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WO2009141354A1 - Intraocular lens - Google Patents

Intraocular lens Download PDF

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Publication number
WO2009141354A1
WO2009141354A1 PCT/EP2009/056084 EP2009056084W WO2009141354A1 WO 2009141354 A1 WO2009141354 A1 WO 2009141354A1 EP 2009056084 W EP2009056084 W EP 2009056084W WO 2009141354 A1 WO2009141354 A1 WO 2009141354A1
Authority
WO
WIPO (PCT)
Prior art keywords
haptic
notches
optical portion
intraocular lens
optical
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/EP2009/056084
Other languages
French (fr)
Inventor
László KONTUR
Nándor TURKEVI-NAGY
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Medicontur Orvostechnikai Korlatolt Felelossegue Tarsasag
Original Assignee
Medicontur Orvostechnikai Korlatolt Felelossegue Tarsasag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Medicontur Orvostechnikai Korlatolt Felelossegue Tarsasag filed Critical Medicontur Orvostechnikai Korlatolt Felelossegue Tarsasag
Priority to JP2011509965A priority Critical patent/JP2011520541A/en
Priority to BRPI0912884A priority patent/BRPI0912884A2/en
Priority to EP09749844.8A priority patent/EP2326284B1/en
Priority to US12/993,487 priority patent/US20110112637A1/en
Priority to CN200980118640XA priority patent/CN102036621A/en
Publication of WO2009141354A1 publication Critical patent/WO2009141354A1/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/14—Eye parts, e.g. lenses or corneal implants; Artificial eyes
    • A61F2/16—Intraocular lenses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/14—Eye parts, e.g. lenses or corneal implants; Artificial eyes
    • A61F2/16—Intraocular lenses
    • A61F2/1613—Intraocular lenses having special lens configurations, e.g. multipart lenses; having particular optical properties, e.g. pseudo-accommodative lenses, lenses having aberration corrections, diffractive lenses, lenses for variably absorbing electromagnetic radiation, lenses having variable focus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/14—Eye parts, e.g. lenses or corneal implants; Artificial eyes
    • A61F2/16—Intraocular lenses
    • A61F2002/1681—Intraocular lenses having supporting structure for lens, e.g. haptics
    • A61F2002/1683—Intraocular lenses having supporting structure for lens, e.g. haptics having filiform haptics

