WO2010085903A1 - Administering device comprising a holding element for a fluid receptacle - Google Patents

Abstract

A device for administering a fluid product is disclosed, comprising a housing (1) and a receptacle seat (2) with a receptacle (2). A component (14) is arranged in the housing (1), said component (14) and the receptacle seat (2) being axially movable towards each other. According to the invention, a holding element (15) is releasably disposed on the component in a first position of the receptacle seat (2) relative to the component (14). In a second position, in which the receptacle seat (2) is moved in the direction of the component, the holding element (15) is released from the component (14) and is fastened to the receptacle seat (2) in such a way as to form a holding stop for the receptacle (3) in the receptacle seat (2).

Description

 ADMINISTRATION DEVICE WITH HOLDING ELEMENT FOR

FLUID RESERVOIR

TECHNICAL AREA

The present invention relates to an administration device for administering a fluid product, in particular an injection device in which a container is fastened by means of a container receptacle on a housing, according to the preamble of patent claim 1.

STATE OF THE ART

Administration devices for administering a fluid product are widely known in the medical, pharmaceutical or cosmetic arts. For example, preparations such as insulin or growth hormones are injected with such delivery devices. In general, the administration devices, or also called injection pens, a housing in which an administration mechanism is housed. To the housing, a fluid container can be connected directly or by means of a container receptacle and the delivery mechanism. Preferably, cartridges are used as containers, which have at one end a closed with a septum opening and are closed at the opposite end with a movably mounted plug. Cartridges are also known, which have two chambers separated by a second plug, in each of which a component of a fluid product is located, wherein the components can be mixed before use in the carpule. To deliver the product from the carpule, an injection needle is placed on the carpule or container receptacle such that it pierces the septum and forms a fluid connection to the interior of the container. The administration mechanism has, for example, a feed member which is displaced relative to the housing and while acting on the stopper of the carpule. By feeding the plug, the product in the container is released by the injection needle.

For example, EP 0 829 268 discloses a drug delivery device comprising a housing with an administering mechanism having a metering device for adjusting a dose of product to be administered and a piston rod which can be axially displaced relative to the housing. To the housing with the mechanical unit, a carpule holder can be connected by means of a threaded connection. The carpule holder may contain a product container in the form of a carpule with a slidable stopper and an opening closed by a septum. In this case, a trained at the front end shoulder of the carpule comes to rest against a counter-stop of the carpule holder and at the rear end of the feed member engages the stopper of the carpule. The product container is thus secured against axial movement within the carpule holder by the front stop on the container edge and the rear stop on the feed member. It is now possible to place a needle unit on the carpule holder in such a way that the septum of the cartridge is punctured. By feeding the plug inside the cartridge by means of the piston rod, the product can now be injected from the administering device.

In such delivery devices, the advancing member acts on the plug in the container immediately after insertion or already during insertion of the container receptacle. In this case, a pressure is already exerted on the product in the container. When placing or replacing an injection needle already released by this pressure a small amount of product through the injection needle. When piercing the Iηjektionsnadel can cause irritation or irritation of the skin by this contamination of the injection needle. In addition, this results in a loss of the product, which is then not available for administration to a patient.

It is therefore desirable that when placing a hypodermic needle unit on a product container or on a container receptacle with a product container no pressure is exerted on a plug within the container, but the container is still held securely in the container holder, so that when placing a hypodermic needle unit a fluid connection to the product in the container can be made reliably. This is particularly relevant in multi-chamber carbohydrate delivery devices in which the delivery product is made by only feeding the plugs within the container by mixing various components. Often, here, to advance the plugs within the container, a component of the delivery mechanism, such as a feed member, is used which is to be removed after mixing the components and prior to placement of a needle unit from the plug within the container.

It is therefore an object of the present invention to provide an administering device in which a container is held securely in a container receptacle which allows easy assembly of the individual components of the administering device, wherein the container contents are not affected by the support of the container within the device, and that is easy to handle.

PRESENTATION OF THE INVENTION

This object is achieved by the invention by an administering device according to claim 1. Advantageous embodiments and embodiments are described in the dependent claims.

A delivery device for administering a fluid product according to the present invention comprises a housing and a container receptacle in which a container is received with the fluid product. The housing is preferably cylindrical and receives an administration mechanism in itself. The delivery mechanism may include a metering device and a dispenser. The dispenser may include, among other things, a feed member slidably mounted in the housing for delivery of the fluid product from the container relative to the container.

In the housing, a component is mounted, which is preferably provided concentrically within the housing. The component can, for example, by a sleeve, a Sleeve segments or a component of the delivery mechanism, in particular be formed by the feed member. The component and the Behälteraufhahme are provided axially movable toward each other. In this case, either the component can be fixed relative to the housing and the Behälteraufhahme be moved in the direction of the component or the Behälteraufhahme is fixed relative to the housing and the component is moved to the Behälteraufhahme. In principle, it is also possible for both the component and the container receptacle to move relative to the housing, so that the component and the receptacle move toward one another.

