WO2010083622A1 - Double ozonisation process in ozonised compositions - Google Patents

Abstract

Process for producing ozonised compositions rich in bioactive oxygen through a double ozonisation process comprising three production phases: phase (i): ozonise one or more natural and/or synthetic raw materials, phase (ii): mix the raw materials until formation of a homogeneous mixture, phase (iii): ozonise the homogenous mixture to obtain the ozonised composition. This process for producing ozonised compositions through a double ozonisation process permits furnishing a greater quantity of bioactive oxygen in the final composition thereof and providing a better quality of available bioactive nutrients in the composition thereof. This double ozonisation process technique permits obtaining ozonised compositions which stimulate and promote natural processes of oxygenation, nutrition and cell hydration by virtue of the double ozonisation process permitting the generation of synergy of the raw materials, activating the active principles of the composition thereof, permitting stimulating and activating the natural processes of repair and regeneration of cell tissue in general. These ozonised compositions may be presented in different formats and/or states such as, for example, in the form of oils and/or creams and/or gels and/or ointments and/or syrups and/or jellies and/or capsules and/or tablets and/or drops and/or suppositories and/or injectables and/or sprays and/or sweets, among others.

Description

 DOUBLE OZONIZATION PROCESS IN OZONIZED COMPOSITIONS

DESCRIPTIVE MEMORY

The object of the present invention consists in a process of elaboration of ozonized compositions, rich in bioactive oxygen, made with a double ozonation process, which consists of three phases of elaboration: (i) phase: where one or more materials are ozonized natural and / or synthetic raw materials; (ii) phase: mixing the raw materials to form a homogeneous mixture; and (iii) phase: ozonizing the homogenous mixture to obtain the ozonated composition.

This process of elaboration of ozonized compositions, carried out with a double ozonation process, allows to leave a greater quantity of bioactive oxygen in its final composition and to contribute a better quality of bioactive nutrients available in its composition, which allows to favor and stimulate the natural processes of oxygenation, nutrition and cellular hydration, activating the natural processes of repair and regeneration of cellular tissue in general. This process of elaboration carried out with the double ozonation process, allows to obtain ozonized compositions that stimulate and favor the natural processes of oxygenation, since it allows to leave a greater quantity of bioactive oxygen, ozone monocytes, ozonides, oligomeric ozonides, peroxides and hydroperoxides available in the final composition. In addition, this technique of double ozonation process generates a synergy of the raw materials activating the active principles of its composition, providing a better quality of bioactive nutrients available in its final composition; What allows to promote and stimulate cellular nutrition processes, activating the natural processes of the repair and regeneration of cellular tissue in general.

These ozonated compositions are composed of one or more natural raw materials and / or ozonized synthetics, and / or the combination of both which can be presented under different formats and / or conditions such as, for example, in the form of oils and / or creams and / or gels and / or ointments and / or syrups and / or jellies and / or capsules and / or tablets and / or drops and / or suppositories and / or injectables and / or spray, among others.

FIELD OF THE INVENTION

The present invention has its application preferably in the cosmetic field, in the production of ozonized compositions, made from one or more natural and / or synthetic ozonized raw materials, or the combination of both where the natural raw materials may be of vegetable origin and / or its derivatives; and / or of animal origin and / or its derivatives; and / or of mineral origin in its different states and / or its derivatives; natural and / or synthetic oils and their derivatives, natural and / or synthetic gels and their derivatives and / or materials synthetic premiums in their different states such as, for example, preservative and / or preservatives and / or excipients.

These ozonated compositions are subjected to a double ozonation process in their production process, which consists of 3 phases; said compositions may be presented in different formats and / or conditions such as, for example, in the form of oils and / or creams and / or gels and / or ointments and / or syrups and / or jellies and / or capsules and / or tablets and / or drops and / or suppositories and / or injectables and / or spray, among others.

BACKGROUND OF THE INVENTION Ozone is known, in the state of the art of ozone therapy, for achieving the following therapeutic effects by itself.

1. Ceiuiai oxygenation

2. It generates an increase in cellular energy by stimulating mitochondrial ATP

3. Stimulates the vital processes of cellular metabolism 4. Stimulates the self-regulation of cell metabolism

5. Activate the cellular GHS, restoring, repairing and regenerating the cells

6. Blood microcirculation increases

7. It stimulates cellular hydration, improving the retention of water inside it, increasing its humidity for a longer time. 8. It stimulates the enzymatic processes of the cells (anti-free radicals, anti-aging, anti-aging)

9. It is sterilizing for its bactericidal, fungicidal, germicidal and antiviral capacity

10. Immune system stimulant

11. Hepatic system regulator 12. Pancreatic system regulator

13. Repairing and regenerating the cellular tissue.

14. It is a powerful antioxidant

15. That ozone is an unstable gas and that it becomes oxygen, among others.

At present, as regards the state of the art, it is known from the ozonation patents of oils of vegetative origin. ozonated; where ozone is subjected to a single oil, under a single ozonation process, to the point of saturation of the oils, reaching the degree of solidification of it. Ozonization processes of oils as part of the state of the art, which reach the state of saturation of the oils; They present the following disadvantages:

1. They make them very stable, making chemical bonding with other raw materials difficult for the preparation of a composition. 2. They raise the pH of the oil a lot to the point of having to process it to lower its pH.

