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WO2009025364A1 - 非特異反応抑制剤 - Google Patents

非特異反応抑制剤 Download PDF

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Publication number
WO2009025364A1
WO2009025364A1 PCT/JP2008/065032 JP2008065032W WO2009025364A1 WO 2009025364 A1 WO2009025364 A1 WO 2009025364A1 JP 2008065032 W JP2008065032 W JP 2008065032W WO 2009025364 A1 WO2009025364 A1 WO 2009025364A1
Authority
WO
WIPO (PCT)
Prior art keywords
specific reaction
reaction inhibitor
immunological measurement
inhibitor
antibody
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/JP2008/065032
Other languages
English (en)
French (fr)
Inventor
Yoshikazu Takagi
Yuichi Shintani
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Mitsubishi Kagaku Iatron Inc
Original Assignee
Mitsubishi Kagaku Iatron Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mitsubishi Kagaku Iatron Inc filed Critical Mitsubishi Kagaku Iatron Inc
Priority to US12/674,410 priority Critical patent/US20110189704A1/en
Priority to KR1020107006312A priority patent/KR101491700B1/ko
Priority to CA2697656A priority patent/CA2697656C/en
Priority to EP08827899.9A priority patent/EP2184608B1/en
Priority to AU2008289857A priority patent/AU2008289857B2/en
Priority to ES08827899.9T priority patent/ES2609280T3/es
Priority to JP2009529077A priority patent/JP5189098B2/ja
Publication of WO2009025364A1 publication Critical patent/WO2009025364A1/ja
Anticipated expiration legal-status Critical
Priority to US14/526,415 priority patent/US10168325B2/en
Ceased legal-status Critical Current

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54393Improving reaction conditions or stability, e.g. by coating or irradiation of surface, by reduction of non-specific binding, by promotion of specific binding
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/5306Improving reaction conditions, e.g. reduction of non-specific binding, promotion of specific binding

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Analytical Chemistry (AREA)
  • Biotechnology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

 非特異反応因子に特異的に結合する抗体又はその断片と高分子化合物との複合体を含む、免疫学的測定用の非特異反応抑制剤を開示する。前記非特異反応抑制剤は、免疫測定法において、微量物質を正確に検出、定量する際の障害となる非特異反応を抑制することができる。
PCT/JP2008/065032 2007-08-23 2008-08-22 非特異反応抑制剤 Ceased WO2009025364A1 (ja)

Priority Applications (8)

Application Number Priority Date Filing Date Title
US12/674,410 US20110189704A1 (en) 2007-08-23 2008-08-22 Non-specific reaction inhibitor
KR1020107006312A KR101491700B1 (ko) 2007-08-23 2008-08-22 비특이반응 억제제
CA2697656A CA2697656C (en) 2007-08-23 2008-08-22 Non-specific reaction inhibitor
EP08827899.9A EP2184608B1 (en) 2007-08-23 2008-08-22 Non-specific reaction inhibitor
AU2008289857A AU2008289857B2 (en) 2007-08-23 2008-08-22 Use of non-specific reaction inhibitor
ES08827899.9T ES2609280T3 (es) 2007-08-23 2008-08-22 Inhibidor de reacción no específica
JP2009529077A JP5189098B2 (ja) 2007-08-23 2008-08-22 非特異反応抑制剤
US14/526,415 US10168325B2 (en) 2007-08-23 2014-10-28 Non-specific reaction inhibitor

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2007-216750 2007-08-23
JP2007216750 2007-08-23

Related Child Applications (2)

Application Number Title Priority Date Filing Date
US12/674,410 A-371-Of-International US20110189704A1 (en) 2007-08-23 2008-08-22 Non-specific reaction inhibitor
US14/526,415 Continuation US10168325B2 (en) 2007-08-23 2014-10-28 Non-specific reaction inhibitor

Publications (1)

Publication Number Publication Date
WO2009025364A1 true WO2009025364A1 (ja) 2009-02-26

Family

ID=40378264

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/JP2008/065032 Ceased WO2009025364A1 (ja) 2007-08-23 2008-08-22 非特異反応抑制剤

Country Status (8)