According to the present invention, a holding element is provided, which is arranged in a first position of the Behälteraufhahme relative to the component detachably on the component and in a second position in which the Behälteraufhahme is displaced in the direction of the component, is released from the component and the Behälteraufhahme is fixed so that it forms a retaining stop for the container in the Behälteraufhahme. The component serves as a carrier component, which carries the holding element in the first position. However, the support member is releasably supported by the support member to be mounted in the second position to the Behälteraufhahme can. The support member or the retaining element has z. B. a predetermined breaking point. The holding member may be attached to the component, such as a feed member, at one end facing the container receptacle. However, it can also be arranged on a component which is remote from the container receptacle.

In an administering device according to the present invention, a holding member which can fix a container in a container receptacle is not provided directly on the container receptacle, but is attached to the container receptacle only upon insertion of the container receptacle into a housing of the administering device. As a result, the retaining element during insertion of the container into the container receptacle is not a hindrance, but the container can easily slide into the container receptacle. The fixation of the container within the Behälteraufhahme by a erfmdungsgemässes holding element does not attack a plug in the container and thus can not influence the product within the container. Rather, the retaining element engages the edge of the container and can thus hold it securely in the container receptacle. In the embodiments shown, it is particularly advantageous that the feed member can be used on the one hand as a support member for the holding element and on the other to advance the plug when mixing two components. It is advantageous that the holding element can be moved by means of the feed member in the direction of the container in the container receptacle, with an opposite movement of the feed member relative to the container receptacle, but is released from this and remains at the container receptacle as a retaining stop for the container. Thus, after advancement of the plugs in the containers, the advancing member can be withdrawn from the plug without loosening the holding element for holding the container in the container receptacle. When placing an injection needle unit on the receiving area of a container receptacle thus no pressure on the feed member is exerted on the fluid product inside the container, so that when placing the needle unit no product can escape.

The container receptacle is sleeve-like and can completely accommodate the container in itself. As a container, a conventional cartridge made of glass or plastic can be used, which has a taper at a front, which adjoins a shoulder of the container when it is inserted into the container receptacle. The taper forms a head portion of the container and has a container opening closed by a septum secured by a crimp over the opening. At the opposite end of the container this is closed by a movably mounted plug. Between the plug and the opening closed by the septum, the product to be administered is stored in the container. In particular, multi-chamber carpules may be used which have at least two chambers separated by another plug and which have a bypass for diverting a component from one chamber to the other chamber. If the container is inserted into the container receptacle, preferably the outer circumference of the container comes to lie on the inner circumference of the container receptacle, so that the container is held securely in the radial direction.

The container receptacle may have a blocking stop, which is an axial movement of the container relative to the container receptacle in a direction of insertion of the container in the Recording blocked. For this purpose, the Behälteraufhahme example, have an inwardly projecting shoulder on which abuts a shoulder of the cartridge, as soon as it is completely inserted into the Behälteraufhahme. At the shoulder of the container receptacle can connect a connection area, which receives the Karpulenkopf with the closed by the septum opening in it. The connection region of the container receptacle has a central opening and on its outer circumference may be provided a fastening structure to which an injection needle unit can be fastened. When an injection needle unit is placed on the connection area, an injection cannula held by the unit can project through the opening of the connection area and through the septum into the interior of the container and forms a fluid connection.

The container receptacle may be attached to the housing with the end opposite the terminal area. The container receptacle can, for example, be moved completely or only with a small area into the housing. Preferably, a guide device is provided between the housing and the Behälteraufhahme, which allows a defined positioning of the Behälteraufhahme in the housing. For example, the container housing can be inserted into the housing and e.g. lock in a certain position with the housing. Preferably, however, a thread is provided between the Behälteraufhahme and the housing, with which the container receptacle can be screwed into the housing. By screwing the Behälteraufhahme in the housing, at least part of the Behälteraufhahme is received within the housing.

The holding element may be annular and z. B. at one end of the component, such as the feed member, which faces the container receptacle. However, it can also be arranged on a component which is remote from the container receptacle.

