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WO2009035160A8 - Candidate molecule for falciparum malaria vaccine - Google Patents

Candidate molecule for falciparum malaria vaccine Download PDF

Info

Publication number
WO2009035160A8
WO2009035160A8 PCT/JP2008/066934 JP2008066934W WO2009035160A8 WO 2009035160 A8 WO2009035160 A8 WO 2009035160A8 JP 2008066934 W JP2008066934 W JP 2008066934W WO 2009035160 A8 WO2009035160 A8 WO 2009035160A8
Authority
WO
WIPO (PCT)
Prior art keywords
malaria vaccine
candidate molecule
falciparum malaria
acid sequence
amino acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/JP2008/066934
Other languages
French (fr)
Japanese (ja)
Other versions
WO2009035160A1 (en
Inventor
謙二 平山
シュアイブ、モハメド・ナシール
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Nagasaki University NUC
Original Assignee
Nagasaki University NUC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nagasaki University NUC filed Critical Nagasaki University NUC
Priority to JP2009532271A priority Critical patent/JP5354542B2/en
Publication of WO2009035160A1 publication Critical patent/WO2009035160A1/en
Publication of WO2009035160A8 publication Critical patent/WO2009035160A8/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/002—Protozoa antigens
    • A61K39/015—Hemosporidia antigens, e.g. Plasmodium antigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • A61P33/06—Antimalarials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/53—DNA (RNA) vaccination
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

It is intended to provide a malaria vaccine which contains one member selected from among the following substances (1) to (3): (1) a polypeptide containing the amino acid sequence of malaria parasite GPI8P transamidase; (2) a polypeptide containing a partial amino acid sequence of malaria parasite GPI8P transamidase, wherein the partial amino acid sequence consists of six or more amino acids, and having an immunogenicity; and (3) an expression vector which is capable of expressing the polypeptide (1) or (2).
PCT/JP2008/066934 2007-09-14 2008-09-12 Candidate molecule for falciparum malaria vaccine Ceased WO2009035160A1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2009532271A JP5354542B2 (en) 2007-09-14 2008-09-12 P. falciparum vaccine candidate molecule

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2007-239488 2007-09-14
JP2007239488 2007-09-14

Publications (2)

Publication Number Publication Date
WO2009035160A1 WO2009035160A1 (en) 2009-03-19
WO2009035160A8 true WO2009035160A8 (en) 2009-09-24

Family

ID=40452152

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/JP2008/066934 Ceased WO2009035160A1 (en) 2007-09-14 2008-09-12 Candidate molecule for falciparum malaria vaccine

Country Status (2)

Country Link
JP (1) JP5354542B2 (en)
WO (1) WO2009035160A1 (en)

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4651213B2 (en) * 2001-03-27 2011-03-16 株式会社グライコメディクス Influenza virus hemagglutinin-binding peptide
CA2505067C (en) * 2002-11-22 2011-08-02 Eisai Co., Ltd. Methods of screening for compounds that inhibit the biosynthesis of gpi in malaria parasites

Also Published As

Publication number Publication date
WO2009035160A1 (en) 2009-03-19
JP5354542B2 (en) 2013-11-27
JPWO2009035160A1 (en) 2010-12-24

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