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WO2009021964A3 - Plate-forme de biopuce optique dotée d'une structure plasmonique - Google Patents

Plate-forme de biopuce optique dotée d'une structure plasmonique Download PDF

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Publication number
WO2009021964A3
WO2009021964A3 PCT/EP2008/060621 EP2008060621W WO2009021964A3 WO 2009021964 A3 WO2009021964 A3 WO 2009021964A3 EP 2008060621 W EP2008060621 W EP 2008060621W WO 2009021964 A3 WO2009021964 A3 WO 2009021964A3
Authority
WO
WIPO (PCT)
Prior art keywords
optical
operably
plasmonic
plasmonic structure
biochip platform
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/EP2008/060621
Other languages
English (en)
Other versions
WO2009021964A2 (fr
Inventor
Brian Maccraith
Michal Trnavsky
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Dublin City University
Original Assignee
Dublin City University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dublin City University filed Critical Dublin City University
Publication of WO2009021964A2 publication Critical patent/WO2009021964A2/fr
Publication of WO2009021964A3 publication Critical patent/WO2009021964A3/fr
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

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Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/645—Specially adapted constructive features of fluorimeters
    • G01N21/648—Specially adapted constructive features of fluorimeters using evanescent coupling or surface plasmon coupling for the excitation of fluorescence
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/6428—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/645—Specially adapted constructive features of fluorimeters
    • G01N21/6452—Individual samples arranged in a regular 2D-array, e.g. multiwell plates
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366—Apparatus specially adapted for solid-phase testing
    • G01N33/54373—Apparatus specially adapted for solid-phase testing involving physiochemical end-point determination, e.g. wave-guides, FETS, gratings

Landscapes

  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Optics & Photonics (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)

Abstract

La présente invention a trait à des capteurs luminescents qui sont configurés de manière à ce que des effets plasmoniques contribuent de façon opérationnelle à la sortie des capteurs. Selon un agencement préféré, la présente invention fournit un capteur doté d'un élément optique qui procède de façon opérationnelle à la génération d'un signal de luminescence pour une détection ultérieure, l'élément optique étant configuré de manière à ce que les effets plasmoniques contribuent de façon opérationnelle à la génération et/ou à la capture du signal de luminescence. L'invention a également trait à une plate-forme de biopuce optique dotée ayant une structure plasmonique destinée à détecter une fluorescence au tout autre signal luminescent et à des configurations ou à des systèmes de capteur optique qui utilisent une puce optique.
PCT/EP2008/060621 2007-08-13 2008-08-13 Plate-forme de biopuce optique dotée d'une structure plasmonique Ceased WO2009021964A2 (fr)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US95550407P 2007-08-13 2007-08-13
US60/955,504 2007-08-13
US2255908P 2008-01-22 2008-01-22
US61/022,559 2008-01-22

Publications (2)

Publication Number Publication Date
WO2009021964A2 WO2009021964A2 (fr) 2009-02-19
WO2009021964A3 true WO2009021964A3 (fr) 2009-04-16

Family

ID=40070823

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2008/060621 Ceased WO2009021964A2 (fr) 2007-08-13 2008-08-13 Plate-forme de biopuce optique dotée d'une structure plasmonique

Country Status (1)

Country Link
WO (1) WO2009021964A2 (fr)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2480293A (en) * 2010-05-12 2011-11-16 Univ Dublin City A luminescence based sensor
FR2982028B1 (fr) * 2011-10-26 2020-02-21 Aryballe Technologies Puce microstructuree comprenant des surfaces convexes pour analyse par resonance des plasmons de surface, dispositif d'analyse contenant ladite puce microstructuree et utilisation dudit dispositif
FR2982027B1 (fr) 2011-10-26 2014-01-03 Thibaut Mercey Puce microstructuree pour analyse par resonance des plasmons de surface, dispositif d'analyse comprenant ladite puce microstructuree et utilisation dudit dispositif
US20160370289A1 (en) * 2014-02-26 2016-12-22 Konica Minolta, Inc. Sensor chip for surface plasmon-field enhanced fluorescence spectroscopy
WO2016015701A1 (fr) 2014-07-31 2016-02-04 Schebo Biotech Ag Dispositif d'analyse biologique, sa fabrication et procédé de détection d'analytes biologiques au moyen du dispositif
WO2018046689A1 (fr) * 2016-09-08 2018-03-15 Danmarks Tekniske Universitet Système de puce polymère et ses utilisations
WO2024080956A1 (fr) * 2022-10-11 2024-04-18 Bilkent Universitesi Ulusal Nanoteknoloji Arastirma Merkezi Procédé d'obtention d'un dispositif utilisé dans la détection de biomarqueurs