3. In the therapeutic effects of its topical application, they cause such a sudden and severe reaction in the dermal tissue, which cause burning, redness and itching in the skin.

4. And in the therapeutic effects of its oral intake, either in oils or in capsules; in some individuals it causes vomiting and / or nausea.

In attention to the aforementioned, there is no knowledge of a double ozonation process that favors and stimulates the natural processes of oxygenation, nutrition and cellular hydration simultaneously, which allows to activate the natural processes of repair and regeneration of cellular tissue in general. As regards the state of the art in cosmetic compositions, there are no known compositions that oxygenate the cellular tissue. And on the other hand, the cosmetic compositions either hydrate the skin or nourish it, but there are no cosmetic or dermatological compositions that hydrate and simultaneously nourish the dermal tissue. Therefore, the present invention of ozonized compositions, elaborated with a double ozonation process, allows solving the problems of: a) Generating ozonated compositions that allow to oxygenate the cellular tissue. b) Generate ozonated compositions that allow to simultaneously nourish and hydrate the cellular tissue. c) Generate ozonized compositions composed of several raw materials. d) Generate ozonized compositions composed of a wide range of raw materials extracted from the different realms of nature e) Generate ozonated compositions composed of a wide range of synthetic raw materials f) Generate stable ozonized compositions, with a good chemical cohesion of the materials raw of its composition. g) Generate ozonated compositions with a balanced pH. h) Generate ozonized compositions whose therapeutic effects in topical application, do not cause such a sudden and severe reaction in the dermal tissue, therefore, do not cause burning, redness and itching in the skin. i) Generate ozonized compositions of capsules and / or syrups and / or oils intended for oral intake; that do not provoke therapeutic effects of nausea and / or vomiting, j) Generate ozonized compositions, which can be presented under different formats and / or conditions such as, for example, in the form of oils and / or creams and / or gels and / or ointments and / or syrups and / or jellies and / or capsules and / or tablets and / or drops and / or suppositories and / or injectables and / or spray, among others. k) Generate ozonized compositions composed of natural and synthetic raw materials DESCRIPTION OF THE INVENTION

The present invention consists of a process for the preparation of ozonated compositions carried out with a double ozonation process, a technique consisting of 3 phases: (i) phase: where one or more raw materials of a parucuiai composition are ozonized, individually and separately, without allowing these ozonized raw materials to saturate to the degree of solidification; (ii) phase: mix the raw materials until a homogeneous mixture is formed; (iii) phase: where the homogenous mixture is subjected to ozonation to obtain the ozonated composition. This technique for the preparation of ozonized compositions carried out with a double ozonation process makes it possible to obtain ozonized compositions with a greater quantity of bioactive oxygen, ozone monocytes, ozonides, oligomeric ozonides, peroxides and hydroperoxides available in the final composition. Technique that allows to favor and stimulate the natural processes of cellular oxygenation, nutrition and hydration, thus enabling the natural processes of repair and regeneration of cellular tissue in general.

These ozonized compositions, product of the present invention, are composed of one or more natural and / or ozonized synthetic raw materials and / or the combination of both; those which can be presented in different formats and / or states, for example in the form of oils and / or creams and / or gels and / or ointments and / or syrups and / or jellies and / or capsules and / or tablets and / or drops and / or suppositories and / or injectables and / or spray, candies among others.

DESCRIPTION OF THE PROCESS OF ELABORATING THE INVENTION (i) PHASE:

The first phase of the process of preparing the ozonated compositions consists in submitting to the first ozonation process of the invention, subjecting to ozonation one or more raw materials of natural and / or synthetic origin as ingredients constituting a particular composition; ozonation individually and separately, to one or more raw materials of the formula, which will cause by the reaction of the ozone with the raw material, an activation of the active ingredients of each of the nutrients contained in each raw material , which will be available to make synergy with the other constituent ingredients of a particular composition, when it passes to the (ii) phase

This first phase of the invention consists of ozonation to one or more raw materials of the composition, ozonizing them individually and separately; subjecting it to react with ozone to the point of producing a mixture of ozone gas in the matrix of the raw material, causing a rich mixture of monocytes of ozone, ozonides, oligomeric ozonides and various products rich in active oxygen, of the peroxide type, hydroperoxides bioactive oxygen; but without reaching the degree of saturation; that is, that the raw material maintains its unsaturated grade. This procedure can be achieved with the different types of raw materials of natural origin, the vast majority of which are in an unsaturated state and / or their derivatives; and / or synthetic unsaturated raw materials and / or their derivatives; which will be exposed to the bubbling of ozone in dosages gammas / hours, whose dosages are calculated according to two items: (a) the degree of saturation of the raw material, so that when exposed to the bubbling of ozone, maintain its unsaturated state ; and (b) according to the degree of the PH that the raw material possesses; so that this when exposed to the bubbling of ozone does not increase the PH degree to undesirable ranges, thus achieving a balanced PH

In this first phase of the process of preparing ozonated compositions; consists of placing the raw material individually in a sterilized container and subjecting it to the bubbling of the ozone, (when the raw materials are in a liquid state); subjecting it to the bubbling of the ozone through a sterile probe introduced up to the base of the container, connected to an ozone generating equipment; which is fed from an oxygen tube for medicinal use, which generates ozone gas according to the gamma / minute dosages ranging from 1 gamma to 300 gammas per minute and the times of exposure of the ozone bubbling in a particular raw material , ranging from an exposure from 1 minute to 10 hours of ozone gas exposure; whose dosages of gammas / minutes and times of exposure to the ozone gas mixture are to be calculated depending on the PH grade of the raw material, with the purpose of achieving a balanced PH; and according to the degree of saturation of the raw material, so that it maintains its unsaturated state.