Definitions

  • the present invention relates to an intraocular lens.
  • An intraocular lens has an optical portion, forming the correct optical correction system itself, and a haptic portion, which serves to place and secure the optic portion within the eye in the proper position.
  • Such a lens is generally made of a flexible material for folding or rolling, to be inserted into the eye by a small incision, the lens taking its shape and its normal dimensions when it is put into place in the eye.
  • Intraocular lenses must meet a number of mechanical constraints.
  • the haptic portion of the lens must be sufficiently flexible to stretch the capsular bag, whatever the size of the eye in which the lens is placed.
  • the haptic part of the lens must be sufficiently rigid in the optical plane to allow effective correction.
  • the shape of the intraocular lens must be adapted to limit the migration of cells, resulting in opacification of the posterior capsule (PCO).
  • PCO posterior capsule
  • a square edge is generally made on the entire periphery of the optical part.
  • intraocular lenses are generally made by milling and then turning. Milling makes it possible to cut the lens into a block of flexible material and to make the square edge on the periphery of the optical part. Then, the turning allows to realize the square edge at the level of the transitions between the optical part and the part haptic. This can lead to misalignment problems when changing tools.
  • the present invention aims to provide an intraocular lens that responds to these mechanical stresses, which avoids the problems of off-centering during manufacture and which limits the migration of cells.
  • the subject of the invention is an intraocular lens comprising an optical part and a haptic part, characterized in that it comprises, at each transition between said optical part and said haptic part, two notches, said two notches. being respectively disposed on either side of said transition, each notch extending along the edge of said haptic portion and encroaching on the periphery of said optical portion.
  • said haptic portion comprises two haptic assemblies arranged symmetrically with respect to the center of said optical portion, each of said two haptic assemblies comprising two handles, each of said two handles comprising a recessed portion surrounded by a rim .
  • each of said recessed portions is included in a triangle oriented so that the two axes surrounding the vertex of the triangle located on the side of said optical portion intersect a diameter of said optical portion, above the optical axis of said optical portion.
  • each of said recessed portions encroaches on the periphery of said optical portion.
  • said set of notches comprises four notches, each notch having a rounded shape, extending along the edge of one of said loops, and encroaching on the periphery of said optical portion.
  • said haptic part comprises two diametrically opposed elements, each of said two elements comprising a contact portion, intended to come into contact with the inner wall of the eye, and a connecting arm, connecting said element to the periphery of said optical portion.
  • said set of notches comprises at least two notches, each notch having an ovoid shape, extending along an edge of one of said connecting arms, and encroaching on the periphery of said optical portion.
  • FIG. 1 is a schematic simplified elevational view of the posterior face of an intraocular lens according to a first embodiment of the invention
  • Fig. 2 is an enlarged view of zone II of Fig. 1
  • FIG. 3 is a view similar to FIG. 1 specifying the shape of a loop of the haptic portion of the intraocular lens
  • Figure 4 is a view similar to Figure 1 showing an intraocular lens according to a second embodiment of the invention
  • FIG. 5 is an enlarged view of the zone V of FIG. 4.
  • FIG. 1 shows a single-piece flexible intraocular lens 1 according to a first embodiment of the invention.
  • the lens 1 is intended to be implanted in the capsular bag of an eye (not shown), in a manner known per se.
  • the intraocular lens 1 has an optical portion 2 and a haptic portion 3.
  • the intraocular lens 1 has a height H of about 9.74 mm, a width h of about 6.68 mm, and can be included in a circle of diameter D 1 approximately equal to 10.7 mm.
  • the dimensions of the intraocular lens 1 are adapted to the dimensions of a capsular bag.
  • the optical portion 2 is substantially circular and its diameter D is for example approximately equal to 6 mm.
  • the haptic portion 3 comprises two haptic assemblies 3a and 3b arranged symmetrically with respect to the center of the optical portion 2, that is to say with respect to the intersection of a diameter X, X 1 of the optical portion 2 and of a diameter Y, Y 1 of the optical portion 2.
  • the two haptics 3 a, 3b are identical, only the haptic 3a is described in detail below.
  • the haptic assembly 3a comprises two handles 4 and 5, each handle 4, 5 having a first end 4a, 5a, respectively, connected to the periphery of the optical portion 2 and a second end 4b, 5b, respectively, elastically deformable, intended coming into contact with the inner wall of the eye when the lens 1 is placed in the eye.
  • the two handles 4, 5 are arranged substantially symmetrically with respect to the diameter Y, Y '.
  • the haptic assembly 3a comprises a connecting strip 6 extending between the two handles 4 and 5 along the periphery of the optical portion 2.
  • Each handle 4, 5 comprises a recessed portion 7, 8, respectively, which is surrounded by an elastically deformable flange 9, 10, respectively.
  • Each flange 9, 10 has for example a width of about 0.22 mm.
  • each recessed portion 7, 8 is included in a triangle oriented so that the two axes A1 and A2 surrounding the vertex S 3 of the triangle located on the side of the optical portion 2 intersect the diameter YY 'above the optical axis O.
  • This shape and this orientation of the recessed portions 7, 8 have the effect of reducing the compression forces exerted on the handles 4, 5 when the lens 1 is placed in the eye. It has been found experimentally that the compressive forces are reduced by about a factor of two compared to the forces acting on intraocular lenses of the prior art.
  • this shape and orientation of the loops 4, 5 prevents or at least limits the presence of folds in the capsular bag, which avoids the migration of cells therefore the appearance of PCO (opacification of the posterior capsule).
  • Each recessed portion 7, 8 forms a notch 7a, 8a, respectively, which encroaches on the periphery of the optical portion 2, for example to a thickness of about 0.1 mm. This has the effect of reducing the risk of cell passage, thus the appearance of the PCO.
  • FIG. 2 shows in dashed lines an arc C1 of the same center as the optical part 2 to highlight the removal of material on the periphery of the optical portion 2, that is to say the notches 7a, 8a.
  • the lens 1 comprises, at each handle 4, 5, a notch 14, 15, respectively, of rounded shape, which extends along the edge of the handle 4, 5 and encroaches on the periphery of the optical part. 2, for example to a thickness of about 0.1 mm ( Figure 2).
  • the notches 14, 15 have three functions.
  • the lens 1 comprises, at each transition between the optical portion 2 and the haptic portion 3, two notches 7a, 8a, 14, 15.
  • the two notches 7a, 8a, 14, 15 are arranged respectively on either side of the transition, each notch 7a, 8a, 14, 15 extending along the edge of the haptic portion 3 and encroaching on the periphery of the optical portion 2.
  • the notches 14, 15 serve as centering means during the manufacture of the lens 1, which avoids the problems of off-centering when changing tools, and thus reduces the number of unusable lenses.
  • the notches 7a, 8a, 14, 15 allow to separate the line of work tools, that is to say, turning and milling, in several sectors. Each sector can thus be calibrated separately, which facilitates the centering.
  • notches 14, 15 has the effect of removing material, which has the effect of limiting the migration of cells, so the appearance of the PCO. Indeed, it has been found experimentally that the cells tend to migrate along the periphery of the optical part 2, then to pass on the lens 1 at a transition between the optical part 2 and the haptic part 3.
  • the notches 7a, 8a, 14, 15 allow to have for sure a square edge at level of this transition, and thus form a reservoir retaining the cells and preventing their migration on the lens 1.
  • the notches 14, 15 create a bending point allowing the handles 4, 5 to move outwardly at the time of the introduction of the lens 1, which improves the maintenance of the lens 1 in the capsular bag.
  • Figure 4 shows an intraocular lens 101 according to a second embodiment. Elements similar to the first embodiment have the same reference number and will not be described again.
  • the intraocular lens 101 has for example a height H of about 12.30 mm, a width h of about 6 mm, and can be included in a circle of diameter D 1 approximately equal to 13 mm.
  • the haptic portion 103 comprises two elements 103a and 103b diametrically opposed. The two elements 103a and 103b being identical, only the element 103a is described below.
  • the element 103a comprises a contact portion 120, intended to come into contact with the inner wall of the eye, and a connecting arm 121 connecting the element 103a to the periphery of the optical portion 2.
  • the lens 101 has a notch 122, of ovoid shape, which extends along an edge of the arm 121 and encroaches on the periphery of the optical portion 2.
  • the lens 101 has a notch 123, of ovoid shape, which extends along the other edge of the arm 121 and encroaches on the periphery of the optical portion 2.
  • the lens 101 therefore comprises, at each transition between the optical portion 2 and the haptic portion 103, two notches 122, 123.
  • the two notches 122 , 123 are disposed respectively on either side of the transition, each notch 122, 123 extending along the edge of the haptic portion 103 and encroaching on the periphery of the optical portion
  • FIG. 5 shows in dashed lines an arc of circle having the same center and the same radius as the optical portion 2 in order to highlight the material withdrawals on the periphery of the optical part 2.