If the container receptacle is moved axially in the direction of the component, such as the feed member, the holding element is released from the component by a stop in the container receptacle, for example the edge of the container, while this can be moved further relative to Behälteraufhahme. Preferably, the container receptacle is at least partially slipped over the component, so that the component and overlap the Behälteraufiiahme in the radial direction. Is the retaining element z. B. provided at a front end of a feed member, which faces the Behälteraufiiahme, the holding member can be introduced by means of the feed member in the Behälteraufiiahme and released from the feed member before the feed member strikes the plug in the container. Alternatively, however, the holding element can be arranged at a relatively remote to Behälteraufiiahme area of the feed member, ie at a distance from the front end of the feed member, the feed member. In this case, the feed member is moved in a movement of the feed member on the Behälteraufiiahme to first in the Behälteraufiiahme before the holding element is released from the feed member. In this case, the feed member z. B. acted on the plug in the container, such as for mixing of components or for a priming process, and only then the holding element is released from the feed member.

It is also possible to provide on the interior of the Behälterabiiahme a fastening means for the holding element, on which the holding element is held as soon as the holding element passes in the movement of the component, such as the feed member, and the Behälteraufiiahme relative to each other in the region of the fastening device. The fastening means may be provided at a location within the container receptacle which is provided at a defined distance from the edge of the container. The fastening means is preferably provided at a location within the container receptacle which adjoins the edge of a container so that the holding member comes to rest against the edge of the container when it is held by the fastening means. It is only necessary to ensure that the fastening device is not covered by the container. If the fastening device does not adjoin the edge of the container, so that the edge can assist in releasing the retaining element from the component, the fastening device holds the retaining element so firmly that the holding force between the retaining element and component is overcome and the retaining element alone by the holding on the fastening device is released from the component. In this case, the holding element can be placed in the Behälteraufiiahme with a predetermined distance from the edge of the container.

The fastening device, for example, by a fastener on Retaining element and a complementarily formed counter-fastening means may be provided on the Behälteraufhahme, wherein the fastening means and the counter-fastening means can engage in such a way that the holding element is secured in the axial direction in the Behälteraufhahme. The fastening means and the counter-fastening means can be provided, for example, by latching means or counter-latching means which can latch together. Preferably, the fastening means and the counter-fastening means are designed as external or internal threads. For example, a circumferential internal thread is provided on the inner circumference of the container receptacle, while an external thread is provided on the outer circumference of the holding element. The thread edges are formed so flexible that they initially in the axial direction over one another in an axial movement of the component, such as a feed member, and the Behälteraufhahme before the retaining element separates from the component, the internal thread comes to rest in the external thread. In order to ensure sufficient radial flexibility of the thread to each other, the external thread on the holding element can be divided into thread segments. There are at least two thread segments provided on opposite sides of the holding element, but it can also be provided three, four or five thread segments.

In an alternative embodiment, the retaining element z. B. may be provided as a metal ring, which has obliquely outwardly projecting locking prongs on the circumference. The retaining ring can be applied to the component, such. B. the feed member to be placed at the end, which faces the Behälteraufhahme or at a certain distance to this end. The retaining ring can be held in a groove on the component in a predetermined position. When inserting the Behälteraufhahme in the housing, the component is introduced into the interior of the Behälteraufhahme, wherein the latching teeth on the inner circumference of the Behälteraufhahme can slide along. The latching prongs are formed obliquely outward against the insertion direction projecting on the retaining ring. As soon as the component is moved counter to the insertion direction relative to the container receptacle, the latching prongs engage in the peripheral wall of the container receptacle. On the peripheral wall this ribs or grooves may additionally be provided. But the latching prongs can also hook directly into the inner peripheral wall, z. B. if this is made of plastic. The holding element is thus in the first position on the outer circumference of the component, such as something of the feed member, attached and fixed in a second position on an inner circumference of the Behälteraumahrne.

In a preferred embodiment of an administering device with a retaining element according to the present invention, the fastening device between the retaining element and the container receptacle as described above is formed by an inner and an outer thread. On the holding element at least one at least partially radially extending stop edge is provided, which cooperates in the circumferential direction with at least one axially extending stop rib on the component, such as the feed member. The stop ribs on the component can be provided at the front, the container-facing end, or in a spaced-apart from this end region on the component. In the first position, the holding element is arranged on the component. The container space is introduced by means of a threaded connection between the outer circumference of the container receptacle and the housing inner circumference by means of a rotational movement axially into the housing. The container receptacle is moved towards the component. As soon as the externally threaded segments on the holding element are latched into the internal thread of the container space, the holding element is held in the threaded engagement, while the container receptacle is moved further over the component. As a result, a force in the axial direction is exerted on the holding element relative to the component, which is sufficient to release the connection between the holding element and the component, ie to release the carrier device, which carries the holding element on the component. By a continuous further rotation of the container receptacle relative to the housing, the holding element is now rotated together with the container receptacle relative to the component. The holding element is rotated together with the container receptacle until the abutment edge strikes the holding element against the stop rib on the component. If the container space is rotated further, the holding element is prevented by the stops from rotating and is thus rotated relative to the container space, wherein the outer thread segments of the holding element are rotated within the internal thread of the container receptacle and moves the holding member axially towards the edge of the container, until it hits this one. The holding element thus forms a kind of lock nut, which can be absorbed by the rotational movement of the B ehälteren relative to the device by means of the stop edges and the stop ribs can be tightened. In this position, the retaining element is in the second position and forms a stop against an axial movement of the container within the container receptacle, wherein the container is pressed by the axial component in the rotation of the holding member against the blocking paragraph in the Behälteraufhahme.