When the raw material is in a colloidal state or in the form of a gel; This must be whipped gently while it is being subjected to the bubbling of the ozone, so that the ozone gas mixture is homogeneously dissolved in the matrix of the raw material. And if this raw material will be in solid state; first it has to be sprayed, and then dissolved in a solvent of aqueous or oily origin, before being subjected to this first ozonation phase.

In this first phase of the invention, ozonized raw materials with the following characteristics are obtained: 1. Raw materials rich in peroxides, hydroperoxides, which allows obtaining raw materials free of bacteria and / or fungi and / or germs and / or parasites and / or virus.

2. Raw materials rich in ozone monocytes, ozonides, oligomeric ozonides, which will stimulate and activate the enzymatic processes of each of the active ingredients of the nutrients contained in each raw material. 3. Raw materials rich in active oxygen, which causes the activation of the bio-active oxygen available for cellular oxygenation. 4. Unsaturated raw materials Io that allows me to have better availability of chemical bond with other raw materials.

5. Raw materials with a PH balanced according to the needs required by the therapeutic benefits expected by the composition. 6. Raw materials with better tolerance in the application of topical use; either for creams and / or gels and / or oils and / or ointments and / or spray formats, among others.

7. Raw materials with better tolerance in oral intake, either for formats of oils and / or syrups and / or jellies and / or capsules and / or tablets and / or drops, among others.

8. Raw materials exposed to ozonation with wide ranges of gammas / minutes according to the specific needs of each raw material.

(ii) PHASE:

The second phase of the elaboration process of the invention consists of mixing the raw materials of the composition, both ozonized raw materials, as well as non-ozonated raw materials, until a homogeneous mixture is formed; where the raw materials as ingredients of a particular composition, are mixed, whipped and centrifuged; process by which they tend to lose the ozone and active oxygen of their ingredients, but which in turn allows to establish in this second process of elaboration of the present invention, the following benefits: a) Homogeneous compositions with a good cohesion of the materials premiums, since it allows to establish better chemical bonds with the different raw materials of a particular composition b) Compositions rich in bioactive nutrients, since it causes a synergy between the active principles of the different nutrients that make up the different ingredients of this particular composition, since the raw materials to be subjected to the first ozonation process, cause a synergistic effect of their nutrients, because the reactive ozone and enhances the active ingredients of each of the constituent nutrients in each raw material, which in this second phase of the invention is going to generate a synergy with the active principles of nutrients activated by ozone; with the other raw materials, which are part of the constituent ingredients of a particular composition, thus making it possible to obtain compositions rich in bioactive nutrients available in the final composition c) These compositions rich in bioactive nutrients are of a great nutritional contribution available at the level cellular, which allows to promote and stimulate the process of cellular nutrition.

(iii) PHASE:

The third phase of the process of preparing the invention consists in subjecting the composition to the ozonation process; which consists of placing in a container sterilized to the composition, which is whipped gently while this composition is subjected to the bubbling of the ozone gas through a sterile probe introduced to the base of the container, connected to an ozone generating equipment, which is fed from a tube of oxygen for medicinal use, which generates ozone gas according to gamma / minute dosages ranging from 1 gamma to 120 gammas per minute, with an exposure of ozone bubbling ranging from 1 minute to 3 hours of ozone exposure; according to the specific therapeutic needs of each composition With this third phase of the invention, which consists in submitting to a double ozonation process allows us to obtain ozonized compositions with the following characteristics: a) Ozonized compositions with a higher concentration of peroxides, hydroperoxides in each particular composition, which allows to obtain compositions with bactericidal characteristics, and / or fungicides and / or germicides and / or antivirals. b) Ozonized compositions with a higher concentration of monocytes of ozone, ozonides, oligomeric ozonides, which will cause the reactivation of the enzymatic processes of each of the active ingredients that are present as a nutrient of a particular composition. c) Ozonized compositions rich in active oxygen, which causes the activation of the bioactive oxygen available in the final composition, which allows the stimulation of the cellular oxygenation process since it stimulates and reactivates the natural enzymatic processes of cellular biological respiration. d) Ozone compositions rich in bioactive oxygen, which allows me to use bioactive oxygen as the vehicle for the active principles of nutrients inside the cell, allowing a better stimulation of the absorption of these in the process of cellular nutrition , since it stimulates and reactivates the natural enzymatic processes of cellular biological respiration and cellular nutrition simultaneously. e) Ozonized compositions rich in bioactive oxygen, which allows cellular oxygenation and nutrition simultaneously, stimulating and naturally improving the vital functioning of the body's cells; Which leads us to optimize cellular operation. f) Ozonized compositions rich in bioactive nutrients and bioactive oxygen that by stimulating cell nutrition and oxygenation; they allow to improve the vital functioning at the cellular metabolism level, helping to stimulate and reestablish the capacity of repair and regeneration at the cellular level. g) Ozone compositions rich in bioactive nutrients and bioactive oxygen that allow stimulating and reestablishing the repair and regeneration capacity at the cellular level S causing stimulation of the repair and regeneration of the different organs of the body, h) Ozonized compositions rich in bioactive nutrients and bioactive oxygen that allow to stimulate the repair and regeneration of the organs of the body; Those that promote the stimulation of the repair and regeneration of the feedback process of the different systems of human metabolism. i) Ozone compositions rich in bioactive nutrients and bioactive oxygen that allow stimulating the repair and regeneration of the feedback process of the human metabolism, allowing to recover the health in an integral and natural way.

