[go: up one dir, main page]

WO2009125992A3 - 트랜스포존을 이용한 형질전환용 벡터, 상기 벡터로 형질전환된 미생물 및 이를 이용한 l-라이신 생산방법 - Google Patents

트랜스포존을 이용한 형질전환용 벡터, 상기 벡터로 형질전환된 미생물 및 이를 이용한 l-라이신 생산방법 Download PDF

Info

Publication number
WO2009125992A3
WO2009125992A3 PCT/KR2009/001845 KR2009001845W WO2009125992A3 WO 2009125992 A3 WO2009125992 A3 WO 2009125992A3 KR 2009001845 W KR2009001845 W KR 2009001845W WO 2009125992 A3 WO2009125992 A3 WO 2009125992A3
Authority
WO
WIPO (PCT)
Prior art keywords
vector
lysine
transformation
producing
transposons
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/KR2009/001845
Other languages
English (en)
French (fr)
Other versions
WO2009125992A2 (ko
Inventor
장재우
임상조
최종수
김철하
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
CJ CheilJedang Corp
Original Assignee
CJ CheilJedang Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by CJ CheilJedang Corp filed Critical CJ CheilJedang Corp
Priority to US12/867,649 priority Critical patent/US8323933B2/en
Priority to CN200980107004.7A priority patent/CN102027119B/zh
Priority to JP2010547576A priority patent/JP5412446B2/ja
Priority to BRPI0908450-9A priority patent/BRPI0908450A2/pt
Priority to DE112009000453T priority patent/DE112009000453T5/de
Publication of WO2009125992A2 publication Critical patent/WO2009125992A2/ko
Publication of WO2009125992A3 publication Critical patent/WO2009125992A3/ko
Anticipated expiration legal-status Critical
Priority to US13/683,096 priority patent/US8932861B2/en
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/64—General methods for preparing the vector, for introducing it into the cell or for selecting the vector-containing host
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C12P13/08—Lysine; Diaminopimelic acid; Threonine; Valine

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Cell Biology (AREA)
  • Physics & Mathematics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Plant Pathology (AREA)
  • Medicinal Chemistry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

본 발명은 트랜스포존 유전자를 이용한 형질전환용 벡터, 상기 벡터를 이용하여 형질전환된 미생물 및 상기 미생물을 이용하여 라이신을 생산하는 방법에 관한 것이다.
PCT/KR2009/001845 2008-04-10 2009-04-10 트랜스포존을 이용한 형질전환용 벡터, 상기 벡터로 형질전환된 미생물 및 이를 이용한 l-라이신 생산방법 Ceased WO2009125992A2 (ko)

Priority Applications (6)

Application Number Priority Date Filing Date Title
US12/867,649 US8323933B2 (en) 2008-04-10 2009-04-10 Vector for transformation using transposons, microorganisms transformed by the vector, and method for producing L-lysine using the same
CN200980107004.7A CN102027119B (zh) 2008-04-10 2009-04-10 使用转座子的用于转化的载体、通过该载体转化的微生物及用其生产l-赖氨酸的方法
JP2010547576A JP5412446B2 (ja) 2008-04-10 2009-04-10 トランスポゾンを利用した形質転換用ベクター、前記ベクターで形質転換された微生物及びこれを利用したｌ−リジン生産方法
BRPI0908450-9A BRPI0908450A2 (pt) 2008-04-10 2009-04-10 Vetor para transformação usando transposons, micro-organismos transformados pelo vetor e método para produzir l-lisina usando o mesmo
DE112009000453T DE112009000453T5 (de) 2008-04-10 2009-04-10 Vektor zur Transformation unter Verwendung von Transposons, durch den Vektor transformierte Mikroorganismen und Verfahren zum Herstellen von L-Lysin unter Verwendung derselben
US13/683,096 US8932861B2 (en) 2008-04-10 2012-11-21 Transformation vector comprising transposon, microorganisms transformed with the vector, and method for producing L-lysine using the microorganism

