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WO2009115165A3 - Cooling preparations for contact with human skin and/or mucous membranes, containing (1r,2s,5r)-2-isopropyl-5-methyl-n-(2-(pyridin-2-yl)ethyl-cyclohexane carboxamide and/or (1r,2s,5r)-n-(4-(cyanomethyl)-phenyl)-2-isopropyl-5-methylcyclohexane carboxamide - Google Patents

Cooling preparations for contact with human skin and/or mucous membranes, containing (1r,2s,5r)-2-isopropyl-5-methyl-n-(2-(pyridin-2-yl)ethyl-cyclohexane carboxamide and/or (1r,2s,5r)-n-(4-(cyanomethyl)-phenyl)-2-isopropyl-5-methylcyclohexane carboxamide Download PDF

Info

Publication number
WO2009115165A3
WO2009115165A3 PCT/EP2009/000719 EP2009000719W WO2009115165A3 WO 2009115165 A3 WO2009115165 A3 WO 2009115165A3 EP 2009000719 W EP2009000719 W EP 2009000719W WO 2009115165 A3 WO2009115165 A3 WO 2009115165A3
Authority
WO
WIPO (PCT)
Prior art keywords
isopropyl
carboxamide
cyanomethyl
pyridin
phenyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/EP2009/000719
Other languages
German (de)
French (fr)
Other versions
WO2009115165A2 (en
Inventor
Stefan Biel
Julia Eckert
Björna Windisch
Gitta Neufang
Stefanie Knaupmeier
Stefanie Höltkemeier
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Beiersdorf AG
Original Assignee
Beiersdorf AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Beiersdorf AG filed Critical Beiersdorf AG
Publication of WO2009115165A2 publication Critical patent/WO2009115165A2/en
Publication of WO2009115165A3 publication Critical patent/WO2009115165A3/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
    • A61K8/42—Amides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/275—Nitriles; Isonitriles
    • A61K31/277—Nitriles; Isonitriles having a ring, e.g. verapamil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4402—Non condensed pyridines; Hydrogenated derivatives thereof only substituted in position 2, e.g. pheniramine, bisacodyl
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A61K8/4906—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom
    • A61K8/4926—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with one nitrogen as the only hetero atom having six membered rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/20—Chemical, physico-chemical or functional or structural properties of the composition as a whole
    • A61K2800/24—Thermal properties
    • A61K2800/244—Endothermic; Cooling; Cooling sensation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q15/00—Anti-perspirants or body deodorants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
    • A61Q17/04—Topical preparations for affording protection against sunlight or other radiation; Topical sun tanning preparations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A61Q19/002—Aftershave preparations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A61Q19/004—Aftersun preparations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q5/00—Preparations for care of the hair
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q5/00—Preparations for care of the hair
    • A61Q5/02—Preparations for cleaning the hair

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Dermatology (AREA)
  • Birds (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Cosmetics (AREA)
  • Medicinal Preparation (AREA)
  • Pyridine Compounds (AREA)

Abstract

The invention relates to cooling preparations for contact with human skin and/or mucous membranes, containing (1R,2S,5R)-2-isopropyl-5-methyl-N-(2-(pyridin-2-yl)ethyl-cyclohexane carboxamide and/or (1R,2S,5R)-N-(4-(cyanomethyl)-phenyl)-2-isopropyl-5-methylcyclohexane carboxamide.
PCT/EP2009/000719 2008-03-20 2009-02-04 Cooling preparations for contact with human skin and/or mucous membranes, containing (1r,2s,5r)-2-isopropyl-5-methyl-n-(2-(pyridin-2-yl)ethyl-cyclohexane carboxamide and/or (1r,2s,5r)-n-(4-(cyanomethyl)-phenyl)-2-isopropyl-5-methylcyclohexane carboxamide Ceased WO2009115165A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE102008015428A DE102008015428A1 (en) 2008-03-20 2008-03-20 Cooling preparations for human skin and / or mucosal contact containing (1R, 2S, 5R) -2-isopropyl-5-methyl-N- (2- (pyridin-2-yl) -ethyl-cyclohexanecarboxamide and / or ( 1R, 2S, 5R) -N- (4- (cyanomethyl) phenyl) -2-isopropyl-5-methylcyclohexanecarboxamide
DE102008015428.8 2008-03-20

