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WO2010043950A3 - Propafenone extended release composition - Google Patents

Propafenone extended release composition Download PDF

Info

Publication number
WO2010043950A3
WO2010043950A3 PCT/IB2009/007126 IB2009007126W WO2010043950A3 WO 2010043950 A3 WO2010043950 A3 WO 2010043950A3 IB 2009007126 W IB2009007126 W IB 2009007126W WO 2010043950 A3 WO2010043950 A3 WO 2010043950A3
Authority
WO
WIPO (PCT)
Prior art keywords
propafenone
extended release
release composition
release
rythmol
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/IB2009/007126
Other languages
French (fr)
Other versions
WO2010043950A2 (en
Inventor
Pavithra Anand
Balaji Sathurappan
Anand Sankaranarayanan
Durga Surya Prasad Chelamkuri
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
AIZANT DRUG RESEARCH SOLUTIONS PRIVATE Ltd
Original Assignee
AIZANT DRUG RESEARCH SOLUTIONS PRIVATE Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by AIZANT DRUG RESEARCH SOLUTIONS PRIVATE Ltd filed Critical AIZANT DRUG RESEARCH SOLUTIONS PRIVATE Ltd
Publication of WO2010043950A2 publication Critical patent/WO2010043950A2/en
Publication of WO2010043950A3 publication Critical patent/WO2010043950A3/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/138—Aryloxyalkylamines, e.g. propranolol, tamoxifen, phenoxybenzamine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)

Abstract

An extended release propafenone mini tablets composition with in vitro release profile similar to that of Rythmol SR capsules without using any release retarding excipient wherein thee concentration of propafenone is less than or equal to 80%w/w.
PCT/IB2009/007126 2008-10-15 2009-10-14 Propafenone extended release composition Ceased WO2010043950A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IN2507/CHE/2008 2008-10-15
IN2507CH2008 2008-10-15

Publications (2)

Publication Number Publication Date
WO2010043950A2 WO2010043950A2 (en) 2010-04-22
WO2010043950A3 true WO2010043950A3 (en) 2010-12-02

Family

ID=41561456

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IB2009/007126 Ceased WO2010043950A2 (en) 2008-10-15 2009-10-14 Propafenone extended release composition

Country Status (1)

Country Link
WO (1) WO2010043950A2 (en)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11278398B2 (en) 2003-12-23 2022-03-22 Boston Scientific Scimed, Inc. Methods and apparatus for endovascular heart valve replacement comprising tissue grasping elements
DE102005003632A1 (en) 2005-01-20 2006-08-17 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Catheter for the transvascular implantation of heart valve prostheses
US7896915B2 (en) 2007-04-13 2011-03-01 Jenavalve Technology, Inc. Medical device for treating a heart valve insufficiency
BR112012021347A2 (en) 2008-02-26 2019-09-24 Jenavalve Tecnology Inc stent for positioning and anchoring a valve prosthesis at an implantation site in a patient's heart
US9044318B2 (en) 2008-02-26 2015-06-02 Jenavalve Technology Gmbh Stent for the positioning and anchoring of a valvular prosthesis
US10856978B2 (en) 2010-05-20 2020-12-08 Jenavalve Technology, Inc. Catheter system
CN103002833B (en) 2010-05-25 2016-05-11 耶拿阀门科技公司 Artificial heart valve and comprise artificial heart valve and support through conduit carry interior prosthese
WO2011154012A1 (en) * 2010-06-10 2011-12-15 Lifecycle Pharma A/S Mini-tablets comprising porous adsorbent material
EP3038567B1 (en) 2013-08-30 2022-09-07 JenaValve Technology, Inc. Radially collapsible frame for a prosthetic valve and method for manufacturing such a frame
CN103432094A (en) * 2013-09-11 2013-12-11 中国药科大学 Propafenone hydrochloride sustained-release preparation and preparation method thereof
EP4353203A3 (en) 2015-03-20 2024-07-03 JenaValve Technology, Inc. Heart valve prosthesis delivery system
JP6767388B2 (en) 2015-05-01 2020-10-14 イェーナヴァルヴ テクノロジー インコーポレイテッド Devices and methods to reduce the proportion of pacemakers in heart valve replacement
CN105213349A (en) * 2015-10-10 2016-01-06 赛乐医药科技(上海)有限公司 A kind of propafenone hydrochloride sustained-release micro-pill capsules agent and its preparation method and application
EP3454795B1 (en) 2016-05-13 2023-01-11 JenaValve Technology, Inc. Heart valve prosthesis delivery system for delivery of heart valve prosthesis with introducer sheath and loading system
CN105902984A (en) * 2016-05-29 2016-08-31 山东仁和堂药业有限公司 Propafenone hydrochloride tablets and preparation method thereof
CN110392557A (en) 2017-01-27 2019-10-29 耶拿阀门科技股份有限公司 Heart valve simulation
CN109394722B (en) * 2018-12-26 2020-06-12 上海宣泰医药科技有限公司 Propafenone micro-tablet, multi-unit dosage form containing same, preparation method and application thereof
EP4615369A1 (en) 2022-11-09 2025-09-17 JenaValve Technology, Inc. Catheter system for sequential deployment of an expandable implant
CN117462502B (en) * 2023-10-26 2024-06-11 山东丰金生物医药有限公司 Propafenone hydrochloride sustained-release composition and preparation method thereof
CN119235802A (en) * 2024-09-29 2025-01-03 江苏神龙药业有限公司 A production and processing technology of propafenone hydrochloride tablets

