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WO2009034951A1 - ステロイドホルモンの定量方法 - Google Patents

ステロイドホルモンの定量方法 Download PDF

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Publication number
WO2009034951A1
WO2009034951A1 PCT/JP2008/066187 JP2008066187W WO2009034951A1 WO 2009034951 A1 WO2009034951 A1 WO 2009034951A1 JP 2008066187 W JP2008066187 W JP 2008066187W WO 2009034951 A1 WO2009034951 A1 WO 2009034951A1
Authority
WO
WIPO (PCT)
Prior art keywords
steroid hormone
skin
quantification
estrogen
horny layer
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/JP2008/066187
Other languages
English (en)
French (fr)
Inventor
Noriko Haketa
Shingo Kakuo
Seijiro Honma
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Kao Corp
Original Assignee
Kao Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kao Corp filed Critical Kao Corp
Priority to US12/676,226 priority Critical patent/US8017404B2/en
Priority to EP08830449A priority patent/EP2189788A4/en
Priority to CN200880106828A priority patent/CN101802606A/zh
Publication of WO2009034951A1 publication Critical patent/WO2009034951A1/ja
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/74—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving hormones or other non-cytokine intercellular protein regulatory factors such as growth factors, including receptors to hormones and growth factors
    • G01N33/743—Steroid hormones
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
    • G01N33/6848—Methods of protein analysis involving mass spectrometry
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/88—Integrated analysis systems specially adapted therefor, not covered by a single one of the groups G01N30/04 - G01N30/86
    • G01N2030/8809—Integrated analysis systems specially adapted therefor, not covered by a single one of the groups G01N30/04 - G01N30/86 analysis specially adapted for the sample
    • G01N2030/8813—Integrated analysis systems specially adapted therefor, not covered by a single one of the groups G01N30/04 - G01N30/86 analysis specially adapted for the sample biological materials
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02—Column chromatography
    • G01N30/88—Integrated analysis systems specially adapted therefor, not covered by a single one of the groups G01N30/04 - G01N30/86
    • G01N2030/8809—Integrated analysis systems specially adapted therefor, not covered by a single one of the groups G01N30/04 - G01N30/86 analysis specially adapted for the sample
    • G01N2030/8813—Integrated analysis systems specially adapted therefor, not covered by a single one of the groups G01N30/04 - G01N30/86 analysis specially adapted for the sample biological materials
    • G01N2030/8831—Integrated analysis systems specially adapted therefor, not covered by a single one of the groups G01N30/04 - G01N30/86 analysis specially adapted for the sample biological materials involving peptides or proteins
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/20—Oxygen containing

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Physics & Mathematics (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Endocrinology (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
  • Sampling And Sample Adjustment (AREA)

Abstract

テープストリッピング法により採取された皮膚角質層からステロイドホルモンをＬＣ－ＭＳで分析することにより皮膚角質層中のエストロゲンをはじめとするステロイドホルモンを定量する。これにより、皮膚性状に重要な働きを有するエストロゲンをはじめとするステロイドホルモンの皮膚中の濃度を、簡便に測定できるようにする。  
PCT/JP2008/066187 2007-09-12 2008-09-08 ステロイドホルモンの定量方法 Ceased WO2009034951A1 (ja)

Priority Applications (3)

Application Number Priority Date Filing Date Title
US12/676,226 US8017404B2 (en) 2007-09-12 2008-09-08 Steroid hormone assay method
EP08830449A EP2189788A4 (en) 2007-09-12 2008-09-08 METHOD FOR QUANTIFYING STEROID HORMONE
CN200880106828A CN101802606A (zh) 2007-09-12 2008-09-08 类固醇激素的定量方法

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2007-236250 2007-09-12
JP2007236250 2007-09-12

Publications (1)

Publication Number Publication Date
WO2009034951A1 true WO2009034951A1 (ja) 2009-03-19

Family

ID=40451958

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/JP2008/066187 Ceased WO2009034951A1 (ja) 2007-09-12 2008-09-08 ステロイドホルモンの定量方法

Country Status (5)

Country Link
US (1) US8017404B2 (ja)
EP (1) EP2189788A4 (ja)
JP (1) JP2009085946A (ja)
CN (1) CN101802606A (ja)
WO (1) WO2009034951A1 (ja)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2020143915A (ja) * 2019-03-04 2020-09-10 花王株式会社 ステロイドホルモンの調製又は定量方法

