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WO2011152193A1 - Urine analyzer - Google Patents

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Publication number
WO2011152193A1
WO2011152193A1 PCT/JP2011/061187 JP2011061187W WO2011152193A1 WO 2011152193 A1 WO2011152193 A1 WO 2011152193A1 JP 2011061187 W JP2011061187 W JP 2011061187W WO 2011152193 A1 WO2011152193 A1 WO 2011152193A1
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WIPO (PCT)
Prior art keywords
urine
measurement unit
heater
housing
qualitative measurement
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PCT/JP2011/061187
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French (fr)
Japanese (ja)
Inventor
浩司 藤本
紀明 古里
雄太 岡村
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Arkray Inc
Sysmex Corp
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Arkray Inc
Sysmex Corp
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Publication of WO2011152193A1 publication Critical patent/WO2011152193A1/en
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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483—Physical analysis of biological material
    • G01N33/487—Physical analysis of biological material of liquid biological material
    • G01N33/493—Physical analysis of biological material of liquid biological material urine

Definitions

  • the present invention relates to a urine test apparatus for performing a urine qualitative test and a urine sediment test.
  • the urinalysis is highly useful for judging the possibility of various diseases because it is non-invasive and the variety of information available.
  • urine qualitative testing that measures the concentration of components such as protein, glucose, and bilirubin, and optical systems such as red blood cells, white blood cells, and epithelial cells are used for imaging and flow cytometer methods.
  • a urine sediment test is known.
  • the urine sediment test is generally used to obtain additional information when a specific component amount shows an abnormal value in the urine qualitative test. Therefore, conventionally, urine sediment examination is performed after urine qualitative examination using a urine qualitative examination apparatus, and after re-collecting urine of a subject who is judged to be necessary for urine sediment examination based on the result. It was common to use.
  • the present inventors In parallel with development aimed at realizing a urine qualitative test and a urine sediment test in a single system using urine samples collected at a time, the present inventors have conducted urine qualitative measurements necessary for urine qualitative tests. And the urine sediment measurement unit necessary for urinary sediment examination are designed as an integrated device in a compact design. In order to make the apparatus compact, it is necessary to arrange each component so as not to create as much useless space as possible. However, in the process of devising such an arrangement, the present inventors faced the following problems. In the analysis of urine sediment, for example, when a minute measurement object is measured with a high-precision optical system, the measurement may be performed in a constant temperature environment in order to minimize distortion due to temperature and change in characteristics.
  • the constant temperature environment is set to a temperature higher than 30 ° C. because the control is easier when the temperature is higher than the outside air temperature.
  • the reaction temperature needs to be constant at a certain temperature, and is set to 37 ° C., for example.
  • the periphery of the reaction part must always be maintained at 35 ° C. to 40 ° C., particularly preferably around 37 ° C.
  • the heat generated by the heater for maintaining the temperature adversely affects the examination area of the urine qualitative examination.
  • the present invention provides a device including a urine sediment measurement unit including a heater for heating a urine sample and a urine qualitative measurement unit, and is capable of increasing the temperature in the examination region of the urine qualitative test while making the device compact. It is an object of the present invention to provide a technology for reducing the volume.
  • the present invention for solving the above problems is a urinalysis apparatus comprising a urine qualitative measurement unit that performs measurements necessary for a urine qualitative test, and a urine sediment measurement unit that performs measurements necessary for a urine sediment test.
  • the sediment measuring unit includes a heater for heating the urine sample, and the heater is disposed above the urine qualitative measuring unit (hereinafter referred to as “the urine testing device of the present invention”). "). By disposing the heater of the urine sediment measurement unit above the urine qualitative measurement unit, heat conduction from the heater to the urine qualitative measurement unit can be suppressed.
  • the heater of the urine sediment measurement unit is disposed obliquely above the urine qualitative measurement unit. That is, it is preferable that the heater and the urine qualitative measurement unit are in a positional relationship shifted in both the vertical direction and the horizontal direction. By disposing the heater obliquely above the urine qualitative measurement unit, heat conduction from the heater to the urine qualitative measurement unit can be further suppressed.
  • the apparatus includes an intake port and an exhaust port for exchanging air around the urine qualitative measurement unit and air outside the device, and the exhaust port includes the urine It arrange
  • an air flow path communicating from the intake port to the exhaust port is formed between the heater of the urine sediment measurement unit and the urine qualitative measurement unit. That is, by forming an air flow path between the heater of the urine sediment measurement unit and the urine qualitative measurement unit, an air barrier can be formed between them, and at the same time, the heat from the heater is qualitatively urine. The heat can be exhausted out of the device before it is conducted to the measuring section.
  • the urine test apparatus includes a first casing in which the urine qualitative measurement unit is accommodated, and a second casing in which the urine sediment measurement unit is accommodated.
  • the exhaust port is provided in a position close to the second housing of the first housing.
  • An intake port and an exhaust port are provided in the first casing, and the exhaust port is provided at a position close to the second casing of the first casing, so that the intake port of the first casing in which the urine qualitative measurement unit is accommodated is changed to the exhaust port.
  • the second housing in which the urine sediment measurement unit is accommodated is located downstream (exhaust port side) of the air flow path generated toward the air flow, the heat generated by the heater of the urine sediment measurement unit is It can be discharged out of the apparatus by the air flowing through the air flow path before being conducted to the urine qualitative measurement unit in the 1-body body.
  • region is provided between the 1st housing and the 2nd housing.