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  • Health & Medical Sciences (AREA)
  • Ophthalmology & Optometry (AREA)
  • Cardiology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Transplantation (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Prostheses (AREA)

Abstract

Intraocular lens (1, 101) with an optic part (2) and a haptic part (3, 103), characterized in that it comprises, at each transition between said optic part (2) and said haptic part (3, 103), two notches (7a, 8a, 14, 15, 122, 123), said two notches (7a, 8a, 14, 15, 122, 123) being arranged respectively on either side of said transition, each notch (7a, 8a, 14, 15, 122, 123) extending along the edge of said haptic part (3, 103) and impinging on the periphery of said optic part (2).

Description

LENTILLE INTRAOCULAIRE INTRAOCULAR LENS

La présente invention a pour objet une lentille intraoculaire.The present invention relates to an intraocular lens.

Une lentille intraoculaire comporte une partie optique, formant le système optique correcteur proprement dit, et une partie haptique, qui sert à la mise en place et à la fixation de la partie optique à l'intérieur de l'œil dans la position convenable.An intraocular lens has an optical portion, forming the correct optical correction system itself, and a haptic portion, which serves to place and secure the optic portion within the eye in the proper position.

Une telle lentille est généralement réalisée dans un matériau souple permettant de la plier ou de la rouler, pour pouvoir l'insérer dans l'œil par une incision de taille réduite, la lentille reprenant sa forme et ses dimensions normales lorsqu'elle est mise en place dans l'œil.Such a lens is generally made of a flexible material for folding or rolling, to be inserted into the eye by a small incision, the lens taking its shape and its normal dimensions when it is put into place in the eye.

Les lentilles intraoculaires doivent répondre à un certain nombre de contraintes mécaniques. En particulier, la partie haptique de la lentille doit être suffisamment souple pour bien tendre le sac capsulaire quelque soit la taille de l'œil dans lequel la lentille est mise en place. La partie haptique de la lentille doit cependant être suffisamment rigide dans le plan optique pour permettre une correction efficace.Intraocular lenses must meet a number of mechanical constraints. In particular, the haptic portion of the lens must be sufficiently flexible to stretch the capsular bag, whatever the size of the eye in which the lens is placed. The haptic part of the lens, however, must be sufficiently rigid in the optical plane to allow effective correction.

La forme de la lentille intraoculaire doit être adaptée pour limiter la migration de cellules, celles-ci entraînant une opacification de la capsule postérieure (PCO). Pour lutter contre l' opacification de la capsule postérieure, on réalise en général un bord carré sur toute la périphérie de la partie optique.The shape of the intraocular lens must be adapted to limit the migration of cells, resulting in opacification of the posterior capsule (PCO). To fight against the opacification of the posterior capsule, a square edge is generally made on the entire periphery of the optical part.

Pour cette raison, les lentilles intraoculaires sont généralement réalisées par fraisage puis tournage. Le fraisage permet de découper la lentille dans un bloc de matériau souple et de réaliser le bord carré sur la périphérie de la partie optique. Puis, le tournage permet de réaliser le bord carré au niveau des transitions entre la partie optique et la partie haptique. Cela peut entraîner des problèmes de décentrage lors du changement d'outils.For this reason, intraocular lenses are generally made by milling and then turning. Milling makes it possible to cut the lens into a block of flexible material and to make the square edge on the periphery of the optical part. Then, the turning allows to realize the square edge at the level of the transitions between the optical part and the part haptic. This can lead to misalignment problems when changing tools.

La présente invention a pour but de proposer une lentille intraoculaire qui réponde à ces contraintes mécaniques, qui évite les problèmes de décentrage lors de la fabrication et qui limite la migration de cellules.The present invention aims to provide an intraocular lens that responds to these mechanical stresses, which avoids the problems of off-centering during manufacture and which limits the migration of cells.

A cet effet, l'invention a pour objet une lentille intraoculaire comportant une partie optique et une partie haptique, caractérisée en ce qu'elle comporte, au niveau de chaque transition entre ladite partie optique et ladite partie haptique, deux encoches, lesdites deux encoches étant disposées respectivement de part et d'autre de ladite transition, chaque encoche s 'étendant le long du bord de ladite partie haptique et empiétant sur la périphérie de ladite partie optique.For this purpose, the subject of the invention is an intraocular lens comprising an optical part and a haptic part, characterized in that it comprises, at each transition between said optical part and said haptic part, two notches, said two notches. being respectively disposed on either side of said transition, each notch extending along the edge of said haptic portion and encroaching on the periphery of said optical portion.

Selon un premier mode de réalisation de l'invention, ladite partie haptique comprend deux ensembles haptiques disposés symétriquement par rapport au centre de ladite partie optique, chacun desdits deux ensembles haptiques comportant deux anses, chacune desdites deux anses comprenant une portion évidée entourée par un rebord.According to a first embodiment of the invention, said haptic portion comprises two haptic assemblies arranged symmetrically with respect to the center of said optical portion, each of said two haptic assemblies comprising two handles, each of said two handles comprising a recessed portion surrounded by a rim .

