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WO2010132496A1 - Système, procédé et produit de nettoyage, de blanchiment et d'amélioration de surface thérapeutique utilisant des ondes soniques ou ultrasoniques ou des flux acoustiques - Google Patents

Système, procédé et produit de nettoyage, de blanchiment et d'amélioration de surface thérapeutique utilisant des ondes soniques ou ultrasoniques ou des flux acoustiques Download PDF

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Publication number
WO2010132496A1
WO2010132496A1 PCT/US2010/034440 US2010034440W WO2010132496A1 WO 2010132496 A1 WO2010132496 A1 WO 2010132496A1 US 2010034440 W US2010034440 W US 2010034440W WO 2010132496 A1 WO2010132496 A1 WO 2010132496A1
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WIPO (PCT)
Prior art keywords
omni
containment chamber
energy source
sonic energy
active ingredient
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PCT/US2010/034440
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English (en)
Inventor
Michael Florman
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Individual
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Individual
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Publication of WO2010132496A1 publication Critical patent/WO2010132496A1/fr
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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61C—DENTISTRY; APPARATUS OR METHODS FOR ORAL OR DENTAL HYGIENE
    • A61C17/00—Devices for cleaning, polishing, rinsing or drying teeth, teeth cavities or prostheses; Saliva removers; Dental appliances for receiving spittle
    • A61C17/16—Power-driven cleaning or polishing devices
    • A61C17/20—Power-driven cleaning or polishing devices using ultrasonics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61C—DENTISTRY; APPARATUS OR METHODS FOR ORAL OR DENTAL HYGIENE
    • A61C17/00—Devices for cleaning, polishing, rinsing or drying teeth, teeth cavities or prostheses; Saliva removers; Dental appliances for receiving spittle
    • A61C17/16—Power-driven cleaning or polishing devices
    • A61C17/22—Power-driven cleaning or polishing devices with brushes, cushions, cups, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61C—DENTISTRY; APPARATUS OR METHODS FOR ORAL OR DENTAL HYGIENE
    • A61C19/00—Dental auxiliary appliances
    • A61C19/06—Implements for therapeutic treatment
    • A61C19/063—Medicament applicators for teeth or gums, e.g. treatment with fluorides

Definitions

  • the present invention generally relates to devices, processes product kits, and compositions for using sonic or ultrasonic waves to activate and improve the uptake, delivery, and efficacy of cleaning agents, whitening agents or therapeutic agents (or medicaments) on hard and soft surfaces.
  • This invention describes a system, a method, and process for cleaning and whitening teeth and for therapeutic enhancement of teeth.
  • the present invention generally relates to devices, processes product kits, and compositions for using sonic or ultrasonic waves to activate and improve the uptake, delivery, and efficacy of cleaning agents, whitening agents or therapeutic agents (or medicaments) on hard and soft surfaces.
  • This invention describes a system, a method, and process for cleaning and whitening teeth and for therapeutic enhancement of teeth.
  • omni-sonic means the entire range of energy and wavelengths, without limitation, associated with sonic and ultrasonic waves.
  • the term enhance, enhancing or any derivations thereof means any and all activity, without limitation, to activate, increase the level and depth of penetration or absorption of, and/or improve the efficacy of, cleaning agents, whitening agents or therapeutic agents into hard or soft surfaces.
  • the term active ingredient means cleaning agents, whitening agents or therapeutic agents (or medicaments).
  • the term contact surfaces include both hard surfaces and soft surfaces, in particular, oral surfaces such as the teeth, gums, skin and bones. The oral surface can include human oral surfaces as well as other animal oral surfaces.
  • Ultrasonic devices have been used over the last decades as cleaning instruments for various items, including mechanical parts, and jewelry. Many ultrasonic cleaning baths are used to hold the cleaning liquid and object needing to be cleaned. This container creates a fixed environment in which the ultrasonic waves can enhance the efficacy of the cleaning agent. Dentists have used ultrasonic waves to remove build-up of tartar from teeth surfaces and remove stains. Ultrasonic teeth cleaning devices have been disclosed in, for example Kruse, et al., US Patent No. 3,375,820 and Robinson, US Patent No. 3,645,256, which are incorporated in their entirety by reference. Ultrasonic sealers incorporate a sonitrode and an ultrasonic source to physically contact the tooth and knock off deposits.
  • ultrasonic dental sealer examples include Regere, et al., US Patent Application Publication No. 2008/0293008, and Atkin, et al., US Patent No. 7,217,128, each of which are incorporated herein in their entirety by reference.
  • Ultrasonic waves have also been used to enhance the absorption of medicament via phonophoresis.
  • ultrasonic shaping devices have been used by dentists as disclosed in Huguenin, et al., US Patent No. 7,172,420, which is incorporated herein in its entirety by reference.
  • the present invention generally relates to devices, processes product kits, and compositions for using sonic or ultrasonic waves to activate and improve the uptake, delivery, and efficacy of cleaning agents, whitening agents or therapeutic agents (or medicaments) on hard and soft surfaces.
  • This invention describes a system, a method, and process for cleaning and whitening teeth and for therapeutic enhancement of teeth.
  • the benefits of active ingredients can be enhanced by increasing the level and depth of penetration into hard or soft surfaces.
  • a hard surface would be the human tooth.
  • the human gum, skin or bone tissue is an example of a soft surface.
  • the omni-sonic waves impart omni-sonic energy to the active ingredient, whether it is a cleaning, whitening or therapeutic agent, to enhance its effectiveness by increasing the molecular activity of the agent.
  • the increased molecular activity of the active ingredient activates, increases the level and depth of penetration or absorption of, and/or increases the efficacy of the active ingredient into hard or soft surfaces.
  • a containment chamber is provided.
  • this invention can be applied to enhance the absorption of various medicaments into both the hard and soft tissues of the oro-pharyngeal cavity.
