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WO2009034582A3 - Procédé pour la préparation de chlorhydrate de fexofénadine amorphe - Google Patents

Procédé pour la préparation de chlorhydrate de fexofénadine amorphe Download PDF

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Publication number
WO2009034582A3
WO2009034582A3 PCT/IN2008/000581 IN2008000581W WO2009034582A3 WO 2009034582 A3 WO2009034582 A3 WO 2009034582A3 IN 2008000581 W IN2008000581 W IN 2008000581W WO 2009034582 A3 WO2009034582 A3 WO 2009034582A3
Authority
WO
WIPO (PCT)
Prior art keywords
preparation
fexofenadine hydrochloride
amorphous
amorphous fexofenadine
fexofenadine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/IN2008/000581
Other languages
English (en)
Other versions
WO2009034582A2 (fr
Inventor
Chidambaram Venkateswaran Srinivasan
Perminder Singh Johar
Lalit Wadhwa
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
IND-SWIFT LABORATORIES Ltd
Ind Swift Laboratories Ltd
Original Assignee
IND-SWIFT LABORATORIES Ltd
Ind Swift Laboratories Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by IND-SWIFT LABORATORIES Ltd, Ind Swift Laboratories Ltd filed Critical IND-SWIFT LABORATORIES Ltd
Publication of WO2009034582A2 publication Critical patent/WO2009034582A2/fr
Anticipated expiration legal-status Critical
Publication of WO2009034582A3 publication Critical patent/WO2009034582A3/fr
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
    • C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D211/20—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms
    • C07D211/22—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by singly bound oxygen or sulphur atoms by oxygen atoms

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

La présente invention concerne un procédé pour la préparation de chlorhydrate de fexofénadine amorphe à partir de fexofénadine via son sel d'addition avec un acide faible, avec un rendement de production élevé et une pureté élevée. La présente invention concerne en outre un procédé pour la préparation de chlorhydrate de fexofénadine amorphe à partir de sel d'addition avec un acide de la fexofénadine.
PCT/IN2008/000581 2007-09-13 2008-09-11 Procédé pour la préparation de chlorhydrate de fexofénadine amorphe Ceased WO2009034582A2 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IN1951/DEL/2007 2007-09-13
IN1951DE2007 2007-09-13

Publications (2)

Publication Number Publication Date
WO2009034582A2 WO2009034582A2 (fr) 2009-03-19
WO2009034582A3 true WO2009034582A3 (fr) 2010-05-06

Family

ID=40452661

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IN2008/000581 Ceased WO2009034582A2 (fr) 2007-09-13 2008-09-11 Procédé pour la préparation de chlorhydrate de fexofénadine amorphe

Country Status (1)

Country Link
WO (1) WO2009034582A2 (fr)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20090306135A1 (en) * 2008-03-24 2009-12-10 Mukesh Kumar Sharma Stable amorphous fexofenadine hydrochloride
ES2403130B1 (es) * 2010-06-15 2014-09-29 Chemelectiva S.R.L. Forma polimórfica de clorhidrato de fexofenadina, compuestos intermedios y procedimiento para su preparación
WO2012135338A1 (fr) * 2011-03-28 2012-10-04 Ratiopharm Gmbh Procédés pour la préparation de sels de tofacitinib

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005019175A1 (fr) * 2003-08-26 2005-03-03 Cipla Limited Polymorphes de la fexofenadine et leurs procedes de preparation
WO2006037042A1 (fr) * 2004-09-28 2006-04-06 Teva Pharmaceutical Industries Ltd. Forme de cristal de fexofenadine et ses processus de preparation
WO2007007347A1 (fr) * 2005-07-07 2007-01-18 Wockhardt Limited Procédé industriel de préparation du chlorhydrate de fexofénadine avec un minimum de produits secondaires

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005019175A1 (fr) * 2003-08-26 2005-03-03 Cipla Limited Polymorphes de la fexofenadine et leurs procedes de preparation
WO2006037042A1 (fr) * 2004-09-28 2006-04-06 Teva Pharmaceutical Industries Ltd. Forme de cristal de fexofenadine et ses processus de preparation
WO2007007347A1 (fr) * 2005-07-07 2007-01-18 Wockhardt Limited Procédé industriel de préparation du chlorhydrate de fexofénadine avec un minimum de produits secondaires

Also Published As

Publication number Publication date
WO2009034582A2 (fr) 2009-03-19

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