  • the first casing includes a protrusion that protrudes in the horizontal direction and the upper surface is exposed, and the urine qualitative measurement unit is provided in the protrusion, and the urine sediment measurement unit includes:
  • the heater is provided in the second casing.
  • the urine qualitative measurement unit includes a test paper inlet for introducing a test paper that reacts with a specific component in the urine sample and colors.
  • the paper slot is provided on the upper surface of the protruding portion.
  • the urinalysis apparatus of the present invention makes it possible to reduce the heat conduction to the urine qualitative measurement part of the heater of the urine sediment measurement part while making the whole apparatus compact.
  • a urinalysis apparatus 1 shown in FIG. 1 includes a first casing A in which a urine qualitative measurement unit 2 is stored, a second casing B in which a urine sediment measurement unit 3 is stored, a urine collection tube that stores a urine sample, a nozzle 51, and A sample supply unit C that supplies the sample to the collection position 52 is provided.
  • the first housing A has a convex shape when viewed from the front, and the second housing B has an inverted L shape when viewed from the front.
  • the second housing B is connected to the first housing A so as to fill the upper space on the left side of the first housing A.
  • casing A has protrusion part A1 which protruded in the horizontal direction and the upper surface was exposed.
  • a gap g which is a heat insulating region, is provided between the first housing A and the second housing B. Thereby, heat conduction from the heater 31 to be described later to the urine qualitative measurement unit 2 can be efficiently prevented.
  • the shape of the casing is not particularly limited, and can be changed as appropriate from the viewpoint of space saving. Further, the urinalysis apparatus of the present invention does not necessarily need to be partitioned by two housings, and may be partitioned by a plurality of housings. You may partition using a heat insulating material.
  • the first housing A includes the urine qualitative measurement unit 2, an intake port 41, an exhaust port 42, and a nozzle 51.
  • the nozzle 51 collects a urine sample from a urine collection tube on the sample supply unit C and transports the urine sample to a test paper reaction unit (not shown) of the urine qualitative measurement unit 2 in order to perform necessary measurements. To spot.
  • the urine qualitative measurement unit 2 is a part that optically detects the coloration using a test paper that reacts with a specific component in the urine sample and develops color, and acquires data on the component in the urine sample. Yes, provided in the protrusion A1 of the first housing A.
  • the urine qualitative measurement unit 2 is disposed at a position close to the outside of the apparatus, so that the urine qualitative measurement unit 2 can be efficiently prevented from being heated.
  • the urine qualitative measurement unit 2 is a test paper storage tank 21 for storing test paper, a test paper reaction unit (not shown) for spotting and reacting a sample sucked by a nozzle, and a reflection for detecting the color of the test paper
  • An optical system (not shown), a control unit (not shown) that processes and analyzes the detection result, generates output data, and controls the drive system of the apparatus are included.
  • test paper storage tank 21 is provided with a test paper input port 22 for inputting test paper, and the test paper input port 22 is provided on the upper surface of the protruding portion A1.
  • the test paper can be easily loaded from outside the apparatus.
  • the urine qualitative measurement part 2 will be arrange
  • the intake port 41 is provided on the right side surface of the protruding portion A1 of the first housing A, and the exhaust port 42 is provided on the convex upper back surface of the first housing A. Further, the exhaust port 42 includes a fan 43 for exhausting air out of the apparatus. As will be apparent to those skilled in the art, a mechanism other than a fan can be used to send the air sucked from the intake port to the exhaust port. Further, the position of the fan when using the fan is not particularly limited as long as the air can be discharged from the exhaust port. In this embodiment, since the air flow path p formed by the intake port 41 and the exhaust port 42 is located around the urine qualitative measurement unit 2, the air around the urine qualitative measurement unit is efficiently exchanged with the air outside the device. Can be exchanged.
  • the exhaust port 42 is located above the intake port 41, the heated air can be discharged efficiently.
  • the number of intake ports and exhaust ports is one, but a plurality of them may be provided. Further, the positions of the intake port and the exhaust port are not particularly limited as long as the air around the urine qualitative measurement unit can be discharged.
  • the second housing B includes the urine sediment measurement unit 3 and the nozzle 52.
  • the nozzle 52 collects a urine sample from a urine collection tube on the sample supply unit C, and supplies the sample to a sample tank (not shown) of the urine sediment measurement unit 3 in order to perform necessary measurements.
  • the nozzle 51 described above may be used as a mechanism for supplying the urine sample to the urine sediment measuring unit 3 by appropriately changing the configuration of the supply pipe connected to the nozzle 51 provided in the first casing A described above. Is possible.
  • the urine sediment measurement unit 3 acquires an image or optical feature amount of a solid component in the urine sample, and analyzes the solid component from individual data.
  • the urine sediment measurement unit 3 maintains a sample tank for storing a urine sample, a urine sample in the sample tank, a reaction unit for staining or denaturing the urine sample, and an optical system (such as a flow cytometer) at a temperature of about 37 ° C. Temperature sensor and temperature control unit (both not shown), an electric heater 31 for heating the urine sample, an optical system (such as a flow cytometer) for imaging the solid component of the urine sample (not shown), an image And a control unit (not shown) that processes and analyzes the optical feature quantity, generates output data, and controls the drive system of the apparatus.
  • These configurations are usually provided in a conventional apparatus for performing analysis for urinary sediment examination, and those configurations can be understood by those skilled in the art without specific description.
  • the air flow path p communicating from the intake port 41 to the exhaust port 42 is formed at a position where the first housing A and the second housing B are close to each other.
  • the urinalysis apparatus 1 described above is a device that prevents conduction of heat generated by the electric heater 31 of the urine sediment measurement unit 3 to the urine qualitative measurement unit 2, and efficiently discharges the air around the urine qualitative measurement unit 2 to the outside. Since various devices have been made, stable measurement can be performed without causing a heating problem around the urine qualitative measurement unit 2 even when the entire apparatus is made compact.

