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WO2010096754A8 - Compositions and methods to prevent and/or treat cancer with pa -card - Google Patents

Compositions and methods to prevent and/or treat cancer with pa -card Download PDF

Info

Publication number
WO2010096754A8
WO2010096754A8 PCT/US2010/024904 US2010024904W WO2010096754A8 WO 2010096754 A8 WO2010096754 A8 WO 2010096754A8 US 2010024904 W US2010024904 W US 2010024904W WO 2010096754 A8 WO2010096754 A8 WO 2010096754A8
Authority
WO
WIPO (PCT)
Prior art keywords
card
methods
compositions
prevent
treat cancer
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/US2010/024904
Other languages
French (fr)
Other versions
WO2010096754A1 (en
Inventor
Tapas Das Gupta
Ananda Chakrabarty
Arsenio Fialho
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
CDG THEREAPEUTICS Inc
Original Assignee
CDG THEREAPEUTICS Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by CDG THEREAPEUTICS Inc filed Critical CDG THEREAPEUTICS Inc
Priority to CA2753121A priority Critical patent/CA2753121A1/en
Priority to AU2010215858A priority patent/AU2010215858A1/en
Priority to EP10744428A priority patent/EP2398486A4/en
Priority to SG2011059458A priority patent/SG174136A1/en
Priority to CN2010800160848A priority patent/CN102387809A/en
Priority to JP2011551270A priority patent/JP2012518417A/en
Publication of WO2010096754A1 publication Critical patent/WO2010096754A1/en
Publication of WO2010096754A8 publication Critical patent/WO2010096754A8/en
Priority to IL214757A priority patent/IL214757A0/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
    • A61K38/4873—Cysteine endopeptidases (3.4.22), e.g. stem bromelain, papain, ficin, cathepsin H
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/21—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Pseudomonadaceae (F)

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Zoology (AREA)
  • Oncology (AREA)
  • Hematology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

The present invention relates to methods and materials for killing cancer cells with proteins derived from bacteria. The invention specifically relates to Azurin, Laz, Pa-CARD, and fusion proteins Azu-H.8 and H.8-Azu, and their use in killing leukemia cells and/or ovarian cancer cells.
PCT/US2010/024904 2009-02-20 2010-02-22 Compositions and methods to prevent and/or treat cancer with pa -card Ceased WO2010096754A1 (en)

Priority Applications (7)

Application Number Priority Date Filing Date Title
CA2753121A CA2753121A1 (en) 2009-02-20 2010-02-22 Compositions and methods to prevent and/or treat cancer with pa-card
AU2010215858A AU2010215858A1 (en) 2009-02-20 2010-02-22 Compositions and methods to prevent and/or treat cancer with Pa -CARD
EP10744428A EP2398486A4 (en) 2009-02-20 2010-02-22 Compositions and methods to prevent and/or treat cancer with pa -card
SG2011059458A SG174136A1 (en) 2009-02-20 2010-02-22 Compositions and methods to prevent and/or treat cancer with pa -card
CN2010800160848A CN102387809A (en) 2009-02-20 2010-02-22 Compositions and methods to prevent and/or treat cancer with PA -CARD
JP2011551270A JP2012518417A (en) 2009-02-20 2010-02-22 Compositions and methods for preventing and / or treating cancer using PA-CARD
IL214757A IL214757A0 (en) 2009-02-20 2011-08-18 Compositions and methods to prevent and/or treat cancer with pa-card

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US15423609P 2009-02-20 2009-02-20
US61/154,236 2009-02-20
US17943509P 2009-05-19 2009-05-19
US61/179,435 2009-05-19

Publications (2)

Publication Number Publication Date
WO2010096754A1 WO2010096754A1 (en) 2010-08-26
WO2010096754A8 true WO2010096754A8 (en) 2011-04-28

Family

ID=42634238

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2010/024904 Ceased WO2010096754A1 (en) 2009-02-20 2010-02-22 Compositions and methods to prevent and/or treat cancer with pa -card

Country Status (9)

Country Link
EP (1) EP2398486A4 (en)
JP (1) JP2012518417A (en)
KR (1) KR20120000062A (en)
CN (1) CN102387809A (en)
AU (1) AU2010215858A1 (en)
CA (1) CA2753121A1 (en)
IL (1) IL214757A0 (en)
SG (1) SG174136A1 (en)
WO (1) WO2010096754A1 (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2007056362A2 (en) 2005-11-07 2007-05-18 Indiana University Research And Technology Corporation Glucagon analogs exhibiting physiological solubility and stability
WO2014049604A2 (en) * 2012-09-05 2014-04-03 Amrita Therapeutics Limited A novel biomedical device for cancer therapy
MX355078B (en) * 2013-02-05 2018-04-03 Agricultural Tech Res Inst Anti-mycoplasma spp. subunit vaccine.
CN103554187B (en) * 2013-09-18 2016-03-30 中国科学技术大学 Platinum complexes, protein complex of being obtained by this platinum compound and preparation method thereof
USD844857S1 (en) * 2017-10-05 2019-04-02 Western Interlock, Inc. Retaining wall corner block

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1144605B1 (en) * 1999-01-26 2009-12-16 University College London Dimethylarginine dimethylaminohydrolases
US20020164703A1 (en) * 2000-12-21 2002-11-07 Krzysztof Pawlowski Card-domain containing polypeptides, encoding nucleic acids, and methods of use
GB0211295D0 (en) * 2002-05-16 2002-06-26 Univ London Treatment of pain
CN101437842A (en) * 2004-10-07 2009-05-20 阿南达·查克拉博蒂 Cupredoxin derived transport formulations and methods of use thereof

Also Published As

Publication number Publication date
CN102387809A (en) 2012-03-21
SG174136A1 (en) 2011-10-28
IL214757A0 (en) 2011-11-30
EP2398486A4 (en) 2012-11-21
KR20120000062A (en) 2012-01-03
JP2012518417A (en) 2012-08-16
AU2010215858A1 (en) 2011-09-22
EP2398486A1 (en) 2011-12-28
CA2753121A1 (en) 2010-08-26
WO2010096754A1 (en) 2010-08-26

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