  • the present invention includes an omni-sonic energy source, such as a sonitrode tip, and a containment chamber, that encloses the omni-sonic energy source and at least a portion of the active ingredient, and that works to direct the active ingredient to a specified surface area while simultaneously acting as a splatter guard.
  • This containment chamber provides an environment where omni-sonic waves can form and enhance the active ingredient.
  • the laws of Mass Cleaning Action also state that cleaning agents increase their ability to function when agitation is increased.
  • the present invention relates to a system for enhancing contact surfaces comprising: an omni-sonic energy source, wherein the omni-sonic energy source is activated by a power source; an omni-sonic energy source tip having a length and a width and comprising: a working end at a distal end of the length of the omni-sonic energy source tip; and a connecting end at a proximal end of the length of the omni-sonic energy source tip and connected to the omni- sonic energy source; an active ingredient; and a containment chamber in which at least a portion of the omni-sonic energy source tip is located and comprising: a contact end at a distal end of the containment chamber; and a connecting end at a proximal end of the containment chamber and walls physically connected to the connecting end, wherein the containment chamber contains at least a portion of the active ingredient when the omni-sonic energy source is activated, and wherein omni- sonic energy source provides
  • the present invention relates to a method of enhancing a contact surface comprising: applying an active ingredient; containing and directing the active ingredient to an area of the contact surface; creating omni- sonic waves, in the active ingredient, having an omni-sonic frequency and an amplitude.
  • the present invention relates to a process for removing stains on a contact surface comprising: selecting a stained portion of the contact surface; applying an effective amount of an active ingredient to the stained portion of the contact surface; containing and directing the active ingredient and a working end of an omni-sonic energy source tip to said stained portion of the contact surface; and activating the working end of the omni-sonic energy source tip imparting omni-sonic waves to the active ingredient.
  • the present invention relates to a containment chamber attachment comprising: an opening at a contact end; a connecting end opposing the contact end, said connecting end including a passage to permit a working end of an omni-sonic energy source tip be placed into the containment chamber; and walls defining the opening at the contact end and connected to the connecting end.
  • the present invention relates to a containment chamber attachment comprising: a top wall having a width and a length; two opposing side walls connected to at least a portion of the top side; a contact end connected to the top wall and the two side walls; an opening opposing the top wall; a connecting end opposing the contact end; and said connecting end including a passage to permit a working end of an omni-sonic energy source tip to be placed into the containment chamber attachment and an attachment to connect the containment chamber attachment to an omni-sonic dental apparatus.
  • the present invention relates to a method of enhancing a contact surface comprising: applying an active ingredient to at least one area; containing and directing the active ingredient to an area of the contact surface; covering the at least one area with a film; creating omni-sonic waves, in the active ingredient, having an omni-sonic frequency and an amplitude.
  • the invention combines the containment chamber, omni-sonic energy source, and active ingredient. It encompasses these items into a unique environment that allows for increased efficacy and absorption of cleaning and whitening agents and therapeutics. Without the unique environment created by this invention, cleaning, whitening and therapeutic agents would leave the surface target area due to eddies created by the omni-sonic waves, decreasing or eliminating the agents' effectiveness against the surface.
  • Figure 1 shows a prior art piezoelectric omni-sonic energy source tip device with handle, power source and foot pedal.
  • Figure 2 shows a prior art magnetostrictive omni-sonic energy source tip sonotrode device with handle, power source and foot pedal.
  • Figure 3 illustrates a prior art sonotrode used on a tooth.
  • Figure 4 illustrates a close-up of a splatter of the active ingredient caused by a prior art sonotrode being used with an active ingredient on a tooth.
  • Figure 5A illustrates a working end of an omni-sonic source tip having bristle fibers.
  • Figure 5B illustrates a working end of an omni-sonic source tip having perforations.
  • Figure 5C illustrates a working end of an omni-sonic source tip having an uneven surface.
  • Figure 5D illustrates a working end of an omni-sonic source tip having a detachable sticker.
  • Figure 6A shows side view of a containment chamber of the present invention and a separate omni-sonic source tip and handle.
  • Figure 6B shows a side view of the omni-sonic source tip and handle structure centered within the containment chamber.
  • Figure 6C shows a bottom view of the omni-sonic source tip and handle structure centered within the containment chamber.
  • Figure 7A illustrates a side view of the containment chamber in which the contact end is circular in shape and omni-sonic source tip is centered within the containment chamber.
  • Figure 7B illustrates a view of a containment chamber which has a three sided shape as shown at the contact end of the containment chamber.
  • Figure 7C illustrates another view of a containment chamber which has a four sided shape as shown at the contact end of the containment chamber.
  • Figure 8A shows a gasket seal ring for the contact end of the containment chamber.
  • Figure 8B shows a slot in the opening of the contact end of the containment chamber to accept the gasket seal ring.
  • Figure 8C shows the gasket ring inserted in the slot in the opening of the contact end of the containment chamber to accept the gasket seal ring.
  • Figure 8D shows a gasket disk which can be permanently attached to or be attachable to the working end of the omni-sonic energy source tip, not shown.
  • Figure 8E shows 465451.01 .123400.0001 the contact end of the containment chamber into which the gasket disk is inserted.
  • Figure 8F shows the gasket disk inserted into the contacted end of the containment chamber.
  • Figure 9 shows the contact end of a containment chamber with the gasket ring inserted providing an interface between the containment chamber and the surface to be enhanced.
  • Figure 10A illustrates the distance between the working end of an omni-sonic energy source tip and the contact end of the containment chamber as shown from the end view of the working end of the omni-sonic source tip in the opening at the contact end of the containment chamber.
  • Figure 10B illustrates the distance between the working end of an omni-sonic energy source and the contact end of the containment chamber as shown in a side view of the contact end of the containment chamber.
  • Figure 1 1A shows a port in the containment chamber either for importing an active ingredient or other solution into the containment chamber or for extraction of residue from the containment chamber.
  • Figure 11 B shows a second port in the containment chamber either for importing an active ingredient or for extraction of residue.