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Abstract

In a device provided with a urinary sediment analysis unit containing a heater for heating urine samples, and a urine analysis unit, in order to provide a feature for keeping temperature increases within a test range for urinalysis while making the entire device compact, the heater provided to the urinary sediment analysis unit is positioned above the urine analysis unit.

Description

尿検査装置Urinalysis device

　本発明は、尿定性検査及び尿沈渣検査を行うための尿検査装置に関する。 The present invention relates to a urine test apparatus for performing a urine qualitative test and a urine sediment test.

　様々な疾患の可能性を判断するのに、尿検査は非侵襲性、及び得られる情報の多様性から、利用価値が高い。尿検査の方法としては、タンパク質やグルコース、ビリルビン等の成分の濃度を測定する尿定性検査と、赤血球や白血球、上皮細胞等の有形成分を画像方式やフローサイトメーター方式などの光学系を用いて検査する尿沈渣検査が知られている。
　尿沈渣検査は、一般的に、尿定性検査において特定の成分量が異常値を示した場合に、追加の情報を得るために用いられることが多い。従って、従来、尿沈渣検査は、尿定性検査装置を用いて尿定性検査を行った後に、その結果に基づいて尿沈渣検査が必要と判断された被験者の尿を再採取した後に、尿沈渣検査に供することが一般的であった。 The urinalysis is highly useful for judging the possibility of various diseases because it is non-invasive and the variety of information available. As urine testing methods, urine qualitative testing that measures the concentration of components such as protein, glucose, and bilirubin, and optical systems such as red blood cells, white blood cells, and epithelial cells are used for imaging and flow cytometer methods. A urine sediment test is known.
The urine sediment test is generally used to obtain additional information when a specific component amount shows an abnormal value in the urine qualitative test. Therefore, conventionally, urine sediment examination is performed after urine qualitative examination using a urine qualitative examination apparatus, and after re-collecting urine of a subject who is judged to be necessary for urine sediment examination based on the result. It was common to use.

　しかしながら、近年では、データ収集のスピード及び正確さの観点から検査装置の自動化が進んでいる。すなわち、上記のような尿定性検査や尿沈渣検査を、一回に採取した尿検体を用いて単一のシステムで実現し、疾患の診断に必要なデータを包括的に取得する技術が開発されている。例えば、尿定性分析及び尿沈渣分析を自動的に行う尿自動分析装置において、定性項目のうちいずれか１項目で異常値を認めた場合、沈査分析を自動的に行うことを特徴とする尿自動分析装置が知られている（特許文献１）。 However, in recent years, inspection equipment has been automated from the viewpoint of data collection speed and accuracy. In other words, a technology has been developed that enables the urine qualitative test and urine sediment test as described above to be performed in a single system using urine samples collected at a time, and comprehensively acquire data necessary for disease diagnosis. ing. For example, in an automatic urine analyzer that automatically performs urine qualitative analysis and urine sediment analysis, when an abnormal value is recognized in any one of the qualitative items, the urine automatic is characterized by automatically performing a sedimentation analysis. An analyzer is known (Patent Document 1).

特開平６－１０２２７２号公報JP-A-6-102272

　本発明者らは、尿定性検査や尿沈渣検査を一回に採取した尿検体を用いて単一のシステムで実現することを目的とした開発と並行し、尿定性検査に必要な尿定性測定部と尿沈渣検査に必要な尿沈渣測定部とを一体の装置としてコンパクトに設計すべく試行錯誤を重ねている。
　装置をコンパクトにするためには、できるだけ無駄なスペースを生じないように、各部品を配置する必要がある。しかしながら、このような配置を工夫していく過程で、本発明者らは、以下の問題に直面した。
　尿沈渣の分析において、例えば、微小な測定対象物を高精度な光学系で計測するにあたって、温度に因る歪みや特性の変動を最小限にするために、恒温環境で測定する場合がある。このような場合、恒温環境は外気温より高い方が制御が容易なので、30℃より高い温度に設定される。また、測定対象物を高精度に分類するため、変性や染色により特徴を見出すことがある。その場合、反応温度はある温度で一定にする必要があり、例えば、37℃に設定される。この場合、反応部周辺は、常に35℃～40℃に維持しなければならず、特に、37℃前後に維持することが好ましい。
　しかしながら、装置をコンパクトにしようとすると、上記の温度維持のためのヒータが発する熱が尿定性検査の検査領域内に悪影響を与えてしまう。元来、尿定性検査のための装置においては、装置を安定的に稼動させる上で装置内外の空気交換を行うことは必要であったが、検査領域の厳密な温度管理は特段必要なかった。しかしながら、尿定性測定部と尿沈渣測定部とを備えた装置をコンパクトに設計しようとすると、上記尿沈渣測定部のヒータが原因で、尿定性検査を行う検査領域の温度上昇が問題となり、この問題を解消するために当該検査領域の温度管理・調節手段を新たに設けなければならない可能性が浮上した。
　しかしながら、このような温度管理・調節手段を設けることは、そもそも、本発明者らが設定した、装置をコンパクトにするという目的に反するものである。
　そこで、本発明は、尿検体を加温するためのヒータを含む尿沈渣測定部と、尿定性測定部を備える装置において、装置をコンパクトにしながらに、尿定性検査の検査領域内の温度上昇を低減する技術を提供することを課題とする。 In parallel with development aimed at realizing a urine qualitative test and a urine sediment test in a single system using urine samples collected at a time, the present inventors have conducted urine qualitative measurements necessary for urine qualitative tests. And the urine sediment measurement unit necessary for urinary sediment examination are designed as an integrated device in a compact design.
In order to make the apparatus compact, it is necessary to arrange each component so as not to create as much useless space as possible. However, in the process of devising such an arrangement, the present inventors faced the following problems.
In the analysis of urine sediment, for example, when a minute measurement object is measured with a high-precision optical system, the measurement may be performed in a constant temperature environment in order to minimize distortion due to temperature and change in characteristics. In such a case, the constant temperature environment is set to a temperature higher than 30 ° C. because the control is easier when the temperature is higher than the outside air temperature. In addition, in order to classify the measurement object with high accuracy, features may be found by denaturation or staining. In that case, the reaction temperature needs to be constant at a certain temperature, and is set to 37 ° C., for example. In this case, the periphery of the reaction part must always be maintained at 35 ° C. to 40 ° C., particularly preferably around 37 ° C.
However, when trying to make the apparatus compact, the heat generated by the heater for maintaining the temperature adversely affects the examination area of the urine qualitative examination. Originally, in a device for qualitative examination of urine, it was necessary to exchange air inside and outside the device in order to stably operate the device, but strict temperature control in the examination region was not particularly required. However, when trying to compactly design a device equipped with a urine qualitative measurement unit and a urine sediment measurement unit, the temperature rise in the examination region where the urine qualitative test is performed becomes a problem due to the heater of the urine sediment measurement unit. In order to solve the problem, the possibility that a temperature management / adjustment means for the inspection area must be newly provided has emerged.
However, the provision of such temperature management / adjustment means is contrary to the purpose of making the apparatus compact, which was set by the present inventors in the first place.
Accordingly, the present invention provides a device including a urine sediment measurement unit including a heater for heating a urine sample and a urine qualitative measurement unit, and is capable of increasing the temperature in the examination region of the urine qualitative test while making the device compact. It is an object of the present invention to provide a technology for reducing the volume.