In a particularly preferred embodiment, the component is provided as a feed member and the holding element is integrally formed on this. Such a feed member with integrated holding element can be produced for example by an injection molding process. The holding element is attached by means of predetermined breaking points on the feed member, which form the carrier device. If the feed member is inserted into the Behälteraufhahme break the predetermined breaking points, as soon as the holding member is fastened by the fastening means to the container receptacle. After breaking the predetermined breaking points of the fracture region preferably forms the radially inwardly projecting stop edges on the holding element, which cooperate with the stop ribs on the feed member. Depending on the position of the stop ribs on the feed member, it is possible that the holding element is tightened before the feed member hits the plug in the container or after the plug has already been moved by the feed member, z. B. for mixing components in a two-chamber carpule or for a priming process.

In an alternative embodiment of an administration device with a holding element according to the present invention, the fastening device is provided between the holding element and the Behälteraufhahme at a predetermined distance from the edge of the container. In this case, the container with clearance between the blocking paragraph of the Behälteraufhahme and the holding member on the Behälteraufhahme remains axially movable by this distance. When placing an injection needle unit on the receiving area of Behälteraufhahme can then z. B. the cannula of the needle unit against the container, z. B. against the septum, and push the container within the Behälteraufhahme from the receiving area, or from the blocking paragraph. Accordingly, the septum is not pierced when placing the injection needle unit. However, as soon as the feed member acts on the plug in the container during a feed movement, the container is displaced relative to the container receptacle and to the injection needle unit, thereby first piercing the cannula through the septum then the container is impacted at the blocking heel and ultimately the product is administered from the container through the cannula.

BRIEF DESCRIPTION OF THE DRAWINGS

Preferred embodiments of the invention will now be described with reference to the drawings, which are given by way of illustration only and are not to be construed as limiting. Features of the invention which will become apparent from the drawings should be considered individually and in any combination as belonging to the disclosure of the invention. In the drawings:

1 shows a longitudinal section through a distal region of a first embodiment of an administration device according to the present invention in a first position,

Fig. 2: three-dimensional representation of a feed member with a

Retaining element,

3 a shows a detailed view of a first peripheral region of the administration device according to FIG. 1,

3b shows a detailed view of a second peripheral region of the administration device according to FIG. 1,

4 shows a longitudinal section through a distal region of an administration device according to FIG. 1 in an intermediate position, FIG.

5a shows a detailed view of a first peripheral region of the administration device according to FIG. 4,

Fig. 5b: Detail view of a second peripheral portion of a

Administering device according to FIG. 4,

6 shows a longitudinal section through a distal region of the administering device according to FIG. 1 in a second position, FIG. FIG. 7 shows a detailed view of an administration device according to FIG. 6, FIG.

Fig. 8: longitudinal section through an administration device according to the first

Embodiment in a third position,

Fig. 9: Three-dimensional representation of a feed member with a

Retaining element according to a second embodiment of the present invention,

10 shows a longitudinal section through a distal region of an administration device according to the second embodiment and

11 shows a detailed view of the administration device according to FIG. 10.

In the following, a distal end of an administering device is understood to mean the end on which a needle unit can be placed and on which a product is released. The proximal end is the end of the delivery device opposite the distal end, which is typically actuated by the delivery device.

1 shows a first embodiment of an administering device according to the present invention in a first position, which corresponds to the starting position of the device. In Figure 1, the distal portion of the delivery device is shown, while in Figure 8 the delivery device is shown as a whole, but there in a third position.

As can be seen in FIG. 1, the administering device comprises a housing 1, a container receptacle 2 and a receptacle 3 accommodated in the receptacle. Housing 1 has an internal thread 4 which cooperates with an external thread 5 on the outer circumference of receptacle receptacle 2. The housing 1 and the Behälteraumahme 2 are therefore cylindrical and can be screwed into each other by means of the internal thread 4 and the external thread 5, wherein the Behälteraufhahme 2 axially into the housing 1 into shifts. The container 3 is designed as a two-chamber carpule, which has a first chamber 6 with a first component and a second chamber 7 having a second component. The first chamber 6 is provided between a head 8 of the container having a septum-sealed opening and a first plug 9. The second chamber 7 is arranged between the first plug 9 and a second plug 10. In the peripheral wall of the cartridge 3, a bypass 23 is provided which serves to divert a component from the second chamber into the first chamber. To redirect the second component, the second plug 10 is advanced within the cartridge in the direction of the container head 8, wherein the force is transmitted via the component located in the second chamber on the first plug 9, so that this in the direction of the head 8 and in the area of the bypass is moved. By further advancing the second plug 10, the component from the second chamber 7 is transferred via the bypass 23 into the first chamber 6, so that the two components form a mixed product.

