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WO2011014855A3 - Désoxygénation de fluides biologiques - Google Patents

Désoxygénation de fluides biologiques Download PDF

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Publication number
WO2011014855A3
WO2011014855A3 PCT/US2010/044045 US2010044045W WO2011014855A3 WO 2011014855 A3 WO2011014855 A3 WO 2011014855A3 US 2010044045 W US2010044045 W US 2010044045W WO 2011014855 A3 WO2011014855 A3 WO 2011014855A3
Authority
WO
WIPO (PCT)
Prior art keywords
oxygen
tubes
removal
biological fluids
concentration
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/US2010/044045
Other languages
English (en)
Other versions
WO2011014855A2 (fr
Inventor
William J. Federspiel
Tatsuro Yoshida
Paul J. Vernucci
Brian Joseph Frankowski
Laura Wheeler Lund
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of Pittsburgh
Hemanext Inc
Original Assignee
University of Pittsburgh
New Health Sciences Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University of Pittsburgh, New Health Sciences Inc filed Critical University of Pittsburgh
Priority to AU2010278768A priority Critical patent/AU2010278768A1/en
Priority to US13/387,528 priority patent/US20120129149A1/en
Priority to JP2012523121A priority patent/JP5770183B2/ja
Priority to EP10805155.8A priority patent/EP2459247A4/fr
Priority to CA2772320A priority patent/CA2772320A1/fr
Priority to NZ598410A priority patent/NZ598410A/en
Publication of WO2011014855A2 publication Critical patent/WO2011014855A2/fr
Publication of WO2011014855A3 publication Critical patent/WO2011014855A3/fr
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D63/00—Apparatus in general for separation processes using semi-permeable membranes
    • B01D63/02—Hollow fibre modules
    • B01D63/021—Manufacturing thereof
    • B01D63/022—Encapsulating hollow fibres
    • B01D63/0221—Encapsulating hollow fibres using a mould
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/02—Blood transfusion apparatus
    • A61M1/0209—Multiple bag systems for separating or storing blood components
    • A61M1/0218—Multiple bag systems for separating or storing blood components with filters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/34—Filtering material out of the blood by passing it through a membrane, i.e. hemofiltration or diafiltration
    • A61M1/3472—Filtering material out of the blood by passing it through a membrane, i.e. hemofiltration or diafiltration with treatment of the filtrate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/34—Filtering material out of the blood by passing it through a membrane, i.e. hemofiltration or diafiltration
    • A61M1/3472—Filtering material out of the blood by passing it through a membrane, i.e. hemofiltration or diafiltration with treatment of the filtrate
    • A61M1/3475—Filtering material out of the blood by passing it through a membrane, i.e. hemofiltration or diafiltration with treatment of the filtrate with filtrate treatment agent in the same enclosure as the membrane
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/34—Filtering material out of the blood by passing it through a membrane, i.e. hemofiltration or diafiltration
    • A61M1/3472—Filtering material out of the blood by passing it through a membrane, i.e. hemofiltration or diafiltration with treatment of the filtrate
    • A61M1/3486—Biological, chemical treatment, e.g. chemical precipitation; treatment by absorbents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/3679—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits by absorption
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D63/00—Apparatus in general for separation processes using semi-permeable membranes
    • B01D63/02—Hollow fibre modules
    • B01D63/04—Hollow fibre modules comprising multiple hollow fibre assemblies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/02—Blood transfusion apparatus
    • A61M1/0209—Multiple bag systems for separating or storing blood components
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/02—Blood transfusion apparatus
    • A61M1/0272—Apparatus for treatment of blood or blood constituents prior to or for conservation, e.g. freezing, drying or centrifuging
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/02—Blood transfusion apparatus
    • A61M1/0281—Apparatus for treatment of blood or blood constituents prior to transfusion, e.g. washing, filtering or thawing
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/14—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
    • A61M1/16—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with membranes
    • A61M1/1621—Constructional aspects thereof
    • A61M1/1623—Disposition or location of membranes relative to fluids
    • A61M1/1625—Dialyser of the outside perfusion type, i.e. blood flow outside hollow membrane fibres or tubes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/14—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
    • A61M1/16—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with membranes
    • A61M1/1621—Constructional aspects thereof
    • A61M1/1623—Disposition or location of membranes relative to fluids
    • A61M1/1627—Dialyser of the inside perfusion type, i.e. blood flow inside hollow membrane fibres or tubes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2202/00—Special media to be introduced, removed or treated
    • A61M2202/02—Gases
    • A61M2202/0208—Oxygen
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D2311/00—Details relating to membrane separation process operations and control
    • B01D2311/13—Use of sweep gas
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D2311/00—Details relating to membrane separation process operations and control
    • B01D2311/26—Further operations combined with membrane separation processes
    • B01D2311/2626—Absorption or adsorption
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D2313/00—Details relating to membrane modules or apparatus
    • B01D2313/40—Adsorbents within the flow path

