[go: up one dir, main page]

WO2009151899A3 - Preparation of imatinib mesylate - Google Patents

Preparation of imatinib mesylate Download PDF

Info

Publication number
WO2009151899A3
WO2009151899A3 PCT/US2009/044587 US2009044587W WO2009151899A3 WO 2009151899 A3 WO2009151899 A3 WO 2009151899A3 US 2009044587 W US2009044587 W US 2009044587W WO 2009151899 A3 WO2009151899 A3 WO 2009151899A3
Authority
WO
WIPO (PCT)
Prior art keywords
imatinib mesylate
preparation
hygroscopic
preparing
processes
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/US2009/044587
Other languages
French (fr)
Other versions
WO2009151899A2 (en
Inventor
Rajasekhar Kadaboina
Munaswamy Sekhar Nariyam
Vijay Bhailalbhai Patel
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Dr Reddys Laboratories Ltd
Dr Reddys Laboratories Inc
Original Assignee
Dr Reddys Laboratories Ltd
Dr Reddys Laboratories Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dr Reddys Laboratories Ltd, Dr Reddys Laboratories Inc filed Critical Dr Reddys Laboratories Ltd
Priority to EP09763190A priority Critical patent/EP2291366A4/en
Publication of WO2009151899A2 publication Critical patent/WO2009151899A2/en
Publication of WO2009151899A3 publication Critical patent/WO2009151899A3/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)

Abstract

Processes for preparing a non-hygroscopic and stable crystalline alpha-form imatinib mesylate.
PCT/US2009/044587 2008-05-26 2009-05-20 Preparation of imatinib mesylate Ceased WO2009151899A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
EP09763190A EP2291366A4 (en) 2008-05-26 2009-05-20 Preparation of imatinib mesylate

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
IN1285CH2008 2008-05-26
IN1285/CHE/2008 2008-05-26
US9800308P 2008-09-18 2008-09-18
US61/098,003 2008-09-18

Publications (2)

Publication Number Publication Date
WO2009151899A2 WO2009151899A2 (en) 2009-12-17
WO2009151899A3 true WO2009151899A3 (en) 2010-02-25

Family

ID=41417346

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2009/044587 Ceased WO2009151899A2 (en) 2008-05-26 2009-05-20 Preparation of imatinib mesylate

Country Status (2)

Country Link
EP (1) EP2291366A4 (en)
WO (1) WO2009151899A2 (en)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL390611A1 (en) * 2010-03-04 2011-09-12 Tomasz Koźluk Process for the preparation of polymorphic alpha form and new polymorphic form of imatinib mesylate
WO2011158255A1 (en) * 2010-06-16 2011-12-22 Aptuit Laurus Private Limited Process for preparation of stable imatintb mesylate alpha form
WO2011157450A1 (en) 2010-06-18 2011-12-22 Krka, D. D., Novo Mesto New polymorphic form of imatinib base and preparation of salts thereof
EP2598499A2 (en) * 2010-07-29 2013-06-05 Dr. Reddy's Laboratories Ltd. Process for the preparation of imatinib mesylate
WO2012014000A1 (en) * 2010-07-30 2012-02-02 Ramesh Babu Potluri STABLE α-CRYSTAL FORM OF IMATINIB MESYLATE AND PREPARING PROCESS THEREOF
CN102477031B (en) * 2010-11-30 2015-07-15 浙江九洲药业股份有限公司 Method for preparing imatinib mesylate alfa crystal form
US8912325B2 (en) 2011-03-31 2014-12-16 Ind-Swift Laboratories Limited Process for preparation of imatinib and its mesylate salt
ITMI20111309A1 (en) 2011-07-14 2013-01-15 Italiana Sint Spa PREPARATION PROCEDURE OF IMATINIB MESILATO
IN2012DE00728A (en) 2012-03-13 2015-08-21 Fresenius Kabi Oncology Ltd
EP2749557A1 (en) 2012-12-31 2014-07-02 Deva Holding Anonim Sirketi Process for preparation of alpha polymorph of imatinib mesylate from IPA and THF solvate forms of imatinib mesylate
EP3007699A4 (en) * 2013-06-12 2017-01-18 Shilpa Medicare Limited Crystalline imatinib mesylate process
EP2927223B1 (en) 2014-04-04 2016-06-29 F.I.S.- Fabbrica Italiana Sintetici S.p.A. Process for preparing imatinib and salts thereof, free of genotoxic impurity f

