[go: up one dir, main page]

WO2009016608A3 - Compositions pharmaceutiques de fénofibrate - Google Patents

Compositions pharmaceutiques de fénofibrate Download PDF

Info

Publication number
WO2009016608A3
WO2009016608A3 PCT/IB2008/053091 IB2008053091W WO2009016608A3 WO 2009016608 A3 WO2009016608 A3 WO 2009016608A3 IB 2008053091 W IB2008053091 W IB 2008053091W WO 2009016608 A3 WO2009016608 A3 WO 2009016608A3
Authority
WO
WIPO (PCT)
Prior art keywords
pharmaceutical compositions
fenofibrate
relates
compositions
micronized fenofibrate
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/IB2008/053091
Other languages
English (en)
Other versions
WO2009016608A2 (fr
Inventor
Rahul Dabre
Roshanlal Sandal
Vikrant Thakkar
Girish Kumar Jain
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wockhardt Research Centre
Original Assignee
Wockhardt Research Centre
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wockhardt Research Centre filed Critical Wockhardt Research Centre
Priority to EP08789518A priority Critical patent/EP2190415A2/fr
Priority to US12/671,832 priority patent/US20100285126A1/en
Publication of WO2009016608A2 publication Critical patent/WO2009016608A2/fr
Publication of WO2009016608A3 publication Critical patent/WO2009016608A3/fr
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/216—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acids having aromatic rings, e.g. benactizyne, clofibrate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2059—Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2095—Tabletting processes; Dosage units made by direct compression of powders or specially processed granules, by eliminating solvents, by melt-extrusion, by injection molding, by 3D printing

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Emergency Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)

Abstract

L'invention porte sur des compositions pharmaceutiques comprenant du fénofibrate non micronisé avec un ou plusieurs véhicules pharmaceutiquement acceptables. L'invention porte également sur des compositions pharmaceutiques comprenant du fénofibrate non micronisé avec un ou plusieurs dérivés de cyclodextrine. L'invention porte également sur des procédés pour la préparation de telles compositions.
PCT/IB2008/053091 2007-08-02 2008-08-01 Compositions pharmaceutiques de fénofibrate Ceased WO2009016608A2 (fr)

Priority Applications (2)

Application Number Priority Date Filing Date Title
EP08789518A EP2190415A2 (fr) 2007-08-02 2008-08-01 Compositions pharmaceutiques de fénofibrate
US12/671,832 US20100285126A1 (en) 2007-08-02 2008-08-01 Pharmaceutical compositions of fenofibrate

Applications Claiming Priority (12)

Application Number Priority Date Filing Date Title
IN1488MU2007 2007-08-02
IN1484MU2007 2007-08-02
IN1486MU2007 2007-08-02
IN1487/MUM/2007 2007-08-02
IN1488/MUM/2007 2007-08-02
IN1485MU2007 2007-08-02
IN1484/MUM/2007 2007-08-02
IN1486/MUM/2007 2007-08-02
IN1485/MUM/2007 2007-08-02
IN1487MU2007 2007-08-02
IN600/MUM/2008 2008-03-24
IN600MU2008 2008-03-24

Publications (2)

Publication Number Publication Date
WO2009016608A2 WO2009016608A2 (fr) 2009-02-05
WO2009016608A3 true WO2009016608A3 (fr) 2009-05-28

Family

ID=40174794

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IB2008/053091 Ceased WO2009016608A2 (fr) 2007-08-02 2008-08-01 Compositions pharmaceutiques de fénofibrate

Country Status (2)

Country Link
EP (1) EP2190415A2 (fr)
WO (1) WO2009016608A2 (fr)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2865371B1 (fr) * 2013-10-22 2016-08-10 Disphar International B.V. Granules à dissolution rapide
WO2017145356A1 (fr) 2016-02-26 2017-08-31 株式会社ニコン Dispositif de détection, système de détection, procédé de détection, dispositif de traitement d'informations, et programme de traitement
CN107126420A (zh) * 2017-05-09 2017-09-05 上海信谊万象药业股份有限公司 一种高溶出度非诺贝特片及其制备方法
CN107469091B (zh) * 2017-07-25 2020-09-22 广东省药品检验所（广东省药品质量研究所、广东省口岸药品检验所） 一种磁性非诺贝特-环糊精包合物

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004002414A2 (fr) * 2002-06-28 2004-01-08 Shire Laboratories Inc. Preparation auto emulsifiantes de fenofibrate et/ou de derives de fenofibrate avec liberation des caracteristiques biologiques amelioree et/ou effet alimentaire reduit
US20040157797A1 (en) * 2003-02-03 2004-08-12 Rong-Kun Chang Drug formulation and delivery using crystalline methylated cyclodextrins
WO2005034920A1 (fr) * 2003-10-10 2005-04-21 Lifecycle Pharma A/S Forme de dose solide comprenant un fibrate
US20050096391A1 (en) * 2003-10-10 2005-05-05 Per Holm Compositions comprising fenofibrate and rosuvastatin
WO2006037348A1 (fr) * 2004-10-01 2006-04-13 Lifecycle Pharma A/S Compositions pharmaceutiques contenant du fenofibrate et une statine
EP1707197A1 (fr) * 2005-03-30 2006-10-04 Teva Pharmaceutical Industries Ltd. Compositions, contenant du fenofibrate et un mélange d'agents tensio-actifs

