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WO2010088219A3 - Reusable biosensor platform - Google Patents

Reusable biosensor platform Download PDF

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Publication number
WO2010088219A3
WO2010088219A3 PCT/US2010/022132 US2010022132W WO2010088219A3 WO 2010088219 A3 WO2010088219 A3 WO 2010088219A3 US 2010022132 W US2010022132 W US 2010022132W WO 2010088219 A3 WO2010088219 A3 WO 2010088219A3
Authority
WO
WIPO (PCT)
Prior art keywords
layer
disposed above
substrate layer
electrode layer
electrode
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/US2010/022132
Other languages
French (fr)
Other versions
WO2010088219A2 (en
Inventor
Junseok Chae
Seokheun Choi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of Arizona
Arizona State University ASU
Original Assignee
University of Arizona
Arizona State University ASU
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University of Arizona, Arizona State University ASU filed Critical University of Arizona
Publication of WO2010088219A2 publication Critical patent/WO2010088219A2/en
Publication of WO2010088219A3 publication Critical patent/WO2010088219A3/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/416—Systems
    • G01N27/447—Systems using electrophoresis
    • G01N27/44756—Apparatus specially adapted therefor
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/55—Specular reflectivity
    • G01N21/552—Attenuated total reflection
    • G01N21/553—Attenuated total reflection and using surface plasmons
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502715—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by interfacing components, e.g. fluidic, electrical, optical or mechanical interfaces

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Molecular Biology (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Electrochemistry (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)

Abstract

Techniques, apparatus and systems are described for generating reusable and reconfigurable biosensors. A microfluidic device includes a substrate layer and an electrode layer disposed above the substrate layer. A spacer layer is disposed above the electrode layers to form at least two channels. Another electrode layer is disposed above the spacer layer. Also, another substrate layer is disposed above the other electrode layer. The other substrate layer can include at least two inlets, each connected to one of the at least two channels, two outlets corresponding to the two inlets, and two electrical contacts filled with a conductive material to form a conductive feedthrough to the other electrode layer.
PCT/US2010/022132 2009-01-27 2010-01-26 Reusable biosensor platform Ceased WO2010088219A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US14772809P 2009-01-27 2009-01-27
US61/147,728 2009-01-27

Publications (2)

Publication Number Publication Date
WO2010088219A2 WO2010088219A2 (en) 2010-08-05
WO2010088219A3 true WO2010088219A3 (en) 2010-11-18

Family

ID=42396305

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2010/022132 Ceased WO2010088219A2 (en) 2009-01-27 2010-01-26 Reusable biosensor platform

Country Status (1)

Country Link
WO (1) WO2010088219A2 (en)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102010064392A1 (en) * 2010-10-29 2012-05-03 Endress + Hauser Conducta Gesellschaft für Mess- und Regeltechnik mbH + Co. KG Method for determining an analyte content of a liquid sample by means of a bioanalyzer
CN102243242A (en) * 2011-04-15 2011-11-16 中国人民解放军第二军医大学 Method for fixing protein on surface of polydimethylsiloxane
CN103512862B (en) * 2012-06-15 2018-01-05 黄辉 Optical microfluidic chip and test method based on signal differential detection
JP5907296B2 (en) * 2015-04-07 2016-04-26 コニカミノルタ株式会社 Measuring device and method for measuring
DE102016101001B4 (en) * 2016-01-21 2019-07-11 Leibniz - Institut Für Analytische Wissenschaften - Isas - E.V. Device for the detection and characterization of organic molecules in a liquid sample volume
DE102016123700B4 (en) * 2016-12-07 2025-06-05 Endress+Hauser Conducta Gmbh+Co. Kg Sensor for determining a measured value dependent on a concentration of reactive oxygen species
US11266840B2 (en) 2018-06-27 2022-03-08 Arizona Board Of Regents On Behalf Of Arizona State University Wireless cardiac pace making
US11696713B2 (en) 2019-03-15 2023-07-11 Arizona Board Of Regents On Behalf Of Arizona State University Contour electrocorticography (ECoG) array
US11428588B2 (en) 2019-03-28 2022-08-30 Arizona Board Of Regents On Behalf Of Arizona State University Fully-passive pressure sensors and methods for their use
AU2023377817A1 (en) * 2022-11-11 2025-04-24 Archer Materials Limited A device, system, and method for sensing an electronic property of fluid sample

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6136171A (en) * 1998-09-18 2000-10-24 The University Of Utah Research Foundation Micromachined electrical field-flow fractionation system
US20070065954A1 (en) * 2005-09-15 2007-03-22 Minoru Taya Surface plasmon resonance biosensor system for detection of antigens and method for determining the presence of antigens
US20080082715A1 (en) * 2006-09-29 2008-04-03 Honeywell International Inc. Data transfers over multiple data buses

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6136171A (en) * 1998-09-18 2000-10-24 The University Of Utah Research Foundation Micromachined electrical field-flow fractionation system
US20070065954A1 (en) * 2005-09-15 2007-03-22 Minoru Taya Surface plasmon resonance biosensor system for detection of antigens and method for determining the presence of antigens
US20080082715A1 (en) * 2006-09-29 2008-04-03 Honeywell International Inc. Data transfers over multiple data buses

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
ALLEN D. TAYLOR ET AL.: "Quantitative and simultaneous detection of four foodborne bacterial pathogens with a multi-channel SPR sensor", BIOSENSORS AND BIOELECTRONICS, vol. 22, 25 April 2006 (2006-04-25), pages 752 - 758 *
SEOKHEUN CHOI ET AL.: "A regenerative biosensing surface in microfluidics using electrochemical desorption of short-chain self-assembled monolayer", MICROFLUID NANOFLUID, vol. 7, 10 April 2009 (2009-04-10), pages 819 - 827 *
SEOKHEUN CHOI ET AL.: "Surface plasmon resonance protein sensor using Vroman effect", BIOSENSORS AND BIOELECTRONICS, vol. 24, 31 July 2008 (2008-07-31), pages 893 - 899 *
WOLFGANG KNOLL ET AL.: "Streptavidin arrays as supramolecular architectures in surface-plasmon optical sensor formats", COLLOIDS AND SURFACES A: PHYSICOCHEMICAL AND ENGINEERING ASPECTS, vol. 161, 31 December 2000 (2000-12-31), pages 115 - 137 *

Also Published As

Publication number Publication date
WO2010088219A2 (en) 2010-08-05

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