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WO2009107156A1 - Dispositif de diodes laser pour la détermination non invasive d’hormones thyroïdiennes - Google Patents

Dispositif de diodes laser pour la détermination non invasive d’hormones thyroïdiennes Download PDF

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Publication number
WO2009107156A1
WO2009107156A1 PCT/IT2008/000517 IT2008000517W WO2009107156A1 WO 2009107156 A1 WO2009107156 A1 WO 2009107156A1 IT 2008000517 W IT2008000517 W IT 2008000517W WO 2009107156 A1 WO2009107156 A1 WO 2009107156A1
Authority
WO
WIPO (PCT)
Prior art keywords
tsh
values
value
diode laser
finger
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/IT2008/000517
Other languages
English (en)
Inventor
Pietro Trombetta
Vittorio Londoni
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of WO2009107156A1 publication Critical patent/WO2009107156A1/fr
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/0059—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue
    • A61B5/14546—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue for measuring analytes not otherwise provided for, e.g. ions, cytochromes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/68—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
    • A61B5/6801—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be attached to or worn on the body surface
    • A61B5/6813—Specially adapted to be attached to a specific body part
    • A61B5/6825—Hand
    • A61B5/6826—Finger
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/68—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
    • A61B5/6801—Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be attached to or worn on the body surface
    • A61B5/683—Means for maintaining contact with the body
    • A61B5/6838—Clamps or clips

Definitions

  • 3 diode laser sources are involved, with wave lengths between 500 and 1000 run and powers between 0,ImW and 5mW.
  • the three incident rays are selectively absorbed by the presence of plasmic TSH, T3 and T4, thus determining the activation of thee specific photodiodes that can read the power difference from the starting emission value.
  • the device When switched on, the device activates the laser barrier, which, with only a passing of the finger and after a certain stabilization time, proceeds with a series of assessments calculating the average for each value.
  • the electric values of the photodiodes are transmitted under analog form to a microprocessor, with conversion into digital values and through a specific algorithm, with a calculation of the ratio among the values obtained, translated into plasmic TSH, T3 and T4 values, being the TSH value the control benchmark.
  • the device can be fed either through batteries or through cable, and a proper centring system places the finger under examination at the centre of the focus of the 3 rays.
  • the TSH, T3 and T4 values are displayed, together with the progressive number of assessment, the date and time on a graphic display and stored up to 5000 measurements.
  • the memory is downloadable on PC and workable on the same through the use of a proper software.

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Medical Informatics (AREA)
  • Surgery (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Pathology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Optics & Photonics (AREA)
  • Measuring And Recording Apparatus For Diagnosis (AREA)

Abstract

L’invention concerne un dispositif de diodes laser pour la détermination non invasive de valeurs plasmatiques de TSH, de T3 et de T4. Trois sources de diodes laser sont impliquées, ces sources présentant des longueurs d’ondes comprises entre 500 et 1000 nm et des puissances comprises entre 0,1 et 5 mW. Les trois rayons incidents sont absorbés de manière sélective par la présence de TSH, de T3 et de T4 plasmatiques, ce qui permet ainsi de déterminer l'activation de trois photodiodes spécifiques capables d’indiquer la différence de puissance par rapport à la valeur d'émission de départ. Les valeurs électriques des photodiodes sont transmises sous forme analogique à un microprocesseur, en étant converties en valeurs numériques à l’aide d’un algorithme spécifique, puis le rapport entre les valeurs obtenues est calculé, les valeurs étant traduites en valeurs de TSH, T3 et T4 plasmatiques, la valeur de TSH étant la valeur de référence. Le dispositif peut être alimenté au moyen de batteries ou de câbles, et un système de centrage approprié permet de placer le doigt soumis à l'examen au niveau du centre de convergence des 3 rayons.
PCT/IT2008/000517 2008-02-27 2008-07-30 Dispositif de diodes laser pour la détermination non invasive d’hormones thyroïdiennes Ceased WO2009107156A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
ITCO20080006 ITCO20080006A1 (it) 2008-02-27 2008-02-27 Dispositivo laser a diodi per la determinazione incruenta dei valori degli ormoni tiroidei
ITCO2008A000006 2008-02-27

Publications (1)

Publication Number Publication Date
WO2009107156A1 true WO2009107156A1 (fr) 2009-09-03

Family

ID=40084296

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IT2008/000517 Ceased WO2009107156A1 (fr) 2008-02-27 2008-07-30 Dispositif de diodes laser pour la détermination non invasive d’hormones thyroïdiennes

Country Status (2)

Country Link
IT (1) ITCO20080006A1 (fr)
WO (1) WO2009107156A1 (fr)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2313760B1 (fr) * 2008-07-30 2018-05-16 Zambaiti Parati S.P.A. Dispositif à laser à diode pour la mesure non invasive de la glycémie
CN113390977A (zh) * 2021-04-13 2021-09-14 杭州凯莱谱精准医疗检测技术有限公司 一种同时测定唾液中游离甲状腺激素T3、rT3、T4和皮质醇的方法

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1992000513A1 (fr) * 1990-06-27 1992-01-09 Futrex, Inc. Mesure non invasive de glycemie
WO2001028414A2 (fr) * 1999-10-20 2001-04-26 Kaufmann-Kim, Yun-Oak Dispositif pour determiner $m(f)i$m(g)in vivo$m(f)/i$m(g) de maniere non invasive la concentration de composants dans le sang ou dans des tissus organiques et pour etablir d'autres grandeurs pertinentes sur le plan medical
US20020095075A1 (en) * 1996-09-10 2002-07-18 Frank Madarasz Photonic molecular probe applications
WO2008111102A1 (fr) * 2007-03-09 2008-09-18 Vittorio Londoni Dispositif médical à diodes laser pour un dosage sans effusion de sang de la glycémie

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1992000513A1 (fr) * 1990-06-27 1992-01-09 Futrex, Inc. Mesure non invasive de glycemie
US20020095075A1 (en) * 1996-09-10 2002-07-18 Frank Madarasz Photonic molecular probe applications
WO2001028414A2 (fr) * 1999-10-20 2001-04-26 Kaufmann-Kim, Yun-Oak Dispositif pour determiner $m(f)i$m(g)in vivo$m(f)/i$m(g) de maniere non invasive la concentration de composants dans le sang ou dans des tissus organiques et pour etablir d'autres grandeurs pertinentes sur le plan medical
WO2008111102A1 (fr) * 2007-03-09 2008-09-18 Vittorio Londoni Dispositif médical à diodes laser pour un dosage sans effusion de sang de la glycémie

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2313760B1 (fr) * 2008-07-30 2018-05-16 Zambaiti Parati S.P.A. Dispositif à laser à diode pour la mesure non invasive de la glycémie
CN113390977A (zh) * 2021-04-13 2021-09-14 杭州凯莱谱精准医疗检测技术有限公司 一种同时测定唾液中游离甲状腺激素T3、rT3、T4和皮质醇的方法

Also Published As

Publication number Publication date
ITCO20080006A1 (it) 2009-08-28

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