  • Figure 1 1 C shows a side view of a containment chamber with two ports, one for delivering an active ingredient or other solution into the containment chamber and one for extraction of residue from the containment chamber and an optional storage container attached by way of a tube to the port for delivering active ingredient or other solution to the containment chamber.
  • Figure 1 1 D shows a partial side view of a containment chamber with the port for extraction of residue from the containment chamber and a device for restricting or stopping the residue from being extracted by a vacuum source from the containment chamber through a tube attached to the port.
  • Figure 12 shows the contact end of the containment chamber and the working end of the omni-sonic energy source tip with active ingredient contained within the containment chamber.
  • Figure 13 shows a side view of two parts, a containment chamber and a handle for an omni-sonic energy source, with the containment chamber part having a connecting lip and the handle part having a connecting extension for easy assembly of the two parts.
  • Figure 14A illustrates a side view of another embodiment of two parts of a containment chamber.
  • Figure 14B illustrates a side view of a whole containment chamber assembled from the two parts of the containment chamber and assembled around the omni-sonic energy source tip.
  • Figure 15A shows a side view of a containment chamber having serrations for finger gripping and omni-sonic energy source structure with a O-ring on the omni-sonic energy source tip for connecting the omni-sonic energy source handle to the containment chamber.
  • Figure 15B shows a side view of the omni-sonic energy source tip inserted in the containment chamber with the O-ring inserted at the connecting end of the containment chamber for connecting to the handle of the omni-sonic energy source.
  • Figure 16A illustrates a top view of the containment chamber as seen from the connecting end of the containment chamber with the gasket disk inserted into the connecting end of the containment chamber and with three slits meeting in the center of the gasket disk to allow the omni-sonic energy source tip to be inserted through the slits in the gasket disk.
  • Figure 16B illustrates a side view of the containment chamber with the gasket disk in place at the connecting end of the containment chamber.
  • Figure 17 illustrates the top view of the containment chamber having the gasket disk with three slits as positioned in contact with a tooth.
  • Figure 18A illustrates a top view of the containment chamber as seen from the connecting end of the containment chamber with the gasket disk inserted into the connecting end of the containment chamber and with a single slit crossing most of the diameter of the gasket disk to allow the omni-sonic energy source tip to be inserted through the slits in the gasket disk.
  • Figure 18B illustrates a side view of the containment chamber with the gasket disk in place at the connecting end of the containment chamber and a stop disk attached to the omni-sonic energy source tip.
  • Figure 19 illustrates omni-sonic energy source tip with a threading mechanism and an adjustable stop disk.
  • Figure 20 shows a method of enhancing a contact surface.
  • Figure 21 shows further aspects of a method to enhance a contact surface by using an on omni-sonic energy source tip to impart omni-sonic energy.
  • Figure 22 shows further aspects of a method to enhance a contact surface by applying an effective amount of active ingredient to a contact surface.
  • Figure 23 shows even further aspects of a method to enhance a contact surface by applying an effective amount of active ingredient to a contact surface.
  • Figure 24 shows even further aspects of a method to enhance a contact surface by containing and directing the active ingredient at or on the oral surface within a confined space of a containment chamber.
  • Figure 25 shows a process for removing stains on a contact surface.
  • Figure 26 shows further aspects of a process for removing stains on a contact surface by applying an effective amount of an active ingredient to the stained portion of the contact surface.
  • Figure 27 shows a process for delivery of therapeutic agents.
  • the present invention generally relates to devices, processes product kits, and compositions for using sonic or ultrasonic waves to activate and improve the uptake, delivery, and efficacy of cleaning agents, whitening agents or therapeutic agents (or medicaments) on hard and soft surfaces.
  • This invention describes a system, a method, and process for cleaning and whitening teeth and for therapeutic enhancement of teeth.
  • omni-sonic means the entire range of energy and wavelengths, without limitation, associated with sonic and ultrasonic waves.
  • the term enhance, enhancing or any derivations thereof means any and all activity, without limitation, to activate, increase the level and depth of penetration or absorption of, and/or improve the efficacy of, cleaning agents, whitening agents or therapeutic agents into hard or soft surfaces.
  • the term active ingredient means cleaning agents, whitening agents or therapeutic agents (or medicaments).
  • the term contact surfaces include both hard surfaces and soft surfaces, in particular, oral surfaces such as the teeth, gums, skin and bones. The oral surface can include human oral surfaces as well as other animal oral surfaces.
  • omni-sonic energy or waves can be used.
  • An example of a hard surface includes a human tooth and examples of soft surfaces include human gums, skin or bones.
  • Omni-sonic energy or waves can be generated from any suitable source, as known to those skilled in the art.
  • the prior art omni-sonic energy source structures are piezoelectric 100 or magnetorestrictive 200, or hybrids thereof, comprising an acoustic amplifier, typically called an acoustic horn or acoustic transducer, or sonotrode.
  • the system of the present invention comprises an omni- sonic energy source tip, 101 and 201 , respectively, connected to an omni-sonic energy source 102 or 202, respectively.
  • the omni-sonic energy source 102 or 202 is provided a handle 103 for manual manipulation and a power source 105 as a source of power.
  • the power may include electrical power, pneumatic power and mechanical power. Electrical power may include a battery and a plug-in type to an electrical outlet, not shown.
  • the power source 105 is connected 107 to the omni-sonic energy source 102 or 202. Further, the power source 105 may optionally also include a set of tubes, not shown, for delivery of active ingredient 401 to the omni-sonic energy source tip 101 or 201 , as known to those skilled in the art.
  • the power source 105 may also operate as an omni-sonic frequency generator.
  • the omni-sonic energy source 102 or 202 further comprises a mechanism to vary the omni-sonic frequency of the omni-sonic waves, to vary the amplitude of the omni- sonic waves, or both.
  • a mechanism may include a foot pedal device 104, a switch or dial, not shown, on said mechanism, or a button, switch or a trigger, not shown, on the handle 102.
