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WO2011014025A3 - Derivative of hydroxy-cinnamic acid in which a peptide has been bonded, production method for same, and cosmetic composition comprising same - Google Patents

Derivative of hydroxy-cinnamic acid in which a peptide has been bonded, production method for same, and cosmetic composition comprising same Download PDF

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Publication number
WO2011014025A3
WO2011014025A3 PCT/KR2010/004999 KR2010004999W WO2011014025A3 WO 2011014025 A3 WO2011014025 A3 WO 2011014025A3 KR 2010004999 W KR2010004999 W KR 2010004999W WO 2011014025 A3 WO2011014025 A3 WO 2011014025A3
Authority
WO
WIPO (PCT)
Prior art keywords
same
peptide
hydroxy
derivative
bonded
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/KR2010/004999
Other languages
French (fr)
Korean (ko)
Other versions
WO2011014025A2 (en
Inventor
이윤식
곽선영
서효석
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
SNU R&DB Foundation
Original Assignee
SNU R&DB Foundation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by SNU R&DB Foundation filed Critical SNU R&DB Foundation
Publication of WO2011014025A2 publication Critical patent/WO2011014025A2/en
Publication of WO2011014025A3 publication Critical patent/WO2011014025A3/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C225/00—Compounds containing amino groups and doubly—bound oxygen atoms bound to the same carbon skeleton, at least one of the doubly—bound oxygen atoms not being part of a —CHO group, e.g. amino ketones
    • C07C225/02—Compounds containing amino groups and doubly—bound oxygen atoms bound to the same carbon skeleton, at least one of the doubly—bound oxygen atoms not being part of a —CHO group, e.g. amino ketones having amino groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C225/14—Compounds containing amino groups and doubly—bound oxygen atoms bound to the same carbon skeleton, at least one of the doubly—bound oxygen atoms not being part of a —CHO group, e.g. amino ketones having amino groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being unsaturated
    • C07C225/16—Compounds containing amino groups and doubly—bound oxygen atoms bound to the same carbon skeleton, at least one of the doubly—bound oxygen atoms not being part of a —CHO group, e.g. amino ketones having amino groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being unsaturated and containing six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A61Q19/02—Preparations for care of the skin for chemically bleaching or whitening the skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A61Q19/08—Anti-ageing preparations
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06104—Dipeptides with the first amino acid being acidic
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06139—Dipeptides with the first amino acid being heterocyclic
    • C07K5/06165—Dipeptides with the first amino acid being heterocyclic and Pro-amino acid; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08—Tripeptides
    • C07K5/0802—Tripeptides with the first amino acid being neutral
    • C07K5/0804—Tripeptides with the first amino acid being neutral and aliphatic
    • C07K5/0806—Tripeptides with the first amino acid being neutral and aliphatic the side chain containing 0 or 1 carbon atoms, i.e. Gly, Ala
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08—Tripeptides
    • C07K5/0802—Tripeptides with the first amino acid being neutral
    • C07K5/0804—Tripeptides with the first amino acid being neutral and aliphatic
    • C07K5/0808—Tripeptides with the first amino acid being neutral and aliphatic the side chain containing 2 to 4 carbon atoms, e.g. Val, Ile, Leu
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08—Tripeptides
    • C07K5/0802—Tripeptides with the first amino acid being neutral
    • C07K5/0812—Tripeptides with the first amino acid being neutral and aromatic or cycloaliphatic
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/10—Tetrapeptides
    • C07K5/1002—Tetrapeptides with the first amino acid being neutral
    • C07K5/1005—Tetrapeptides with the first amino acid being neutral and aliphatic
    • C07K5/101—Tetrapeptides with the first amino acid being neutral and aliphatic the side chain containing 2 to 4 carbon atoms, e.g. Val, Ile, Leu
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/10—Tetrapeptides
    • C07K5/1024—Tetrapeptides with the first amino acid being heterocyclic
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/52—Stabilizers
    • A61K2800/522—Antioxidants; Radical scavengers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Dermatology (AREA)
  • Epidemiology (AREA)
  • Birds (AREA)
  • Gerontology & Geriatric Medicine (AREA)
  • Cosmetics (AREA)
  • Peptides Or Proteins (AREA)