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004002414A2 (fr) * 2002-06-28 2004-01-08 Shire Laboratories Inc. Preparation auto emulsifiantes de fenofibrate et/ou de derives de fenofibrate avec liberation des caracteristiques biologiques amelioree et/ou effet alimentaire reduit
US20040005339A1 (en) * 2002-06-28 2004-01-08 Shojaei Amir H. Formulations of fenofibrate and/or fenofibrate derivatives with improved oral bioavailability
US20040157797A1 (en) * 2003-02-03 2004-08-12 Rong-Kun Chang Drug formulation and delivery using crystalline methylated cyclodextrins
WO2005034920A1 (fr) * 2003-10-10 2005-04-21 Lifecycle Pharma A/S Forme de dose solide comprenant un fibrate
US20050096391A1 (en) * 2003-10-10 2005-05-05 Per Holm Compositions comprising fenofibrate and rosuvastatin
WO2006037348A1 (fr) * 2004-10-01 2006-04-13 Lifecycle Pharma A/S Compositions pharmaceutiques contenant du fenofibrate et une statine
EP1707197A1 (fr) * 2005-03-30 2006-10-04 Teva Pharmaceutical Industries Ltd. Compositions, contenant du fenofibrate et un mélange d'agents tensio-actifs

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
AIGNER Z ET AL: "INCREASING THE SOLUBILITY CHARACTERISTICS OF FENOFIBRATE WITH CYCLODEXTRIN", JOURNAL OF INCLUSION PHENOMENA AND MOLECULAR RECOGNITION INCHEMISTRY, KLUWER, DORDRECHT, NL, vol. 20, 1 January 1995 (1995-01-01), pages 241 - 252, XP009041938, ISSN: 0923-0750 *
PALMIERI G F ET AL: "INCLUSION COMPLEXATION OF FENOFIBRATE WITH BETA-CYCLODEXTRIN AND HYDROXYPROPYL-BETA-CYCLODEXTRIN. EVALUATION OF INTERACTIONS IN SOLUTION AND SOLID COMPLEX CHARACTERIZATION", SCIENCES TECHNIQUES ET PRATIQUES STP PHARMA SCIENCES, PARIS, FR, vol. 7, no. 2, 1 January 1997 (1997-01-01), pages 174 - 181, XP009041885, ISSN: 1157-1489 *
SHEU ET AL: "Characterization and dissolution of fenofibrate solid dispersion systems", INTERNATIONAL JOURNAL OF PHARMACEUTICS, ELSEVIER BV, NL, vol. 103, no. 2, 1 January 1994 (1994-01-01), pages 137 - 146, XP002091325, ISSN: 0378-5173 *

Also Published As

Publication number Publication date
EP2190415A2 (fr) 2010-06-02
WO2009016608A2 (fr) 2009-02-05

Similar Documents

Publication Publication Date Title
WO2011077043A3 (fr) Derives phenoliques, et leur utilisation pharmaceutique ou cosmetique
WO2007109605A3 (fr) Compositions pharmaceutiques
WO2008021368A3 (fr) Compositions et méthodes de neuroprotection
WO2007135527A3 (fr) Composés de benzimidazolyle
WO2011069063A3 (fr) Composés multicycliques et leurs procédés d'utilisation
WO2007086001A3 (fr) Nouveaux dérivés de pyridine
AU2013257508A1 (en) Pharmaceutical compositions
WO2008049116A3 (fr) Indoles substitués
AU2007299727A8 (en) Self preserved aqueous pharmaceutical compositions
WO2009121039A3 (fr) Administration de compositions de benzodiazépine
WO2009091898A3 (fr) Composés de 6-aminoisoquinoléine et 7-aminoisoquinoléine et leurs procédés de fabrication et d'utilisation
WO2007139871A3 (fr) Méthodes et matières pour l'élaboration de simvastatine et de ses composés
WO2010049454A3 (fr) Composition antimicrobienne tirée de copépodes
WO2008070268A3 (fr) Compositions pharmaceutiques
WO2008017346A3 (fr) Utilisation de dérivés d'acide ascorbique pour la fonctionnalisation de matrices
WO2009115084A3 (fr) Nouveaux dérivés de pyrrolopyrimidine et leurs utilisations
WO2008129501A3 (fr) Compositions pharmaceutiques de duloxetine
WO2008001201A3 (fr) Compositions pharmaceutiques de clopidogrel
WO2008088779A3 (fr) Formes solides de 5-azacytidine et procédés de préparation de ces dernières
WO2009118589A3 (fr) Compositions orodispersibles de rhéine ou de diacéréine
WO2011135580A3 (fr) Compositions pharmaceutiques de sirolimus
WO2010046061A3 (fr) Préparations cosmétiques et/ou pharmaceutiques
WO2008154234A3 (fr) Formulation à libération prolongée de névirapine
WO2009047794A3 (fr) Composition à base de dérivés taxanes
WO2008137134A3 (fr) Bromhydrate d'élétriptan amorphe et son procédé de préparation, et autres formes de bromhydrate d'élétriptan

Legal Events

Date Code Title Description
NENP Non-entry into the national phase

Ref country code: DE

WWE Wipo information: entry into national phase

Ref document number: 2008789518

Country of ref document: EP

WWE Wipo information: entry into national phase

Ref document number: 12671832

Country of ref document: US