  • Said mechanism can be combined with or connected to the power source 105, for example, in the case of the foot pedal device 106.
  • the omni-sonic energy source tip 101 may be detachable from and re- attachable to the omni-sonic energy source 102, through a connecting device 109, or the omni-sonic energy source tip 201 may be part of a unitary body with the omni- sonic energy source 102.
  • the system may operate within the entire omni-sonic range, or portions thereof, and is selectable to a specific frequency or range of frequencies and power and delivers a predetermined amplitude at the omni-sonic energy source tip 101 or 201 or, more particularly, the working end of the omni-sonic energy source tip 108 or 208.
  • a unique system is created that focuses and directs the omni-sonic energy and re-circulates the active ingredient 401 being supplied, preventing it from washing away or moving away from the desired area of application.
  • This containment chamber 601 or 701 can be called a splatter guard, since it simultaneously acts to prevent the active ingredient 401 from being sprayed about within the oral cavity.
  • Generally centered within the containment chamber 601 or 701 sits the omni-sonic energy source tip 101 or 201 , as shown in Figures 6B and 6C or Figure 7A.
  • Omni-sonic energy source tip 101 or 201 designs can vary, and comprise of different shapes which can improve the cleaning, whitening or therapeutic efficacy or penetration.
  • the working end 108 or 208 of the omni-sonic energy source tip 101 or 201 may also take different shapes, non-limiting examples being, a working end having bristles as shown in Fig 5A, having perforations as shown in Figure 5B, having an uneven surface acting as an abrasive as shown in Figure 5C, or having a detachable sticker or attachable sleeve that has a surface that may include abrasives as shown in Figure 5D.
  • the working end 108 or 208 of the omni-sonic energy source tip 101 or 201 may be impregnated with active ingredients 401 , when placed in contact with the contact surface 301 .
  • the system for enhancing hard or soft surfaces of the present invention comprises an omni-sonic source 102 or 202, a handle 103, an omni-sonic energy source tip 101 or 201 having a length and a width and comprising a working end 108 or 208 at a distal end of the length of the omni-sonic energy source tip 101 or 201 and a connecting end 1 10 or 210 at a proximal end of the length of the omni-sonic energy source tip 101 or 201 and connected to the omni- sonic energy source 102 or 202, an active ingredient 401 , and a containment chamber 601 or 701 , in which the omni-sonic energy source tip 101 or 201 is located, and comprising a contact end 602 or 702 at a distal end
  • an Acteon, PMax XS is an example of a piezoelectric omni-sonic energy source and a Dentsply, Cavitron Plus is an example of a magnetorestrictive omni-sonic energy source, both of which are incorporated herein by reference.
  • the containment chamber 601 or 701 can range from 2 mm to 10 mm, as measured across an opening of containment chamber 601 or 701 at the contact end 602 or 702.
  • the size of the contact end 602 or 702 of the containment chamber 601 or 701 may vary depending on whether the contact end 602 or 702 is submerged into the active ingredient 401 , or contacting the active ingredient 401 with no contact surface 301 contact.
  • the containment chamber 601 or 701 can be made up of any material, including but not limited to metals, plastics, alloys, composites, resins, fibers, paper, wax, or other moldable, injectable, carvable, or, in particular, materials that can be formed.
  • a gasket ring seal 801 as shown in Figure 8A can be applied to reduce the interface between the contact end 602 or 702 of the containment chamber 601 or 701 and the contact surface 301 as shown in Figure 9.
  • a gasket disk 805 can be inserted into the opening at the contact end of the containment chamber, as shown in Figures 8D, 8E and 8F. Rubber, silicone, or other materials used to fabricate gaskets seal rings or gasket disks can be used. Further, material of the same material as the containment chamber may also be used.
  • the shape of the gasket seal ring or gasket disk conforms the opening at the contact end of the containment chamber.
  • the omni-sonic energy source tips 101 and 210 and containment chambers 601 and 701 are meant to be either disposable or autoclavable depending on the desired method and material being employed. Unit dose or single use parts are preferred.
  • Omni-sonic energy source tips 101 or 201 can be designed to fit within the containment chamber 601 or 701 and have a minimum distance of .005 mm, "A" as shown in Figures 10A and 10B, from working end 108 or 208 of the omni-sonic energy source tip 101 or 201 and the edge of contact end 602 or 702 of the containment chamber 601 or 701.
  • the working end 108 or 208 of the omni-sonic energy source tip 101 or 201 may be as far as 7 mm from the edge of contact end 602 or 702 of the containment chamber 601 or 701 .
  • the omni-sonic energy source tip 101 or 201 material is chosen in order to have the desired omni-sonic properties and also be compatible with the chemistry being used in the particular application. Suitable materials include, but are not limited to, titanium, aluminum and steel, preferably hardened steel. Other materials can be used, including, but no limited to, plastic, carbon composite materials or a combination metal/plastic or metal/carbon composite. Preferably, a material softer that the human tooth structure is attached to the omni-sonic energy source tip, allowing for contact of the tip to the tooth without harmful cutting of the tooth surface.
  • the omni-sonic energy source 102 or 202 oscillates at a frequency range, which is translated to the omni-sonic energy source tip 101 or 201 , of from 100 Hz to about 40,000 kHz, more preferably from about 100 Hz to about 30,000 kHz, even more preferably from about 150 Hz to about 20000 kHz, but not limited thereto.
  • a port 1 101 can be added to the containment chamber 601 to allow for delivery of active ingredients 401 , and/or a second port 1 102, as shown in Figure 1 1 B, can be added as an extracting port to be attached to a suction unit, not shown, for the extraction of residue.
  • port 1 103 for delivery of active ingredients 401 and/or port 1 104 for extracting of residue 1 106 can be added to containment chamber 701 , as shown in Figure 1 1 C.
  • a device to restrict or halt extraction 1105 such as a finger spring pinch, can be added to the extracting ports 1 102 or 1 104, as shown in Figure 1 1 D.
