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WO2011008675A3 - Catecholamine compounds, compositions, and formulations, and methods of using the same - Google Patents

Catecholamine compounds, compositions, and formulations, and methods of using the same Download PDF

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Publication number
WO2011008675A3
WO2011008675A3 PCT/US2010/041666 US2010041666W WO2011008675A3 WO 2011008675 A3 WO2011008675 A3 WO 2011008675A3 US 2010041666 W US2010041666 W US 2010041666W WO 2011008675 A3 WO2011008675 A3 WO 2011008675A3
Authority
WO
WIPO (PCT)
Prior art keywords
formulations
compositions
methods
same
compounds
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/US2010/041666
Other languages
French (fr)
Other versions
WO2011008675A2 (en
Inventor
Andrew R. Chadeayne
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of WO2011008675A2 publication Critical patent/WO2011008675A2/en
Publication of WO2011008675A3 publication Critical patent/WO2011008675A3/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles
    • C07C255/01—Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms
    • C07C255/32—Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms having cyano groups bound to acyclic carbon atoms of a carbon skeleton containing at least one six-membered aromatic ring
    • C07C255/41—Carboxylic acid nitriles having cyano groups bound to acyclic carbon atoms having cyano groups bound to acyclic carbon atoms of a carbon skeleton containing at least one six-membered aromatic ring the carbon skeleton being further substituted by carboxyl groups, other than cyano groups
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/44—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D317/46—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D319/00—Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D319/10—1,4-Dioxanes; Hydrogenated 1,4-dioxanes
    • C07D319/14—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems
    • C07D319/16—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D319/20—1,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems condensed with one six-membered ring with substituents attached to the hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D321/00—Heterocyclic compounds containing rings having two oxygen atoms as the only ring hetero atoms, not provided for by groups C07D317/00 - C07D319/00
    • C07D321/02—Seven-membered rings
    • C07D321/10—Seven-membered rings condensed with carbocyclic rings or ring systems

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Psychology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

The invention relates to catecholamine compounds, compositions, and formulations comprising those compounds, and methods of treating Parkinson's disease with those compounds, compositions, and/or formulations.
PCT/US2010/041666 2009-07-15 2010-07-12 Catecholamine compounds, compositions, and formulations, and methods of using the same Ceased WO2011008675A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US22581109P 2009-07-15 2009-07-15
US61/225,811 2009-07-15

Publications (2)

Publication Number Publication Date
WO2011008675A2 WO2011008675A2 (en) 2011-01-20
WO2011008675A3 true WO2011008675A3 (en) 2011-04-28

Family

ID=43450111

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2010/041666 Ceased WO2011008675A2 (en) 2009-07-15 2010-07-12 Catecholamine compounds, compositions, and formulations, and methods of using the same

Country Status (1)

Country Link
WO (1) WO2011008675A2 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX386251B (en) * 2013-03-15 2025-03-18 Techfields Pharma Co Ltd NOVEL HIGH-PENETRATION DRUGS AND THEIR COMPOSITIONS FOR THE TREATMENT OF PARKINSON'S DISEASES.
KR102369427B1 (en) * 2013-12-05 2022-03-03 가부시키가이샤 아데카 Novel compound and composition containing novel compound
CN105061259A (en) * 2015-08-25 2015-11-18 重庆植恩药业有限公司 Preparing method for entacapone A-type crystals

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005063693A1 (en) * 2003-12-29 2005-07-14 Suven Life Sciences Ltd Improved process for the preparation of entacapone
WO2006064296A1 (en) * 2004-12-15 2006-06-22 Alkaloida Kutato Es Fejlesztö Kft Process for the preparation of (e)-n,n-diethyl-2-cyano-3(3,4-dihydroxy-5-nitro-phenyl)-acrylamide in stable polymorphic form and intermediates of the process
US20080103191A1 (en) * 2006-06-16 2008-05-01 Klaus Hansen Entacapone-derivatives
US20080146829A1 (en) * 2006-12-19 2008-06-19 Dipharma Francis S.R.L. Process for the preparation of entacapone
WO2008119793A1 (en) * 2007-04-02 2008-10-09 Esteve Química, S.A. Process for the preparation of entacapone and intermediates thereof

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005063693A1 (en) * 2003-12-29 2005-07-14 Suven Life Sciences Ltd Improved process for the preparation of entacapone
WO2006064296A1 (en) * 2004-12-15 2006-06-22 Alkaloida Kutato Es Fejlesztö Kft Process for the preparation of (e)-n,n-diethyl-2-cyano-3(3,4-dihydroxy-5-nitro-phenyl)-acrylamide in stable polymorphic form and intermediates of the process
US20080103191A1 (en) * 2006-06-16 2008-05-01 Klaus Hansen Entacapone-derivatives
US20080146829A1 (en) * 2006-12-19 2008-06-19 Dipharma Francis S.R.L. Process for the preparation of entacapone
WO2008119793A1 (en) * 2007-04-02 2008-10-09 Esteve Química, S.A. Process for the preparation of entacapone and intermediates thereof

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
LEPPANEN, J. ET AL.: "Structural studies of acyl esters of entacapone", JOURNAL OF MOLECULAR STRUCTURE, vol. 562, no. 1-3, 2001, pages 129 - 135, XP002300342, DOI: doi:10.1016/S0022-2860(00)00859-0 *
SHETTY, S. K. ET AL.: "Stress Degradation Behavior of Entacapone and Development of LC Stability-Indicating Related Substances and Assay Method", CHROMATOGRAPHIA, vol. 69, no. 11/12, 24 June 2009 (2009-06-24), pages 1189 - 1199 *

Also Published As

Publication number Publication date
WO2011008675A2 (en) 2011-01-20

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