[go: up one dir, main page]

WO2010037878A9 - Utilisation de nanoparticules de métaux nobles en tant qu'immunomodulateurs et composition immunomodulatrice - Google Patents

Utilisation de nanoparticules de métaux nobles en tant qu'immunomodulateurs et composition immunomodulatrice Download PDF

Info

Publication number
WO2010037878A9
WO2010037878A9 PCT/ES2009/000476 ES2009000476W WO2010037878A9 WO 2010037878 A9 WO2010037878 A9 WO 2010037878A9 ES 2009000476 W ES2009000476 W ES 2009000476W WO 2010037878 A9 WO2010037878 A9 WO 2010037878A9
Authority
WO
WIPO (PCT)
Prior art keywords
nanoparticles
utilisation
immunomodulators
noble metals
immunomodulator composition
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/ES2009/000476
Other languages
English (en)
Spanish (es)
Other versions
WO2010037878A1 (fr
Inventor
David POZO PÉREZ
Rafael FERNÁNDEZ MONTESINOS
Juan Luis Herrera Cabello
José Antonio MEJÍAS ROMERO
Paula Margarita CASTILLO HERNÁNDEZ
Ana Paula ZADERENKO GARCÍA
Pedro Pablo GARCÍA LUNA
José Luis PEREIRA CUNILL
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Fundacion Publica Andaluza Para La Gestion de la Investigacion En Salud En Sevilla
Universidad de Sevilla
Universidad Pablo de Olavide
Original Assignee
Fundacion Publica Andaluza Para La Gestion de la Investigacion En Salud En Sevilla
Universidad de Sevilla
Universidad Pablo de Olavide
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fundacion Publica Andaluza Para La Gestion de la Investigacion En Salud En Sevilla, Universidad de Sevilla, Universidad Pablo de Olavide filed Critical Fundacion Publica Andaluza Para La Gestion de la Investigacion En Salud En Sevilla
Publication of WO2010037878A1 publication Critical patent/WO2010037878A1/fr
Publication of WO2010037878A9 publication Critical patent/WO2010037878A9/fr
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/69—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
    • A61K47/6921—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit the form being a particulate, a powder, an adsorbate, a bead or a sphere
    • A61K47/6925—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit the form being a particulate, a powder, an adsorbate, a bead or a sphere the form being a microcapsule, nanocapsule, microbubble or nanobubble
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51—Nanocapsules; Nanoparticles
    • A61K9/5107—Excipients; Inactive ingredients
    • A61K9/5115—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/24—Heavy metals; Compounds thereof
    • A61K33/38—Silver; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/51—Nanocapsules; Nanoparticles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Nanotechnology (AREA)
  • Optics & Photonics (AREA)
  • Physics & Mathematics (AREA)
  • Biomedical Technology (AREA)
  • Inorganic Chemistry (AREA)
  • Immunology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

La présente invention concerne l'utilisation des effets immunomodulateurs des nanoparticules métalliques d'argent fonctionnalisées avec de la tiopronine [N-(2-mercaptopropionyl) glycine]. Un second aspect de cette invention concerne une composition immunomodulatrice contenant des nanoparticules d'argent fonctionnalisées avec de la tiopronine.
PCT/ES2009/000476 2008-10-02 2009-09-25 Utilisation de nanoparticules de métaux nobles en tant qu'immunomodulateurs et composition immunomodulatrice Ceased WO2010037878A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
ESP200802831 2008-10-02
ES200802831A ES2335852B1 (es) 2008-10-02 2008-10-02 Utilizacion de nanoparticulas de metales nobles como inmunomoduladores y composicion inmunomoduladora.

Publications (2)

Publication Number Publication Date
WO2010037878A1 WO2010037878A1 (fr) 2010-04-08
WO2010037878A9 true WO2010037878A9 (fr) 2010-06-10

Family

ID=42026651

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/ES2009/000476 Ceased WO2010037878A1 (fr) 2008-10-02 2009-09-25 Utilisation de nanoparticules de métaux nobles en tant qu'immunomodulateurs et composition immunomodulatrice

Country Status (2)

Country Link
ES (1) ES2335852B1 (fr)
WO (1) WO2010037878A1 (fr)

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0772776B1 (fr) * 1994-07-27 2000-03-22 Herbert Dr. Pilgrimm Particules superparamagnetiques, leur procede de production et leur utilisation
US20070048383A1 (en) * 2005-08-25 2007-03-01 Helmus Michael N Self-assembled endovascular structures
US20090053139A1 (en) * 2006-07-12 2009-02-26 Regents Of The University Of Michigan Dendrimer based compositions and methods of using the same
ES2331781B1 (es) * 2008-01-31 2010-10-27 Universidad Pablo De Olavide Nanoparticulas metalicas funcionalizadas con el neuropeptido vip y procedimiento de preparacion.

Also Published As

Publication number Publication date
ES2335852A1 (es) 2010-04-05
WO2010037878A1 (fr) 2010-04-08
ES2335852B1 (es) 2011-02-28

Similar Documents

Publication Publication Date Title
ZA200901578B (en) Metal powder
EP2650501A4 (fr) Logement de turbine en tôle métallique
EP2383057A3 (fr) Composition contenant des particules métalliques plates et matériau de protection contre les rayons de chaleur
PL2178660T3 (pl) Cienka odlewana taśma stalowa ze zmniejszonym mikropękaniem
WO2009004593A3 (fr) Procédés de préparation d'épinéphrine
EP2267312A4 (fr) Membrane métallique
ZA200903076B (en) Metal Powder
EP2231891A4 (fr) Poudre d'acier faiblement alliée
WO2010037878A9 (fr) Utilisation de nanoparticules de métaux nobles en tant qu'immunomodulateurs et composition immunomodulatrice
WO2007080593A3 (fr) Activité relative à l'ubiquitination siva et/ou à la dégradation de siva et modulateurs associés
GB0819096D0 (en) Pressure metal gauze assembly
WO2008061925A3 (fr) Matériau de boîtier d'un composant de traitement de gaz d'échappement
TJ43Y3 (en) The protection an alloy on the basis of aluminium
AU2008900484A0 (en) Thin cast steel strip with reduced microcracking
AU2007900443A0 (en) Electrochemical Reduction of Metal Oxides
AU2007902250A0 (en) Eutectic metal alloy
GB0612917D0 (en) Metallic compositions,preparations and uses
AU2006901575A0 (en) Improved processing of metal values from concentrates
AU2005904121A0 (en) Electrochemical reduction of metal oxides
AU2006904727A0 (en) Metal-coated steel strip
AU2006904713A0 (en) Metal-coated steel strip
AU2006905221A0 (en) Metal oxide nanofibre filter
HK1128488A (en) Proline-specific proteases free from amylolytic activities
HK1117464A (en) Compositions comprising elemental metals and uses therefor
AU2005901676A0 (en) Silicone coated metal oxide particles

Legal Events

Date Code Title Description
121 Ep: the epo has been informed by wipo that ep was designated in this application

Ref document number: 09817310

Country of ref document: EP

Kind code of ref document: A1

NENP Non-entry into the national phase

Ref country code: DE

122 Ep: pct application non-entry in european phase

Ref document number: 09817310

Country of ref document: EP

Kind code of ref document: A1