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
KR10-2008-0033054 2008-04-10
KR1020080033054A KR101126041B1 (ko) 2008-04-10 2008-04-10 트랜스포존을 이용한 형질전환용 벡터, 상기 벡터로형질전환된 미생물 및 이를 이용한 ｌ-라이신 생산방법

Related Child Applications (2)

Application Number Title Priority Date Filing Date
US12/867,649 A-371-Of-International US8323933B2 (en) 2008-04-10 2009-04-10 Vector for transformation using transposons, microorganisms transformed by the vector, and method for producing L-lysine using the same
US13/683,096 Continuation-In-Part US8932861B2 (en) 2008-04-10 2012-11-21 Transformation vector comprising transposon, microorganisms transformed with the vector, and method for producing L-lysine using the microorganism

Publications (2)

Publication Number Publication Date
WO2009125992A2 WO2009125992A2 (ko) 2009-10-15
WO2009125992A3 true WO2009125992A3 (ko) 2010-01-21

Family

ID=41162404

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/KR2009/001845 Ceased WO2009125992A2 (ko) 2008-04-10 2009-04-10 트랜스포존을 이용한 형질전환용 벡터, 상기 벡터로 형질전환된 미생물 및 이를 이용한 l-라이신 생산방법

Country Status (7)

Country Link
US (1) US8323933B2 (ko)
JP (1) JP5412446B2 (ko)
KR (1) KR101126041B1 (ko)
CN (1) CN102027119B (ko)
BR (1) BRPI0908450A2 (ko)
DE (1) DE112009000453T5 (ko)
WO (1) WO2009125992A2 (ko)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100838038B1 (ko) * 2006-12-29 2008-06-12 씨제이제일제당 (주) Ｌ-라이신 생산능이 향상된 코리네박테리움 속 미생물 및그를 이용한 ｌ-라이신 생산 방법
KR100838035B1 (ko) * 2006-12-29 2008-06-12 씨제이제일제당 (주) Ｌ-라이신 생산능이 향상된 코리네박테리움 속 미생물 및그를 이용한 ｌ-라이신 생산 방법
KR100830826B1 (ko) * 2007-01-24 2008-05-19 씨제이제일제당 (주) 코리네박테리아를 이용하여 글리세롤을 포함한탄소원으로부터 발효산물을 생산하는 방법
US8932861B2 (en) * 2008-04-10 2015-01-13 Cj Cheiljedang Corporation Transformation vector comprising transposon, microorganisms transformed with the vector, and method for producing L-lysine using the microorganism
KR101294935B1 (ko) * 2011-04-01 2013-08-08 씨제이제일제당 (주) 에세리키아 속 균주에서 유래된 프락토키나제 유전자가 도입된 코리네박테리움 속 균주 및 상기 균주를 이용하여 ｌ-아미노산을 생산하는 방법