  • the present invention includes omni-sonically enhanced active ingredients 1201 that are constrained by the containment chamber 601 or 701 .
  • the active ingredients 1201 include cleaning or whitening agents which comprise: cleaning or whitening compositions or agents, preferably a liquid or gel, selected from groups consisting of enzymes, bleach or peroxide products, catalyst and or mixtures thereof.
  • the active ingredients are present in an effective amount, more preferably from about 0.0001 % to about 90% by weight, even more preferably from about 0.001 % to about 70% by weight, even more preferably still from about 0.005% to about 40% by weight, even more preferably still from about 0.01 % to about 30% by weight by weight.
  • the active ingredients 401 or 1201 deliver increased cleaning performance when they are confined within the containment chamber 601 or 701 in conjunction with omni-sonic energy.
  • These active ingredients 401 or 1201 can comprise additional additives and these are explained in greater detail hereafter.
  • the active ingredients 401 or 1201 also include therapeutic agents.
  • therapeutic agents can comprise: therapeutic compositions or agents, preferably a liquid or gel, selected from groups consisting of antibiotics, anticaries, antisensitivity, antihalitosis, antiviral, antiaphthous, analgesic, dentinal tubule sealing or obstructing, remineralization, but not limited to any dental therapeutic or oral- pharyngial therapeutic.
  • therapeutic compositions or agents preferably a liquid or gel, selected from groups consisting of antibiotics, anticaries, antisensitivity, antihalitosis, antiviral, antiaphthous, analgesic, dentinal tubule sealing or obstructing, remineralization, but not limited to any dental therapeutic or oral- pharyngial therapeutic.
  • Omni-sonically enhanced therapeutics agents are present in compositions in an effective amount, more preferably from about 0.0001 % to about 99% by weight, even more preferably from about 0.001 % to about 70% by weight, even more preferably still from about 0.005% to about 40% by weight, even more preferably still from about 0.01 % to about 30% by weight. It has been surprisingly found that these omni-sonically enhanced therapeutic agents can be delivered deeper in conjunction with omni-sonic energy. These therapeutic compositions can comprise additional additives and these are explained in greater detail hereafter.
  • the connecting end 703 of containment chamber 701 can include a connecting lip 1301 which can be attached to a connecting extension 1302 of the omni-sonic energy source 102, not shown, or the handle 103, such that the omni-sonic energy source tip 101 , not shown, which is attached to the omni-sonic energy source 102, can be inserted into the containment chamber 701 .
  • the containment chamber 701 can be comprised of two containment chamber halves 1401 and 1402, that can be joined together around the omni-sonic energy source tip 101 , as shown in Figure 14B.
  • the connecting end 703 of the containment chamber 701 can be connected to the omni-sonic energy source 102, not shown, or handle 103 by means of an O-ring 1501 , as shown in Figure 15A.
  • the O-ring is used to connect the omni-sonic energy source 102 or handle 103.
  • the connecting mechanisms described herein are non-limiting and any other connecting mechanisms may be used.
  • the containment chamber 701 has a slitted disk 1601 with three slits 1602 located at the connecting end 703 of the containment chamber 701 .
  • the slitted disk 1602 is used to connect the containment chamber 701 to the omni-sonic energy source tip 101 , not shown.
  • the contact end 702 of the containment chamber 701 is placed in contact with contact surface 301 as shown in Figure 17.
  • the slitted disk 1801 comprises a single slit 1804 creating two halves 1802 and 1803 of the slitted disk 1801 .
  • the slitted disk 1801 is located at the connecting end 703 of the containment chamber 701 .
  • the slitted disk 1801 is used to connect the containment chamber 701 to the omni-sonic energy source tip 101 .
  • a stop disk 1805 is attached to omni-sonic energy source tip 101 at the appropriate location such that the working end 103 of the omni-sonic energy source tip 101 is in or near the same plane as the contact end 703 of the containment chamber 701.
  • another embodiment of the stop disk 1901 can be adjusted along the axis of the omni-sonic energy source tip 101 by a threading mechanism 1902 located on the omni-sonic energy source tip 101.
  • the stop disk 1901 is threaded onto the omni-sonic energy source tip 101 by engaging the threading mechanism 1902 on the omni-sonic energy source tip 101 and elevated to a position on the omni-sonic energy source tip 101 which would place, when the containment chamber 701 is then connected to the omni-sonic energy source tip 101 and the connecting end 703 of the containment chamber abuts the stop disk 1901 , the working end 108 of the omni-sonic energy source tip 101 in or near the plane of the contact end 703 of the containment chamber 701 .
  • the omni-sonic energy source tip 101 or 201 can touch, or be close to the contact surface 301 being treated.
  • the end working 108 or 208 of the omni- sonic energy source tip 101 or 201 is approximately perpendicular to the contact surface 301 .
  • the distance between the contact surface 301 and the working end 108 or 208 of the omni-sonic energy source tip 101 or 201 it can be either adjusted within in the containment chamber 601 or 701 , as further described herein, or fixed within the containment chamber 601 or 701 in relation to the plane of the contact end 602 or 702 of the containment chamber 601 or 701 .
  • the location of the working end 108 or 208 of the omni-sonic energy source tip 101 or 201 in relation to the plane of the contact end 602 or 702 of the containment chamber 601 or 701 may depend on, for example, the viscosity of the active ingredient 401 . Based on the viscosity, surface tension, and other formulation criteria of the active ingredient 401 , the distance of the working end 108 or 208 of the omni-sonic energy source tip 101 or 201 from contact surface 301 can be adjusted to allow for the optimal efficacy or penetration.
  • the active ingredients 401 or 1201 can be stored in a storage container 1106 which, upon a desired titration, can be released into the containment chamber 601 or 701 , or on the contact surface 301 .
  • the storage container 1106 can be, as non-limiting examples, either a syringe or unit dose plastic type container.