De préférence, dans le premier mode de réalisation de l'invention, chacune desdites portions évidées est incluse dans un triangle orienté de manière que les deux axes entourant le sommet du triangle situé du côté de ladite partie optique coupent un diamètre de ladite partie optique, au dessus de l'axe optique de ladite partie optique.Preferably, in the first embodiment of the invention, each of said recessed portions is included in a triangle oriented so that the two axes surrounding the vertex of the triangle located on the side of said optical portion intersect a diameter of said optical portion, above the optical axis of said optical portion.

Avantageusement, dans le premier mode de réalisation de l'invention, chacune desdites portions évidées empiète sur la périphérie de ladite partie optique.Advantageously, in the first embodiment of the invention, each of said recessed portions encroaches on the periphery of said optical portion.

De préférence, dans le premier mode de réalisation de l'invention, ledit ensemble d'encoches comporte quatre encoches, chaque encoche présentant une forme arrondie, s' étendant le long du bord d'une desdites anses, et empiétant sur la périphérie de ladite partie optique.Preferably, in the first embodiment of the invention, said set of notches comprises four notches, each notch having a rounded shape, extending along the edge of one of said loops, and encroaching on the periphery of said optical portion.

Selon un deuxième mode de réalisation de l'invention, ladite partie haptique comprend deux éléments diamétralement opposés, chacun desdits deux éléments comportant une portion de contact, destinée à venir en contact avec la paroi interne de l'œil, et un bras de raccordement, raccordant ledit élément à la périphérie de ladite partie optique.According to a second embodiment of the invention, said haptic part comprises two diametrically opposed elements, each of said two elements comprising a contact portion, intended to come into contact with the inner wall of the eye, and a connecting arm, connecting said element to the periphery of said optical portion.

De préférence, dans le deuxième mode de réalisation de l'invention, ledit ensemble d'encoches comporte au moins deux encoches, chaque encoche présentant une forme ovoïde, s' étendant le long d'un bord d'un desdits bras de raccordement, et empiétant sur la périphérie de ladite partie optique.Preferably, in the second embodiment of the invention, said set of notches comprises at least two notches, each notch having an ovoid shape, extending along an edge of one of said connecting arms, and encroaching on the periphery of said optical portion.

L'invention sera mieux comprise, et d'autres buts, détails, caractéristiques et avantages de celle-ci apparaîtront plus clairement au cours de la description explicative détaillée qui va suivre, de plusieurs modes de réalisation de l'invention donnés à titre d'exemples purement illustratifs et non limitatifs, en référence aux dessins schématiques annexés. Sur ces dessins : la figure 1 est une vue schématique simplifiée en élévation de la face postérieure d'une lentille intraoculaire selon un premier mode de réalisation de l'invention ; la figure 2 est une vue agrandie de la zone II de la figure 1 ; - la figure 3 est une vue similaire à la figure 1 précisant la forme d'une anse de la partie haptique de la lentille intraoculaire ; la figure 4 est une vue similaire à la figure 1 montrant une lentille intraoculaire selon un deuxième mode de réalisation de l'invention ; et la figure 5 est une vue agrandie de la zone V de la figure 4.The invention will be better understood, and other objects, details, features and advantages thereof will become more clearly apparent in the following detailed explanatory description of several embodiments of the invention given as examples. purely illustrative and non-limiting examples, with reference to the attached schematic drawings. In these drawings: FIG. 1 is a schematic simplified elevational view of the posterior face of an intraocular lens according to a first embodiment of the invention; Fig. 2 is an enlarged view of zone II of Fig. 1; FIG. 3 is a view similar to FIG. 1 specifying the shape of a loop of the haptic portion of the intraocular lens; Figure 4 is a view similar to Figure 1 showing an intraocular lens according to a second embodiment of the invention; and FIG. 5 is an enlarged view of the zone V of FIG. 4.

La figure 1 montre une lentille intraoculaire souple monobloc 1 selon un premier mode de réalisation de l'invention. La lentille 1 est destinée à être implantée dans le sac capsulaire d'un œil (non représenté), d'une manière connue en soi.FIG. 1 shows a single-piece flexible intraocular lens 1 according to a first embodiment of the invention. The lens 1 is intended to be implanted in the capsular bag of an eye (not shown), in a manner known per se.

La lentille intraoculaire 1 comporte une partie optique 2 et une partie haptique 3. Par exemple, la lentille intraoculaire 1 présente une hauteur H d'environ 9,74 mm, une largeur h d'environ 6,68 mm, et peut être incluse dans un cercle de diamètre D1 environ égal à 10,7 mm. De manière générale, les dimensions de la lentille intraoculaire 1 sont adaptées aux dimensions d'un sac capsulaire. La partie optique 2 est sensiblement circulaire et son diamètre D est par exemple environ égal à 6 mm.The intraocular lens 1 has an optical portion 2 and a haptic portion 3. For example, the intraocular lens 1 has a height H of about 9.74 mm, a width h of about 6.68 mm, and can be included in a circle of diameter D 1 approximately equal to 10.7 mm. In general, the dimensions of the intraocular lens 1 are adapted to the dimensions of a capsular bag. The optical portion 2 is substantially circular and its diameter D is for example approximately equal to 6 mm.