Landscapes

  • Health & Medical Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Vascular Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Hematology (AREA)
  • Veterinary Medicine (AREA)
  • Anesthesiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biodiversity & Conservation Biology (AREA)
  • Cell Biology (AREA)
  • Molecular Biology (AREA)
  • Manufacturing & Machinery (AREA)
  • Cardiology (AREA)
  • External Artificial Organs (AREA)
  • Separation Using Semi-Permeable Membranes (AREA)

Abstract

L'invention concerne un système de réduction de la concentration d'oxygène dans un fluide comportant des globules rouges comprenant un boîtier, une pluralité de tubes creux s'étendant à l'intérieur du boîtier et conçus pour que le fluide les traverse en s'écoulant, chaque tube comportant une entrée et une sortie, et un système vecteur réduisant la concentration d'oxygène sur une surface extérieure des tubes pour faciliter le transport d'oxygène du fluide s'écoulant à travers les tubes vers l'extérieur des tubes.
PCT/US2010/044045 2009-07-31 2010-07-31 Désoxygénation de fluides biologiques Ceased WO2011014855A2 (fr)

Priority Applications (6)

Application Number Priority Date Filing Date Title
AU2010278768A AU2010278768A1 (en) 2009-07-31 2010-07-31 Removal of oxygen from biological fluids
US13/387,528 US20120129149A1 (en) 2009-07-31 2010-07-31 Removal of oxygen from biological fluids
JP2012523121A JP5770183B2 (ja) 2009-07-31 2010-07-31 生体液からの酸素除去
EP10805155.8A EP2459247A4 (fr) 2009-07-31 2010-07-31 Désoxygénation de fluides biologiques
CA2772320A CA2772320A1 (fr) 2009-07-31 2010-07-31 Desoxygenation de fluides biologiques
NZ598410A NZ598410A (en) 2009-07-31 2010-07-31 Removal of oxygen from biological fluids

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US23057509P 2009-07-31 2009-07-31
US61/230,575 2009-07-31

Publications (2)

Publication Number Publication Date
WO2011014855A2 WO2011014855A2 (fr) 2011-02-03
WO2011014855A3 true WO2011014855A3 (fr) 2011-06-16

Family

ID=43529974

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2010/044045 Ceased WO2011014855A2 (fr) 2009-07-31 2010-07-31 Désoxygénation de fluides biologiques

Country Status (7)