On the other hand, these ozonized compositions, the product of the double ozonation process, are compositions rich in monocytes of ozone and active oxygen, which thanks to the double ozonation process, not only generates a synergy of the active ingredients of their natural ingredients activated by the first ozonation process, but also has a greater amount of ozone monocytes and active oxygen available in its final composition, where in addition to stimulating cellular oxygenation for its high concentrations of bioactive oxygen available at the cellular level, causing the increase and Activation of bioactive oxygen so that it is used as a vehicle for the active principles of nutrients inside the cell, thus facilitating a better absorption of nutrients and even inside the nucleolus of the cell (in those compositions that, for example, contain spirulina, chlorella among others, for its high content of DNA and RNA) ; stimulating the enzymatic processes of nutrition and cellular oxygenation.

Therefore, this technique of the double ozonation process allows to stimulate in a natural way the processes of the repair and regeneration of the cellular tissue; through the nutrition, oxygenation and hydration of the cellular tissue, causing a synergy in the second ozonation process, stimulating and reactivating the natural enzymatic processes of cellular biological respiration and cellular nutrition simultaneously, allowing to improve in a natural way the vital functioning of the cells, restoring their capacity to repair and regenerate themselves at the cellular level and therefore at the metabolic level; recovering thus, the integral health of the whole organism and the natural form.

On the other hand, this technique of double ozonation process allows solving the existing problem in the state of the art; where in the case of patents for ozonated oils, the oil is ozonized to the point of saturation of the oils; process that brings some disadvantages, (which are described in the background of the invention) to propose in the present invention a double ozonation process that consists of ozonation of the oils to the point of subjecting them to react with ozone gas to the point of produce in the matrix of raw materials, ozonides, oligomeric and various ozonides products rich in active oxygen, such as peroxides and hydroperoxides, etc., but without altering their degree of saturation and maintaining a relatively balanced PH; allowing solving the problems of the state of the art. In addition, with this procedure the different types of oils of natural origin and / or unsaturated synthetics can be processed; and / or with different raw materials of natural and / or synthetic unsaturated origins, according to their chemical bonding capacity, that is, according to their degree of saturation; and your PH; as for example, in a 1 liter exposure of oil from an exposure of 5 gammas / minutes to 300 gammas / minutes, for an exposure ranging from 1 minute to 10 hours of exposure, according to the degree of saturation of the oil and its PH, without letting it saturate, which allows oils with this technique of double ozonation, present the following characteristics: a) Better capacity to establish more chemical bonds and better cohesion with other raw materials used as ingredients for the preparation of a particular composition; b) Balanced pH of the raw material is achieved; c) It is ozonated until the desired pH is reached (according to the PH of the Oil and / or raw material); d) It is possible to attenuate the abrupt and violent reactions without provoking burning, redness of the skin and / or itching, achieving the effects of oxygenation and cellular nutrition, which allows to stimulate the repair and natural regeneration of the cellular tissue of the dermis (in the dermis). case of the compositions for topical use); e) It is possible to attenuate the therapeutic effects of its oral intake, either in capsules or in tablespoons; attenuating the vomiting and / or nausea in the great majority of individuals, which allows to stimulate the repair and natural regeneration of the cellular tissue in general and the recovery of the basal metabolism feedback process, therefore, the recovery of the health in general.

As regards the ozonized compositions, as a product of the present invention, they can be composed of one or more raw materials of natural origin and / or their ozonized derivatives and / or in their different states; and / or one or more raw materials of synthetic origin and / or in different ozonized states, which contain as ingredients in any proportion and in any combination according to their particular composition, which will be designed for a specific therapeutic purpose.