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004106326A1 (en) * 2003-06-02 2004-12-09 Hetero Drugs Limited Novel polymorphs of imatinib mesylate
WO2006024863A1 (en) * 2004-09-02 2006-03-09 Cipla Limited Stable crystal form of imatinib mesylate and process for the preparation thereof
US20060223816A1 (en) * 2006-05-08 2006-10-05 Chemagis Ltd. Imatinib mesylate alpha form and production process therefor
US20080090833A1 (en) * 2006-04-27 2008-04-17 Alexandr Jegorov Polymorphic forms of imatinib mesylate and processes for preparation of novel crystalline forms as well as amorphous and form alpha

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004106326A1 (en) * 2003-06-02 2004-12-09 Hetero Drugs Limited Novel polymorphs of imatinib mesylate
WO2006024863A1 (en) * 2004-09-02 2006-03-09 Cipla Limited Stable crystal form of imatinib mesylate and process for the preparation thereof
US20080090833A1 (en) * 2006-04-27 2008-04-17 Alexandr Jegorov Polymorphic forms of imatinib mesylate and processes for preparation of novel crystalline forms as well as amorphous and form alpha
US20060223816A1 (en) * 2006-05-08 2006-10-05 Chemagis Ltd. Imatinib mesylate alpha form and production process therefor

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See also references of EP2291366A4 *

Also Published As

Publication number Publication date
EP2291366A4 (en) 2012-06-06
WO2009151899A2 (en) 2009-12-17
EP2291366A2 (en) 2011-03-09

Similar Documents

Publication Publication Date Title
WO2009151899A3 (en) Preparation of imatinib mesylate
EP2346837B8 (en) Methods of preparing quinazolinone derivatives
WO2007136510A3 (en) Polymorphic forms of imatinib mesylate and processes for their preparation as well as of amorphous imatinib mesylate and form alpha
WO2010014883A3 (en) Azacitidine process and polymorphs
SI2175857T1 (en) Crystalline form of (e) 4-ss4-ss4-(2-cyanoethenyl)-2,6-dimethylphenylcaminoc-2-pyrimidinylcaminocbenzonitrile
WO2012015999A3 (en) Process for the preparation of imatinib mesylate
IL237160A0 (en) Stabilized amorphous forms of imatinib mesylate
WO2010056656A3 (en) Preparation of crystalline palonosetron hydrochloride
EP2216333A3 (en) Crystalline forms of Dexlansoprazole
ZA201100760B (en) Process for the preparation of benzoimidazol-2-yl pyrimidine derivatives
AU2009254929A8 (en) An improved process for the preparation of amines
UA105767C2 (en) Amorphous prothioconazole, microbicidal composition based thereon, process for the preparation thereof
WO2010129636A3 (en) Lenalidomide polymorph
WO2011058525A3 (en) Processes for the preparation of erlotinib hydrochloride form a and erlotinib hydrochloride form b
WO2010065586A3 (en) Preparation of capecitabine
ZA201100759B (en) Process for the preparation of substituted pyrimidine derivatives
WO2010039885A3 (en) Crystalline forms of dexlansoprazole
WO2011023954A3 (en) Polymorphic forms of manidipine
WO2010027848A3 (en) Forms of lapatinib compounds and processes for the preparation thereof
WO2011018771A3 (en) Process for the preparation of valganciclovir hydrochloride
WO2010023676A3 (en) Process for preparing lamivudine polymorph form
WO2008150481A3 (en) Processes for the preparation of crystalline form beta of imatinib mesylate
WO2011100282A3 (en) Imatinib mesylate polymorphs
WO2009147626A3 (en) Anhydrous amorphous form of imatinib mesylate
WO2010146595A3 (en) Novel polymorphs of flibanserin hydrochloride

Legal Events

Date Code Title Description
121 Ep: the epo has been informed by wipo that ep was designated in this application

Ref document number: 09763190

Country of ref document: EP

Kind code of ref document: A2

WWE Wipo information: entry into national phase

Ref document number: 2009763190

Country of ref document: EP

NENP Non-entry into the national phase

Ref country code: DE

WWE Wipo information: entry into national phase

Ref document number: 7813/CHENP/2010

Country of ref document: IN