  • the storage container 1 106 can be connected to the containment chamber 601 or 701 or the omni-sonic source 102 or 103 through a port 1 101 or 1 103, and/or with a rubber hose or tubing 1 107.
  • the active ingredient 401 or 1201 can then be released onto either the contact surface 301 , or through the omni-sonic source tip or into the containment chamber.
  • the storage container holding the agent can also be separate, and release its contents onto the contact surface 301 directly, not shown.
  • the storage container or a separate storage container, not shown, can also include aqueous solutions such as water, solvent and thickeners to apply to the contact surface 301 to remove residue 1 106.
  • aqueous solutions such as water, solvent and thickeners to apply to the contact surface 301 to remove residue 1 106.
  • the omni-sonic energy source tip 101 or 201 , the containment chamber 601 or 701 or the active ingredient can be heated to further enhance the effects of the omni-sonic waves imparted to the active ingredient.
  • the containment chamber 601 or 701 , in conjunction with the omni- sonic energy source tip 101 or 201 and the active ingredient 401 or 1201 have the ability to change, enhance, and alter the normal chemical reaction, breakdown, release of free radicals in the active ingredient 401 or 1201 .
  • the containment chamber 601 or 701 focuses the energy from the omni-sonic energy source tip 101 or 201 into the molecules of the active ingredient 401 or 1201 , exciting them, reprocessing them, while changing their potency or strength depending on the level of energy applied, while the activate ingredient outside 401 or 1201 of the containment chamber 601 or 701 , residing elsewhere within the oral cavity, remains at the un-excited potency or strength.
  • Omni-sonic energy enhances cleaning, whitening or medicating by breaking up organic molecules of the active ingredient 401 or 1201 into smaller pieces, increasing surface area to be enhanced, an allowing more active ingredient 401 or 1201 to contact the contact surface 301 .
  • Omni-sonic energy also enhances cleaning by accelerating active ingredient molecules, increasing the action against the surface molecules, for example tooth stain molecules.
  • the omni-sonic source tip 101 or 201 , the containment chamber 601 or 701 , and active ingredient 401 or 1201 a unique system is created that allows a practitioner to direct, control, and contain, active ingredient 401 or 1201 for deep penetration, increased action, and increased cleaning, whitening or therapeutic outcomes.
  • an active ingredient 401 or 1201 with an omni-sonic energy source 102 or 103 stains can be removed without the use of excessive force, rubbing, pressure or other manipulation which causes wear and tear on contact surfaces 301 , for example tooth surfaces.
  • the present invention also comprises, as shown in Figure 20, a method of enhancing an contact surface comprising applying an active ingredient 2001 , containing and directing the active ingredient to an area of the contact surface 2002; using an omni-sonic energy source tip to impart creating omni-sonic waves in the active ingredient, having an omni-sonic frequency and an amplitude 2003, and, optionally rinsing the contact surface with an aqueous solution 2004.
  • a type of contact surface is a human tooth, human gums, human cheek skin or human bone.
  • the method further comprises varying the omni- sonic frequency, the amplitude or both 2101 .
  • Another embodiment of the method further comprises providing an omni-sonic energy source to the omni-sonic energy source tip to create the omni-sonic waves 2102.
  • the omni-sonic energy source is selected for having properties compatible with omni-sonic wave creation and with chemistry of the active ingredient 2103.
  • the method further comprises providing power to the omni-sonic energy source 2105.
  • the power may be electrical power, pneumatic power or mechanical power 2107.
  • the method further comprises providing a power source to provide electrical power to the omni- sonic source 2108.
  • the method further comprises selecting a power source selected from a group consisting of a battery and a plug-in type to an electrical outlet 2109.
  • a further embodiment of the method comprises varying the power provided to the omni-sonic energy source 2106.
  • the method further comprises impregnating a working end of the omni- sonic energy source tip with active ingredients 21 11 .
  • the working end of the omni- sonic energy source tip is selected from a group consisting of bristle fibers, a surface with perforations, a surface onto which a sticker or variable sleeve can be applied, or an uneven surface 21 12.
  • the method further comprises selecting a material softer than a human tooth and attaching said material to the working end of the omni-sonic energy source tip 21 13.
  • An embodiment of the method of the present invention further comprises selecting an omni-sonic energy source from a group consisting of a piezoelectric device or magnetostrictive device 2104.
  • the method further comprises imparting omni-sonic energy from the working end of the omni-sonic energy source tip directly to the contact surface.
  • the method further comprises selecting the active ingredient from one or more of a cleaning agent, a whitening agent or a therapeutic agent 2201.
  • the method further comprises dispensing the active ingredient using a device that controls the application amount, application location or both 2202.
  • the method further comprises applying an effective amount of the active ingredient based on the contact surface to be enhanced 2203.
  • the method further comprising selecting the active ingredient from a group consisting of amylase enzyme, bleach catalyst and mixtures thereof 2204.
  • the method further comprises rinsing the contact surfaces to be enhanced with an aqueous solution 2205.
  • the method further comprises increasing penetration of the active ingredient into the contact surface 2206.
  • the method wherein the active ingredient is a portion of a solution, which portion is from about 0.0001 % to about 100% by weight 2207.
  • the method of the present invention further comprises selecting the active ingredient, comprising a cleaning agent, from a group consisting of builders, surfactants, enzymes, bleach activators, bleach boosters, bleaches, peroxides, alkalinity sources, antibacterial agent, anti-microbial agents, antioxidants, electrolytes, pH modifiers, thickeners, abrasives, enzyme stabilizers, solvents, humectants, and foamers 2302.
  • a cleaning agent from a group consisting of builders, surfactants, enzymes, bleach activators, bleach boosters, bleaches, peroxides, alkalinity sources, antibacterial agent, anti-microbial agents, antioxidants, electrolytes, pH modifiers, thickeners, abrasives, enzyme stabilizers, solvents, humectants, and foamers 2302.
