[go: up one dir, main page]

WO2010058393A3 - Compositions and methods for the prognosis of colon cancer - Google Patents

Compositions and methods for the prognosis of colon cancer Download PDF

Info

Publication number
WO2010058393A3
WO2010058393A3 PCT/IL2009/001075 IL2009001075W WO2010058393A3 WO 2010058393 A3 WO2010058393 A3 WO 2010058393A3 IL 2009001075 W IL2009001075 W IL 2009001075W WO 2010058393 A3 WO2010058393 A3 WO 2010058393A3
Authority
WO
WIPO (PCT)
Prior art keywords
prognosis
compositions
colon cancer
methods
derived
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/IL2009/001075
Other languages
French (fr)
Other versions
WO2010058393A2 (en
Inventor
Gila Lithwick Yanai
Baruch Brenner
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Mor Research Applications Ltd
Rosetta Genomics Ltd
Original Assignee
Mor Research Applications Ltd
Rosetta Genomics Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mor Research Applications Ltd, Rosetta Genomics Ltd filed Critical Mor Research Applications Ltd
Publication of WO2010058393A2 publication Critical patent/WO2010058393A2/en
Publication of WO2010058393A3 publication Critical patent/WO2010058393A3/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/112—Disease subtyping, staging or classification
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/118—Prognosis of disease development
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/178—Oligonucleotides characterized by their use miRNA, siRNA or ncRNA

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Analytical Chemistry (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Hospice & Palliative Care (AREA)
  • Biophysics (AREA)
  • Oncology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Described herein are compositions and methods for prognosis of colon cancer. The compositions are microRNA molecules associated with the prognosis of colon cancer, as well as various nucleic acid molecules relating thereto or derived thereof.
PCT/IL2009/001075 2008-11-20 2009-11-15 Compositions and methods for the prognosis of colon cancer Ceased WO2010058393A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US11630108P 2008-11-20 2008-11-20
US61/116,301 2008-11-20

Publications (2)

Publication Number Publication Date
WO2010058393A2 WO2010058393A2 (en) 2010-05-27
WO2010058393A3 true WO2010058393A3 (en) 2010-08-12

Family

ID=42198596

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IL2009/001075 Ceased WO2010058393A2 (en) 2008-11-20 2009-11-15 Compositions and methods for the prognosis of colon cancer

Country Status (1)

Country Link
WO (1) WO2010058393A2 (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5946466B2 (en) * 2010-12-01 2016-07-06 アンスティチュ ナショナル ドゥ ラ サンテ エ ドゥ ラ ルシェルシュ メディカル Method for predicting colorectal cancer outcome by analyzing miRNA expression
JP5836397B2 (en) * 2011-01-13 2015-12-24 インダストリアル テクノロジー リサーチ インスティテュートＩｎｄｕｓｔｒｉａｌ Ｔｅｃｈｎｏｌｏｇｙ Ｒｅｓｅａｒｃｈ Ｉｎｓｔｉｔｕｔｅ Biomarkers for predicting recurrence of colorectal cancer
WO2012160551A2 (en) * 2011-05-24 2012-11-29 Rosetta Genomics Ltd Methods and compositions for determining heart failure or a risk of heart failure
US20150292023A1 (en) * 2011-12-01 2015-10-15 Ohio State Innovation Foundation Materials and Methods Related to NSAID Chemoprevention in Colorectal Cancer

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2007081740A2 (en) * 2006-01-05 2007-07-19 The Ohio State University Research Foundation Micrornarna-based methods and compositions for the diagnosis and treatment of solid cancers
WO2008029295A2 (en) * 2006-06-30 2008-03-13 Rosetta Genomics Ltd A method for detecting nucleic acids

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2007081740A2 (en) * 2006-01-05 2007-07-19 The Ohio State University Research Foundation Micrornarna-based methods and compositions for the diagnosis and treatment of solid cancers
WO2008029295A2 (en) * 2006-06-30 2008-03-13 Rosetta Genomics Ltd A method for detecting nucleic acids

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
MYERS.: "Types of Colon Cancer.", ABOUT.COM, 17 October 2007 (2007-10-17), Retrieved from the Internet <URL:http://web.archive.org/web/20071017140923/http://coloncancer.about.com/od/typesofcancer/alTypeColonCancer.htm> [retrieved on 20100512] *
VOLINIA ET AL.: "A microRNA expression signature of human solid tumors defines cancer gene targets.", PROC NAT ACAD SCI, vol. 103, no. 7, 14 February 2006 (2006-02-14), pages 2257 - 2261 *

Also Published As

Publication number Publication date
WO2010058393A2 (en) 2010-05-27

Similar Documents

Publication Publication Date Title
WO2010018563A3 (en) Compositions and methods for the prognosis of lymphoma
WO2009111643A3 (en) Microrna markers for recurrence of colorectal cancer
AU2016204376A1 (en) MicroRNA-based methods and compositions for the diagnosis and treatment of ovarian cancer
WO2010099161A8 (en) Micrornas in never-smokers and related materials and methods
WO2009108860A3 (en) Microrna-based methods and compositions for the diagnosis, pronosis and treatment of prostate related disorders
WO2009153775A3 (en) Methods for distinguishing between specific types of lung cancers
WO2009108866A3 (en) Microrna signatures associated with cytogenetics and prognosis in acute myeloid leukemia (aml) and uses thereof
WO2014028429A3 (en) Enzymes and polymerases for the synthesis of rna
WO2009108217A3 (en) Compositions comprising k-ras sirna and methods of use
WO2010127304A3 (en) Sequencing methods
WO2009039189A3 (en) Compositions comprising stat3 sirna and methods of use thereof
WO2008036765A3 (en) Micrornas differentially expressed in pancreatic diseases and uses thereof
WO2007139723A8 (en) Chemicallymodified oligonucleotide primers for nucleic acid amplification
WO2009061381A3 (en) Alpha-amylase variants with altered properties
WO2008067423A3 (en) Methods of improving the introduction of dna into bacterial cells
WO2012068400A3 (en) Mirnas as biomarkers for distinguishing benign from malignant thyroid neoplasms
WO2009012263A3 (en) Tissue-specific micrornas and compositions and uses thereof
WO2007148235A3 (en) Cancer-related nucleic acids
WO2009108918A3 (en) Methods and systems for social networking based on nucleic acid sequences
WO2009037473A3 (en) Nucleobase characterisation
WO2010077740A3 (en) Novel antiviral compounds, compositions, and methods of use
WO2009124255A3 (en) Methods for transcript analysis
WO2009153774A3 (en) Compositions and methods for prognosis of ovarian cancer
WO2009111586A3 (en) Autonomous in vitro evolution
WO2009120712A3 (en) Compositions and methods for diagnosing and treating melanoma

Legal Events

Date Code Title Description
121 Ep: the epo has been informed by wipo that ep was designated in this application

Ref document number: 09827261

Country of ref document: EP

Kind code of ref document: A2

NENP Non-entry into the national phase

Ref country code: DE

122 Ep: pct application non-entry in european phase

Ref document number: 09827261

Country of ref document: EP

Kind code of ref document: A2