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WO2010079253A3 - Biomarqueurs pour le diagnostic de la fibrose - Google Patents

Biomarqueurs pour le diagnostic de la fibrose Download PDF

Info

Publication number
WO2010079253A3
WO2010079253A3 PCT/ES2010/070007 ES2010070007W WO2010079253A3 WO 2010079253 A3 WO2010079253 A3 WO 2010079253A3 ES 2010070007 W ES2010070007 W ES 2010070007W WO 2010079253 A3 WO2010079253 A3 WO 2010079253A3
Authority
WO
WIPO (PCT)
Prior art keywords
markers
bio
fibrosis
methods
diagnosing fibrosis
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/ES2010/070007
Other languages
English (en)
Spanish (es)
Other versions
WO2010079253A2 (fr
Inventor
Fernando José CORRALES IZQUIERDO
Joaquín FERNÁNDEZ IRIGOYEN
Leticia Odriozola Moncayola
Jesús María PRIETO VALTUEÑA
Enrique SANTAMARÍA MARTÍNEZ
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Proyecto de Biomedicina CIMA SL
Original Assignee
Proyecto de Biomedicina CIMA SL
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Proyecto de Biomedicina CIMA SL filed Critical Proyecto de Biomedicina CIMA SL
Publication of WO2010079253A2 publication Critical patent/WO2010079253A2/fr
Publication of WO2010079253A3 publication Critical patent/WO2010079253A3/fr
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/08—Hepato-biliairy disorders other than hepatitis
    • G01N2800/085—Liver diseases, e.g. portal hypertension, fibrosis, cirrhosis, bilirubin

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Immunology (AREA)
  • Biotechnology (AREA)
  • Analytical Chemistry (AREA)
  • Cell Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

L'invention concerne des méthodes pour la détection et le diagnostic de la fibrose et de maladies associées à la fibrose, ainsi que des méthodes destinées à déterminer l'efficacité d'un traitement contre la fibrose sur la base de la détermination des niveaux d'expression de biomarqueurs, ces biomarqueurs étant choisis parmi SLURPI, HAMP, GSN et/ou APOD. L'invention concerne également des trousses comprenant des réactifs appropriés pour la mise en oeuvre desdites méthodes.
PCT/ES2010/070007 2009-01-09 2010-01-07 Biomarqueurs pour le diagnostic de la fibrose Ceased WO2010079253A2 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
ESP200900056 2009-01-09
ES200900056 2009-01-09

Publications (2)

Publication Number Publication Date
WO2010079253A2 WO2010079253A2 (fr) 2010-07-15
WO2010079253A3 true WO2010079253A3 (fr) 2010-10-14

Family

ID=42232658

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/ES2010/070007 Ceased WO2010079253A2 (fr) 2009-01-09 2010-01-07 Biomarqueurs pour le diagnostic de la fibrose

Country Status (1)

Country Link
WO (1) WO2010079253A2 (fr)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2457243T3 (es) 2006-09-08 2014-04-25 The Chancellor, Masters And Scholars Of The University Of Oxford Diagnóstico clínico de una fibrosis hepática utilizando APOL1 de suero humano como biomarcador
ES2527455T3 (es) 2009-05-14 2015-01-23 The Chancellor, Masters And Scholars Of The University Of Oxford Diagnóstico clínico de fibrosis/cirrosis hepática usando biomarcadores de proteínas plasmáticas humanas poco abundantes
GB201614455D0 (en) 2016-08-24 2016-10-05 Univ Oxford Innovation Ltd Biomarkers
CN114527275A (zh) * 2022-02-22 2022-05-24 深圳市亚辉龙生物科技股份有限公司 肝纤维化的诊断试剂盒

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002016949A1 (fr) * 2000-08-21 2002-02-28 Assistance Publique - Hopitaux De Paris Diagnostic de maladie fibrogene a l'aide de marqueurs biochimiques
WO2003073822A2 (fr) * 2002-02-28 2003-09-12 Prometheus Laboratories, Inc. Procedes de diagnostic de fibrose hepatique
WO2008123948A1 (fr) * 2007-03-27 2008-10-16 Vermillion, Inc. Biomarqueurs pour cancer des ovaires

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2236186B (en) 1989-08-22 1994-01-05 Finnigan Mat Gmbh Process and device for laser desorption of analyte molecular ions, especially of biomolecules
US5045694A (en) 1989-09-27 1991-09-03 The Rockefeller University Instrument and method for the laser desorption of ions in mass spectrometry
NZ267842A (en) 1993-05-28 1997-09-22 Baylor College Medicine Apparatus for measuring molecular mass (by mass spectrometry) in which the sample is ionised on the sample holder and desorbed therefrom by laser pulses
NZ516848A (en) 1997-06-20 2004-03-26 Ciphergen Biosystems Inc Retentate chromatography apparatus with applications in biology and medicine
KR20030031911A (ko) 2001-04-19 2003-04-23 싸이퍼젠 바이오시스템즈, 인코포레이티드 질량 분석법과 친화성 태그를 이용한 생물분자 특성화
JP2005500543A (ja) 2001-08-13 2005-01-06 ビヨンド ジェノミクス， インコーポレイテッド 生物学的系をプロファイリングするための方法およびシステム
US20030199001A1 (en) 2002-04-23 2003-10-23 Pitt Aldo M. Sample preparation of biological fluids for proteomic applications
FR2870348B1 (fr) 2004-05-14 2010-08-27 Univ Angers Methode pour diagnostiquer la presence et/ou la severite d'une pathologie hepathique chez un sujet
ES2288358B1 (es) 2005-07-01 2008-11-16 Proyecto De Biomedicina Cima, S.L. Marcadores de fibrosis.
TW200745556A (en) 2006-01-24 2007-12-16 Ind Tech Res Inst Biomarkers for liver fibrotic injury
ES2457243T3 (es) 2006-09-08 2014-04-25 The Chancellor, Masters And Scholars Of The University Of Oxford Diagnóstico clínico de una fibrosis hepática utilizando APOL1 de suero humano como biomarcador

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002016949A1 (fr) * 2000-08-21 2002-02-28 Assistance Publique - Hopitaux De Paris Diagnostic de maladie fibrogene a l'aide de marqueurs biochimiques
WO2003073822A2 (fr) * 2002-02-28 2003-09-12 Prometheus Laboratories, Inc. Procedes de diagnostic de fibrose hepatique
WO2008123948A1 (fr) * 2007-03-27 2008-10-16 Vermillion, Inc. Biomarqueurs pour cancer des ovaires

Also Published As

Publication number Publication date
WO2010079253A2 (fr) 2010-07-15

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