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WO2010008244A3 - 약제학적 제제 - Google Patents

약제학적 제제 Download PDF

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Publication number
WO2010008244A3
WO2010008244A3 PCT/KR2009/003969 KR2009003969W WO2010008244A3 WO 2010008244 A3 WO2010008244 A3 WO 2010008244A3 KR 2009003969 W KR2009003969 W KR 2009003969W WO 2010008244 A3 WO2010008244 A3 WO 2010008244A3
Authority
WO
WIPO (PCT)
Prior art keywords
complications
active ingredient
pharmacologically active
blood pressure
pharmaceutical preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/KR2009/003969
Other languages
English (en)
French (fr)
Other versions
WO2010008244A2 (ko
Inventor
김성욱
전성수
구자성
김병하
이나영
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hanall Pharmaceutical Co Ltd
Original Assignee
Hanall Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hanall Pharmaceutical Co Ltd filed Critical Hanall Pharmaceutical Co Ltd
Publication of WO2010008244A2 publication Critical patent/WO2010008244A2/ko
Publication of WO2010008244A3 publication Critical patent/WO2010008244A3/ko
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0002—Galenical forms characterised by the drug release technique; Application systems commanded by energy
    • A61K9/0004—Osmotic delivery systems; Sustained release driven by osmosis, thermal energy or gas
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)

Abstract

본 발명은 약리학적 활성성분으로 안지오텐신-2 수용체 길항제를 포함하는 선방출성 구획, 및 약리학적 활성성분으로 베타 아드레날린 차단제를 포함하는 지연방출성 구획을 포함하는 약제학적 제제를 제공하며, 본 발명의 제제는 균등한 항압작용과 합병증 예방 작용을 나타내며, 특히 합병증 발생 위험시간대에 혈압을 균등하게 유지시켜 줄 수 있어, 합병증을 지닌 고혈압 환자, 수면 중 혈압억제가 필요한 환자 등에 유용하고, 약물간 상호작요에 따른 부작용 감소에 효과적이라는 장점이 있다.
PCT/KR2009/003969 2008-07-18 2009-07-17 약제학적 제제 Ceased WO2010008244A2 (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR10-2008-0069793 2008-07-18
KR20080069793 2008-07-18

Publications (2)

Publication Number Publication Date
WO2010008244A2 WO2010008244A2 (ko) 2010-01-21
WO2010008244A3 true WO2010008244A3 (ko) 2010-05-14

Family

ID=41550875

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/KR2009/003969 Ceased WO2010008244A2 (ko) 2008-07-18 2009-07-17 약제학적 제제

Country Status (1)

Country Link
WO (1) WO2010008244A2 (ko)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105030718B (zh) * 2015-08-18 2018-01-30 石家庄格瑞药业有限公司 一种盐酸阿罗洛尔制剂及其制备方法
CN105012246B (zh) * 2015-08-19 2018-04-06 湖北博华农牧科技有限公司 一种纳米氧化锌包膜工艺
KR101750689B1 (ko) * 2015-09-15 2017-06-26 주식회사 종근당 약제학적 복합제제
US20220175812A1 (en) 2020-12-03 2022-06-09 Battelle Memorial Institute Polymer nanoparticle and dna nanostructure compositions and methods for non-viral delivery
JP2024516108A (ja) 2021-04-07 2024-04-12 バテル・メモリアル・インスティテュート 非ウイルス性担体を同定および使用するための迅速な設計、構築、試験、および学習技術
WO2025072751A1 (en) 2023-09-29 2025-04-03 Battelle Memorial Institute Polymer nanoparticle compositions for in vivo expression of polypeptides
US12441996B2 (en) 2023-12-08 2025-10-14 Battelle Memorial Institute Use of DNA origami nanostructures for molecular information based data storage systems

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20050000556A (ko) * 2002-05-17 2005-01-05 노파르티스 아게 심근 경색증의 속발 예방을 위한 안지오텐신 ｉｉ 수용체차단제 및 베타-차단제의 조합물
KR100582347B1 (ko) * 2004-12-30 2006-05-22 한미약품 주식회사 3-하이드록시-3-메틸글루타릴 조효소 ａ 환원효소 억제제및 고혈압 치료제의 복합제제 및 그의 제조방법
KR20070078625A (ko) * 2006-01-27 2007-08-01 씨제이 주식회사 멀티플 유닛 타입 서방성 경구 제제 및 그 제조방법
KR20080032616A (ko) * 2006-10-10 2008-04-15 한올제약주식회사 시간차 투약 원리를 이용한 심혈관계 질환 치료용 복합제제

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20050000556A (ko) * 2002-05-17 2005-01-05 노파르티스 아게 심근 경색증의 속발 예방을 위한 안지오텐신 ｉｉ 수용체차단제 및 베타-차단제의 조합물
KR100582347B1 (ko) * 2004-12-30 2006-05-22 한미약품 주식회사 3-하이드록시-3-메틸글루타릴 조효소 ａ 환원효소 억제제및 고혈압 치료제의 복합제제 및 그의 제조방법
KR20070078625A (ko) * 2006-01-27 2007-08-01 씨제이 주식회사 멀티플 유닛 타입 서방성 경구 제제 및 그 제조방법
KR20080032616A (ko) * 2006-10-10 2008-04-15 한올제약주식회사 시간차 투약 원리를 이용한 심혈관계 질환 치료용 복합제제

Also Published As

Publication number Publication date
WO2010008244A2 (ko) 2010-01-21

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