The head 8 is received within the Behälteraufhahme 2 in a tapered receiving area 11. An injection needle unit can be placed over the receiving area 11 such that an injection needle extends through an opening of the receiving area, through the septum and the opening of the container into the interior of the first chamber 6 of the cartridge and thus establishes a fluid connection. By further advancing the plugs 9 and 10, the mixed product is administered from the container 3 through the injection needle.

In this embodiment of an administration device, the container 3 is pushed into the container receptacle 2 until a shoulder 12 of the container abuts against a stop edge 13 projecting inwards into the container receptacle in the insertion direction. The stop edge 13 is provided by a tapered portion of the container between the receiving portion 11 for the head and a sleeve portion of the Behälteraufhahme, which serves to receive the container body. Once the container 3 is inserted into the Behälteraufhahme 2, the Behälteraufhahme 2 can be screwed into the housing 1 over a first short distance in the housing 1, as shown in the initial state in Figure 1.

The administering device has an administration mechanism (see FIG. 8), which comprises a feed member 14 which is provided for advancing the plugs 9 and 10. The feed member forms a component to which the container receptacle 2 is axially moved when the container receptacle 2 is screwed into the housing 1, and which serves as a support member for the holding member.

At the feed member 14, a holding element 15 is arranged. The holding member 15 is located at a distal end of the feed member and is detachably attached thereto. The feed member 14 serves as a support member for supporting the holding member 15 in the initial position. In the initial position of Figure 1, the actuating element 2 is located relative to the feed member 14 in a first displacement position in which the holding element 15 is arranged on the feed member 14. In this first displacement position between container receptacle and feed member, the holding element 15 is spaced from the proximal edge 16 of the container 3. Further, the holding element is arranged in front of a formed on the hmenumfang of the container receptacle 2 internal thread 17 and is thus located on a proximal side of the internal thread.

FIG. 2 shows a three-dimensional representation of the feed member 14 and the holding element 15. The holding element 15 is annular and has three external thread segments 18, which are arranged symmetrically on the outer circumference of the annular holding element 15. Between the outer thread segments 18 15 three flat peripheral segments 19 are provided on the circumference of the holding element. The external thread segments 18 protrude in the radial direction over the flat circumferential segments 19 and together form an external thread on the holding element 15. The external thread segments 18 of the holding element 15 can cooperate with the internal thread 17 of the containers. They form with this a self-locking thread. The holding element is preferably made of such material, such as plastic, that the ring is flexible and can be compressed slightly.

The holding element 15 is attached by a plurality of webs 20 on the front side of the feed member 14. In this case, the holding element 15 protrudes beyond the front edge of the feed member 14. The webs 20 form at their transition to the feed member 14 predetermined breaking points, for example, break by a small axial pressure in the direction of the feed member 14 can. The predetermined breaking points are provided by protruding inward in the direction of the feed member 14 edges 21. The edges 21 form a carrier device with which the holding element is supported by the feed member 14.

The feed member 14 has at its distal end on its outer circumference axially extending ribs 22. The ribs 22 are slightly protruded from the outer periphery of the feed member 14. Preferably as many ribs 22 are provided, as webs 20 and edges 21 are provided on the holding element 15.

FIGS. 3a and 3b show two detail sections of the circumference of the administering device in the region of the holding element. In Figure 3a, the housing 1 is shown, in which the container receptacle 2 is inserted. Within the Behälteraufhahme 2, the holding element 15 is located in the starting position in front of the internal thread 17 of the container receptacle 2. An external thread segment 18 of the holding element 15 comes to rest against an inner circumferential surface of the container receptacle 2. In FIG. 3b, the opposing region, that is to say a region offset by 180 degrees from the region from FIG. 3a, is shown. The holding element 15 is attached by means of a web 20 and an edge 21 on the feed member 14. The web 20 is located on a flat circumferential segment 19 of the holding element 15, which is opposite to the inner circumference of the Behälteraufhahme 2. From FIGS. 3 a and 3 b it can be seen that along the diameter of the holding element 15 on one side an external thread segment 18 and on an opposite side offset by 180 ° a flat peripheral segment 19 is provided.

