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WO2010043408A3 - Fésotérodine microencapsulée - Google Patents

Fésotérodine microencapsulée Download PDF

Info

Publication number
WO2010043408A3
WO2010043408A3 PCT/EP2009/007445 EP2009007445W WO2010043408A3 WO 2010043408 A3 WO2010043408 A3 WO 2010043408A3 EP 2009007445 W EP2009007445 W EP 2009007445W WO 2010043408 A3 WO2010043408 A3 WO 2010043408A3
Authority
WO
WIPO (PCT)
Prior art keywords
fesoterodine
microencapsulated
relates
pharmaceutical
active ingredient
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/EP2009/007445
Other languages
German (de)
English (en)
Other versions
WO2010043408A2 (fr
Inventor
Katrin Rimkus
Frank Muskulus
Sandra Brueck
Jana Paetz
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ratiopharm GmbH
Original Assignee
Ratiopharm GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ratiopharm GmbH filed Critical Ratiopharm GmbH
Publication of WO2010043408A2 publication Critical patent/WO2010043408A2/fr
Publication of WO2010043408A3 publication Critical patent/WO2010043408A3/fr
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5036—Polysaccharides, e.g. gums, alginate; Cyclodextrin
    • A61K9/5042—Cellulose; Cellulose derivatives, e.g. phthalate or acetate succinate esters of hydroxypropyl methylcellulose
    • A61K9/5047—Cellulose ethers containing no ester groups, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
    • A61K9/2081—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets with microcapsules or coated microparticles according to A61K9/50
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/10—Drugs for disorders of the urinary system of the bladder
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating

Landscapes

  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Urology & Nephrology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

L'invention concerne de la fésotérodine microencapsulée. L'invention concerne en particulier un intermédiaire pharmaceutique composé d'un noyau (a) et d'une enveloppe (b), (a) le noyau contenant de la fésotérodine et/ou des métabolites comme principe actif et (b) l'enveloppe contenant un ou plusieurs excipients pharmaceutiques qui modifient la libération du principe actif, ainsi qu'un procédé de production de cet intermédiaire. L'invention concerne en outre une composition pharmaceutique contenant l'intermédiaire selon l'invention, en particulier sous forme de comprimés.
PCT/EP2009/007445 2008-10-17 2009-10-16 Fésotérodine microencapsulée Ceased WO2010043408A2 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP08018241 2008-10-17
EP08018241.3 2008-10-17

Publications (2)

Publication Number Publication Date
WO2010043408A2 WO2010043408A2 (fr) 2010-04-22
WO2010043408A3 true WO2010043408A3 (fr) 2010-07-01

Family

ID=40260837

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2009/007445 Ceased WO2010043408A2 (fr) 2008-10-17 2009-10-16 Fésotérodine microencapsulée

Country Status (1)

Country Link
WO (1) WO2010043408A2 (fr)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2549985A1 (fr) * 2010-03-22 2013-01-30 Cadila Healthcare Limited Compositions pharmaceutiques stables comprenant de la fésotérodine
TWI520732B (zh) * 2011-01-18 2016-02-11 輝瑞有限公司 固體分子分散液
EP2508173A1 (fr) 2011-04-08 2012-10-10 LEK Pharmaceuticals d.d. Composition pharmaceutique stable comportant de la fésotérodine
EP2508175A1 (fr) 2011-04-08 2012-10-10 LEK Pharmaceuticals d.d. Composition pharmaceutique contenant de la fésotérodine ou un sel ou un solvate de celle-ci
WO2013054337A1 (fr) * 2011-07-04 2013-04-18 Cadila Healthcare Limited Compositions pharmaceutiques à libération prolongée de fésotérodine
WO2013160909A1 (fr) * 2012-03-19 2013-10-31 Astron Research Limited Composition stable de fésotérodine
CZ2014400A3 (cs) 2014-06-09 2015-12-16 Zentiva, K.S. Stabilizovaná formulace fesoterodinu
TR201721437A2 (tr) 2017-12-25 2019-07-22 Sanovel Ilac Sanayi Ve Ticaret Anonim Sirketi Fesoterodi̇ni̇n modi̇fi̇ye salim sağlayan formülasyonlari
WO2019132832A1 (fr) 2017-12-25 2019-07-04 Sanovel Ilac Sanayi Ve Ticaret Anonim Sirketi Compositions de comprimés de fumarate de fésotérodine
CN110151720B (zh) * 2019-05-09 2019-12-17 合肥信风科技开发有限公司 含非索罗定的药用组合物及其制备方法

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2008006506A1 (fr) * 2006-07-10 2008-01-17 Dr. R. Pfleger Chemische Fabrik Gmbh Préparation pharmaceutique pour administration par voie orale avec libération contrôlée de substances actives dans l'intestin grêle et son procédé de fabrication

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2008006506A1 (fr) * 2006-07-10 2008-01-17 Dr. R. Pfleger Chemische Fabrik Gmbh Préparation pharmaceutique pour administration par voie orale avec libération contrôlée de substances actives dans l'intestin grêle et son procédé de fabrication

Also Published As

Publication number Publication date
WO2010043408A2 (fr) 2010-04-22

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