Country Link
US (2) US20110189704A1 (ja)
EP (1) EP2184608B1 (ja)
JP (1) JP5189098B2 (ja)
KR (1) KR101491700B1 (ja)
AU (1) AU2008289857B2 (ja)
CA (1) CA2697656C (ja)
ES (1) ES2609280T3 (ja)
WO (1) WO2009025364A1 (ja)

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2013118844A1 (ja) * 2012-02-07 2013-08-15 オーソ・クリニカル・ダイアグノスティックス株式会社 検出対象の検出及び定量のための方法及びキット
JP2015166750A (ja) * 2009-03-03 2015-09-24 アクセス メディカル システムズ,リミティド 高感度蛍光分析のための検出システム及び方法
JP6084759B1 (ja) * 2015-08-17 2017-02-22 積水メディカル株式会社 免疫学的検出方法及びこれに用いるテストストリップ
WO2018203572A1 (ja) * 2017-05-02 2018-11-08 田中貴金属工業株式会社 非特異反応抑制剤
WO2022163605A1 (ja) * 2021-01-26 2022-08-04 積水メディカル株式会社 免疫学的測定方法
WO2025047641A1 (ja) * 2023-08-25 2025-03-06 積水メディカル株式会社 免疫学的測定方法、免疫学的測定用試薬、免疫学的測定用検体前処理液、及び免疫学的測定用試薬キット、非特異反応抑制剤
JP7736395B1 (ja) * 2024-02-29 2025-09-09 積水メディカル株式会社 免疫学的測定方法、免疫学的測定用試薬、免疫学的測定用検体前処理液、免疫学的測定用試薬キット、及び非特異反応抑制剤

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103620407B (zh) * 2011-06-29 2016-09-21 美迪恩斯生命科技株式会社 非特异性反应抑制剂、非特异性反应抑制方法及试剂盒
CN113777312B (zh) * 2021-09-03 2024-02-02 普十生物科技(北京)有限公司 乙肝抗体片段的制备方法、乙肝抗体片段、试剂盒及应用
KR20240150777A (ko) 2022-02-18 2024-10-16 피에이치씨 주식회사 비특이 반응 억제제

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JPH11287801A (ja) * 1998-04-01 1999-10-19 Denka Seiken Co Ltd 免疫学的測定法および免疫学的測定用キット
JP2000180446A (ja) * 1998-12-11 2000-06-30 Wako Pure Chem Ind Ltd 干渉作用を回避する方法及び試薬
JP2004325414A (ja) * 2003-04-28 2004-11-18 Sekisui Chem Co Ltd 免疫測定方法及び免疫測定キット
JP3602135B2 (ja) * 1994-11-04 2004-12-15 ロシュ ダイアグノスティックス ゲーエムベーハー 抗体クラス特異的干渉除去剤

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DE3266967D1 (en) * 1982-01-05 1985-11-21 Int Inst Cellular Molecul Path Method of immunoassay
CA1291031C (en) * 1985-12-23 1991-10-22 Nikolaas C.J. De Jaeger Method for the detection of specific binding agents and their correspondingbindable substances
IL84160A0 (en) * 1986-10-16 1988-03-31 Vasocor Method and kit for immune complex assay
DE3717401A1 (de) * 1987-05-23 1988-12-08 Behringwerke Ag Einschritt-immuntest zur bestimmung von antigen-spezifischen antikoerpern aus einer der immunglobulin-klassen a, m, d oder e und dazu geeignetes mittel
US4914040A (en) * 1988-03-03 1990-04-03 Boehringer Mannheim Gmbh Reagent and method for determination of a polyvalent substance using an immunoaggregate
US5541297A (en) * 1988-04-01 1996-07-30 Immunomedics, Inc. Therapeutic conjugates of toxins and drugs
ES2193136T3 (es) * 1991-08-14 2003-11-01 Genentech Inc Variantes de inmunoglubina para receptores especificos de fc epsilon.
DE19748489A1 (de) * 1997-11-03 1999-05-06 Roche Diagnostics Gmbh Polyethylenglykol-derivatisierte Biomoleküle und deren Verwendung in heterogenen Nachweisverfahren
JP2000266746A (ja) * 1999-03-16 2000-09-29 Snow Brand Milk Prod Co Ltd 特異的IgE抗体測定方法
JP2001041958A (ja) * 1999-07-28 2001-02-16 Takeda Chem Ind Ltd 環境汚染物質の免疫学的測定分析法
EP1370588A2 (en) * 2001-02-12 2003-12-17 Medarex, Inc. Human monoclonal antibodies to fc alpha receptor (cd89)
CA2492457A1 (en) * 2002-08-02 2004-02-12 Craig A. Rosen Antibodies against c3a receptor
AU2003262650B2 (en) * 2002-08-14 2009-10-29 Macrogenics, Inc. FcgammaRIIB-specific antibodies and methods of use thereof
JP4418895B2 (ja) 2004-07-28 2010-02-24 株式会社シノテスト 非特異的反応抑制剤、非特異的反応の抑制方法、免疫学的測定方法及び免疫学的測定試薬
CA2606018A1 (en) * 2005-04-28 2006-11-02 Ventana Medical Systems, Inc. Nanoparticle conjugates
CN102246043B (zh) * 2008-12-25 2016-06-08 环球生物研究株式会社 试样的预处理方法和生物相关物质的测定方法