RU2584593C2 (ru) 2012-01-10 2016-05-20 СиДжей ЧеилДжеданг Корпорейшн МИКРООРГАНИЗМЫ Corynebacterium, СПОСОБНЫЕ УТИЛИЗИРОВАТЬ КСИЛОЗУ, И СПОСОБ ПОЛУЧЕНИЯ L-ЛИЗИНА С ПРИМЕНЕНИЕМ ТАКИХ МИКРООРГАНИЗМОВ
KR101498630B1 (ko) * 2013-10-28 2015-03-04 씨제이제일제당 주식회사 Ｌ-라이신 생산능이 향상된 코리네박테리움 속 미생물 및 이를 이용한 l-라이신 생산방법
KR101601404B1 (ko) 2014-04-09 2016-03-09 씨제이제일제당 (주) Ｌ-라이신 생산능을 갖는 미생물 및 이를 이용한 ｌ-라이신 생산 방법
AU2015250514B2 (en) 2014-04-25 2018-05-17 Cj Cheiljedang Corporation Microorganisms for Producing Diamine and Process for Producing Diamine Using Them
KR101732788B1 (ko) 2014-04-25 2017-05-10 씨제이제일제당 (주) 다이아민 생산 미생물 및 이를 이용한 다이아민 생산방법
KR101813759B1 (ko) 2015-06-24 2018-01-02 씨제이제일제당 (주) 퓨트레신 또는 오르니틴 생산 미생물 및 이를 이용한 퓨트레신 또는 오르니틴 생산방법
KR101735935B1 (ko) 2015-07-20 2017-05-16 씨제이제일제당 (주) 퓨트레신 또는 오르니틴 생산 미생물 및 이를 이용한 퓨트레신 또는 오르니틴 생산방법
KR102011394B1 (ko) 2017-07-19 2019-10-22 씨제이제일제당 주식회사 퓨트레신을 생산하는 미생물 및 이를 이용한 퓨트레신 생산방법
KR102003911B1 (ko) 2018-02-23 2019-07-25 씨제이제일제당 주식회사 마이코스포린 유사 아미노산을 생산하는 미생물 및 이를 이용한 마이코스포린 유사 아미노산의 생산방법
KR101968317B1 (ko) 2018-02-23 2019-04-11 씨제이제일제당 주식회사 신규 l-트립토판 배출 단백질 및 이를 이용한 l-트립토판을 생산하는 방법
KR102175112B1 (ko) 2019-04-22 2020-11-06 씨제이제일제당 주식회사 L-쓰레오닌 생산능이 강화된 미생물 및 이를 이용한 쓰레오닌 생산방법
KR102183209B1 (ko) 2019-09-09 2020-11-26 씨제이제일제당 주식회사 L-쓰레오닌 배출 단백질의 변이체 및 이를 이용한 l-쓰레오닌 생산 방법
KR102246288B1 (ko) 2020-08-13 2021-04-29 씨제이제일제당 주식회사 퓨트레신 생산 미생물 및 이를 이용한 퓨트레신 생산방법
KR102617168B1 (ko) 2020-12-09 2023-12-21 씨제이제일제당 (주) 쉬와넬라 오네이덴시스 유래 단백질을 발현하는 미생물, 및 이를 이용한 l-아미노산 생산 방법
KR102616694B1 (ko) 2020-12-09 2023-12-20 씨제이제일제당 (주) 쉬와넬라 아틀란티카 유래 단백질을 발현하는 미생물, 및 이를 이용한 l-아미노산 생산 방법
WO2022191357A1 (ko) * 2021-03-09 2022-09-15 대상 주식회사 L-라이신 생산능이 향상된 코리네박테리움 글루타미쿰 변이주 및 이를 이용한 l-라이신의 생산 방법
KR20240113674A (ko) 2023-01-13 2024-07-23 씨제이제일제당 (주) 신규 카르노신 합성 효소 및 이를 이용한 카르노신 생산 방법

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6746855B2 (en) * 1999-07-07 2004-06-08 Dégussa-Hüls Aktiengesellschaft L-lysine-producing corynebacteria and process for the preparation of L-lysine
KR20080025355A (ko) * 2006-09-15 2008-03-20 씨제이제일제당 (주) Ｌ－라이신 생산능이 향상된 코리네박테리아 및 그를이용한 ｌ－라이신 생산 방법