The raw materials that are part of the ingredients of the ozonized compositions of the present invention, which are of natural origin in any of their states and / or derivatives, contain high concentrations of active principles activated by the first ozonation process, which are highly nutritive at cellular level, which allows to stimulate cellular nutrition since it leaves available bioactive nutrients for nutrition cellular, which when subjected to this double ozonation process (technique that on the one hand, in its first phase of ozonation) causes the activation of the active ingredients of each of the nutrients contained in each ingredient and then, of a second phase of the invention, said ozonated ingredients whose nutrients and active principles are already activated, when being taken to the second phase of the process of making the composition, where the raw materials as ingredients of a particular composition are mixed, shaken and centrifuges for obtaining a composition; they tend to lose the ozone and active oxygen of their ingredients, a process that when this composition is subjected to a second ozonation process (in the third phase of the invention) causes a new reactivation of the active oxygen available in the final composition and the increase of the bioactive oxygen, which on the one hand allows cellular oxygenation and on the other hand, the use of bioactive oxygen as a vehicle for bioactive nutrients allowing the penetration of nutrients, inside the cell and even inside the nucleolus in its trip to DNA repair, when the composition is rich in DNA and RNA such as, for example, in the compositions containing spirulina, chlorella, among others, thus facilitating a better absorption of nutrients, which through this double ozonation technique , it allows to stimulate the natural processes of the repair and regeneration of the cellular tissue, by means of oxygenation, nutrition and hydration. n simultaneous cellular tissue, leaving a younger, new, soft and smooth in the case of compositions format creams and ointments skin for topical use. The same applies to all types of cellular tissue, in their different formulas of ozonated compositions, which are designed according to certain therapeutic objectives and administered in different presentation formats; as for example the capsules, syrups, jellies, drops and tablets among others for oral intake.

Therefore, the therapeutic benefits obtained from the ozonized compositions, as a product of the present invention, when the natural and / or synthetic raw materials subjected to a double ozonation process are processed; process described in the present invention; it allows us to obtain compositions that give us the following characteristics: (A) On the one hand, the active principles of the nutrients contained in the different raw materials will be exacerbated in the first phase of the invention; (B) On the other hand, which when taken to the second phase of the invention, causes a synergy of the nutrients of all the raw materials used as ingredients of a formula of a particular composition;

(C) And on the other hand, the composition to be taken to the last phase of the invention, ie in the second ozonation process, a second synergy is generated in this composition, in whose composition are already active the active principles of the nutrients of the raw materials (first phase), is reactivated with the active oxygen and ozone monocytes obtained with the third phase of the process of elaboration of the invention, thus achieving Ia reactivation of the active ingredients of the final composition; What allows to achieve the following therapeutic benefits;

• Ozonated compositions that offer cellular oxygenation.

• Ozonated compositions that simultaneously offer nutrition and hydration of the cellular tissue.

• Ozonized compositions that offer better and greater stimulation of the repair and regeneration of the cellular tissue.

• Ozonized compositions that offer greater and better stimulation of the increase of the cellular ATP energy, than other ozonation techniques. • Ozonized compositions that offer better and greater stimulation of the increase of the microcirculation and blood supply.

• Ozonated compositions that offer greater and better stimulation of cellular enzymatic functions.

• Ozonated compositions that offer greater and better stimulation of cellular metabolic processes.

• Ozonated compositions that offer greater and better stimulation of the processes of repair and regeneration of organs.

• Ozonized compositions that offer greater and better stimulation of the processes of repair and regeneration of the feedback process of the metabolism systems in general.

• Ozonized compositions that offer a better stimulation of the feedback processes of the metabolism systems in general, allowing to recover the health in an integral and natural way.

• Ozonized compositions that offer greater and better protection against pollutants of internal origin product of basal metabolism.

• Ozonized compositions that offer greater and better protection of pollutants from the external environment.

• Ozonized compositions that offer greater capacity to neutralize free radicals. • Ozonated compositions that offer better stimulation of cell tissue renewal.

• Ozone compositions more effective to slow cell aging.

• Ozonized compositions that offer greater and better stimulation of the natural production of collagen and elastin. • Ozone compositions more effective in cleaning and sanitizing due to the sterilizing, bactericidal, germicidal and antiviral properties provided by ozone. • Ozonized compositions that offer better and greater control and / or regulation of the secretion of the sebaceous glands.

• Ozonized compositions that offer sun protection since it protects against ultraviolet rays A and B, due to its high ozone content. • Ozonized compositions that offer greater and better increase in cellular hydration and therefore greater and better humidification, for longer.

• Ozonized compositions that offer a greater and better attenuation of skin spots due to the properties provided by ozone.

• Ozonized compositions that offer greater and better stimulation of the attenuation of wrinkles and expression lines.

• Ozonized compositions that offer a better skin texture leaving it smoother and smoother, (in the case of cosmetic compositions) among others.

EXAMPLES OF OZONIZED COMPOSITIONS BASED ON THE DIFFERENT RAW MATERIALS OF ITS COMPOSITION

These ozonized compositions containing in any combination and proportion one or more naturally occurring ozonized raw materials, such as for example one more ozonated oils and / or one or more algae and / or one or more plants and / or one or more herbs and / or one or more amino acids and / or one or more ozonized vitamins; and / or one or more ozonized synthetic raw materials, such as, for example, preservatives and / or preservatives and / or excipients; Ozonized compositions that must be subjected to a double ozonation process, carried out as in the described invention.

Ozonized compositions containing as raw materials, the use of vegetable and / or animal and / or synthetic oils, among others, it is suggested that oils containing a defined therapeutic effect be used, either for topical use on the skin, as For example, it is recommended and without this list is exhaustive, ozonized jojoba oil, ozonated avocado oil, ozonized damask oil, ozonated almond oil, emu oil, ozonized fruit oil, ozonized rosehip oil, liquid petrolatum ozonized among others, for the use of compositions whose formulas have a format of creams and / or ointments and / or gels for topical use and / or cataplasms, spray, among others.

