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WO2011107614A3 - Méthode d'évaluation du potentiel sensibilisant et/ou irritant d'un composé test - Google Patents

Méthode d'évaluation du potentiel sensibilisant et/ou irritant d'un composé test Download PDF

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Publication number
WO2011107614A3
WO2011107614A3 PCT/EP2011/053399 EP2011053399W WO2011107614A3 WO 2011107614 A3 WO2011107614 A3 WO 2011107614A3 EP 2011053399 W EP2011053399 W EP 2011053399W WO 2011107614 A3 WO2011107614 A3 WO 2011107614A3
Authority
WO
WIPO (PCT)
Prior art keywords
sensitising
evaluating
test compound
irritant potential
irritant
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/EP2011/053399
Other languages
English (en)
Other versions
WO2011107614A2 (fr
Inventor
Hervé GROUX
Françoise Cottrez
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
IMMUNOSEARCH
Original Assignee
IMMUNOSEARCH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by IMMUNOSEARCH filed Critical IMMUNOSEARCH
Publication of WO2011107614A2 publication Critical patent/WO2011107614A2/fr
Publication of WO2011107614A3 publication Critical patent/WO2011107614A3/fr
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/136—Screening for pharmacological compounds
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/158—Expression markers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Analytical Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Investigating Or Analyzing Non-Biological Materials By The Use Of Chemical Means (AREA)
  • Testing Resistance To Weather, Investigating Materials By Mechanical Methods (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

L'invention se rapporte à une méthode d'évaluation du potentiel sensibilisant et/ou irritant d'un composé test et à une trousse pour la mise en œuvre de ladite méthode.
PCT/EP2011/053399 2010-03-05 2011-03-07 Méthode d'évaluation du potentiel sensibilisant et/ou irritant d'un composé test Ceased WO2011107614A2 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR1051635 2010-03-05
FR1051635A FR2957088A1 (fr) 2010-03-05 2010-03-05 Methode d'evaluation du potentiel sensibilisant et/ou irritant d'un compose test

Publications (2)

Publication Number Publication Date
WO2011107614A2 WO2011107614A2 (fr) 2011-09-09
WO2011107614A3 true WO2011107614A3 (fr) 2011-12-01

Family

ID=42797538

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2011/053399 Ceased WO2011107614A2 (fr) 2010-03-05 2011-03-07 Méthode d'évaluation du potentiel sensibilisant et/ou irritant d'un composé test

Country Status (2)

Country Link
FR (1) FR2957088A1 (fr)
WO (1) WO2011107614A2 (fr)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB201700138D0 (en) 2017-01-05 2017-02-22 Senzagen Ab Analytical methods and arrays for use in the same

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002070729A2 (fr) * 2001-03-02 2002-09-12 Stratatech Corporation Substituts de peau ameliores et utilisations correspondantes
US20070059711A1 (en) * 2004-07-30 2007-03-15 Andrzej Slominski Microarray for evaluation of stress-related genes in skin
WO2007090575A1 (fr) * 2006-02-10 2007-08-16 Phenion Gmbh & Co. Kg Modèle de peau avec cellules dendritiques
WO2008008500A2 (fr) * 2006-07-13 2008-01-17 Yale University Procédés pronostiques du cancer à partir de la localisation subcellulaire de biomarqueurs
WO2008037806A2 (fr) * 2006-09-29 2008-04-03 Vlaamse Instelling Voor Technologisch Onderzoek (Vito) Méthode de détermination du pouvoir allergique d'un composé

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4683202A (en) 1985-03-28 1987-07-28 Cetus Corporation Process for amplifying nucleic acid sequences
US5854033A (en) 1995-11-21 1998-12-29 Yale University Rolling circle replication reporter systems

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002070729A2 (fr) * 2001-03-02 2002-09-12 Stratatech Corporation Substituts de peau ameliores et utilisations correspondantes
US20070059711A1 (en) * 2004-07-30 2007-03-15 Andrzej Slominski Microarray for evaluation of stress-related genes in skin
WO2007090575A1 (fr) * 2006-02-10 2007-08-16 Phenion Gmbh & Co. Kg Modèle de peau avec cellules dendritiques
WO2008008500A2 (fr) * 2006-07-13 2008-01-17 Yale University Procédés pronostiques du cancer à partir de la localisation subcellulaire de biomarqueurs
WO2008037806A2 (fr) * 2006-09-29 2008-04-03 Vlaamse Instelling Voor Technologisch Onderzoek (Vito) Méthode de détermination du pouvoir allergique d'un composé