Family Cites Families (40)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH06102028B2 (ja) 1985-10-04 1994-12-14 協和醗酵工業株式会社 アミノ酸の製造法
FR2665711B1 (fr) 1990-08-08 1993-08-13 Centre Nat Rech Scient Integron de corynebacterie, procede de transformation d'une corynebacterie par ledit integron et corynebacterie obtenue.
DE4208785A1 (de) 1992-03-19 1993-09-23 Degussa Verfahren zum auffinden von insertionselementen (is-elemente) oder transposonen
FR2702492B1 (fr) 1993-03-12 1995-05-24 Rhone Poulenc Chimie Procédé de production par fermentation d'acide itaconique.
JPH07121228A (ja) 1993-10-22 1995-05-12 Mazda Motor Corp 生産設備の生産情報確認方法
JPH07155184A (ja) 1993-12-08 1995-06-20 Ajinomoto Co Inc 発酵法によるｌ−リジンの製造法
JPH0970291A (ja) 1995-06-30 1997-03-18 Ajinomoto Co Inc 人工トランスポゾンを用いた遺伝子増幅方法
EP0756007A3 (en) 1995-06-30 1997-10-29 Ajinomoto Kk Gene-marking process with artificial transposon
SK285201B6 (sk) 1996-12-05 2006-08-03 Ajinomoto Co., Inc. Rekombinantná DNA, autonómne reprodukovaná v bunkách koryneformnej baktérie, koryneformná baktéria a spôsob výroby L-lyzínu, vektor pVK7
JP4075087B2 (ja) 1996-12-05 2008-04-16 味の素株式会社 Ｌ−リジンの製造法
JP4168463B2 (ja) 1996-12-05 2008-10-22 味の素株式会社 Ｌ−リジンの製造法
CA2305577A1 (en) 1997-10-04 1999-04-15 Forschungszentrum Julich Gmbh Method for microbial production of amino acids of the aspartate and/or glutamate family and agents which can be used in said method
DE19931317A1 (de) * 1999-07-07 2001-01-11 Degussa L-Lysin produzierende coryneforme Bakterien und Verfahren zur Herstellung von L-Lysin
BR9816106A (pt) 1998-12-23 2001-09-11 Massachusetts Inst Technology Carboxilase de piruvato de corynebacterium glutamicum
KR100313134B1 (ko) 1999-06-18 2001-11-05 윤덕용 글리세롤을 이용한 숙신산의 생산방법
US20030049804A1 (en) 1999-06-25 2003-03-13 Markus Pompejus Corynebacterium glutamicum genes encoding metabolic pathway proteins
US20050153402A1 (en) 1999-06-25 2005-07-14 Basf Ag Corynebacterium glutamicum genes encoding regulatory proteins
DE19931314A1 (de) 1999-07-07 2001-01-11 Degussa L-Lysin produzierende coryneforme Bakterien und Verfahren zur Herstellung von Lysin
US6861246B2 (en) 1999-07-07 2005-03-01 Degussa Ag L-lysine-producing corynebacteria and process for the preparation of lysine
US6962989B1 (en) 1999-07-08 2005-11-08 Basf Aktiengesellschaft Corynebacterium glutamicum genes encoding novel proteins
DE19941478A1 (de) 1999-09-01 2001-03-08 Degussa Neue für das thrE-Gen codierende Nukleotidsequenzen und Verfahren zur fermentativen Herstellung von L-Threonin mit coryneformen Bakterien
US6872553B2 (en) 1999-10-20 2005-03-29 Degussa Ag Nucleotide sequences which code for the pck gene
JP4623825B2 (ja) 1999-12-16 2011-02-02 協和発酵バイオ株式会社 新規ポリヌクレオチド
US6927046B1 (en) 1999-12-30 2005-08-09 Archer-Daniels-Midland Company Increased lysine production by gene amplification using coryneform bacteria
DE10014546A1 (de) 2000-03-23 2001-09-27 Degussa Für das dapC-Gen kodierende Nukleotidsequenzen und Verfahren zur Herstellung von L-Lysin
KR100397322B1 (ko) 2000-12-30 2003-09-06 씨제이 주식회사 엘-라이신의 제조방법
DE10110760A1 (de) 2001-01-30 2002-08-01 Degussa Neue für das otsA-Gen kodierende Nukleotidsequenzen
EP1358337A1 (en) 2001-01-30 2003-11-05 Degussa AG Nucleotide sequences which code for the otsa gene of c. glutamicum
US7160711B2 (en) 2001-08-06 2007-01-09 Degussa Ag Coryneform bacteria which produce chemical compounds I
US7527966B2 (en) * 2002-06-26 2009-05-05 Transgenrx, Inc. Gene regulation in transgenic animals using a transposon-based vector
US20050255568A1 (en) 2003-05-30 2005-11-17 Bailey Richard B Methods and compositions for amino acid production
BRPI0417706A (pt) 2003-12-18 2007-03-20 Basf Ag métodos para aumentar o fluxo metabólico através da via pentose fosfato em um microorganismo, e para produzir um produto quimico fino, e microorganismo recombinante
KR100564805B1 (ko) 2003-12-23 2006-03-27 씨제이 주식회사 프락토키나제 유전자에 의하여 형질전환된 코리네박테리움종 및 그를 이용한 ｌ-라이신의 제조방법
KR100620092B1 (ko) 2004-12-16 2006-09-08 씨제이 주식회사 코리네박테리움 속 세포로부터 유래된 신규한 프로모터서열, 그를 포함하는 발현 카세트 및 벡터, 상기 벡터를포함하는 숙주 세포 및 그를 이용하여 유전자를 발현하는방법
KR100653742B1 (ko) 2004-12-30 2006-12-05 씨제이 주식회사 신규한 ｌ-라이신-유도성 프로모터
DE102005018835A1 (de) 2005-04-22 2006-11-02 Degussa Ag Verfahren zur Herstellung von L-Aminosäuren unter Verwendung verbesserter Stämme der Familie Enterobacteriaceae
DE102005047596A1 (de) 2005-10-05 2007-04-12 Degussa Ag Verfahren zur fermentativen Herstellung von L-Aminosäuren unter Verwendung coryneformer Bakterien
KR100838035B1 (ko) 2006-12-29 2008-06-12 씨제이제일제당 (주) Ｌ-라이신 생산능이 향상된 코리네박테리움 속 미생물 및그를 이용한 ｌ-라이신 생산 방법
KR100838038B1 (ko) 2006-12-29 2008-06-12 씨제이제일제당 (주) Ｌ-라이신 생산능이 향상된 코리네박테리움 속 미생물 및그를 이용한 ｌ-라이신 생산 방법
KR100830826B1 (ko) 2007-01-24 2008-05-19 씨제이제일제당 (주) 코리네박테리아를 이용하여 글리세롤을 포함한탄소원으로부터 발효산물을 생산하는 방법