On the other hand, we can also see ozonized compositions in different formats, such as, for example, containing as raw materials, among others, the use of oils of vegetable and / or animal origin and / or synthetic whose characteristics and properties are related to uses therapeutics via oral ingestion, as for example, without this enumeration being exhaustive, ozonized soybean oil, ozonized castor oil, ozonized cod liver oil, ozonized sardine oil, among others, either for its format in liquid form to be administered orally by spoonfuls; and / or in its encapsulated oil format.

Also, we can find ozonized compositions whose raw materials are based on vegetables in general and / or one or more of its parts, as for example, without this enumeration being exhaustive, the stem and / or the root and / or the stem may be used. bark and / or the seed and / or the gel and / or Ia and / or the leaves and / or the fruits and / or their derivatives and / or their extracts, of the different species of vegetable varieties that provide the different benefits therapeutic has on Ia health in general. As for example, ozonation is recommended as raw materials, without this enumeration being specific, aloe vera plant specifically aloe vera gel, ginseng extract, chamomile extract, green tea leaf extract, gel of different varieties of cactus, essential oils and / or aromatic flowers, sesame seeds and / or its oil, flax seed and / or its oil, chia seed and / or its oil, fruit oil, flower oil as lavender, rose etc ., among others.

Another example of ozonized compositions that are based on Gei Aloe Vera as they are highly nutritive ozonized compositions with all the therapeutic benefits provided by aloe vera gel, whose active ingredients that aloe vera gel has for the regeneration of tissue, repairing the cell tissue, moisturizing very dry skins for its powerful moisturizing capacity and for all the qualities offered by aloe vera gel in general, as anti-inflammatory, analgesic, antibacterial and healing, among other qualities.

Also, we can obtain ozonized compositions whose raw materials are based on algae that can come from fresh or salt water, where the pulverized and / or natural algae and / or any of its derivatives and extracts are used, where it is recommended, for example, without that this enumeration is exhaustive, kelp of Asian centella, chlorella, spirulina, among others., for its great nutritive contributions and DNA and RNA contained in the raw material of its composition, which, in addition, allows to exacerbate the activation of the Sod of the spirulina which chemical reaction with ozone and the large amount of ozonides allows the uptake of free radicals as a beneficial action, in addition to causing the stimulation of the vital processes of cellular metabolism, which allows to stimulate in a natural way, the capacity of repair and cellular regeneration. It should be mentioned that all those algae that are used in pulverized form, will be dissolved in solvents of aqueous or oily or colloidal type to achieve the state of liquid and / or gel to be taken to the ozonation process.

Also, we can find ozonized compositions based on different types of nutrients extracted from natural raw materials of vegetable origin and / or animal origin and / or of synthetic origin, nutrients as for example and without this enumeration being exhaustive, synthesis of active principles and / or vitamins and / or proteins and / or amino acids in any of their derivatives and / or in any presentation and / or condition, such as, for example, without numbering is taxative, essential and non-essential amino acids, such as L-lysine, L-arginine, L-glycine, taurine cysteine, among other amino acids and / or trace elements, calcium, selenium, zing, shark cartilage, oyster calcium among others and / or the variety of vitamins such as vitamin A, vitamin B 1, 6, 5, 12, 15, 17, vitamin C, vitamin P ₁ vitamin K among others. Where we can also find ozonized compositions, based on ingredients of mineral origin in its different states, organic and inorganic, such as, for example, without this numbering is exhaustive, trace elements, such as selenium, calcium, magnesium, zing, manganese and / or minerals inorganic micro particles like quartz, lapis lazuli, jade, gold, diamond, cesium, among others. Also, it is possible to find ozonized compositions with different combinations of raw materials, such as, for example, a composition containing one or more ozonated essential oils and / or one or more component of the ozonized vegetable kingdom, such as, for example, without this numbering being exhaustive , ozonized aloe vera gel and / or ozonated spirulina and / or one or more ozonized vitamins such as for example vitamin E, A, D and C and / or one or more ozonized amino acids such as L-lysine, L-arginine, L-glycine , taurine and / or one or more ozonized synthetic raw materials such as preservatives, preservatives and excipients. These ozonated compositions must be subjected to a double ozonation process, as described in the present invention, such as, for example, ozonation of 1 liter of a raw material to an exposure of an ozone bubble that can range from 5 gammas / minutes to 300 gammas / minutes for an exposure ranging from 1 minute to 10 hours of exposure, according to the degree of saturation of the raw material and its PH degree, without letting it saturate.

EXAMPLE OF APPLICATION Ozonated cosmetic composition in gel cream format, subjected to a double ozonation process based on aloe vera gel, ozonized jojoba oil, ozonated avocado oil, spirulina, vitamin E, preservatives and excipients required.