　上記課題を解決する本発明は、尿定性検査に必要な測定を行う尿定性測定部と、尿沈渣検査に必要な測定を行う尿沈渣測定部とを備える、尿検査装置であって、前記尿沈渣測定部は、尿検体を加温するヒータを備え、該ヒータは、前記尿定性測定部の上方に配置されていることを特徴とする、尿検査装置（以下、「本発明の尿検査装置」という。）である。
　尿沈渣測定部のヒータを尿定性測定部の上方に配置することで、ヒータからの尿定性測定部への熱伝導を抑えることができる。 The present invention for solving the above problems is a urinalysis apparatus comprising a urine qualitative measurement unit that performs measurements necessary for a urine qualitative test, and a urine sediment measurement unit that performs measurements necessary for a urine sediment test. The sediment measuring unit includes a heater for heating the urine sample, and the heater is disposed above the urine qualitative measuring unit (hereinafter referred to as “the urine testing device of the present invention”). ").
By disposing the heater of the urine sediment measurement unit above the urine qualitative measurement unit, heat conduction from the heater to the urine qualitative measurement unit can be suppressed.

　本発明の尿検査装置の好ましい形態では、前記尿沈渣測定部のヒータは、前記尿定性測定部の斜め上方に配置されている。即ち、前記ヒータと前記尿定性測定部は、鉛直方向、及び水平方向の両方にずれた位置関係にあることが好ましい。
　ヒータを尿定性測定部の斜め上方に配置することで、ヒータからの尿定性測定部への熱伝導を更に抑えることができる。 In a preferred form of the urinalysis apparatus according to the present invention, the heater of the urine sediment measurement unit is disposed obliquely above the urine qualitative measurement unit. That is, it is preferable that the heater and the urine qualitative measurement unit are in a positional relationship shifted in both the vertical direction and the horizontal direction.
By disposing the heater obliquely above the urine qualitative measurement unit, heat conduction from the heater to the urine qualitative measurement unit can be further suppressed.

　本発明の尿検査装置の好ましい形態では、該装置は、前記尿定性測定部の周辺の空気と装置外の空気を交換するための、吸気口及び排気口を備え、該排気口は、前記尿定性測定部の上方に配置され、前記吸気口は、前記排気口の下方に配置されている。
　吸気口及び排気口を上記のように配置することにより、下方から上方へ空気流路を形成することができ、尿定性測定部周辺の熱を効率よく装置外へ排出することが可能となる。特に、尿定性測定部のうち、試験紙に尿検体を点着して反応させている空間（試験紙反応部）の熱を効率よく装置外へ排出するため、当該空間の周辺に空気流路を形成することが好ましい。なお、本発明の尿検査装置において、吸気口及び排気口の数は特に制限されない。 In a preferred form of the urinalysis apparatus according to the present invention, the apparatus includes an intake port and an exhaust port for exchanging air around the urine qualitative measurement unit and air outside the device, and the exhaust port includes the urine It arrange | positions above a qualitative measurement part, and the said inlet port is arrange | positioned under the said exhaust port.
By arranging the intake port and the exhaust port as described above, an air flow path can be formed from the lower side to the upper side, and the heat around the urine qualitative measurement unit can be efficiently discharged out of the apparatus. In particular, in the urine qualitative measurement unit, in order to efficiently exhaust the heat of the space (test paper reaction unit) where the urine sample is spotted on the test paper and reacting, the air flow path around the space Is preferably formed. In the urinalysis apparatus of the present invention, the number of intake ports and exhaust ports is not particularly limited.