Non-Patent Citations (10)

* Cited by examiner, † Cited by third party
Title
BORLON ET AL: "The usefulness of toxicogenomics for predicting acute skin irritation on in vitro reconstructed human epidermis", TOXICOLOGY, LIMERICK, IR LNKD- DOI:10.1016/J.TOX.2007.08.096, vol. 241, no. 3, 23 October 2007 (2007-10-23), pages 157 - 166, XP022310517, ISSN: 0300-483X *
FLETCHER S T ET AL: "Gene expression analysis of EpiDermTM following exposure to SLS using cDNA microarrays", TOXICOLOGY IN VITRO, vol. 15, no. 4-5, August 2001 (2001-08-01), pages 393 - 398, XP007915270, ISSN: 0887-2333 *
KU H O ET AL: "Gene expression profiles and pathways in skin inflammation induced by three different sensitizers and an irritant", TOXICOLOGY LETTERS, ELSEVIER BIOMEDICAL PRESS, AMSTERDAM, NL, vol. 190, no. 2, 28 October 2009 (2009-10-28), pages 231 - 237, XP026715163, ISSN: 0378-4274, [retrieved on 20090730], DOI: DOI:10.1016/J.TOXLET.2009.07.022 *
KU H O ET AL: "Intracellular expression of cytokines and granzyme B in auricular lymph nodes draining skin exposed to irritants and sensitizers", TOXICOLOGY, LIMERICK, IR, vol. 250, no. 2-3, 4 September 2008 (2008-09-04), pages 116 - 123, XP024100640, ISSN: 0300-483X, [retrieved on 20080704], DOI: DOI:10.1016/J.TOX.2008.06.011 *
LAOUINI ET AL: "COX-2 inhibition enhances the TH2 immune response to epicutaneous sensitization", JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, MOSBY, INC, US LNKD- DOI:10.1016/J.JACI.2005.03.042, vol. 116, no. 2, 1 August 2005 (2005-08-01), pages 390 - 396, XP005002828, ISSN: 0091-6749 *
LEE J ET AL: "4-1BB promotes long-term survival in skin allografts treated with anti-CD45RB and anti-CD40L monoclonal antibodies", TRANSPLANTATION PROCEEDINGS, ELSEVIER INC, ORLANDO, FL; US LNKD- DOI:10.1016/J.TRANSPROCEED.2005.01.016, vol. 37, no. 1, 1 January 2005 (2005-01-01), pages 123 - 125, XP004819875, ISSN: 0041-1345 *
MELLER ET AL: "Chemokine responses distinguish chemical-induced allergic from irritant skin inflammation: Memory T cells make the difference", JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, MOSBY, INC, US, vol. 119, no. 6, 6 June 2007 (2007-06-06), pages 1470 - 1480, XP022096903, ISSN: 0091-6749, DOI: DOI:10.1016/J.JACI.2006.12.654 *
NIWA MAKOTO ET AL: "Evaluation of the Skin Irritation Using a DNA Microarray on a Reconstructed Human Epidermal Model", BIOLOGICAL & PHARMACEUTICAL BULLETIN, vol. 32, no. 2, February 2009 (2009-02-01), pages 203 - 208, XP002603918, ISSN: 0918-6158 *
PISARCHIK ALEXANDER ET AL: "A novel microarray to evaluate stress-related genes in skin: effect of ultraviolet light radiation.", GENE 27 OCT 2004 LNKD- PUBMED:15474302, vol. 341, 27 October 2004 (2004-10-27), pages 199 - 207, XP002634146, ISSN: 0378-1119 *
S. SZAMEIT ET AL: "Gene expression studies in cultured dendritic cells: new indicators for the discrimination of skin sensitizers and irritants in vitro", CLINICAL & EXPERIMENTAL ALLERGY, vol. 39, no. 6, 1 June 2009 (2009-06-01), pages 856 - 868, XP055002859, ISSN: 0954-7894, DOI: 10.1111/j.1365-2222.2009.03222.x *

Also Published As

Publication number Publication date
FR2957088A1 (fr) 2011-09-09
WO2011107614A2 (fr) 2011-09-09

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