  • the active ingredient may also comprise a therapeutic agent, selected from a group consisting of fluorides, antimicrobials, anti- tartar agents, varnishes, anti-sensitivity products, anticahes agents, halitosis agents, periodontal disease agents, antibiotics, antiviral agents, dry mouth agents, anesthetics, aphthous ulcer medicaments, and wart medicaments 2301.
  • the active ingredient may also comprise selecting the active ingredient comprising dental medicaments 2303. Heat may also be applied to the active ingredient 2304. [0109] As shown in Figure 24, the method of the present invention comprising increasing a rate of enhancing the contact surface.
  • An embodiment of the method of the present invention further comprising using a containment chamber to contain and direct at least a portion of the active ingredient to remain in contact with the contact surface.
  • the method of the present invention wherein the containment chamber comprises a contact end, an opening at the contact end, a connecting end opposing the contact end and walls connected to the connecting end and forming the opening at the contact end 2402.
  • the method further comprises selecting a size of the opening of the containment chamber based on whether the contact end of the containment chamber is submerged into the active ingredient or is contacting a surface of the active ingredient 2403.
  • the method of the present invention further comprises enclosing at least a portion of a omni-sonic energy source tip within the containment chamber 2401 .
  • the method of the present invention further comprises creating a tent, bubble, cup, or other sealed or non-sealed environment with the containment chamber 2404.
  • the method further comprises trapping, recycling and directing the active ingredient within the containment chamber 2405.
  • the method further comprises moving the omni-sonic waves and active ingredient across the hard surface, the soft surface or both 2406.
  • the method of the present invention further comprises containing and directing omni-sonic waves to the active ingredient 2407.
  • the method further comprises maintaining contact between the containment chamber and the hard surface, soft surface or both 2408.
  • the method of the present invention also comprises containing and directing at least a portion of the active ingredient to remain in contact with the contact surface 2409.
  • the present invention also comprises a process for removing stains from, removing a deposit from a contact surface comprising: (i) selecting stained portion contact surface 2501 , (ii) applying an effective amount of an active ingredient to a contact surface 2502, (iii) containing and directing the active ingredient and a working end of a omin-sonic energy source tip at or on stained portion of the contact surface 2503 within the confined space of a containment chamber 2503, (iv) activating the omni-sonic energy source tip to impart omni-sonic waves to the active ingredient and/or the contact surface 2504 so as to enhance the contact surface, and (v) optionally, rinsing said contact surface with an aqueous solution 2505.
  • the process for removing stains from a contact surface also including activators or chemicals that will interact with the active ingredient to increase stain removal 2601.
  • the process for removing stains from a contact surface also including activators or chemicals that will interact with the omni-sonic waves to increase stain removal 2602.
  • cleaning agents include amylase enzyme, bleach catalyst peroxides, solvents, and mixtures thereof 2603.
  • aqueous solutions include but are not limited to water, solvents and thickeners 2604.
  • Typical treatment times range from about 1 second to about 5 minutes depending on if the contact surface to be enhanced is having a therapeutic applied. Total treatment times can be broken into segments, allowing for the addition of different active ingredients and to allow the oral to rest and/or re-hydrate.
  • Non-limiting active ingredients include any FDA approved oral care ingredient, or combinations thereof, used in cleaning of teeth and bleaching of teeth or any other ingredient considered safe for use in the field of oral care, or combinations thereof, including enzyme systems, solvents, thickeners, surfactants, cleaners, flavors 2605.
  • Active ingredients can also include: anesthetics for hard or soft tissues, fluorides used as anti-caries agents, or tooth surface hardening chemistry, desensitizing agents, remineralization agents, or antimicrobial agents, aphthous ulcer medicaments, antiviral medicaments, halitosis agents, salivary flow agents, other remineralization agents such as Calcium phosphate, Recaldent, or ACP, NovaminTM, antibiotics and antimicrobial agents 2606.
  • anesthetics for hard or soft tissues fluorides used as anti-caries agents, or tooth surface hardening chemistry, desensitizing agents, remineralization agents, or antimicrobial agents, aphthous ulcer medicaments, antiviral medicaments, halitosis agents, salivary flow agents, other remineralization agents such as Calcium phosphate, Recaldent, or ACP, NovaminTM, antibiotics and antimicrobial agents 2606.
  • the invention includes a process for delivery of therapeutic agents comprising selecting a portion of a contact surface for delivery of therapeutic agents 2701 ; applying an effective amount of therapeutic agent to the selected portion of the contact surface 2702; containing and directing the active ingredient and omni-sonic waves to said portion of the contact surface 2703; activating a working end of an omni-sonic energy source tip to impart omni-sonic energy to the therapeutic agent 2704; and optionally, rinsing said contact surface with an aqueous solution 2705.
  • the process further comprising selecting the contact surface from a group consisting of teeth, gums, lips, bone, periodontal ligaments or teeth sulci.
  • An embodiment of present invention further comprises, as shown in
  • a containment chamber attachment 701 comprising an opening at a contact end 702; a connecting end opposing the contact end 703, said connecting end including a passage to permit a working end of an omni-sonic energy source tip 201 be placed into the containment chamber attachment 701 ; and walls defining the opening at the contact end 702 and connected to the connecting end 703.
  • the containment chamber attachment wherein the walls are cylindrically shaped as shown in Figure 7a.
  • a further embodiment of the containment chamber attachment wherein the walls are tapered with a portion of the side walls at the contact end being wider than a portion of the side walls at the connecting end as shown in Figure 15A.
  • the walls of the containment chamber consist of three walls as shown in Figure 7B.
  • the walls of the containment chamber attachment consist of four walls as shown in Figure 15C.
  • the containment chamber attachment of the present invention as shown in Figure 14A, further comprising two parts, a first part 1401 that includes a first portion of the connecting end 703, a first portion of the walls physically connected to the first portion of the connecting end 703 and a first portion of the contact end 702 comprising a first portion of an edge defining the opening, a second part 1402 that includes a second portion of the connecting end 703, a second portion of the walls physically connected to the second portion of the connecting end 703 and a second portion of the contact end 702 comprising a second portion of the edge defining the opening, and a joining mechanism to connect the first part 1401 and the second part 1402.
