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WO2009020104A1 - アデニン化合物を含有するゲル状外用組成物 - Google Patents

アデニン化合物を含有するゲル状外用組成物 Download PDF

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Publication number
WO2009020104A1
WO2009020104A1 PCT/JP2008/063982 JP2008063982W WO2009020104A1 WO 2009020104 A1 WO2009020104 A1 WO 2009020104A1 JP 2008063982 W JP2008063982 W JP 2008063982W WO 2009020104 A1 WO2009020104 A1 WO 2009020104A1
Authority
WO
WIPO (PCT)
Prior art keywords
composition
external application
gel
adenine
adenosine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/JP2008/063982
Other languages
English (en)
French (fr)
Inventor
Misato Nakajo
Fumiki Harano
Kosaburo Wakamatsu
Kazuhiro Yagyu
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Otsuka Pharmaceutical Co Ltd
Kanae Technos Co Ltd
Original Assignee
Otsuka Pharmaceutical Co Ltd
Kanae Technos Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Otsuka Pharmaceutical Co Ltd, Kanae Technos Co Ltd filed Critical Otsuka Pharmaceutical Co Ltd
Priority to EP08792179.7A priority Critical patent/EP2174647B1/en
Priority to CA2694061A priority patent/CA2694061C/en
Priority to JP2009526455A priority patent/JP5791227B2/ja
Priority to ES08792179.7T priority patent/ES2657403T3/es
Priority to US12/672,254 priority patent/US9597266B2/en
Priority to HK10110095.1A priority patent/HK1143698B/xx
Priority to AU2008284807A priority patent/AU2008284807B2/en
Priority to CN2008801016283A priority patent/CN101778619B/zh
Publication of WO2009020104A1 publication Critical patent/WO2009020104A1/ja
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
    • A61K8/0208—Tissues; Wipes; Patches
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
    • A61K31/52—Purines, e.g. adenine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
    • A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
    • A61K31/7076—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines containing purines, e.g. adenosine, adenylic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
    • A61K8/0212—Face masks
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/60—Sugars; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/60—Sugars; Derivatives thereof
    • A61K8/606—Nucleosides; Nucleotides; Nucleic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7007—Drug-containing films, membranes or sheets
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/16—Emollients or protectives, e.g. against radiation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin
    • A61Q19/08—Anti-ageing preparations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/80—Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
    • A61K2800/88—Two- or multipart kits
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A61K47/183—Amino acids, e.g. glycine, EDTA or aspartame

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Birds (AREA)
  • Dermatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Inorganic Chemistry (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • Gerontology & Geriatric Medicine (AREA)
  • Toxicology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Cosmetics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)

Abstract

　本発明の目的は、皮膚の一部分に適用されることにより、アデニン、アデノシン、及びアデノシンのリン酸エステル等のアデニン化合物の持つ有用作用をより有効に導き出し、更には持続性に優れ、皮膚の保湿効果をも高めることができる外用組成物を提供することである。 　寒天をゲル化剤として使用して、アデニン、アデノシン、及びアデノシンのリン酸エステル等のアデニン化合物を含有するゲル状外用組成物を調製する。更に、当該ゲル状外用組成物をシート状の貼付剤の形態にする。また、シート状の貼付剤形態である上記ゲル状外用組成物を、上記アデニン化合物を含む水溶液に浸漬された状態で収容しておく。
PCT/JP2008/063982 2007-08-06 2008-08-04 アデニン化合物を含有するゲル状外用組成物 Ceased WO2009020104A1 (ja)

Priority Applications (8)

Application Number Priority Date Filing Date Title
EP08792179.7A EP2174647B1 (en) 2007-08-06 2008-08-04 Gel composition for external application containing an adenine compound
CA2694061A CA2694061C (en) 2007-08-06 2008-08-04 Gel composition for external application containing an adenine compound
JP2009526455A JP5791227B2 (ja) 2007-08-06 2008-08-04 アデニン化合物を含有するゲル状外用組成物
ES08792179.7T ES2657403T3 (es) 2007-08-06 2008-08-04 Composición de gel para aplicación externa que contiene un compuesto de adenina
US12/672,254 US9597266B2 (en) 2007-08-06 2008-08-04 Gel composition for external application containing an adenine compound
HK10110095.1A HK1143698B (en) 2007-08-06 2008-08-04 Gel-like composition for external application comprising adenine compound
AU2008284807A AU2008284807B2 (en) 2007-08-06 2008-08-04 Gel composition for external application containing an adenine compound
CN2008801016283A CN101778619B (zh) 2007-08-06 2008-08-04 含有腺嘌呤化合物的凝胶状外用组合物

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2007-204556 2007-08-06
JP2007204556 2007-08-06

