011008778 W KR 2011008778W WO 2012067437 A3 WO2012067437 A3 WO 2012067437A3
Authority
WO
WIPO (PCT)
Prior art keywords
liver
resection
volume
increasing
liver resection
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/KR2011/008778
Other languages
English (en)
French (fr)
Other versions
WO2012067437A2 (ko
Inventor
유경하
한호성
서주영
안근수
우소연
조경아
주선영
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ewha Womans University
Original Assignee
Ewha Womans University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ewha Womans University filed Critical Ewha Womans University
Publication of WO2012067437A2 publication Critical patent/WO2012067437A2/ko
Publication of WO2012067437A3 publication Critical patent/WO2012067437A3/ko
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/193—Colony stimulating factors [CSF]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/28—Bone marrow; Haematopoietic stem cells; Mesenchymal stem cells of any origin, e.g. adipose-derived stem cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Developmental Biology & Embryology (AREA)
  • Chemical & Material Sciences (AREA)
  • Cell Biology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Zoology (AREA)
  • Epidemiology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Virology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Hematology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

본 발명은 골수세포 유래 단핵세포, 골수세포 유래 조혈모세포, 및 G-CSF로 구성된 군으로부터 선택되는 1종 이상을 사용하여, 간 절제가 필요한 대상의 간 절제 방법, 간 절제를 위한 간 부피 증가용 약학 조성물, 간 부피 증가제를 포함하는 간 절제용 수술 키트, 및 상기 조성물의 간 절제를 위한 간 부피 증가 용도에 관한 것이다. 본 발명에 의하면, 간의 손상이 심하여 간 절제술이 불가능한 대상의 간의 기능 호전 및 부피를 증가시켜, 광범위한 간 절제술을 가능하게 함으로써, 여러 간질환을 치료할 수 있다.
PCT/KR2011/008778 2010-11-16 2011-11-16 간 절제를 위한 간 부피 증가용 조성물 Ceased WO2012067437A2 (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR20100114148 2010-11-16
KR10-2010-0114148 2010-11-16

Publications (2)

Publication Number Publication Date
WO2012067437A2 WO2012067437A2 (ko) 2012-05-24
WO2012067437A3 true WO2012067437A3 (ko) 2012-08-30

Family

ID=46084525

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/KR2011/008778 Ceased WO2012067437A2 (ko) 2010-11-16 2011-11-16 간 절제를 위한 간 부피 증가용 조성물

Country Status (2)

Country Link
KR (1) KR20120052895A (ko)
WO (1) WO2012067437A2 (ko)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
USD784972S1 (en) 2014-10-01 2017-04-25 Samsung Electronics Co., Ltd. Portable electronic device
USD779450S1 (en) 2014-10-01 2017-02-21 Samsung Electronics Co., Ltd. Portable electronic device
USD781275S1 (en) 2014-10-01 2017-03-14 Samsung Electronics Co., Ltd. Portable electronic device
USD803818S1 (en) 2014-10-01 2017-11-28 Samsung Electronics Co., Ltd. Portable electronic device
USD779449S1 (en) 2014-10-01 2017-02-21 Samsung Electronics Co., Ltd. Portable electronic device
USD795855S1 (en) 2014-10-01 2017-08-29 Samsung Electronics Co., Ltd. Portable electronic device
USD797713S1 (en) 2014-10-01 2017-09-19 Samsung Electronics Co., Ltd. Portable electronic device
USD785586S1 (en) 2014-10-01 2017-05-02 Samsung Electronics Co., Ltd. Portable electronic device

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
JAN SCHULTE AM ESCH II ET AL.: "Portal application of autologous CD133+ bone marrow cells to the liver: A novel concept to support hepatic regeneration", STEM CELLS, vol. 23, no. 4, 2005, pages 463 - 470 *
PING JIN ET AL.: "Differentiation of two types of mobilized peripheral blood stem cells by microRNA and cDNA expression analysis", JOURNAL OF TRANSLATIONAL MEDICINE, vol. 6, no. 39, 2008 *
SILVIA GAIA ET AL.: "Feasibility and safety of G-CSF administration to induce bone marrow-derived cells mobilization in patients with end stage liver disease", JOURNAL OF HEPATOLOGY, vol. 45, no. 1, 2006, pages 13 - 19 *
Y. N. KALLIS ET AL.: "Bone marrow stem cells and liver disease", GUT, vol. 56, no. 5, 2007, pages 716 - 724 *

Also Published As

Publication number Publication date
KR20120052895A (ko) 2012-05-24
WO2012067437A2 (ko) 2012-05-24

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