  • the containment chamber attachment wherein the joining mechanism is a snap mechanism or latch mechanism.
  • the containment chamber attachment as shown in Figure 8B, further comprising a molded slot in the opening of the contact end 702; and a seal 801 , as shown in Figure 8A, shaped to tightly fit the molded slot as shown in Figure 8C.
  • the containment chamber attachment wherein the seal provides an interface between the contact end and a contact surface as shown in Figure 9.
  • the connecting end of the containment chamber attachment is configured for attachment to an omni-sonic energy source tip, an omni-sonic energy source or a handle for the omni-sonic energy source as shown in Figures 15A, 15B, 16A and 18A.
  • the containment chamber attachment further comprising a working end of the omni-sonic energy source tip is located inside the containment chamber attachment, as shown in Figure 16B, and is located in a plane defined by the opening as shown in Figure 18B.
  • the containment chamber attachment further comprises a working end of the omni-sonic energy source tip is located inside the containment chamber attachment and is located at a distance from the plane defined by the opening of the containment chamber.
  • the containment chamber attachment further comprises at least one port, said at least one port configured for extraction of residue from inside the containment chamber attachment.
  • the containment chamber attachment further comprising a tube 1 106 attached to the at least one port, a device 1 105 located on the tube to restrict or halt the extraction of residue.
  • the containment chamber attachment wherein the device located on the tube to restrict or halt the extraction residue further comprising a finger spring pinch switch located on the tube.
  • the containment chamber attachment further comprising at least one port, said at least one port configured for delivery of an active ingredient into the containment chamber attachment.
  • the containment chamber attachment further comprising finger grip serrations 1502 on the walls near the connecting end, as shown in Figures 15A and 15B.
  • the containment chamber attachment further containing an O-ring 1501 , inserted at the connecting end and configured to accept and connect the handle to the connecting end.
  • the containment chamber attachment further comprising a gasket disk 1601 inserted into the connecting end, said gasket disk including at least one slit, to allow a working end of an omni-sonic energy source tip to be placed through the gasket disk and into the containment chamber attachment, as shown in Figures 16A, 16B, 18A and 18B.
  • the containment chamber attachment wherein the at least one slit is three slits radiating at equal distances from the center of the gasket disk.
  • a containment chamber attachment 601 comprising a top wall having a width and a length, two opposing side walls connected to at least a portion of the top side, a contact end 602, as shown in Figure 6C, connected to the top wall and the two side walls, an opening opposing the top wall, a connecting end 601 opposing the contact end, and said connecting end including a passage to permit a working end of an omni-sonic energy source tip to be placed into the containment chamber attachment 601 and an attachment, not shown, to connect the containment chamber attachment to an omni-sonic dental apparatus.
  • the containment chamber attachment 601 further comprises a first port 1 101 in the containment chamber attachment 601 either for delivery of an active ingredient or other solution into the containment chamber attachment 601 or for extraction of residue from the containment chamber attachment 601 .
  • the containment chamber attachment 601 as shown in Figure 1 1 B, further comprises a second port 1 102 in the containment chamber attachment, either for importing an active ingredient or other solution into the containment chamber attachment 601 or for extraction of residue from the containment chamber attachment 601 .
  • the present invention relates to a method of enhancing (e.g., whitening, cleaning, enhancing, etc.) a contact surface comprising: applying an active ingredient (e.g., cleaning agent, medicament, etc.) to at least one area; containing and directing the active ingredient to an area of the contact surface; covering the at least one area with a film; creating omni-sonic waves, in the active ingredient, having an omni-sonic frequency and an amplitude.
  • suitable films include, but are not limited to, polymer films (e.g., flexible polymer based sandwich wraps), flexible metal foils (e.g., aluminum foil), wax films, cotton paper films, cellulose-based films, etc.
  • this method is accomplished by a unitary piece that includes all of an active ingredient, a film and a guard for guarding against unwanted dispersal of the active ingredient when the method is being enacted via the application of omni-sonic waves.
  • the active ingredient can be any suitable active ingredient within the scope of the present invention.

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  • Health & Medical Sciences (AREA)
  • Dentistry (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Cosmetics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

La présente invention concerne des systèmes, des kits de produit, des procédés, des processus et des dispositifs utilisant des ondes omni-soniques pour le nettoyage, le blanchiment ou l'amélioration d'un agent de nettoyage, d'un agent de blanchiment, et de l'absorption, l'administration et l'efficacité d'un médicament sur des tissus durs et des parties molles. Dans un premier mode de réalisation, l'invention concerne un système d'amélioration de surfaces de contact comprenant une source d'énergie omni-sonique activée par une source d'alimentation et une pointe de source d'énergie omni-sonique possédant une certaine longueur et une certaine largeur.
PCT/US2010/034440 2009-05-11 2010-05-11 Système, procédé et produit de nettoyage, de blanchiment et d'amélioration de surface thérapeutique utilisant des ondes soniques ou ultrasoniques ou des flux acoustiques Ceased WO2010132496A1 (fr)

Applications Claiming Priority (2)

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US61/177,080 2009-05-11

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WO2013151585A1 (fr) * 2012-04-05 2013-10-10 American Eagle Instruments, Inc. Dispositif et procédé de diffusion en continue acoustique induite par photons
EP2658474A4 (fr) * 2010-12-30 2014-10-22 Dentovations Inc Procédé et dispositif pour le blanchiment des dents au moyen de la sonochimie
WO2017202943A1 (fr) * 2016-05-24 2017-11-30 Credentis Ag Procédé et produit pour le traitement des caries
WO2022098330A3 (fr) * 2020-11-06 2022-07-07 T.C. Ankara Universitesi Rektorlugu Dispositif de nettoyage de tartre au moyen d'ondes sonores

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