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3602135B2 (ja) * 1994-11-04 2004-12-15 ロシュ ダイアグノスティックス ゲーエムベーハー 抗体クラス特異的干渉除去剤
JPH11287801A (ja) * 1998-04-01 1999-10-19 Denka Seiken Co Ltd 免疫学的測定法および免疫学的測定用キット
JP2000180446A (ja) * 1998-12-11 2000-06-30 Wako Pure Chem Ind Ltd 干渉作用を回避する方法及び試薬
JP2004325414A (ja) * 2003-04-28 2004-11-18 Sekisui Chem Co Ltd 免疫測定方法及び免疫測定キット

Cited By (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2015166750A (ja) * 2009-03-03 2015-09-24 アクセス メディカル システムズ,リミティド 高感度蛍光分析のための検出システム及び方法
WO2013118844A1 (ja) * 2012-02-07 2013-08-15 オーソ・クリニカル・ダイアグノスティックス株式会社 検出対象の検出及び定量のための方法及びキット
JPWO2013118844A1 (ja) * 2012-02-07 2015-05-11 オーソ・クリニカル・ダイアグノスティックス株式会社 検出対象の検出及び定量のための方法及びキット
JP6084759B1 (ja) * 2015-08-17 2017-02-22 積水メディカル株式会社 免疫学的検出方法及びこれに用いるテストストリップ
WO2017029992A1 (ja) * 2015-08-17 2017-02-23 積水メディカル株式会社 免疫学的検出方法及びこれに用いるテストストリップ
WO2018203572A1 (ja) * 2017-05-02 2018-11-08 田中貴金属工業株式会社 非特異反応抑制剤
JPWO2018203572A1 (ja) * 2017-05-02 2020-03-12 田中貴金属工業株式会社 非特異反応抑制剤
JP7051824B2 (ja) 2017-05-02 2022-04-11 田中貴金属工業株式会社 非特異反応抑制剤
WO2022163605A1 (ja) * 2021-01-26 2022-08-04 積水メディカル株式会社 免疫学的測定方法
WO2025047641A1 (ja) * 2023-08-25 2025-03-06 積水メディカル株式会社 免疫学的測定方法、免疫学的測定用試薬、免疫学的測定用検体前処理液、及び免疫学的測定用試薬キット、非特異反応抑制剤
JP7736395B1 (ja) * 2024-02-29 2025-09-09 積水メディカル株式会社 免疫学的測定方法、免疫学的測定用試薬、免疫学的測定用検体前処理液、免疫学的測定用試薬キット、及び非特異反応抑制剤

Also Published As

Publication number Publication date
JPWO2009025364A1 (ja) 2010-11-25
KR20100076951A (ko) 2010-07-06
EP2184608A1 (en) 2010-05-12
CA2697656A1 (en) 2009-02-26
AU2008289857A2 (en) 2010-05-13
ES2609280T3 (es) 2017-04-19
US20150050666A1 (en) 2015-02-19
AU2008289857A1 (en) 2009-02-26
US10168325B2 (en) 2019-01-01
EP2184608A4 (en) 2010-11-03
KR101491700B1 (ko) 2015-02-11
US20110189704A1 (en) 2011-08-04
CA2697656C (en) 2017-10-03
AU2008289857B2 (en) 2014-06-05
EP2184608B1 (en) 2016-10-05
JP5189098B2 (ja) 2013-04-24

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