　また、本発明の尿検査装置の好ましい形態では、前記尿沈渣測定部のヒータと前記尿定性測定部との間に、前記吸気口から排気口へと連通する空気流路が形成されている。すなわち、尿沈渣測定部のヒータと尿定性測定部との間に空気流路を形成することにより、これらの間に、空気のバリアを形成することができると同時に、ヒータからの熱が尿定性測定部に伝導する前に、当該熱を装置外に排出することができる。 Further, in a preferred embodiment of the urinalysis apparatus of the present invention, an air flow path communicating from the intake port to the exhaust port is formed between the heater of the urine sediment measurement unit and the urine qualitative measurement unit. That is, by forming an air flow path between the heater of the urine sediment measurement unit and the urine qualitative measurement unit, an air barrier can be formed between them, and at the same time, the heat from the heater is qualitatively urine. The heat can be exhausted out of the device before it is conducted to the measuring section.

　本発明の尿検査装置の好ましい形態では、前記尿定性測定部が収容された第１筺体と、前記尿沈渣測定部が収容された第２筺体とを備え、前記吸気口及び排気口は、第１筺体に設けられ、前記排気口は、第１筺体の第２筺体と近接する位置に設けられている。
　吸気口及び排気口を第１筺体に設け、前記排気口を第１筺体の第２筺体と近接する位置に設けることで、尿定性測定部が収容された第１筺体の吸気口から排気口に向かって発生する空気流路の下流側（排気口側）に、尿沈渣測定部が収容された第２筺体が位置することになるので、尿沈渣測定部のヒータが発生する熱を、これが第１筺体内の尿定性測定部に伝導する前に前記空気流路を流れる空気によって装置外に排出することができる。 In a preferred embodiment of the urinalysis apparatus according to the present invention, the urine test apparatus includes a first casing in which the urine qualitative measurement unit is accommodated, and a second casing in which the urine sediment measurement unit is accommodated. Provided in one housing, the exhaust port is provided in a position close to the second housing of the first housing.
An intake port and an exhaust port are provided in the first casing, and the exhaust port is provided at a position close to the second casing of the first casing, so that the intake port of the first casing in which the urine qualitative measurement unit is accommodated is changed to the exhaust port. Since the second housing in which the urine sediment measurement unit is accommodated is located downstream (exhaust port side) of the air flow path generated toward the air flow, the heat generated by the heater of the urine sediment measurement unit is It can be discharged out of the apparatus by the air flowing through the air flow path before being conducted to the urine qualitative measurement unit in the 1-body body.

　また、第１筺体と第２筺体との間には、断熱領域が設けられていることが好ましい。
　これにより、尿沈渣測定部のヒータから尿定性測定部への熱伝導を、より効果的に防ぐことができる。 Moreover, it is preferable that the heat insulation area | region is provided between the 1st housing and the 2nd housing.
Thereby, heat conduction from the heater of the urine sediment measurement unit to the urine qualitative measurement unit can be more effectively prevented.

　本発明の尿検査装置の好ましい形態では、前記第１筺体は、水平方向に突出し上面が露出した突出部を備え、前記尿定性測定部は、前記突出部に設けられ、前記尿沈渣測定部のヒータは、前記第２筺体に設けられている。
　このような構成とすることにより、尿沈渣測定部のヒータから尿定性測定部への熱伝導を極力抑えることができる。これと同時に、尿定性測定部を装置外の外気に比較的近い位置に配置することが可能となり、尿定性測定部の加熱を効率的に防ぐことができる。 In a preferred embodiment of the urinalysis apparatus according to the present invention, the first casing includes a protrusion that protrudes in the horizontal direction and the upper surface is exposed, and the urine qualitative measurement unit is provided in the protrusion, and the urine sediment measurement unit includes: The heater is provided in the second casing.
With this configuration, heat conduction from the heater of the urine sediment measurement unit to the urine qualitative measurement unit can be suppressed as much as possible. At the same time, the urine qualitative measurement unit can be disposed at a position relatively close to the outside air outside the apparatus, and heating of the urine qualitative measurement unit can be efficiently prevented.

　また、本発明の尿検査装置の好ましい形態では、前記尿定性測定部は、尿検体中の特定の成分と反応して呈色する試験紙を投入するための試験紙投入口を備え、該試験紙投入口は、前記突出部の上面に設けられている。
　これにより、装置の上面から、尿定性測定に必要な試験紙を投入することが容易になると同時に、尿定性測定部周辺の温度上昇を抑制することもできる。 Further, in a preferred form of the urinalysis apparatus of the present invention, the urine qualitative measurement unit includes a test paper inlet for introducing a test paper that reacts with a specific component in the urine sample and colors. The paper slot is provided on the upper surface of the protruding portion.
Thereby, it becomes easy to insert test paper necessary for urine qualitative measurement from the upper surface of the apparatus, and at the same time, temperature rise around the urine qualitative measurement unit can be suppressed.

　本発明の尿検査装置は、装置全体をコンパクトにしつつ、尿沈渣測定部のヒータの尿定性測定部への熱伝導を低減することを可能とするものである。 The urinalysis apparatus of the present invention makes it possible to reduce the heat conduction to the urine qualitative measurement part of the heater of the urine sediment measurement part while making the whole apparatus compact.

本発明の尿検査装置の一形態の斜視図である。It is a perspective view of one form of the urinalysis device of the present invention.

　以下、本発明の尿検査装置の一形態を図面を参照しながら説明する。 Hereinafter, an embodiment of the urine test apparatus of the present invention will be described with reference to the drawings.