La partie haptique 3 comprend deux ensembles haptiques 3a et 3b disposés symétriquement par rapport au centre de la partie optique 2, c'est-à-dire par rapport à l'intersection d'un diamètre X, X1 de la partie optique 2 et d'un diamètre Y, Y1 de la partie optique 2. Les deux ensembles haptiques 3 a, 3b étant identiques, seul l'ensemble haptique 3a est décrit en détails ci-dessous.The haptic portion 3 comprises two haptic assemblies 3a and 3b arranged symmetrically with respect to the center of the optical portion 2, that is to say with respect to the intersection of a diameter X, X 1 of the optical portion 2 and of a diameter Y, Y 1 of the optical portion 2. The two haptics 3 a, 3b are identical, only the haptic 3a is described in detail below.

L'ensemble haptique 3a comporte deux anses 4 et 5, chaque anse 4, 5 présentant une première extrémité 4a, 5a, respectivement, raccordée à la périphérie de la partie optique 2 et une deuxième extrémité 4b, 5b, respectivement, élastiquement déformable, destinée à venir au contact de la paroi interne de l'œil lorsque la lentille 1 est mise en place dans l'œil. Les deux anses 4, 5 sont disposées sensiblement symétriquement par rapport au diamètre Y, Y'. L'ensemble haptique 3a comporte une bande de liaison 6 s 'étendant entre les deux anses 4 et 5 le long de la périphérie de la partie optique 2. Chaque anse 4, 5 comprend une portion évidée 7, 8, respectivement, qui est entourée par un rebord élastiquement déformable 9, 10, respectivement. Chaque rebord 9, 10 a par exemple une largeur d'environ 0,22 mm. L'une des portions évidée 7, 8, par exemple la portion évidée 8, comprend un détrompeur 11. En se référant à la figure 3, on voit que chaque portion évidée 7, 8 est incluse dans un triangle orienté de manière que les deux axes Al et A2 entourant le sommet S 3 du triangle situé du côté de la partie optique 2 coupent le diamètre Y-Y' au dessus de l'axe optique O. Cette forme et cette orientation des portions évidées 7, 8 ont pour effet de réduire les forces de compression qui s'exercent sur les anses 4, 5 lorsque la lentille 1 est mise en place dans l'œil. Il a été constaté expérimentalement que les forces de compression sont réduites d'environ un facteur deux par rapport aux forces s'exerçant sur des lentilles intraoculaires de l'art antérieur. De plus, cette forme et cette orientation des anses 4, 5 empêche ou du moins limite la présence de plis dans le sac capsulaire, ce qui évite la migration de cellules donc l'apparition de la PCO (opacification de la capsule postérieure).The haptic assembly 3a comprises two handles 4 and 5, each handle 4, 5 having a first end 4a, 5a, respectively, connected to the periphery of the optical portion 2 and a second end 4b, 5b, respectively, elastically deformable, intended coming into contact with the inner wall of the eye when the lens 1 is placed in the eye. The two handles 4, 5 are arranged substantially symmetrically with respect to the diameter Y, Y '. The haptic assembly 3a comprises a connecting strip 6 extending between the two handles 4 and 5 along the periphery of the optical portion 2. Each handle 4, 5 comprises a recessed portion 7, 8, respectively, which is surrounded by an elastically deformable flange 9, 10, respectively. Each flange 9, 10 has for example a width of about 0.22 mm. One of the recessed portions 7, 8, for example the recessed portion 8, comprises a polarizer 11. Referring to FIG. 3, it can be seen that each recessed portion 7, 8 is included in a triangle oriented so that the two axes A1 and A2 surrounding the vertex S 3 of the triangle located on the side of the optical portion 2 intersect the diameter YY 'above the optical axis O. This shape and this orientation of the recessed portions 7, 8 have the effect of reducing the compression forces exerted on the handles 4, 5 when the lens 1 is placed in the eye. It has been found experimentally that the compressive forces are reduced by about a factor of two compared to the forces acting on intraocular lenses of the prior art. In addition, this shape and orientation of the loops 4, 5 prevents or at least limits the presence of folds in the capsular bag, which avoids the migration of cells therefore the appearance of PCO (opacification of the posterior capsule).

Chaque portion évidée 7, 8 forme une encoche 7a, 8a, respectivement, qui empiète sur la périphérie de la partie optique 2, par exemple sur une épaisseur d'environ 0,1 mm. Cela a pour effet de diminuer le risque de passage de cellules, donc l'apparition de la PCO. Sur la figure 2, on a représenté en traits interrompus un arc de cercle Cl de même centre que la partie optique 2 pour mettre en évidence le retrait de matière sur la périphérie de la partie optique 2, c'est-à-dire les encoches 7a, 8a.Each recessed portion 7, 8 forms a notch 7a, 8a, respectively, which encroaches on the periphery of the optical portion 2, for example to a thickness of about 0.1 mm. This has the effect of reducing the risk of cell passage, thus the appearance of the PCO. FIG. 2 shows in dashed lines an arc C1 of the same center as the optical part 2 to highlight the removal of material on the periphery of the optical portion 2, that is to say the notches 7a, 8a.