In Fig. 4, the administering device according to the first embodiment of the present invention is shown in a second intermediate position. From the starting position into the intermediate position, the container receptacle 2 has been moved further into the housing 1 by being screwed into the housing by means of the internal thread 4 and the external thread 5. By inserting the Behälteraufhahme 2 in the housing 1, the Behälteraufhahme 2 moves axially on the feed member 14 with the holding element 15. Due to the relative displacement between the Behälteraufiiahme 2 and the feed member 14 and the holding member 15 is displaced axially within the Behälteraufiiahme 2 in the direction of the container 3 until it snaps into the internal thread 17. It can already abut the edge 16 of the container. The segments 18 with the external thread can be easily pressed inward, so that the external thread of the segments 18 is pushed over the internal thread 17 of the Behälteraufiiahme 2. The flat peripheral segments 19 of the holding element 15 can flex flexibly outwards. The internal thread 17 of Behälteraufiiahme 2 and the external thread segments 18 of the holding element 15 can thus form a fastening device for securing the holding element 15 to the Behälteraufiiahme 2.

In FIGS. 5a and 5b, the region of the administering device with the holding element 15 is shown in two mutually opposite cutouts. In FIG. 5 a, the retaining element 15 abuts the edge 16 of the container 3. The external thread segment 18 is engaged in the internal thread 17 of the container receptacle 2, or snapped. It can be seen from FIG. 5a that the externally threaded segments 18 are not connected to the feed member 14 and can therefore flexibly yield radially inwards as soon as they are moved over the internal thread 17 in the feed direction. In Figure 5b, an opposite section of the holding element 15 is shown. The holding element 15 abuts with its distal end against the edge 16 of the container 3 and is attached by means of the web 20 and the edge 21 on the feed member 14. The web 20 is located on a flat circumferential segment 19 of the holding element 15 and is spaced from the internal thread 17 of the container receptacles 2.

Fig. 6 shows the first embodiment of the administering device according to the present invention in a second position, the holding position. Compared to the intermediate position, the Behälteraufiiahme 2 was further inserted into the housing 1 and thus further on the feed member 14 moves, so that it is in a second displacement position. In this case, the holding element 15 is released from the feed member 14. During the movement of the container receptacle 2 via the feed member 14, the feed member 14 is moved into the container 3. However, the holding element 15 is latched in the internal thread 17 or even abuts the edge 16 of the container 3 and thus can not be moved further in the direction of the container. By the axial Shearing force break the predetermined breaking points on the webs 20, so that the holding element 15 is separated from the feed member 14. The holding element 15 is arranged in the holding position in the Behälteraufhahme 2 and forms a holding stop for the container. The container can thus no longer be moved in the proximal direction along the Behälteraufhahme. In the distal direction, the container with the shoulder 12 abuts the stop edge 13 of the container receptacle 2. The container 3 is thus retained in both axial directions within the Behälteraufhahme 2.

FIG. 7 shows a detailed detail of the administering device in a holding position according to FIG. The holding element 15 is released from the advancing element 14 and is held with the external thread segments 18 within the internal thread 17 of the containers 18. The holding element 15 is in the axial direction on the edge 16 of the container 3. The feed member 14 has been displaced relative to the Behälteraufhahme 2 and the container 3 in the distal direction on the plug 10.

In the holding position of the holding element 15, the predetermined breaking points at the edges 21 of the webs 20 of the holding element 15 are broken and the edges 21 protrude radially inward in the direction of the feed member 14. The holding member 15 is in the holding position with its external thread segments 18 in the internal thread 17 of the container receiving 2 stored and is rotated together with the Behälteraufhahme 2 in a further screwing the Behälteraufhahme 2 in the housing 1 relative to the feed member 14. The feed member 14 is axially displaceable in the housing 1, but rotatably mounted. Due to the relative rotation between the Behälteraufhahme 2 with the holding member 15 relative to the feed member 14 and the holding member 15 relative to the feed member 14 is rotated until the inwardly projecting edges 21 of the holding member 15 abut the ribs 22 on the outer circumference of the feed member 14. The ribs 22 thus form a stop for the holding element 15 in the direction of rotation. If the Behälteraufhahme 2 continues to be screwed into the housing 1 and continues to rotate relative to the feed member 14, the holding element 15 is now prevented by the stop of the edges 21 on the ribs 22 at a turning with the container receptacle 2 and is instead rotated relative to the Behälteraufhahme 2 , By the threaded engagement of the externally threaded segments 18 of the holding element 15 with the internal thread 17 of the Behälteraufhahme 2, the holding element 15 is within this threaded connection twisted. As a result of this rotational movement, the retaining element is displaced axially in the distal direction, that is to say in the direction of the container 3, owing to the threaded connection.