　図１に示す尿検査装置１は、尿定性測定部２が収容された第１筺体Ａ、尿沈渣測定部３が収容された第２筺体Ｂ、尿検体を収容する採尿管をノズル５１、及び５２による採取位置に供給する検体供給部Ｃを備える。
　第１筐体Ａは、正面から見て凸形状、第２筐体Ｂは、正面から見て逆Ｌ字形状である。第２筐体Ｂは、第１筐体Ａの左側の上方空間を埋めるように、第１筐体Ａと連結されている。このように筐体を配置することにより、装置全体の省スペースを実現している。第１筐体Ａは、水平方向に突出し上面が露出した突出部Ａ１を有する。
　第１筐体Ａと第２筐体Ｂとの間には、断熱領域であるギャップｇが設けられている。これにより、後述するヒータ３１からの尿定性測定部２への熱伝導を効率よく防ぐことができる。なお、上記ギャップの代わりに、両筐体の間に断熱材を設けることも可能である。 A urinalysis apparatus 1 shown in FIG. 1 includes a first casing A in which a urine qualitative measurement unit 2 is stored, a second casing B in which a urine sediment measurement unit 3 is stored, a urine collection tube that stores a urine sample, a nozzle 51, and A sample supply unit C that supplies the sample to the collection position 52 is provided.
The first housing A has a convex shape when viewed from the front, and the second housing B has an inverted L shape when viewed from the front. The second housing B is connected to the first housing A so as to fill the upper space on the left side of the first housing A. By arranging the housing in this way, space saving of the entire apparatus is realized. The 1st housing | casing A has protrusion part A1 which protruded in the horizontal direction and the upper surface was exposed.
A gap g, which is a heat insulating region, is provided between the first housing A and the second housing B. Thereby, heat conduction from the heater 31 to be described later to the urine qualitative measurement unit 2 can be efficiently prevented. In addition, it is also possible to provide a heat insulating material between both housings instead of the gap.

　上記筐体の形状は、特に制限されるものではなく、省スペースの観点から適宜変更することが可能である。また、本発明の尿検査装置は、必ずしも２つの筐体で区画する必要はなく、更に複数の筐体で区画してもよいし、１つの筐体を用い、該筺体内を必要に応じて断熱材を用いて区画してもよい。 The shape of the casing is not particularly limited, and can be changed as appropriate from the viewpoint of space saving. Further, the urinalysis apparatus of the present invention does not necessarily need to be partitioned by two housings, and may be partitioned by a plurality of housings. You may partition using a heat insulating material.

　第１筐体Ａは、尿定性測定部２、吸気口４１、排気口４２、及びノズル５１を備える。ノズル５１は、検体供給部Ｃ上の採尿管から尿検体を採取し、必要な測定を行うために、尿検体を尿定性測定部２の試験紙反応部（図示しない）へ搬送された試験紙へ点着する。
　尿定性測定部２は、尿検体中の特定の成分と反応して呈色する試験紙を用いて、該呈色を光学的に検出し、尿検体中の成分についてのデータを取得する部分であり、第１筐体Ａの突出部Ａ１に設けられている。尿定性測定部２を突出部Ａ１に設けることにより、尿定性測定部２が装置外に近い位置に配置されることとなるので、尿定性測定部２の加熱を効率的に防ぐことができる。
　尿定性測定部２は、試験紙を収納するための試験紙収納槽２１、ノズルで吸引した検体を点着させて反応させる試験紙反応部（図示しない）、試験紙の呈色を検出する反射光学系（図示しない）、検出結果を処理、分析し、出力データを生成したり、装置の駆動系を制御したりする制御部（図示しない）などを備える。なお、これらの構成は、何れも尿定性検査のための分析を行う従来の装置が通常備えているものであり、ここで具体的に説明するまでもなく、その構成を当業者が理解できるものである。
　前記試験紙収納槽２１は、試験紙を投入するための試験紙投入口２２を備え、該試験紙投入口２２は、突出部Ａ１の上面に設けられている。これより、試験紙を装置外から容易に投入することができる。また、尿定性測定部２が装置外の外気に更に近い位置に配置されることとなるので、尿定性測定部２の加熱を効率的に防ぐことができる。 The first housing A includes the urine qualitative measurement unit 2, an intake port 41, an exhaust port 42, and a nozzle 51. The nozzle 51 collects a urine sample from a urine collection tube on the sample supply unit C and transports the urine sample to a test paper reaction unit (not shown) of the urine qualitative measurement unit 2 in order to perform necessary measurements. To spot.
The urine qualitative measurement unit 2 is a part that optically detects the coloration using a test paper that reacts with a specific component in the urine sample and develops color, and acquires data on the component in the urine sample. Yes, provided in the protrusion A1 of the first housing A. By providing the urine qualitative measurement unit 2 in the protruding portion A1, the urine qualitative measurement unit 2 is disposed at a position close to the outside of the apparatus, so that the urine qualitative measurement unit 2 can be efficiently prevented from being heated.
The urine qualitative measurement unit 2 is a test paper storage tank 21 for storing test paper, a test paper reaction unit (not shown) for spotting and reacting a sample sucked by a nozzle, and a reflection for detecting the color of the test paper An optical system (not shown), a control unit (not shown) that processes and analyzes the detection result, generates output data, and controls the drive system of the apparatus are included. These configurations are usually provided by a conventional apparatus that performs analysis for urine qualitative testing, and those configurations can be understood by those skilled in the art without needing to be specifically described here. It is.
The test paper storage tank 21 is provided with a test paper input port 22 for inputting test paper, and the test paper input port 22 is provided on the upper surface of the protruding portion A1. Thus, the test paper can be easily loaded from outside the apparatus. Moreover, since the urine qualitative measurement part 2 will be arrange | positioned in the position still closer to the external air outside an apparatus, the heating of the urine qualitative measurement part 2 can be prevented efficiently.