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19651935A1 (de) * 1996-12-14 1998-06-18 Ruckstuhl Thomas Detektionssystem für den optischen Nachweis von Molekülen
US6090545A (en) * 1995-03-10 2000-07-18 Meso Scale Technologies, Llc. Multi-array, multi-specific electrochemiluminescence testing
US20040113077A1 (en) * 2002-09-25 2004-06-17 Stefan Franzen Surface plasmon resonance systems and methods having a variable charge density layer
US20050009198A1 (en) * 2001-09-11 2005-01-13 Maccraith Brian Luminescence-based sensor assembly

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6090545A (en) * 1995-03-10 2000-07-18 Meso Scale Technologies, Llc. Multi-array, multi-specific electrochemiluminescence testing
DE19651935A1 (de) * 1996-12-14 1998-06-18 Ruckstuhl Thomas Detektionssystem für den optischen Nachweis von Molekülen
US20050009198A1 (en) * 2001-09-11 2005-01-13 Maccraith Brian Luminescence-based sensor assembly
US20040113077A1 (en) * 2002-09-25 2004-06-17 Stefan Franzen Surface plasmon resonance systems and methods having a variable charge density layer

Non-Patent Citations (6)

* Cited by examiner, † Cited by third party
Title
BLUE R ET AL: "Platform for enhanced detection efficiency in luminescence-based sensors", ELECTRONICS LETTERS, IEE STEVENAGE, GB, vol. 41, no. 12, 9 June 2005 (2005-06-09), pages 682 - 684, XP006024192, ISSN: 0013-5194 *
KRIEG ET AL: "Towards single-molecule DNA sequencing: Assays with low nonspecific adsorption", ANALYTICAL BIOCHEMISTRY, ACADEMIC PRESS INC. NEW YORK, vol. 349, no. 2, 15 February 2006 (2006-02-15), pages 181 - 185, XP005274783, ISSN: 0003-2697 *
ONDREJ STRANIK ET AL: "Optimization of Nanoparticle Size for Plasmonic Enhancement of Fluorescence", PLASMONICS, KLUWER ACADEMIC PUBLISHERS-PLENUM PUBLISHERS, NE, vol. 2, no. 1, 29 December 2006 (2006-12-29), pages 15 - 22, XP019486272, ISSN: 1557-1963 *
PALUMBO M ET AL: "Surface plasmon resonance detection of metal ions: layer-by-layer assembly of polyelectrolyte sensing layers on a multichannel chip", IEEE SENSORS JOURNAL IEEE USA, vol. 5, no. 6, December 2005 (2005-12-01), pages 1159 - 1164, XP002515936, ISSN: 1530-437X, Retrieved from the Internet <URL:http://ieeexplore.ieee.org/search/wrapper.jsp?arnumber=1532253> [retrieved on 20090219] *
STRANIK ET AL: "Plasmonic enhancement of fluorescence for sensor applications", SENSORS AND ACTUATORS B, ELSEVIER SEQUOIA S.A., LAUSANNE, CH, vol. 107, no. 1, 27 May 2005 (2005-05-27), pages 148 - 153, XP005247626, ISSN: 0925-4005 *
TANG ET AL: "Enzymatically biocatalytic precipitates amplified antibody-antigen interaction for super low level immunoassay: An investigation combined surface plasmon resonance with electrochemistry", BIOSENSORS & BIOELECTRONICS, ELSEVIER SCIENCE PUBLISHERS, BARKING, GB, vol. 23, no. 5, 10 August 2007 (2007-08-10), pages 668 - 674, XP022345922, ISSN: 0956-5663 *

Also Published As

Publication number Publication date
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