Publications (1)

Publication Number Publication Date
WO2009020104A1 true WO2009020104A1 (ja) 2009-02-12

Family

ID=40341336

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/JP2008/063982 Ceased WO2009020104A1 (ja) 2007-08-06 2008-08-04 アデニン化合物を含有するゲル状外用組成物

Country Status (10)

Country Link
US (1) US9597266B2 (ja)
EP (1) EP2174647B1 (ja)
JP (2) JP5791227B2 (ja)
KR (1) KR101604778B1 (ja)
CN (1) CN101778619B (ja)
AU (1) AU2008284807B2 (ja)
CA (1) CA2694061C (ja)
ES (1) ES2657403T3 (ja)
TW (1) TWI435734B (ja)
WO (1) WO2009020104A1 (ja)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2012017911A1 (ja) * 2010-08-03 2012-02-09 株式会社林原生物化学研究所 美白強化剤とその用途
JP2012530683A (ja) * 2009-06-19 2012-12-06 大塚製薬株式会社 皮膚水分透過機能異常の予防又は治療剤
JP2017009489A (ja) * 2015-06-24 2017-01-12 花王株式会社 皮膚の触覚測定方法および化粧料の性能評価方法

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK2465581T3 (da) * 2010-12-15 2020-04-06 Energenesis Biomedical Co Ltd Ikke-terapeutisk anvendelse af en sammensætning til fremme af hårvækst
JP6389308B1 (ja) * 2017-08-23 2018-09-12 一丸ファルコス株式会社 皮膚外用剤
CN116634925A (zh) 2020-08-03 2023-08-22 强生消费者公司 选择性施用化妆品组合物以赋予眼下亮白的系统和方法

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2002234830A (ja) 2000-11-22 2002-08-23 Otsuka Pharmaceut Co Ltd Ｏ／ｗ型乳化組成物及びその調製方法
JP2003063924A (ja) * 2001-08-24 2003-03-05 Toshin Kagaku Kk フィルム状皮膚外用剤
JP2003334212A (ja) * 2002-05-20 2003-11-25 Maikooru Kk 美顔用発熱体
JP2006056543A (ja) * 2004-08-18 2006-03-02 Kanae Technos:Kk パック用ゲルシート包装体
JP2006182746A (ja) 2004-12-28 2006-07-13 Otsuka Pharmaceut Co Ltd 水中油型エマルジョンからなる固形組成物

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Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2002234830A (ja) 2000-11-22 2002-08-23 Otsuka Pharmaceut Co Ltd Ｏ／ｗ型乳化組成物及びその調製方法
JP2003063924A (ja) * 2001-08-24 2003-03-05 Toshin Kagaku Kk フィルム状皮膚外用剤
JP2003334212A (ja) * 2002-05-20 2003-11-25 Maikooru Kk 美顔用発熱体
JP2006056543A (ja) * 2004-08-18 2006-03-02 Kanae Technos:Kk パック用ゲルシート包装体
JP2006182746A (ja) 2004-12-28 2006-07-13 Otsuka Pharmaceut Co Ltd 水中油型エマルジョンからなる固形組成物

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2012530683A (ja) * 2009-06-19 2012-12-06 大塚製薬株式会社 皮膚水分透過機能異常の予防又は治療剤
WO2012017911A1 (ja) * 2010-08-03 2012-02-09 株式会社林原生物化学研究所 美白強化剤とその用途
JPWO2012017911A1 (ja) * 2010-08-03 2013-10-03 株式会社林原 美白強化剤とその用途
JP2017009489A (ja) * 2015-06-24 2017-01-12 花王株式会社 皮膚の触覚測定方法および化粧料の性能評価方法

Also Published As

Publication number Publication date
AU2008284807A1 (en) 2009-02-12
JP5791227B2 (ja) 2015-10-07
AU2008284807B2 (en) 2013-03-14
CA2694061C (en) 2015-11-03
CN101778619A (zh) 2010-07-14
CA2694061A1 (en) 2009-02-12
US20110224163A1 (en) 2011-09-15
EP2174647A4 (en) 2015-07-22
KR20100040723A (ko) 2010-04-20
CN101778619B (zh) 2012-05-23
KR101604778B1 (ko) 2016-03-18
TW200914059A (en) 2009-04-01
TWI435734B (zh) 2014-05-01
EP2174647A1 (en) 2010-04-14
US9597266B2 (en) 2017-03-21
EP2174647B1 (en) 2017-12-13
JPWO2009020104A1 (ja) 2010-11-04
JP2015157874A (ja) 2015-09-03
ES2657403T3 (es) 2018-03-05
JP6486773B2 (ja) 2019-03-20
HK1143698A1 (en) 2011-01-07

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