　吸気口４１は、第１筐体Ａの突出部Ａ１の右側面に設けられ、排気口４２は、第１筐体Ａの凸形状の上部背面に設けられている。また、排気口４２は、空気を装置外に排出するためのファン４３を備えている。なお、当業者に明らかな通り、吸気口から吸入した空気を排気口に送るためには、ファン以外の機構を用いることもできる。また、ファンを使用する場合のファンの位置は、排気口からの空気の排出を可能にする限り特に制限されない。本形態において、吸気口４１と排気口４２により形成される空気流路ｐは、尿定性測定部２の周辺に位置しているので、尿定性測定部周辺の空気を装置外の空気と効率よく交換することができる。また、排気口４２が吸気口４１の上方に位置しているので、加温された空気を効率よく排出することができる。
　なお、本形態においては、吸気口と排気口の数は各々１つであるが、これを複数設けても構わない。また、吸気口と排気口の位置も、尿定性測定部の周辺の空気を排出することが可能である限り、特に制限されない。 The intake port 41 is provided on the right side surface of the protruding portion A1 of the first housing A, and the exhaust port 42 is provided on the convex upper back surface of the first housing A. Further, the exhaust port 42 includes a fan 43 for exhausting air out of the apparatus. As will be apparent to those skilled in the art, a mechanism other than a fan can be used to send the air sucked from the intake port to the exhaust port. Further, the position of the fan when using the fan is not particularly limited as long as the air can be discharged from the exhaust port. In this embodiment, since the air flow path p formed by the intake port 41 and the exhaust port 42 is located around the urine qualitative measurement unit 2, the air around the urine qualitative measurement unit is efficiently exchanged with the air outside the device. Can be exchanged. Moreover, since the exhaust port 42 is located above the intake port 41, the heated air can be discharged efficiently.
In this embodiment, the number of intake ports and exhaust ports is one, but a plurality of them may be provided. Further, the positions of the intake port and the exhaust port are not particularly limited as long as the air around the urine qualitative measurement unit can be discharged.

　第２筐体Ｂは、尿沈渣測定部３、及びノズル５２を備える。ノズル５２は、検体供給部Ｃ上の採尿管から尿検体を採取し、必要な測定を行うために、尿沈渣測定部３の検体槽（図示しない）へ供給する。なお、上述した第１筺体Ａに備えられたノズル５１に連結する供給管の構成を適宜変更することにより、上述したノズル５１を尿沈渣測定部３への尿検体の供給機構として使用することも可能である。
　尿沈渣測定部３は、尿検体中の固形成分の画像ないし光学的特徴量を取得し、個々のデータから固形成分を分析する。
　尿沈渣測定部３は、尿検体を収容する検体槽、検体槽内の尿検体および尿検体を染色或いは変性させる反応部や光学系（フローサイトメーターなど）を３７℃前後の温度に維持するための温度センサ及び温度制御部（何れも図示しない）、尿検体を加温するための電熱ヒータ３１、尿検体の固形成分を撮影するための光学系（フローサイトメーターなど）（図示しない）、画像や光学的特徴量を処理、分析し、出力データを生成したり、装置の駆動系を制御したりする制御部（図示しない）等を備える。なお、これらの構成は、何れも尿沈渣検査のための分析を行う従来の装置が通常備えるものであり、具体的に記載するまでもなく、その構成を当業者が理解できるものである。 The second housing B includes the urine sediment measurement unit 3 and the nozzle 52. The nozzle 52 collects a urine sample from a urine collection tube on the sample supply unit C, and supplies the sample to a sample tank (not shown) of the urine sediment measurement unit 3 in order to perform necessary measurements. In addition, the nozzle 51 described above may be used as a mechanism for supplying the urine sample to the urine sediment measuring unit 3 by appropriately changing the configuration of the supply pipe connected to the nozzle 51 provided in the first casing A described above. Is possible.
The urine sediment measurement unit 3 acquires an image or optical feature amount of a solid component in the urine sample, and analyzes the solid component from individual data.
The urine sediment measurement unit 3 maintains a sample tank for storing a urine sample, a urine sample in the sample tank, a reaction unit for staining or denaturing the urine sample, and an optical system (such as a flow cytometer) at a temperature of about 37 ° C. Temperature sensor and temperature control unit (both not shown), an electric heater 31 for heating the urine sample, an optical system (such as a flow cytometer) for imaging the solid component of the urine sample (not shown), an image And a control unit (not shown) that processes and analyzes the optical feature quantity, generates output data, and controls the drive system of the apparatus. These configurations are usually provided in a conventional apparatus for performing analysis for urinary sediment examination, and those configurations can be understood by those skilled in the art without specific description.

　尿検査装置１では、第１筐体Ａと第２筐体Ｂとが近接する位置に、上述した吸気口４１から排気口４２へと連通する空気流路ｐが、形成されている。これにより、第２筐体Ｂに備えられた尿沈渣測定部３の電熱ヒータ３１の熱が、第１筐体Ａの尿定性測定部２の周辺に伝わる前に、当該熱を効率よく装置外に排出することが可能となっている。特に、空気流路ｐの下流側が電熱ヒータ３１に比較的近い位置となっているため、これにより発せられる熱を効率よく装置外に排出することができる。 In the urinalysis apparatus 1, the air flow path p communicating from the intake port 41 to the exhaust port 42 is formed at a position where the first housing A and the second housing B are close to each other. Thereby, before the heat of the electric heater 31 of the urine sediment measurement unit 3 provided in the second casing B is transmitted to the periphery of the urine qualitative measurement unit 2 of the first casing A, the heat is efficiently transferred to the outside of the apparatus. Can be discharged. In particular, since the downstream side of the air flow path p is relatively close to the electric heater 31, the heat generated thereby can be efficiently discharged out of the apparatus.

