[go: up one dir, main page]

WO2010089421A3 - Menthyl carbamate compounds as active anti-cellulite ingredients - Google Patents

Menthyl carbamate compounds as active anti-cellulite ingredients Download PDF

Info

Publication number
WO2010089421A3
WO2010089421A3 PCT/EP2010/057117 EP2010057117W WO2010089421A3 WO 2010089421 A3 WO2010089421 A3 WO 2010089421A3 EP 2010057117 W EP2010057117 W EP 2010057117W WO 2010089421 A3 WO2010089421 A3 WO 2010089421A3
Authority
WO
WIPO (PCT)
Prior art keywords
cellulite
formula
cosmetic
compounds
carbamate compounds
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/EP2010/057117
Other languages
French (fr)
Other versions
WO2010089421A2 (en
Inventor
Imke Meyer
Heiko Oertling
Nadine Hillebrand
Claudia Gömann
Rahim Brodhage
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Symrise AG
Original Assignee
Symrise AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Symrise AG filed Critical Symrise AG
Priority to PCT/EP2010/057117 priority Critical patent/WO2010089421A2/en
Publication of WO2010089421A2 publication Critical patent/WO2010089421A2/en
Publication of WO2010089421A3 publication Critical patent/WO2010089421A3/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
    • A61K8/42—Amides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A61K8/4973—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with oxygen as the only hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A61Q19/06—Preparations for care of the skin for countering cellulitis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C271/00—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
    • C07C271/06—Esters of carbamic acids
    • C07C271/32—Esters of carbamic acids having oxygen atoms of carbamate groups bound to carbon atoms of rings other than six-membered aromatic rings
    • C07C271/34—Esters of carbamic acids having oxygen atoms of carbamate groups bound to carbon atoms of rings other than six-membered aromatic rings with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C271/00—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
    • C07C271/06—Esters of carbamic acids
    • C07C271/32—Esters of carbamic acids having oxygen atoms of carbamate groups bound to carbon atoms of rings other than six-membered aromatic rings
    • C07C271/36—Esters of carbamic acids having oxygen atoms of carbamate groups bound to carbon atoms of rings other than six-membered aromatic rings with the nitrogen atom of at least one of the carbamate groups bound to a carbon atom of a ring other than a six-membered aromatic ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C271/00—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
    • C07C271/06—Esters of carbamic acids
    • C07C271/32—Esters of carbamic acids having oxygen atoms of carbamate groups bound to carbon atoms of rings other than six-membered aromatic rings
    • C07C271/38—Esters of carbamic acids having oxygen atoms of carbamate groups bound to carbon atoms of rings other than six-membered aromatic rings with the nitrogen atom of at least one of the carbamate groups bound to a carbon atom of a six-membered aromatic ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/04—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D307/10—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D307/14—Radicals substituted by nitrogen atoms not forming part of a nitro radical
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/44—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D317/46—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D317/48—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring
    • C07D317/50—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to atoms of the carbocyclic ring
    • C07D317/58—Radicals substituted by nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/14—The ring being saturated

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Birds (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • Cosmetics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

The present invention relates to the cosmetic, dermatological or therapeutic use of certain menthyl carbamate compounds of formula (I) given below, preferably as anti-cellulite actives. The invention further relates to compositions and cosmetic, dermatological or therapeutic products comprising such compounds of formula (I), which are preferably suitable for the prophylaxis (prevention) and cosmetic treatment (combating) of cellulite in human beings, corresponding methods and to certain novel compounds of formula (I) wherein R1 denotes hydrogen or an organic radical having 1 to 14 carbon atoms, R2 denotes an organic radical having 1 to 14 carbon atoms, and wherein optionally R1 and R2 are covalently bonded to one another, preferably so that a 3 to 8 membered ring is formed.
PCT/EP2010/057117 2010-05-25 2010-05-25 Menthyl carbamate compounds as active anti-cellulite ingredients Ceased WO2010089421A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
PCT/EP2010/057117 WO2010089421A2 (en) 2010-05-25 2010-05-25 Menthyl carbamate compounds as active anti-cellulite ingredients

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/EP2010/057117 WO2010089421A2 (en) 2010-05-25 2010-05-25 Menthyl carbamate compounds as active anti-cellulite ingredients

Publications (2)

Publication Number Publication Date
WO2010089421A2 WO2010089421A2 (en) 2010-08-12
WO2010089421A3 true WO2010089421A3 (en) 2011-04-14

Family

ID=42542447

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2010/057117 Ceased WO2010089421A2 (en) 2010-05-25 2010-05-25 Menthyl carbamate compounds as active anti-cellulite ingredients

Country Status (1)

Country Link
WO (1) WO2010089421A2 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11731991B2 (en) * 2008-11-03 2023-08-22 Lehigh University Augmenting moieties for anti-inflammatory compounds
ES2397889B1 (en) 2011-03-25 2014-02-07 Lipotec, S.A. MODULATING PEPTIDES OF PGC-1 Alpha.
DE102013222164A1 (en) * 2013-10-31 2015-04-30 Deb Ip Limited Stabilized multiple emulsions as a skin protection product

Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4226043A1 (en) * 1992-08-06 1994-02-10 Haarmann & Reimer Gmbh Agents with a physiological cooling effect and active compounds suitable for these agents
WO1997021678A1 (en) * 1995-12-11 1997-06-19 Bayer Aktiengesellschaft Carbamic acid derivatives as leukotriene antagonists
WO2002002071A2 (en) * 2000-06-30 2002-01-10 Unilever Plc Cosmetic compositions containing substituted amide derivatives
US20030050318A1 (en) * 2001-09-07 2003-03-13 Kenneth Shirley Stable water in oil aminophylline emulsions
US20030134885A1 (en) * 2001-12-21 2003-07-17 Jean-Michel Bernardon Biaromatic ligand activators of PPARgamma receptors
WO2009144179A1 (en) * 2008-05-30 2009-12-03 Symrise Gmbh & Co. Kg L-menthyl-n-(2-hydroxyphenyl)carbamate
US20090311401A1 (en) * 2008-06-13 2009-12-17 Symrise Gmbh & Co. Kg Neo-Menthyl Derivatives as Flavor Materials

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4226043A1 (en) * 1992-08-06 1994-02-10 Haarmann & Reimer Gmbh Agents with a physiological cooling effect and active compounds suitable for these agents
WO1997021678A1 (en) * 1995-12-11 1997-06-19 Bayer Aktiengesellschaft Carbamic acid derivatives as leukotriene antagonists
WO2002002071A2 (en) * 2000-06-30 2002-01-10 Unilever Plc Cosmetic compositions containing substituted amide derivatives
US20030050318A1 (en) * 2001-09-07 2003-03-13 Kenneth Shirley Stable water in oil aminophylline emulsions
US20030134885A1 (en) * 2001-12-21 2003-07-17 Jean-Michel Bernardon Biaromatic ligand activators of PPARgamma receptors
WO2009144179A1 (en) * 2008-05-30 2009-12-03 Symrise Gmbh & Co. Kg L-menthyl-n-(2-hydroxyphenyl)carbamate
US20090311401A1 (en) * 2008-06-13 2009-12-17 Symrise Gmbh & Co. Kg Neo-Menthyl Derivatives as Flavor Materials

Also Published As

Publication number Publication date
WO2010089421A2 (en) 2010-08-12

Similar Documents

Publication Publication Date Title
WO2010097479A3 (en) Cyclohexyl carbamate compounds as active anti-cellulite ingredients
WO2010122178A3 (en) Cyclohexyl carbamate compounds as skin and/or hair lightening actives
WO2010097480A3 (en) Menthyl carbamate compounds as skin and/or hair lightening actives
WO2012016186A8 (en) Macrocyclic kinase inhibitors and uses thereof
MX2010003258A (en) Use of a novel natural agent in cosmetic compositions.
AU2011338389A8 (en) Bicyclic compounds as Pim inhibitors
WO2012085523A3 (en) Skin sanitizer compositions comprising alcohol based emulsion
TNSN08381A1 (en) Cosmetic active ingredient composed of arginine ferrulate and a microalgae and extract its uses
WO2013061004A8 (en) Novel disubstituted 3,4-diamino-3-cyclobutene-1,2-dione compounds for use in the treatment of chemokine-mediated diseases
WO2014141210A3 (en) Multifunctional immature dental pulp stem cells and therapeutic applications
PH12015502365B1 (en) Bace1 inhibitors
WO2012130820A3 (en) Isopentyl esters for the use in cosmetic, dermatological, or pharmaceutical compositions
WO2012076109A3 (en) 2-pyrones
PH12014502623A1 (en) Difluoro-hexahydro-cyclopentaoxazinyls and difluoro-hexahydro-benzooxazinyls as bace1 inhibitors
PH12014502541A1 (en) 5-amino [1,4] thiazines as bace 1 inhibitors
WO2012026813A3 (en) Analogs of geranylgeranylacetone and uses thereof
MX345695B (en) Heterocyclocarbonylaminothiazoles, cosmetic or dermatological preparations containing said heterocyclocarbonylaminothiazoles, and use thereof to combat or prevent undesired pigmentation of the skin.
WO2012161497A3 (en) Peptide derivatives having a superior moisturizing effect and uses thereof
WO2012112232A8 (en) METHODS AND COMPOSITIONS FOR TREATING β-THALASSEMIA AND SICKLE CELL DISEASE
MY160377A (en) Topical pharmaceutical compositions
WO2010089421A3 (en) Menthyl carbamate compounds as active anti-cellulite ingredients
MX353580B (en) Monounsaturated fatty acid for preventing and/or treating skin complexion imperfections.
MX2009012712A (en) Novel 4-phenyl-imidazole-2-thiones used as tyrosinase inhibitors, method for preparing same and use thereof in human medicine and cosmetology.
WO2012143857A8 (en) Combination of carotenoid, phytooestrogen and vitamin c for moisturizing the skin
MX2009012714A (en) Novel 4-heteroaryl-imidazole-2-thiones used as tyrosinase inhibitors, method for preparing same and use thereof in human medicine and cosmetology.

Legal Events

Date Code Title Description
121 Ep: the epo has been informed by wipo that ep was designated in this application

Ref document number: 10720016

Country of ref document: EP

Kind code of ref document: A2

NENP Non-entry into the national phase

Ref country code: DE

122 Ep: pct application non-entry in european phase

Ref document number: 10720016

Country of ref document: EP

Kind code of ref document: A2