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WO2011091328A3 - Méthodes et compositions améliorées pour la détermination du statut pathogène d'agents infectieux - Google Patents

Méthodes et compositions améliorées pour la détermination du statut pathogène d'agents infectieux Download PDF

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Publication number
WO2011091328A3
WO2011091328A3 PCT/US2011/022161 US2011022161W WO2011091328A3 WO 2011091328 A3 WO2011091328 A3 WO 2011091328A3 US 2011022161 W US2011022161 W US 2011022161W WO 2011091328 A3 WO2011091328 A3 WO 2011091328A3
Authority
WO
WIPO (PCT)
Prior art keywords
infectious agents
compositions
determining
present
methods
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/US2011/022161
Other languages
English (en)
Other versions
WO2011091328A2 (fr
WO2011091328A8 (fr
Inventor
Matthew C. Mulvey
Leo Einck
Katherine Sacksteder
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sequella Inc
Original Assignee
Sequella Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sequella Inc filed Critical Sequella Inc
Priority to EP11735280.7A priority Critical patent/EP2526208A4/fr
Priority to CA2825187A priority patent/CA2825187A1/fr
Publication of WO2011091328A2 publication Critical patent/WO2011091328A2/fr
Publication of WO2011091328A8 publication Critical patent/WO2011091328A8/fr
Anticipated expiration legal-status Critical
Publication of WO2011091328A3 publication Critical patent/WO2011091328A3/fr
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/74—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6888—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms
    • C12Q1/689—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms for bacteria
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/156—Polymorphic or mutational markers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Plant Pathology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

La présente invention a pour objet des méthodes et des compositions pour une détection améliorée des agents infectieux et des microbes. En particulier, la présente invention concerne de nouvelles méthodes de détection des agents infectieux, de fourniture d'informations au sujet du statut de viabilité de tels agents infectieux et de détermination de la sensibilité aux médicaments. Dans certains modes de réalisation, la présente invention utilise des techniques impliquant une identification microbienne basée sur une amplification d'acides nucléiques conjointement avec une détection biologique à base de phages de la résistance aux médicaments. Les méthodes selon la présente invention sont appropriées pour tous les microbes et les agents infectieux, y compris les agents bactériens tels que les mycobactéries.
PCT/US2011/022161 2010-01-21 2011-01-21 Méthodes et compositions améliorées pour la détermination du statut pathogène d'agents infectieux Ceased WO2011091328A2 (fr)

Priority Applications (2)

Application Number Priority Date Filing Date Title
EP11735280.7A EP2526208A4 (fr) 2010-01-21 2011-01-21 Méthodes et compositions améliorées pour la détermination du statut pathogène d'agents infectieux
CA2825187A CA2825187A1 (fr) 2010-01-21 2011-01-21 Methodes et compositions ameliorees pour la determination du statut pathogene d'agents infectieux

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US29705610P 2010-01-21 2010-01-21
US61/297,056 2010-01-21
US37164610P 2010-08-06 2010-08-06
US61/371,646 2010-08-06

Publications (3)

Publication Number Publication Date
WO2011091328A2 WO2011091328A2 (fr) 2011-07-28
WO2011091328A8 WO2011091328A8 (fr) 2012-03-01
WO2011091328A3 true WO2011091328A3 (fr) 2013-03-14

Family

ID=44307626

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2011/022161 Ceased WO2011091328A2 (fr) 2010-01-21 2011-01-21 Méthodes et compositions améliorées pour la détermination du statut pathogène d'agents infectieux

Country Status (3)

Country Link
EP (1) EP2526208A4 (fr)
CA (1) CA2825187A1 (fr)
WO (1) WO2011091328A2 (fr)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104962560B (zh) * 2015-06-16 2017-07-21 湖南大学 一种检测日本血吸虫卵的核酸适配体及其在制备检测制剂中的应用

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6833135B1 (en) * 1997-08-06 2004-12-21 Laboratorio Medinfar Produtos Farmaceuticos, Lda. DNA integration into “Mycobacterium spp.” genome by trans-complementation using a site-specific integration system
WO2008131230A1 (fr) * 2007-04-18 2008-10-30 Cornell University Procédé et appareil de détection de micro-organisme
US20090047658A1 (en) * 2007-04-05 2009-02-19 Mulvey Matthew C Methods and compositions for determining the pathogenic status of infectious agents
US20090155768A1 (en) * 2004-04-07 2009-06-18 Dean Scholl Reporter plasmid phage packaging system for detection of bacteria

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100454585B1 (ko) * 2001-10-09 2004-11-02 주식회사 에스제이하이테크 마이코박테리아의 균주 감별, 결핵균의 스트레인 감별과항생제 내성을 검출하기 위한 프로브를 포함하는마이크로어레이와 이를 이용한 검출 방법 및 진단 키트

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6833135B1 (en) * 1997-08-06 2004-12-21 Laboratorio Medinfar Produtos Farmaceuticos, Lda. DNA integration into “Mycobacterium spp.” genome by trans-complementation using a site-specific integration system
US20090155768A1 (en) * 2004-04-07 2009-06-18 Dean Scholl Reporter plasmid phage packaging system for detection of bacteria
US20090047658A1 (en) * 2007-04-05 2009-02-19 Mulvey Matthew C Methods and compositions for determining the pathogenic status of infectious agents
WO2008131230A1 (fr) * 2007-04-18 2008-10-30 Cornell University Procédé et appareil de détection de micro-organisme

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
See also references of EP2526208A4 *
SERGANOV ET AL.: "Ribozymes, riboswitches and beyond: regulation of gene expression without proteins", NATURE REVIEWS GENETICS, vol. 8, 11 September 2007 (2007-09-11), pages 776 - 790, XP055107979 *
STANLEY ET AL.: "Development of a New, Combined Rapid Method Using Phage and PCR for Detection and Identification of Viable Mycobacterium paratuberculosis Bacteria within 48 Hours", APPLIED AND ENVIRONMENTAL MICROBIOLOGY, vol. 73, 26 January 2007 (2007-01-26), pages 1851 - 1857, XP055107978 *

Also Published As

Publication number Publication date
EP2526208A4 (fr) 2014-01-15
EP2526208A2 (fr) 2012-11-28
CA2825187A1 (fr) 2011-07-28
WO2011091328A2 (fr) 2011-07-28
WO2011091328A8 (fr) 2012-03-01

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