INGREDIENTS% p / p

AQUA 79.222 OZONIZED JOJOBA OIL 8,000

BIOSACCHARIDE GUM-1 3.000

DICAPRYLYL CARBONATE 2.000

PERSEA GRATISSIMA OIL 2.000

CYCLOMETHICONE / DIMETHICONE CROSSOLYMER 2,000 SODIUM POLYACRYLATE 1,500

TOCOPHERYL ACETATE 1,000

PROPYLENE GLYCOL 0.460 DIAZOLIDINYL UREA 0.300 SPIRULINA MAXIMUM EXTRACT 0.300 METHYLPARABEN 0.110 BHT 0.100

ALOE ARBORESCENS EXTRACT 0.005 PROPYLPARABEN 0.003

EXAMPLE OF ELABORATION OF A COMPOSITION (i) PHASE OF THE INVENTION: Where the technique of the double ozonation process begins with the first phase of the invention; that is, the first ozonation process: which begins with the ozonization of the raw materials individually and separately, in this case the jojoba oil and the avocado oil (persea gratissima oil) at an ozone bubble exposure at 120 gammas / minutes for 3 hours of exposure per liter of oil. Obtaining the ozonized raw materials necessary for the particular composition. (II) PHASE OF THE INVENTION:

Once the raw materials of the composition are ozonized, it is subjected to the second phase of the invention; where the ingredients of the formula as raw materials will be subjected to the process, mixing the ozonized and non-ozonated raw materials until generating a homogeneous mixture, which in this case will be carried out in 3 steps of incorporation of the raw materials; until achieving a homogeneous composition. FORMULA

CROSSOLYMER )

CROSSOLYMER)

Equipment: Stainless Steel Reactor with homogenizer

• Ensure cleaning and sanitizing of equipment and utensils to be used during the process.

• In stainless steel reactor add Step A, stir until total homogenization. It should form a viscous gel.

Then add to the previous mixture one by one the components of Step B with strong agitation and touches of homomixer.

000046 Cetiol CC

B HT

Jojoba oil

Avocado oil

Vitamin I ≡

Then add the components of Step C. Homogenize for 15 minutes more and take sample to quality control.

• Once the batch has been approved, discharge by passing the product through mesh or stainless steel sieve in suitable containers and correctly labeled. (III) PHASE OF THE INVENTION:

Once the homogeneous composition is obtained, it is submitted to the third process of the invention; that is, to the second ozonation process, where this homogeneous composition will be subjected to 60 gammas / minutes for an ozone bubble exposure for 10 minutes.

Once obtained the ozonized cosmetic composition as a product of the invention, it is packaged and labeled in Airless containers which are sealed in vacuum and its emptying is performed by a dispenser, which keeps the composition permanently sterile until its last application, thus maintaining in stable form, all the characteristics described in the present invention, and even the bactericidal, fungicidal, germicidal and antiviral characteristics of the composition.