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101467371B1 (ko) * 2010-12-14 2014-12-02 주식회사 피코팜 타액 정제 방법
WO2012081911A2 (ko) * 2010-12-14 2012-06-21 퍼팩트코리아(주) 타액 정제 방법
JP6012635B2 (ja) * 2011-02-07 2016-10-25 ラボラトリー コーポレイション オブ アメリカ ホールディングス サンプル中のテストステロンの存在または量を決定するための方法およびシステム
JP6041125B2 (ja) * 2012-07-06 2016-12-07 株式会社あすか製薬メディカル エストロゲンの超高感度測定法
WO2014015439A1 (en) * 2012-07-26 2014-01-30 Miraculins Inc. Titration of therapy through assay of cholesterol in skin by mass spectroscopy
GB201215924D0 (en) * 2012-09-06 2012-10-24 Univ Swansea Kit and method for quantitative detection of steroids
JP5811973B2 (ja) 2012-09-12 2015-11-11 住友電気工業株式会社 炭化珪素半導体装置の製造方法
JP2014056913A (ja) 2012-09-12 2014-03-27 Sumitomo Electric Ind Ltd 炭化珪素半導体装置
JP6056292B2 (ja) * 2012-09-12 2017-01-11 住友電気工業株式会社 炭化珪素半導体装置の製造方法
CN103698414B (zh) * 2012-09-27 2014-12-03 中国科学院大连化学物理研究所 一种基于化学衍生的尿液中甾体激素的检测方法
JP6105252B2 (ja) * 2012-10-26 2017-03-29 株式会社コーセー 皮膚内挙動評価方法
CN103336065A (zh) * 2013-01-15 2013-10-02 东南大学 一种同时提取和检测生物介质中多种激素及其代谢物的方法
CN103267820B (zh) * 2013-04-28 2015-06-17 河海大学 一种污泥中多种雌激素的共检测方法
CN104458929B (zh) * 2013-09-24 2016-12-07 山东绿叶制药有限公司 一种检测促性腺激素释放激素类似物和睾酮的测定方法
KR20180078243A (ko) * 2015-11-05 2018-07-09 가부시키가이샤 시세이도 각질층 채취구 및 각질층 채취 검출용 키트
CN106918467A (zh) * 2017-04-14 2017-07-04 长庆石油勘探局技术监测中心 一种逐层采集铁基材料腐蚀产物的方法
CN107894454B (zh) * 2017-11-14 2018-12-25 长春中医药大学 一种快速无损诊断乳腺疾病的质谱分析模型
CN108931603A (zh) * 2018-04-23 2018-12-04 国家烟草质量监督检验中心 一种基于稳定同位素标记质谱联用技术检测血浆中羧酸类代谢物的方法

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2006138786A (ja) 2004-11-15 2006-06-01 Aska Pharmaceutical Co Ltd 生体内微量エストラジオールの新規測定法
JP2007108060A (ja) * 2005-10-14 2007-04-26 Kao Corp 肌質の評価方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2489270C (en) * 2002-06-11 2012-08-07 Pantarhei Bioscience B.V. A method of treating human skin and a skin care composition for use in such a method
US7238494B2 (en) * 2004-04-30 2007-07-03 Imi International Medical Innovations, Inc. Direct assay of cholesterol in skin samples removed by tape stripping
US20050272112A1 (en) * 2004-04-28 2005-12-08 Imi International Medical Innovations, Inc. Direct assay of cholesterol in skin removed by tape stripping

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2006138786A (ja) 2004-11-15 2006-06-01 Aska Pharmaceutical Co Ltd 生体内微量エストラジオールの新規測定法
JP2007108060A (ja) * 2005-10-14 2007-04-26 Kao Corp 肌質の評価方法

Non-Patent Citations (5)

* Cited by examiner, † Cited by third party
Title
KAZUO IMAEDA,ET AL.: "Rat Hihyo Shishitsu Seibun ni Taisuru Sei Hormone no Eikyo", FOLIA PHARMACOLOGICA JAPONICA, vol. 90, no. 3, 1 September 1987 (1987-09-01), pages 147 - 153 *
LYNN K. PERSHING,ET AL.: "Feasibility of measuring the bioavailability of topical betamethasone dipropionate in commercial formulations using drug content in skin and a skin blanching bioassay", PHARMACEUTICAL RESEARCH, vol. 9, no. 1, January 1992 (1992-01-01), pages 45 - 51, XP008130179 *
MUHAMMAD ATIF KHAN,ET AL.: "Analysis of Derivatised Steroids by Matrix-Assisted Laser Desorption/Ionisation and Post-Source Decay Mass Spectrometry", STEROIDS, vol. 71, no. 1, January 2006 (2006-01-01), pages 42 - 53, XP025127869 *
See also references of EP2189788A4 *
WILLIAM J. GRIFFITHS: "Derivatisation for the characterisation of neutral oxosteroids by electrospray and matrix-assisted laser desorption/ionisation tandem mass spectrometry: the Girard P derivative", RAPID COMMUNICATIONS IN MASS SPECTROMETRY, vol. 17, no. 9, 2003, pages 924 - 935, XP008130180 *

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2020143915A (ja) * 2019-03-04 2020-09-10 花王株式会社 ステロイドホルモンの調製又は定量方法
JP7292058B2 (ja) 2019-03-04 2023-06-16 花王株式会社 ステロイドホルモンの調製又は定量方法

Also Published As

Publication number Publication date
JP2009085946A (ja) 2009-04-23
EP2189788A1 (en) 2010-05-26
US20100184095A1 (en) 2010-07-22
EP2189788A4 (en) 2010-10-13
CN101802606A (zh) 2010-08-11
US8017404B2 (en) 2011-09-13

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