Publications (2)

Publication Number Publication Date
WO2009115165A2 WO2009115165A2 (en) 2009-09-24
WO2009115165A3 true WO2009115165A3 (en) 2009-11-19

Family

ID=40941962

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2009/000719 Ceased WO2009115165A2 (en) 2008-03-20 2009-02-04 Cooling preparations for contact with human skin and/or mucous membranes, containing (1r,2s,5r)-2-isopropyl-5-methyl-n-(2-(pyridin-2-yl)ethyl-cyclohexane carboxamide and/or (1r,2s,5r)-n-(4-(cyanomethyl)-phenyl)-2-isopropyl-5-methylcyclohexane carboxamide

Country Status (2)

Country Link
DE (1) DE102008015428A1 (en)
WO (1) WO2009115165A2 (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102009032245A1 (en) * 2009-07-06 2011-01-13 Beiersdorf Ag Glycyrrhetinsäure containing cosmetic preparation
DE102009032244A1 (en) * 2009-07-06 2011-01-13 Beiersdorf Ag Glycyrrhetinsäure containing, perfumed cosmetic preparation
DE102019218240A1 (en) * 2019-11-26 2021-05-27 Beiersdorf Ag Active ingredient combinations of ubiquinol and glyceryl stearate citrate and cosmetic or dermatological preparations containing such active ingredient combinations
GB202012170D0 (en) * 2020-08-05 2020-09-16 Givaudan Sa Organic compounds

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4136163A (en) * 1971-02-04 1979-01-23 Wilkinson Sword Limited P-menthane carboxamides having a physiological cooling effect
WO1993023005A1 (en) * 1992-05-18 1993-11-25 The Procter & Gamble Company Coolant compositions
WO2005049553A1 (en) * 2003-11-21 2005-06-02 Givaudan Sa N-substituted p-menthane carbosamided
WO2007019719A1 (en) * 2005-08-15 2007-02-22 Givaudan Sa Cooling compounds

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1006572B (en) * 1972-04-18 1976-10-20 Wilkinson Sword Ltd LOCAL AND OTHER INGESTIBLE COMPOSITIONS HAVING A PHYSIOLOGICAL CO-COOLING EFFECT ON THE SKIN AND MUCOUS MEMBRANES OF THE BODY
GB1422998A (en) * 1973-03-22 1976-01-28 Wilkinson Sword Ltd Cyclohexanecarboxamides having a physiological cooling effect and compositions containing them
FR2789390B3 (en) * 1999-02-10 2001-03-09 Sanofi Sa NOVEL PIPERIDINE DERIVATIVES, PROCESS FOR THEIR PRODUCTION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM
DE10029462A1 (en) 2000-06-21 2002-01-03 Clariant Gmbh New water soluble polymers based on macromonomer with polyalkylene oxide units, useful as adjuvants in cosmetic, pharmaceutical and agrochemical compositions
EP1682079B1 (en) * 2003-11-12 2007-04-25 Symrise GmbH & Co. KG Mixture with wintergreen odor and flavor

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4136163A (en) * 1971-02-04 1979-01-23 Wilkinson Sword Limited P-menthane carboxamides having a physiological cooling effect
WO1993023005A1 (en) * 1992-05-18 1993-11-25 The Procter & Gamble Company Coolant compositions
WO2005049553A1 (en) * 2003-11-21 2005-06-02 Givaudan Sa N-substituted p-menthane carbosamided
WO2007019719A1 (en) * 2005-08-15 2007-02-22 Givaudan Sa Cooling compounds

Also Published As

Publication number Publication date
DE102008015428A1 (en) 2009-09-24
WO2009115165A2 (en) 2009-09-24

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