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6746855B2 (en) * 1999-07-07 2004-06-08 Dégussa-Hüls Aktiengesellschaft L-lysine-producing corynebacteria and process for the preparation of L-lysine
KR20080025355A (ko) * 2006-09-15 2008-03-20 씨제이제일제당 (주) Ｌ－라이신 생산능이 향상된 코리네박테리아 및 그를이용한 ｌ－라이신 생산 방법

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
MORMANN, S. ET AL.: "Random mutagenesis in Corynebacterium glutamicum ATCC 13032 using an IS6100-based transposon vector identified the last unknown gene in the histidine biosynthesis pathway", BMC GENOMICS, vol. 7, 10 August 2006 (2006-08-10) *
PETERS-WENDISCH, P. ET AL.: "Metabolic Engineering of Corynebacterium glutamicun for L- Serine Production", APPLIED AND ENVIRONMENTAL MICROBIOLOGY, vol. 71, no. 11, November 2005 (2005-11-01), pages 7139 - 7144 *
TSUGE, Y. ET AL.: "A New Insertion Sequence, IS 14999, from Corynebacterium glutamicun", MICROBIOLOGY, vol. 151, 2005, pages 501 - 508 *

Also Published As

Publication number Publication date
US20100330624A1 (en) 2010-12-30
CN102027119A (zh) 2011-04-20
US8323933B2 (en) 2012-12-04
BRPI0908450A2 (pt) 2015-08-18
DE112009000453T5 (de) 2010-12-30
JP2011512155A (ja) 2011-04-21
JP5412446B2 (ja) 2014-02-12
CN102027119B (zh) 2014-03-05
KR101126041B1 (ko) 2012-03-19
KR20090107665A (ko) 2009-10-14
WO2009125992A2 (ko) 2009-10-15