Claims

1. Process of elaboration of ozonized compositions, CHARACTERIZED because they are elaborated with a double ozonation process, based on one or more ozonized natural and / or synthetic raw materials. 2. Process for preparing ozonated compositions, according to claim 1 CHARACTERIZED because the double ozonation process consists of three processing phases; (i) Phase: ozonation of one or more raw materials; (ü) Phase: mix the raw materials to form a homogeneous mixture; (iii) Phase: ozonizing the homogeneous mixture to obtain the ozonated composition. 3. Process for the preparation of ozonated compositions, according to claim 2, characterized in that the (i) phase consists of subjecting one or more raw materials to ozonation; ozonizing separately, to one or more raw materials of the composition. 4. Process for the preparation of ozonized compositions, according to claim 3, characterized in that in Ia (i) phase, the raw materials can be; one or more raw materials of natural origin, of synthetic origin, or a combination of both. 5. Process for preparing ozonated compositions, according to claim 4 CHARACTERIZED because in the (i) phase, the raw materials that are in solid state, must be pulverized and dissolved in a solvent before being ozonated. 6. Process for preparing ozonated compositions according to claim 5, wherein the solvents can be of the aqueous type and / or the oil type. 7. Process for preparing ozonized compositions, according to claim 6 CHARACTERIZED because in the (i) phase, it consists of placing the raw material in a sterilized container and subjecting it to bubbling through a sterile probe introduced to the base of the container, connected to an ozone generating equipment, (which is fed from an oxygen tube for medicinal use), that generates ozone according to the gamma / minute dosages ranging from 1 gamma to 300 gammas per minute and the times of exposure of the bubbling of ozone gas in a particular raw material range from an exposure of 1 minute to 10 hours of ozone exposure; ozonation ranges in gammas / minutes according to the specific needs of each raw material. 8. Process for preparing ozonized compositions, according to claim 7, CHARACTERIZED because in Ia (i) phase, it is carried out until a mixture of the ozone gas is produced in the matrix of the raw material, according to two items: (a) according to the degree of saturation of the raw material, so that when it is ozonated it maintains its unsaturated state; What allows to obtain raw materials with greater and better availability for the chemical bond with other raw materials, which will be part of a particular composition; (b) according to the grade of the PH that possesses the raw materials, so that, when exposed to the bubbling of the ozone, maintain a balanced pH, according to the needs required by the therapeutic benefits expected by the composition. 9. Process for the preparation of ozonated compositions, according to claim 8, characterized in that in Ia (ii) phase, the raw materials of the composition are mixed, both the ozonized raw materials and the non-ozonated raw materials, to form a homogeneous mixture. 10. Process for the preparation of ozonized compositions, according to claim 9, characterized in that in Ia (iii) phase, it consists of placing the composition in a sterilized container, which is whipped gently while being subjected to bubbling of the ozone gas, to through a sterile probe, introduced up to the base of the container, connected to an ozone generating equipment (which is fed from an oxygen tube for medicinal use), which generates the ozone gas according to the gamma / minute dosages ranging from 1 gamma to 120 gammas per minute and the exposure times of ozone gas bubbling in a particular composition, ranging from a 1-minute exposure to 3 hours of ozone gas exposure; ozonation ranges in gammas / minutes that go according to the specific needs of each composition. 11. Process for the preparation of ozonized compositions, according to claim 10, characterized in that the (iii) phase is carried out until a mixture of the ozone gas is produced in the matrix of the composition, being able to modify it or not; your PH, according to the therapeutic need and / or according to the application format. 12. Process for the preparation of ozonated compositions, according to claim 11, characterized in that the (iii) phase can be carried out until the ozone saturation in the composition is caused. Process for preparing ozonized compositions, according to claim 12, characterized in that they are made from one or more raw materials of natural origin and / or of synthetic origin or the combination of both in any proportion and in any combination according to their particular composition; Ia which will be designed for a specific therapeutic objective. 14. Process for the preparation of ozonized compositions, according to claim 13, CHARACTERIZED because they are packaged in empty containers, the dosage of which allows maintaining the ozone contained inside the composition; without letting it escape, in the process of extracting the composition. 15. Ozonated compositions, prepared according to claim 14, CHARACTERIZED because the content of the composition remains sterile; in the process of extracting the composition. 16. Ozonated compositions, prepared according to claim 15, characterized in that they are composed of dissolved bioactive oxygen in their composition. 17. Ozonated compositions, prepared according to claim 1, characterized in that they are composed of ozone, ozonides, ozone monocytes, oligomeric ozonides, peroxides and hydroperoxides dissolved in their composition. 18. Ozonated compositions, prepared according to claim 15, characterized in that they are saturated with ozone in their composition. 19. Ozonated compositions, prepared according to claim 1, characterized in that it is composed of one or more ozonized natural and / or synthetic raw materials that are found in all their varieties and / or in their different states and / or their derivatives. 20. Ozonated compositions, prepared according to claim 1, characterized in that the raw materials can be of natural origin, of synthetic origin or the combination of both; and that they are in all their varieties and / or in their different states and / or their derivatives, 21. Ozonated compositions, prepared according to claim 1, characterized in that the raw materials can be based on raw materials of vegetable origin in all its varieties and / or its derivatives and / or states and / or extracts and / or oils. 22. Ozonated compositions, prepared according to claim 1, characterized in that the raw materials can be based on raw materials of animal origin in all varieties of species and / or their derivatives and / or states and / or extracts and / or oils. 23. Ozonated compositions, prepared according to claim 1, characterized in that the raw materials can be based on raw materials of mineral origin in their different states, organic and inorganic and / or all their derivatives. 24. Ozonated compositions prepared according to claim 1, characterized in that the raw materials can be based on oils of natural origin! and / or synthetic that are in their different states and / or their derivatives. 25. Ozonated compositions prepared according to claim 1, characterized in that the raw materials can be based on gels of natural and / or synthetic origin that are in their different states and / or their derivatives. 26. Ozonated compositions prepared according to claim 1, characterized in that they can be presented in different formats and / or states, for example, without this list being exhaustive, in the form of liquids and / or oils and / or creams and / or gels and / or ointments and / or syrups and / or jellies and / or capsules and / or tablets and / or drops and / or suppositories and / or injectables and / or spray and / or sweets, among others; according to the needs of therapeutic application. 27. Ozonated compositions prepared according to claim 1, characterized in that they are bactericidal and / or fungicidal and / or germicidal and / or antiviral in their composition. 28. Ozonated compositions prepared according to claim 1, characterized by having a balanced PH 29. Ozonated compositions made according to claim 1, CHARACTERIZED, because it allows to contain high quality bioactive nutrients, available in its composition. 30. Ozonated compositions made according to claim 1, CHARACTERIZED, because it allows to oxygenate, nourish and hydrate simultaneously the cellular tissue in general. 31. Ozonated compositions made according to claim 1, CHARACTERIZED, because it allows repair and regeneration at the cellular level of the tissue in general. 32. Ozonated compositions prepared according to claim 1, CHARACTERIZED, because it allows having a good tolerance in the application for topical use either for creams and / or gels and / or oils and / or ointments and / or spray formats, among others. 33. Ozonated compositions prepared according to claim 1, CHARACTERIZED, because it allows having a good tolerance in oral intake, either for formats of oils and / or syrups and / or jellies and / or capsules and / or tablets and / or drops , among others. 34. Ozonated compositions made according to claim 1, characterized in that the constitution of the formula of a composition is based on the exhaustive selection of raw materials, whose active ingredients of its composition, are aimed at meeting the nutritional requirements of one or more metabolic functions; satisfying the therapeutic needs of repair and regeneration of cellular tissue in general. 35. Ozonated compositions prepared according to claim 1, characterized in that vacuum packages are used, whose dispenser does not allow air to enter the composition, in the process of extracting the composition, maintaining the composition in vacuum.