La lentille 1 comporte, au niveau de chaque anse 4, 5, une encoche 14, 15, respectivement, de forme arrondie, qui s'étend le long du bord de l'anse 4, 5 et empiète sur la périphérie de la partie optique 2, par exemple sur une épaisseur d'environ 0,1 mm (figure 2). Les encoches 14, 15 présentent trois fonctions.The lens 1 comprises, at each handle 4, 5, a notch 14, 15, respectively, of rounded shape, which extends along the edge of the handle 4, 5 and encroaches on the periphery of the optical part. 2, for example to a thickness of about 0.1 mm (Figure 2). The notches 14, 15 have three functions.

En d'autres termes, la lentille 1 comporte, au niveau de chaque transition entre la partie optique 2 et la partie haptique 3, deux encoches 7a, 8a, 14, 15. Les deux encoches 7a, 8a, 14, 15 sont disposées respectivement de part et d'autre de la transition, chaque encoche 7a, 8a, 14, 15 s 'étendant le long du bord de la partie haptique 3 et empiétant sur la périphérie de la partie optique 2.In other words, the lens 1 comprises, at each transition between the optical portion 2 and the haptic portion 3, two notches 7a, 8a, 14, 15. The two notches 7a, 8a, 14, 15 are arranged respectively on either side of the transition, each notch 7a, 8a, 14, 15 extending along the edge of the haptic portion 3 and encroaching on the periphery of the optical portion 2.

Premièrement, les encoches 14, 15 servent de moyens de centrage pendant la fabrication de la lentille 1, ce qui évite les problèmes de décentrage lors du changement d'outils, et permet donc de diminuer le nombre de lentilles non utilisables. En effet, les encoches 7a, 8a, 14, 15 permettent de séparer la ligne de travail des outils, c'est-à-dire du tournage et du fraisage, en plusieurs secteurs. Chaque secteur peut ainsi être calibré séparément, ce qui facilite le centrage.First, the notches 14, 15 serve as centering means during the manufacture of the lens 1, which avoids the problems of off-centering when changing tools, and thus reduces the number of unusable lenses. Indeed, the notches 7a, 8a, 14, 15 allow to separate the line of work tools, that is to say, turning and milling, in several sectors. Each sector can thus be calibrated separately, which facilitates the centering.

Deuxièmement, la présence d'encoches 14, 15 a pour conséquence la suppression de matière, ce qui a pour effet de limiter la migration de cellules, donc l'apparition de la PCO. En effet, il a été constaté expérimentalement que les cellules ont tendance à migrer le long de la périphérie de la partie optique 2, puis à passer sur la lentille 1 au niveau d'une transition entre la partie optique 2 et la partie haptique 3. Les encoches 7a, 8a, 14, 15 permettent d'avoir à coup sûr un bord carré au niveau de cette transition, et forment ainsi un réservoir retenant les cellules et empêchant leur migration sur la lentille 1.Second, the presence of notches 14, 15 has the effect of removing material, which has the effect of limiting the migration of cells, so the appearance of the PCO. Indeed, it has been found experimentally that the cells tend to migrate along the periphery of the optical part 2, then to pass on the lens 1 at a transition between the optical part 2 and the haptic part 3. The notches 7a, 8a, 14, 15 allow to have for sure a square edge at level of this transition, and thus form a reservoir retaining the cells and preventing their migration on the lens 1.

Troisièmement, les encoches 14, 15 créent un point de flexion permettant aux anses 4, 5 de s'écarter vers l'extérieur au moment de la mise en place de la lentille 1, ce qui permet d'améliorer le maintien de la lentille 1 dans le sac capsulaire.Third, the notches 14, 15 create a bending point allowing the handles 4, 5 to move outwardly at the time of the introduction of the lens 1, which improves the maintenance of the lens 1 in the capsular bag.

La figure 4 montre une lentille intraoculaire 101 selon un deuxième mode de réalisation. Les éléments similaires au premier mode de réalisation portent le même numéro de référence et ne seront pas décrits à nouveau.Figure 4 shows an intraocular lens 101 according to a second embodiment. Elements similar to the first embodiment have the same reference number and will not be described again.

Ici, la lentille intraoculaire 101 présente par exemple une hauteur H d'environ 12,30 mm, une largeur h d'environ 6 mm, et peut être incluse dans un cercle de diamètre D1 environ égal à 13 mm. la partie haptique 103 comprend deux éléments 103a et 103b diamétralement opposés. Les deux éléments 103a et 103b étant identiques, seul l'élément 103a est décrit ci-dessous. L'élément 103a comporte une portion de contact 120, destinée à venir en contact avec la paroi interne de l'œil, et un bras de raccordement 121 raccordant l'élément 103a à la périphérie de la partie optique 2. La lentille 101 comporte une encoche 122, de forme ovoïde, qui s'étend le long d'un bord du bras 121 et empiète sur la périphérie de la partie optique 2. La lentille 101 comporte une encoche 123, de forme ovoïde, qui s'étend le long de l'autre bord du bras 121 et empiète sur la périphérie de la partie optique 2. La lentille 101 comporte donc, au niveau de chaque transition entre la partie optique 2 et la partie haptique 103, deux encoches 122, 123. Les deux encoches 122, 123 sont disposées respectivement de part et d'autre de la transition, chaque encoche 122, 123 s'étendant le long du bord de la partie haptique 103 et empiétant sur la périphérie de la partie optiqueHere, the intraocular lens 101 has for example a height H of about 12.30 mm, a width h of about 6 mm, and can be included in a circle of diameter D 1 approximately equal to 13 mm. the haptic portion 103 comprises two elements 103a and 103b diametrically opposed. The two elements 103a and 103b being identical, only the element 103a is described below. The element 103a comprises a contact portion 120, intended to come into contact with the inner wall of the eye, and a connecting arm 121 connecting the element 103a to the periphery of the optical portion 2. The lens 101 has a notch 122, of ovoid shape, which extends along an edge of the arm 121 and encroaches on the periphery of the optical portion 2. The lens 101 has a notch 123, of ovoid shape, which extends along the other edge of the arm 121 and encroaches on the periphery of the optical portion 2. The lens 101 therefore comprises, at each transition between the optical portion 2 and the haptic portion 103, two notches 122, 123. The two notches 122 , 123 are disposed respectively on either side of the transition, each notch 122, 123 extending along the edge of the haptic portion 103 and encroaching on the periphery of the optical portion