Similar Documents

Publication Publication Date Title
WO2009125992A3 (ko) 트랜스포존을 이용한 형질전환용 벡터, 상기 벡터로 형질전환된 미생물 및 이를 이용한 l-라이신 생산방법
WO2009049274A8 (en) Microorganism engineered to produce isopropanol
NZ626302A (en) Bispecific binding molecules for anti-angiogenesis therapy
WO2010127304A3 (en) Sequencing methods
WO2011046415A3 (ko) 그래핀의 롤투롤 전사 방법, 그에 의한 그래핀 롤, 및 그래핀의 롤투롤 전사 장치
MX301000B (es) Produccion de etanol en microorganismos.
WO2010093182A3 (ko) Ｌ-아미노산 생산용 미생물 및 이를 이용하여 ｌ-아미노산을 생산하는 방법
WO2009081012A3 (fr) Procedes de production d'acide succinique
WO2013015663A3 (ko) 태양광 및 수소를 이용한 이산화탄소의 환원 방법 및 이를 위한 장치
WO2009114438A3 (en) Cyclohexanedimethanamine by direct amination of cyclohexanedimethanol
WO2008085990A3 (en) Systems for genome selection
UA105785C2 (uk) Спосіб очищення ліпопептидів
PL2350104T3 (pl) Sposób wytwarzania 6-chlorodibenzo [d, f] [1,3,2]-dioksafosfepiny
AU2009232967A8 (en) Agrobacterium-mediated method for producing transformed plant
SG10201701701RA (en) Fermentation product containing equol-producing microorganism having maintained equol-producing ability, and method for producing same
LT2236610T (lt) Patobulintas promotorius ir jo panaudojimas l-lizino gamybos būdui
WO2009041473A1 (ja) ６－フルオロ－３－ヒドロキシ－２－ピラジンカルボニトリルの有機アミン塩およびその製造法
WO2010112452A9 (en) Oligocondensed perylene bisimides
MY158910A (en) Surface modified silicic acid semi-gels
IL217656A (en) Method for producing 1,1,3-trichloro-1-propane
WO2011004402A3 (en) Improved process for the preparation of ambrisentan and novel intermediates thereof
EP2405006A4 (en) MICROORGANISM FOR THE MANUFACTURE OF L-AMINO ACIDS AND METHOD FOR THE PRODUCTION OF L-AMINO ACIDS THEREWITH
WO2009076948A3 (de) Reduktone zur erzeugung von biogas
WO2012070891A3 (ko) 심플리실리움 라멜리콜라 ｂｃｐ 균주 배양용 배지 조성물 및 이의 배양방법
GB0916053D0 (en) Process for producing vinegar and vinegar produced by this method

Legal Events

Date Code Title Description
WWE Wipo information: entry into national phase

Ref document number: 200980107004.7

Country of ref document: CN

121 Ep: the epo has been informed by wipo that ep was designated in this application

Ref document number: 09729413

Country of ref document: EP

Kind code of ref document: A2

WWE Wipo information: entry into national phase

Ref document number: 12867649

Country of ref document: US

WWE Wipo information: entry into national phase

Ref document number: 2010547576

Country of ref document: JP

WWE Wipo information: entry into national phase

Ref document number: 1120090004539

Country of ref document: DE

RET De translation (de og part 6b)

Ref document number: 112009000453

Country of ref document: DE

Date of ref document: 20101230

Kind code of ref document: P

122 Ep: pct application non-entry in european phase

Ref document number: 09729413

Country of ref document: EP

Kind code of ref document: A2

ENP Entry into the national phase

Ref document number: PI0908450

Country of ref document: BR

Kind code of ref document: A2

Effective date: 20100831