Country Link
US (1) US20120129149A1 (fr)
EP (1) EP2459247A4 (fr)
JP (1) JP5770183B2 (fr)
AU (1) AU2010278768A1 (fr)
CA (1) CA2772320A1 (fr)
NZ (1) NZ598410A (fr)
WO (1) WO2011014855A2 (fr)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8828226B2 (en) 2003-03-01 2014-09-09 The Trustees Of Boston University System for assessing the efficacy of stored red blood cells using microvascular networks
US11284616B2 (en) 2010-05-05 2022-03-29 Hemanext Inc. Irradiation of red blood cells and anaerobic storage
US9199016B2 (en) 2009-10-12 2015-12-01 New Health Sciences, Inc. System for extended storage of red blood cells and methods of use
WO2011046841A1 (fr) 2009-10-12 2011-04-21 New Health Sciences, Inc. Système de sac de stockage de sang et dispositifs d'épuisement avec capacités d'épuisement en dioxyde de carbone et en oxygène
US10136635B2 (en) 2010-05-05 2018-11-27 New Health Sciences, Inc. Irradiation of red blood cells and anaerobic storage
JP2013507447A (ja) * 2009-10-12 2013-03-04 ニュー ヘルス サイエンシーズ、インク． 酸素減損装置及び赤血球から酸素を除去する方法
US12089589B2 (en) 2009-10-12 2024-09-17 Hemanext Inc. Irradiation of red blood cells and anaerobic storage
EP2608816B1 (fr) 2010-08-25 2023-07-05 Hemanext Inc. Procédé pour augmenter la qualité et la survie pendant la conservation d'érythrocytes
CA2830420A1 (fr) 2011-03-16 2012-09-20 Mayo Foundation For Medical Education And Research Procedes et materiaux pour prolonger le stockage utile des preparations d'hematies et des preparations de plaquettes
CA2831465C (fr) * 2011-03-28 2018-02-27 New Health Sciences, Inc. Procede et systeme pour eliminer l'oxygene et le dioxyde de carbone pendant le traitement d'erythrocytes en utilisant un gaz vecteur inerte et ensemble de collecteur
US9067004B2 (en) 2011-03-28 2015-06-30 New Health Sciences, Inc. Method and system for removing oxygen and carbon dioxide during red cell blood processing using an inert carrier gas and manifold assembly
DE102011052187A1 (de) * 2011-07-27 2013-01-31 Maquet Vertrieb Und Service Deutschland Gmbh Anordnung zum Entfernen von Kohlenstoffdioxid aus einem exkorporalen Blutstrom mittels Inertgasen
AU2012294269B2 (en) 2011-08-10 2016-11-24 Hemanext Inc. Integrated leukocyte, oxygen and/or CO2 depletion, and plasma separation filter device
GB201207543D0 (en) * 2012-05-01 2012-06-13 Haemair Ltd Treatment of transfusion blood
EP2961269B1 (fr) * 2013-02-28 2021-09-15 Hemanext Inc. Dispositif d'appauvrissement de gaz dans les produits sanguins
AU2016228993B2 (en) 2015-03-10 2022-02-10 Hemanext Inc. Oxygen reduction disposable kits, devices and methods of use thereof
KR102661405B1 (ko) 2015-04-23 2024-04-25 헤마넥스트 인코포레이티드 혐기성 혈액 저장 용기
CA2985799A1 (fr) 2015-05-18 2016-11-24 New Health Sciences, Inc. Procedes pour le stockage de sang total et compositions correspondantes
US11147876B2 (en) 2016-05-27 2021-10-19 Hemanext Inc. Anaerobic blood storage and pathogen inactivation method
CN113365642A (zh) * 2018-11-16 2021-09-07 希玛奈克斯特股份有限公司 用于控制炎症患者中不良事件的方法
CN115154714B (zh) * 2022-06-06 2024-12-20 大连理工大学 一种高性能膜-吸附耦合式氧合器

Citations (4)

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US4749551A (en) * 1985-09-24 1988-06-07 Sorin Biomedica S.P.A. Hollow-fiber oxygenators for blood
US5192320A (en) * 1987-07-11 1993-03-09 Dainippon Ink And Chemicals Inc. Artificial lung and method of using it
US6162396A (en) * 1997-04-26 2000-12-19 The Regents Of The University Of California Blood storage device and method for oxygen removal
WO2006057473A1 (fr) * 2004-11-23 2006-06-01 Newheart Bio Co., Ltd. Module de filtre muni de parties multifonctionnelles correspondantes avec purification et/ou oxygenation de sang et procede de purification de sang ainsi que dispositif de purification et d'oxygenation de sang comprenant ce module

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Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4749551A (en) * 1985-09-24 1988-06-07 Sorin Biomedica S.P.A. Hollow-fiber oxygenators for blood
US5192320A (en) * 1987-07-11 1993-03-09 Dainippon Ink And Chemicals Inc. Artificial lung and method of using it
US6162396A (en) * 1997-04-26 2000-12-19 The Regents Of The University Of California Blood storage device and method for oxygen removal
WO2006057473A1 (fr) * 2004-11-23 2006-06-01 Newheart Bio Co., Ltd. Module de filtre muni de parties multifonctionnelles correspondantes avec purification et/ou oxygenation de sang et procede de purification de sang ainsi que dispositif de purification et d'oxygenation de sang comprenant ce module

Also Published As

Publication number Publication date
AU2010278768A1 (en) 2012-03-15
NZ598410A (en) 2014-04-30
EP2459247A2 (fr) 2012-06-06
JP5770183B2 (ja) 2015-08-26
JP2013500794A (ja) 2013-01-10
CA2772320A1 (fr) 2011-02-03
EP2459247A4 (fr) 2013-08-28
WO2011014855A2 (fr) 2011-02-03
US20120129149A1 (en) 2012-05-24

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