As soon as the retaining element 15 rests firmly on the edge 16 of the container, the webs 20 of the retaining element 15 slip over the ribs 22 of the advancing member 14. The container receptacle 2 can thus be further screwed into the housing 1 without the retaining element 15 remaining in the threaded connection 17 , 18, is twisted. The holding element 15 now holds the container 3 safely in the container receptacle. Such tightening of the holding element 15 within the thread 17 is particularly advantageous if the predetermined breaking points on the webs 20 break the holding element 15 already during the import of the holding element 15 in the threaded portion of the internal thread 17 of the Behälteraufhahme 2, but the holding element 15 is not yet Rand 16 of the container 3 abuts.

FIG. 8 shows a longitudinal section through an administration device according to the first embodiment with an administration mechanism in the proximal region of the housing. FIG. 8 shows the administering device in a third position, the mixing position, in which the container receptacle 2 is screwed further into the housing 1. In this case, the container 3 is pushed with the stopper 10 via the feed member 14, so that the plugs 9 and 10 are displaced within the container 3. As soon as the first plug 9 comes to lie in the region of the bypass 23, the second component flows from the second chamber 7 through the bypass 23 into the first chamber 6, wherein the second plug 10 is moved further within the container 3 in the distal direction until it connects to the first plug 9. The component in the first chamber 6 and the component from the second chamber 7 now form a fluid product which can be administered by placing a needle unit on the receiving area 11 of the container receptacle 2. For administering the fluid product from the chamber 6, the administering mechanism of the administering device is actuated.

The delivery mechanism includes, among other things, the advancing member 14 and a trigger button 24 located at the proximal end of the administering device. The feed member 14 is formed like a sleeve and receives a drive spring 25 in itself. At the proximal end, the feed member 14 has two holding hooks 26, with which the feed member 14 is held against the bias of the spring 25 relative to the housing. By the actuation of the release button 24, the retaining hooks 26 can be released from its holder and the drive spring 25 exerts a driving force on the advancing member 14 in the direction of the plugs 9 and 10. The advancing member 14 thus shifts relative to the housing 1 and advances the plugs within the container 3, whereby the fluid product from the first chamber 6 can be distributed.

In Figs. 9 to 11 there is shown a second embodiment of an administering device according to the present invention. Figure 9 shows a three-dimensional view of a feed member 30, at the end of a holding element 31 is arranged. The holding element is designed as a metal ring, projecting from the outer circumference of four retaining prongs 32. The retaining ring 31 can come to lie in a circumferential groove on the feed member 30, from which it can be released by pressure in the axial direction. For this purpose, the retaining ring may also have projections formed on the inner circumference, which engage in the groove. The retaining prongs 32 protrude obliquely to the longitudinal axis of the feed member 30 to the outside of the retaining ring. In this case, the retaining prongs 32 in the proximal direction. In the illustrated embodiment of a retaining element 31 four retaining prongs 32 are shown. However, only two or three retaining prongs or more than four retaining prongs may be provided.

FIG. 10 shows a longitudinal section of the proximal region of the second embodiment of an administration device according to the invention. Components of the administering device which correspond to the first embodiment according to FIGS. 1 to 8 are designated by the same reference numerals. In Figure 10, the Behälteraufhahme 2 is screwed with the container 3 in the housing 1 by means of the internal thread 4 and the external thread 5 in the housing. The Behälteraufhahme 2 is so far into the housing 1 and moved over the feed member 30 that the retaining ring 31 abuts the edge 16 of the container 3. The administering device is in the holding position in this position. As can be seen in FIG. 11, in the holding position, the retaining prongs 32 of the retaining ring 31 engage in the inner peripheral surface of the container support 2. The Behälteraufhahme 2 is preferably made of plastic, so that the metal spikes can be edged into the peripheral surface, since the plastic is softer than the metal. The retaining prongs protrude obliquely in the proximal direction, so that when inserting the feed member 14 into the Behälteraufhahme 2, the outer peripheral surface of the container receptacle 2 along the retaining prongs 32 can slide without them tilt. In a movement counter to the insertion of the feed member 30 into the container receptacle 2, however, the inner peripheral surface of the Behälteraufhahme is moved to the tips of the retaining prongs 32 so that they tilt in the peripheral wall.

In Figure 11, the retaining ring 31 abuts the edge 16 of the container 3. The retaining ring 31 can not be moved further into the Behälteraufhahme 2 together with the feed member, but it is released by the stop at the edge 16 of the feed member 30 and fixed by tilting the retaining prongs 32 on the Behälteraufhahme 2. The container 3 is securely held by the retaining ring 31 in the container receptacle, as it pushes in one direction with its shoulder 12 against the stop edge 13 of the receiving portion 11 of the Behälteraufhahme 2 and pushes in the opposite direction against the retaining ring 31, which upon application of force tilted in this direction in the peripheral wall. The feed member 30 can be moved within the retaining ring 31 in the axial direction, since the retaining ring 31 is held securely by the tilting of the container receptacle 2.