　以上説明した尿検査装置１は、尿沈渣測定部３の電熱ヒータ３１が発する熱の尿定性測定部２への伝導を防ぐ工夫、尿定性測定部２の周辺の空気を効率よく装置外に排出する工夫が種々なされているので、装置全体をコンパクトにした場合でも、尿定性測定部２の周辺の加熱の問題を生ずることなく、安定した測定が可能となる。 The urinalysis apparatus 1 described above is a device that prevents conduction of heat generated by the electric heater 31 of the urine sediment measurement unit 3 to the urine qualitative measurement unit 2, and efficiently discharges the air around the urine qualitative measurement unit 2 to the outside. Since various devices have been made, stable measurement can be performed without causing a heating problem around the urine qualitative measurement unit 2 even when the entire apparatus is made compact.

　１・・・尿検査装置
　Ａ・・・第１筺体
　Ａ１・・・突出部
　Ｃ・・・検体供給部
　Ｂ・・・第２筺体
　２・・・尿定性測定部
　２１・・・試験紙収納槽
　２２・・・試験紙投入口
　３・・・尿沈渣測定部
　３１・・・ヒータ
　４１・・・吸気口
　４２・・・排気口
　４３・・・ファン
　５１・・・ノズル
　５２・・・ノズル DESCRIPTION OF SYMBOLS 1 ... Urine test apparatus A ... 1st housing A1 ... Projection part C ... Specimen supply part B ... 2nd housing 2 ... Urine qualitative measurement part 21 ... Test paper storage tank 22 ... Test paper inlet 3 ... Urine sediment measurement part 31 ... Heater 41 ... Intake port 42 ... Exhaust port 43 ... Fan 51 ... Nozzle 52 ... Nozzle

Claims (8)

　尿定性検査に必要な測定を行う尿定性測定部と、尿沈渣検査に必要な測定を行う尿沈渣測定部とを備える、尿検査装置であって、
　前記尿沈渣測定部は、尿検体を加温するヒータを備え、
　該ヒータは、前記尿定性測定部の上方に配置されていることを特徴とする、尿検査装置。 A urinalysis apparatus comprising a urine qualitative measurement unit that performs measurements necessary for a urine qualitative test and a urine sediment measurement unit that performs measurements necessary for a urine sediment test,
The urine sediment measurement unit includes a heater for heating the urine sample,
The urinalysis apparatus is characterized in that the heater is disposed above the urine qualitative measurement unit. 　前記尿沈渣測定部のヒータは、前記尿定性測定部の斜め上方に配置されていることを特徴とする、請求項１に記載の尿検査装置。 2. The urine test apparatus according to claim 1, wherein the heater of the urine sediment measurement unit is disposed obliquely above the urine qualitative measurement unit. 　前記尿検査装置は、前記尿定性測定部の周辺の空気と装置外の空気とを交換するための、吸気口及び排気口を備え、
　該排気口は、前記尿定性測定部の上方に配置され、前記吸気口は、前記排気口の下方に配置されていることを特徴とする、請求項１又は２に記載の尿検査装置。 The urinalysis apparatus includes an intake port and an exhaust port for exchanging air around the urine qualitative measurement unit and air outside the device,
The urinalysis apparatus according to claim 1, wherein the exhaust port is disposed above the urine qualitative measurement unit, and the intake port is disposed below the exhaust port. 　前記尿沈渣測定部のヒータと前記尿定性測定部との間に、前記吸気口から排気口へと連通する空気流路が形成されていることを特徴とする、請求項３に記載の尿検査装置。 The urine test according to claim 3, wherein an air flow path communicating from the intake port to the exhaust port is formed between the heater of the urine sediment measurement unit and the urine qualitative measurement unit. apparatus. 　前記尿定性測定部が収容された第１筺体と、前記尿沈渣測定部が収容された第２筺体とを備え、
　前記吸気口及び排気口は、第１筺体に設けられ、
　前記排気口は、第１筺体の第２筺体と近接する位置に設けられていることを特徴とする、請求項３又は４に記載の尿検査装置。 A first housing containing the urine qualitative measurement unit; and a second housing containing the urine sediment measurement unit;
The intake port and the exhaust port are provided in the first housing,
The urinalysis apparatus according to claim 3 or 4, wherein the exhaust port is provided at a position close to the second casing of the first casing. 　第１筺体と第２筺体との間に断熱領域が設けられていることを特徴とする、請求項５に記載の尿検査装置。 6. The urinalysis apparatus according to claim 5, wherein a heat insulating region is provided between the first housing and the second housing. 　前記第１筺体は、水平方向に突出し上面が露出した突出部を備え、
　前記尿定性測定部は、前記突出部に設けられ、
　前記尿沈渣測定部のヒータは、前記第２筺体に設けられていることを特徴とする、請求項５又は６に記載の尿検査装置。 The first housing includes a protruding portion protruding in a horizontal direction and having an upper surface exposed,
The urine qualitative measurement unit is provided in the protrusion,
The urinalysis apparatus according to claim 5 or 6, wherein the heater of the urine sediment measurement unit is provided in the second casing. 　前記尿定性測定部は、尿検体中の特定の成分と反応して呈色する試験紙を投入するための試験紙投入口を備え、
　該試験紙投入口は、前記突出部の上面に設けられていることを特徴とする、請求項７に記載の尿検査装置。 The urine qualitative measurement unit includes a test paper inlet for introducing a test paper that reacts with a specific component in a urine sample and gives a color.
The urinalysis apparatus according to claim 7, wherein the test paper inlet is provided on an upper surface of the protrusion.
PCT/JP2011/061187 2010-05-31 2011-05-16 Urine analyzer Ceased WO2011152193A1 (en)

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