Abstract

The present invention relates to a derivative of hydroxy-cinnamic acid in which a peptide has been bonded, a production method for the same, and a cosmetic composition comprising the same. More specifically, the present invention concerns a derivative of hydroxy-cinnamic acid in which a peptide having an antioxidant effect has been bonded, a production method for the same, and a cosmetic composition for skin whitening and aging prevention which comprises the same and thereby has an enhanced anti-oxidant effect and no cell toxicity.
PCT/KR2010/004999 2009-07-30 2010-07-29 Derivative of hydroxy-cinnamic acid in which a peptide has been bonded, production method for same, and cosmetic composition comprising same Ceased WO2011014025A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR1020090069734A KR20110012148A (en) 2009-07-30 2009-07-30 Hydroxy cinnamic acid derivatives to which the peptide is bound, a preparation method thereof, and a cosmetic composition comprising the same
KR10-2009-0069734 2009-07-30

Publications (2)

Publication Number Publication Date
WO2011014025A2 WO2011014025A2 (en) 2011-02-03
WO2011014025A3 true WO2011014025A3 (en) 2011-06-30

Family

ID=43529886

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/KR2010/004999 Ceased WO2011014025A2 (en) 2009-07-30 2010-07-29 Derivative of hydroxy-cinnamic acid in which a peptide has been bonded, production method for same, and cosmetic composition comprising same

Country Status (2)

Country Link
KR (1) KR20110012148A (en)
WO (1) WO2011014025A2 (en)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2013166438A1 (en) * 2012-05-04 2013-11-07 The Board Of Regents Of The University Of Oklahoma Substrates and inhibitors of prolyl oligopeptidase and fibroblast activation protein and methods of use
KR101710486B1 (en) * 2015-01-05 2017-02-28 주식회사 앤코스메슈 Oligopeptide derivatives and skin wrinkle composition comprising it
KR101705338B1 (en) * 2015-10-26 2017-02-09 주식회사 인코스팜 A composition having anti-oxidant, anti-aging and autophagy activity and use thereof
KR102101339B1 (en) * 2017-03-29 2020-04-16 주식회사 비드테크 Composition for preventing or treating skin disease Inflammatory and method for preparing thereof
BR112017018828B1 (en) 2017-04-27 2022-10-11 Caregen Co., Ltd. PEPTIDE HAVING SKIN WHITENING ACTIVITY, ITS USES AND SKIN WHITENING COMPOSITION
KR101970465B1 (en) * 2017-06-09 2019-04-22 주식회사 바이오에프디엔씨 Use of novel peptide derivatives derived from silkworm that coupled with caffeic acid
KR102124912B1 (en) * 2018-05-24 2020-06-19 원광대학교 산학협력단 Novel Oligopeptide Derivatives and Use therof
KR101958207B1 (en) * 2018-09-13 2019-03-14 (주)케어젠 Peptide for Skin Whitening and Use Thereof
KR102394875B1 (en) * 2021-05-11 2022-05-06 주식회사 비드테크 Compound combined pyrrolidine linker and pharmaceutical composition comprising the same
KR102404228B1 (en) * 2022-02-18 2022-05-31 주식회사 차메디텍 Composition including reduced lipoic acid-peptide derivative that increases the antioxidant effect and method of preparing the same
CN115581633B (en) * 2022-10-14 2023-09-12 深圳市维琪科技股份有限公司 New use of peptide compounds in preparation of composition for skin aging repair

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2276204A (en) * 1940-01-02 1942-03-10 Kilgore Dev Corp Chemical light filter
DE2728242A1 (en) * 1977-06-23 1979-01-11 Henkel Kgaa COSMETIC LIGHT PROTECTION AGENTS FOR THE UV-A AREA
US6121243A (en) * 1994-12-13 2000-09-19 Beiersdorf Ag Treatment of skin with a formulation comprising alpha-glucosyl rutin and one or more cinnamic acid derivatives
US20080152603A1 (en) * 2005-04-19 2008-06-26 Thomas Rudolph Antioxidants

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2276204A (en) * 1940-01-02 1942-03-10 Kilgore Dev Corp Chemical light filter
DE2728242A1 (en) * 1977-06-23 1979-01-11 Henkel Kgaa COSMETIC LIGHT PROTECTION AGENTS FOR THE UV-A AREA
US6121243A (en) * 1994-12-13 2000-09-19 Beiersdorf Ag Treatment of skin with a formulation comprising alpha-glucosyl rutin and one or more cinnamic acid derivatives
US20080152603A1 (en) * 2005-04-19 2008-06-26 Thomas Rudolph Antioxidants

Also Published As

Publication number Publication date
KR20110012148A (en) 2011-02-09
WO2011014025A2 (en) 2011-02-03

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