2.2.

Les encoches 122 et 123 présentent les mêmes fonctions que les encoches 14, 15 décrites précédemment. Sur la figure 5, on a représenté en traits interrompus un arc de cercle de même centre et de même rayon que la partie optique 2 pour mettre en évidence les retraits de matière sur la périphérie de la partie optique 2.The notches 122 and 123 have the same functions as the notches 14, 15 described above. FIG. 5 shows in dashed lines an arc of circle having the same center and the same radius as the optical portion 2 in order to highlight the material withdrawals on the periphery of the optical part 2.

Bien que l'invention ait été décrite en relation avec plusieurs modes de réalisation particuliers, il est bien évident qu'elle n'y est nullement limitée et qu'elle comprend tous les équivalents techniques des moyens décrits ainsi que leurs combinaisons si celles-ci entrent dans le cadre de l'invention. Although the invention has been described in connection with several particular embodiments, it is obvious that it is not limited thereto and that it comprises all the technical equivalents of the means described and their combinations if they are within the scope of the invention.

Claims

REVENDICATIONS 1. Lentille intraoculaire (1, 101) comportant une partie optique (2) et une partie haptique (3, 103), caractérisée en ce qu'elle comporte, au niveau de chaque transition entre ladite partie optique (2) et ladite partie haptique (3, 103), deux encoches (7a, 8a, 14, 15, 122, 123), lesdites deux encoches (7a, 8a, 14, 15, 122, 123) étant disposées respectivement de part et d'autre de ladite transition, chaque encoche (7a, 8a, 14, 15,1. Intraocular lens (1, 101) having an optical portion (2) and a haptic portion (3, 103), characterized in that it comprises, at each transition between said optical portion (2) and said haptic portion (3, 103), two notches (7a, 8a, 14, 15, 122, 123), said two notches (7a, 8a, 14, 15, 122, 123) being disposed respectively on either side of said transition each notch (7a, 8a, 14, 15, 122, 123) s'étendant le long du bord de ladite partie haptique (3, 103) et empiétant sur la périphérie de ladite partie optique (2).122, 123) extending along the edge of said haptic portion (3, 103) and encroaching on the periphery of said optical portion (2). 2. Lentille intraoculaire selon la revendication 1 , caractérisée en ce que ladite partie haptique (3) comprend deux ensembles haptiques (3a, 3b) disposés symétriquement par rapport au centre de ladite partie optique (2), chacun desdits deux ensembles haptiques comportant deux anses (4, 5), chacune desdites deux anses comprenant une portion évidée (7, 8) entourée par un rebord (9, 10).2. Intraocular lens according to claim 1, characterized in that said haptic portion (3) comprises two haptic assemblies (3a, 3b) arranged symmetrically with respect to the center of said optical portion (2), each of said two haptic assemblies having two handles (4, 5), each of said two handles including a recessed portion (7, 8) surrounded by a flange (9, 10). 3. Lentille intraoculaire selon la revendication 2, caractérisée en ce que chacune desdites portions évidées (7, 8) est incluse dans un triangle orienté de manière que les deux axes (Al, A2) entourant le sommet (S3) du triangle situé du côté de ladite partie optique (2) coupent un diamètre (YY') de ladite partie optique, au dessus de l'axe optique (O) de ladite partie optique. 3. Intraocular lens according to claim 2, characterized in that each of said recessed portions (7, 8) is included in a triangle oriented so that the two axes (Al, A2) surrounding the vertex (S3) of the triangle on the side said optical portion (2) intersects a diameter (YY ') of said optical portion, above the optical axis (O) of said optical portion. 4. Lentille intraoculaire selon la revendication 2 ou 3, caractérisé en ce que chacune desdites portions évidées (7, 8) empiète sur la périphérie de ladite partie optique (2).4. Intraocular lens according to claim 2 or 3, characterized in that each of said recessed portions (7, 8) encroaches on the periphery of said optical portion (2). 5. Lentille intraoculaire selon l'une quelconque des revendications 2 à 4, caractérisée en ce que ledit ensemble d'encoches comporte quatre encoches (14, 15), chaque encoche présentant une forme arrondie, s' étendant le long du bord d'une desdites anses (4, 5), et empiétant sur la périphérie de ladite partie optique (2). Intraocular lens according to any one of claims 2 to 4, characterized in that said set of notches has four notches (14, 15), each notch having a rounded shape, extending along the edge of an said loops (4, 5), and encroaching on the periphery of said optical portion (2). 6. Lentille intraoculaire selon la revendication 1, caractérisé en ce que ladite partie haptique (103) comprend deux éléments (103a, 103b) diamétralement opposés, chacun desdits deux éléments comportant une portion de contact (120), destinée à venir en contact avec la paroi interne de l'œil, et un bras de raccordement (121), raccordant ledit élément à la périphérie de ladite partie optique (2).6. Intraocular lens according to claim 1, characterized in that said haptic portion (103) comprises two elements (103a, 103b) diametrically opposed, each of said two elements comprising a contact portion (120) intended to come into contact with the inner wall of the eye, and a connecting arm (121), connecting said element to the periphery of said optical portion (2). 7. Lentille intraoculaire selon la revendication 6, caractérisé en ce que ledit ensemble d'encoches comporte au moins deux encoches (122, 123), chaque encoche présentant une forme ovoïde, s' étendant le long d'un bord d'un desdits bras de raccordement (121), et empiétant sur la périphérie de ladite partie optique (2). Intraocular lens according to claim 6, characterized in that said set of notches comprises at least two notches (122, 123), each notch having an ovoid shape, extending along an edge of one of said arms. connection (121), and encroaching on the periphery of said optical portion (2).
PCT/EP2009/056084 2008-05-21 2009-05-19 Intraocular lens Ceased WO2009141354A1 (en)