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4797287A (en) * 1984-06-19 1989-01-10 Basf Aktiengesellschaft Cylindrical microtablets
US5681588A (en) * 1993-04-03 1997-10-28 Knoll Aktiengesellschaft Delayed release microtablet of β-phenylpropiophenone derivatives
US20050271718A1 (en) * 2004-06-07 2005-12-08 Sherman Bernard C Sustained release propafenone hydrochloride capsules
BG108784A (en) * 2004-07-02 2006-02-28 "Софарма" Ад Medicamentous form of propaphenone and process for the preparation thereof
US20080014257A1 (en) * 2006-07-14 2008-01-17 Par Pharmaceutical, Inc. Oral dosage forms

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2469327A1 (en) 2004-06-07 2005-12-07 Bernard Charles Sherman Propafenone hydrochloride capsules containing microtablets
US20110091566A1 (en) 2007-09-25 2011-04-21 Nirmal Mulye Controlled release pharmaceutical compositions

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4797287A (en) * 1984-06-19 1989-01-10 Basf Aktiengesellschaft Cylindrical microtablets
US5681588A (en) * 1993-04-03 1997-10-28 Knoll Aktiengesellschaft Delayed release microtablet of β-phenylpropiophenone derivatives
US20050271718A1 (en) * 2004-06-07 2005-12-08 Sherman Bernard C Sustained release propafenone hydrochloride capsules
BG108784A (en) * 2004-07-02 2006-02-28 "Софарма" Ад Medicamentous form of propaphenone and process for the preparation thereof
US20080014257A1 (en) * 2006-07-14 2008-01-17 Par Pharmaceutical, Inc. Oral dosage forms

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
DATABASE CA [online] CHEMICAL ABSTRACTS SERVICE, COLUMBUS, OHIO, US; 20 September 2007 (2007-09-20), XP002604025, retrieved from STN Database accession no. 147:308278 *
S. MITCHELL ET AL.: "A framework to investigate drug release variability arising from hypromellose viscosity specifications in controlled release matrix tablets", JOURNAL OF PHARMACEUTICAL SCIENCES, vol. 97, no. 6, June 2008 (2008-06-01), pages 2277 - 2285, XP002604026 *

Also Published As

Publication number Publication date
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