The present invention has been exemplified with reference to two embodiments. In principle, however, other variants of a holding element are conceivable as long as such a holding element is arranged in an initial position on a component of the administering device and is dissolved in a holding position thereof and is connected to the Behälteraufhahme such that there is a holding stop for the container in the Behälteraufhahme forms. In principle, it is also possible to provide another component of the administering device as the advancing member as a support for the holding element, as long as such a carrier in the axial direction of the Container receptacle can be moved to. In this case, the Behälteraufhahme can be moved relative to the carrier and the housing, as is the case in the embodiments shown, or it can be moved relative to the housing and the Behälteraufhahme the carrier.

LIST OF REFERENCE NUMBERS

1 housing

2 container receptacle

3 containers

4 internal threads

5 external thread

6 first chamber

7 second chamber

8 head

9 first stopper

10 second stopper

11 Aufhahmebereich

12 shoulder

13 stop edge

14 feed member / carrier component

15 holding element

16 container edge

17 internal thread

18 male thread segment

19 flat peripheral segment

20 footbridge

21 edge

22 rib

23 bypass

24 release button

25 power spring

26 holding hooks

30 feed member

31 retaining element

32 holding points

Claims

A delivery device for administering a fluid product, comprising: a housing (1), a component (14) mounted in the housing (1), and a container receptacle (2) disposed in or on the housing (1), in which Container (3) is received with the fluid product, wherein the component (14) and the Behälteraufhahme (2) are axially movable toward each other, characterized in that a holding element (15; 31) is provided, which in a first position of the container receptacle (2) relative to the component (14) releasably on the component (14) is arranged and in a second position in which the Container receptacle (2) is moved in the direction of the component (14), of which Component is dissolved and attached to the container receptacle (2) such that it forms a retaining stop for the container (3) in the container receptacle (2). 2. Administration device according to claim 1, characterized in that the container receptacle (2) is axially movable relative to the housing (1) from the first position to the second position. 3. Administration device according to one of the preceding claims, characterized in that the container receptacle (2) has an external thread (5) which cooperates with an internal thread (4) on the housing (1). 4. Administration device according to one of the preceding claims, characterized in that the Behälteraufhahme (2) via the component (14) is movable, wherein it receives the component (14) at least partially in itself. 5. Administration device according to one of the preceding claims, characterized in that the holding element (15; 31) is annular. 6. Administration device according to one of the preceding claims, characterized in that the holding element (15; 31) is mounted in the first position on the outer circumference of the component (14). 7. Administration device according to one of the preceding claims, characterized in that the component (14) is designed as a carrier component with a carrier device (21), wherein the carrier device holds the holding element (15) in the first position on the component and in the second position Retaining element (15) releases. 8. Administration device according to one of the preceding claims, characterized in that the holding element (15; 31) in the second position on an inner circumference of the B ehälter Aufnähme (2) is mounted. 9. Administration device according to one of the preceding claims, characterized in that the holding element (15; 31) by a stop (16) within the Behälteraufhahme (2) from the component (14) is releasable when the Behälteraufhahrne (2) in the direction of the component (14) is moved. 10. Administration device according to one of the preceding claims, characterized in that the holding element (15; 31) in the second position forms a stop which blocks an axial movement of the container (3) relative to the container receptacle (2) in one direction and a blocking shoulder (13) on the Behälteraufhahme (2) is provided which blocks an axial movement of the container (3) relative to the Behälteraufhahme (2) in an opposite direction. 11. Administration device according to one of the preceding claims, characterized in that the holding element (15) has a fastening means (18; 32) which engages in the second position in a counter-fastening means (17) on the Behälteraufhahrne (2). 12. The delivery device according to claim 11, characterized in that the fastening means (18; 32) or the counter-fastening means (19) are designed as latching means or counter-latching means which can be locked together. 13. administering device according to claim 11, characterized in that the fastening means, or the counter-fastening means as external thread (18), or internal thread (17) are formed. 14. Administration device according to the preceding claim, characterized in that the external thread is formed on at least two circumferential segments (18) of the holding element (15). 15. Administration device according to one of claims 13 or 14, characterized in that the outer and inner threads (17, 18) form a self-locking thread. 16. Administration device according to one of the preceding claims, characterized in that the holding element (15) has at least one stop edge (21) which cooperates in the circumferential direction with at least one axially extending stop rib (22) on the component (14). 17. Administration device according to one of the preceding claims, characterized in that the component of a feed member (14) is formed, which is for the administration of the fluid product from the container (3) relative to the container (3) slidably mounted in the housing (1) ,