Priority Applications (5)

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JP2011509965A JP2011520541A (en) 2008-05-21 2009-05-19 Intraocular lens
BRPI0912884A BRPI0912884A2 (en) 2008-05-21 2009-05-19 intraocular lens.
EP09749844.8A EP2326284B1 (en) 2008-05-21 2009-05-19 Intraocular lens
US12/993,487 US20110112637A1 (en) 2008-05-21 2009-05-19 Intraocular lens
CN200980118640XA CN102036621A (en) 2008-05-21 2009-05-19 Intraocular lens

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FR0802761A FR2931356B1 (en) 2008-05-21 2008-05-21 INTRAOCULAR LENS
FR0802761 2008-05-21

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EP (1) EP2326284B1 (en)
JP (1) JP2011520541A (en)
CN (1) CN102036621A (en)
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FR (1) FR2931356B1 (en)
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WO2019130029A1 (en) * 2017-12-28 2019-07-04 Medicontour Medical Engineering Ltd. Lens case for intraocular lenses with haptics
DE102020108381B3 (en) * 2020-03-26 2021-05-27 Carl Zeiss Meditec Ag Intraocular lens with a snap-in projection and a snap-in recess to avoid an axial offset

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EP0413057A1 (en) * 1989-08-18 1991-02-20 Chiron Adatomed Pharmazeutische und Medizintechnische Gesellschaft mbH Posterior chamber intraocular lens
US5047052A (en) * 1987-11-06 1991-09-10 Seymour Dubroff Anterior chamber intraocular lens with four point fixation
FR2814671A1 (en) * 2000-10-02 2002-04-05 Biotech Intraocular lens has haptic loops with axes of sides meeting at points not aligned with centre of lens
FR2819713A1 (en) * 2001-01-25 2002-07-26 Corneal Ind Integral intraocular implant has optic with pair of haptics having arms with ends connected by cord of reduced width
FR2858544A1 (en) 2003-08-04 2005-02-11 Corneal Ind Intra-ocular lens for capsular sac, has contact end presenting contact edge, on anterior part of sac, arranged on concentric circle at optical part, and common part making angle with respect to optical plane
FR2876275A1 (en) * 2004-10-08 2006-04-14 Humanoptics Ag Ag ACCOMMODATIVE INTRAOCULAR IMPLANT

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JPWO2008041683A1 (en) * 2006-10-04 2010-02-04 Hoya株式会社 Soft intraocular lens

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EP0195881A1 (en) * 1985-03-27 1986-10-01 Pharmacia Ab Intraocular lens
EP0246216A2 (en) * 1986-05-14 1987-11-19 Precision-Cosmet Co., Inc. Intraocular lens with tapered haptics
US5047052A (en) * 1987-11-06 1991-09-10 Seymour Dubroff Anterior chamber intraocular lens with four point fixation
EP0413057A1 (en) * 1989-08-18 1991-02-20 Chiron Adatomed Pharmazeutische und Medizintechnische Gesellschaft mbH Posterior chamber intraocular lens
FR2814671A1 (en) * 2000-10-02 2002-04-05 Biotech Intraocular lens has haptic loops with axes of sides meeting at points not aligned with centre of lens
FR2819713A1 (en) * 2001-01-25 2002-07-26 Corneal Ind Integral intraocular implant has optic with pair of haptics having arms with ends connected by cord of reduced width
FR2858544A1 (en) 2003-08-04 2005-02-11 Corneal Ind Intra-ocular lens for capsular sac, has contact end presenting contact edge, on anterior part of sac, arranged on concentric circle at optical part, and common part making angle with respect to optical plane
FR2876275A1 (en) * 2004-10-08 2006-04-14 Humanoptics Ag Ag ACCOMMODATIVE INTRAOCULAR IMPLANT

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RU2010146966A (en) 2012-06-27
US20110112637A1 (en) 2011-05-12
CN102036621A (en) 2011-04-27
FR2931356A1 (en) 2009-11-27
JP2011520541A (en) 2011-07-21
FR2931356B1 (en) 2016-07-01
EP2326284A1 (en) 2011-06-01
BRPI0912884A2 (en) 2015-10-20
EP2326284B1 (en) 2016-04-20

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