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WO2009039102A8 - Inhibitors of copn (cpn) for the treatment of bacterial infections - Google Patents

Inhibitors of copn (cpn) for the treatment of bacterial infections Download PDF

Info

Publication number
WO2009039102A8
WO2009039102A8 PCT/US2008/076538 US2008076538W WO2009039102A8 WO 2009039102 A8 WO2009039102 A8 WO 2009039102A8 US 2008076538 W US2008076538 W US 2008076538W WO 2009039102 A8 WO2009039102 A8 WO 2009039102A8
Authority
WO
WIPO (PCT)
Prior art keywords
copn
cpn
inhibitors
bacterial infections
treatment
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/US2008/076538
Other languages
French (fr)
Other versions
WO2009039102A1 (en
Inventor
Jin Huang
Stephen Lory
Cammie F Lesser
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
General Hospital Corp
Harvard University
Original Assignee
General Hospital Corp
Harvard University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by General Hospital Corp, Harvard University filed Critical General Hospital Corp
Publication of WO2009039102A1 publication Critical patent/WO2009039102A1/en
Publication of WO2009039102A8 publication Critical patent/WO2009039102A8/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/41921,2,3-Triazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/4365Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system having sulfur as a ring hetero atom, e.g. ticlopidine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

This invention features compounds which are inhibitors of CopN(Cpn) and their use for treating bacterial infections in humans and animals.
PCT/US2008/076538 2007-09-17 2008-09-16 Inhibitors of copn (cpn) for the treatment of bacterial infections Ceased WO2009039102A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US99410507P 2007-09-17 2007-09-17
US60/994,105 2007-09-17

Publications (2)

Publication Number Publication Date
WO2009039102A1 WO2009039102A1 (en) 2009-03-26
WO2009039102A8 true WO2009039102A8 (en) 2009-05-14

Family

ID=40468287

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2008/076538 Ceased WO2009039102A1 (en) 2007-09-17 2008-09-16 Inhibitors of copn (cpn) for the treatment of bacterial infections

Country Status (1)

Country Link
WO (1) WO2009039102A1 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6627686B1 (en) 2000-09-06 2003-09-30 The Goodyear Tire & Rubber Company Diaryl-p-phenylenediamine disulfides

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9302016D0 (en) * 1993-02-02 1993-03-17 Sandoz Ltd Compounds
JP3853985B2 (en) * 1998-08-03 2006-12-06 有限会社 健康百二十才 Disinfectant containing iron ions
WO2003039418A1 (en) * 2001-11-06 2003-05-15 Maxim Pharmaceuticals, Inc. Compositions for the treatment of infectious diseases

Also Published As

Publication number Publication date
WO2009039102A1 (en) 2009-03-26

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