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WO2009006638A3 - Peptides facilitating retrograde transport and their uses - Google Patents

Peptides facilitating retrograde transport and their uses Download PDF

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Publication number
WO2009006638A3
WO2009006638A3 PCT/US2008/069365 US2008069365W WO2009006638A3 WO 2009006638 A3 WO2009006638 A3 WO 2009006638A3 US 2008069365 W US2008069365 W US 2008069365W WO 2009006638 A3 WO2009006638 A3 WO 2009006638A3
Authority
WO
WIPO (PCT)
Prior art keywords
peptides
retrograde transport
facilitating retrograde
seq
peptides facilitating
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/US2008/069365
Other languages
French (fr)
Other versions
WO2009006638A2 (en
Inventor
Elaine L Bearer
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Dart Neuroscience LLC
Original Assignee
Dart Neuroscience LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dart Neuroscience LLC filed Critical Dart Neuroscience LLC
Priority to CA 2692603 priority Critical patent/CA2692603A1/en
Priority to AU2008272810A priority patent/AU2008272810A1/en
Priority to EP08772440A priority patent/EP2170929A2/en
Publication of WO2009006638A2 publication Critical patent/WO2009006638A2/en
Publication of WO2009006638A3 publication Critical patent/WO2009006638A3/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/71—Receptors; Cell surface antigens; Cell surface determinants for growth factors; for growth regulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Immunology (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Cell Biology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)

Abstract

The present invention concerns peptides facilitating retrograde transport and their uses. In particular, the invention concerns the peptides of KlP VIE NPQ YFG ITN (SEQ ID NO: 1) and KRE LGE GAF GKV FLA (SEQ ID NO: 2).
PCT/US2008/069365 2007-07-05 2008-07-07 Peptides facilitating retrograde transport and their uses Ceased WO2009006638A2 (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
CA 2692603 CA2692603A1 (en) 2007-07-05 2008-07-07 Peptides facilitating retrograde transport and their uses
AU2008272810A AU2008272810A1 (en) 2007-07-05 2008-07-07 Peptides facilitating retrograde transport and their uses
EP08772440A EP2170929A2 (en) 2007-07-05 2008-07-07 Peptides facilitating retrograde transport and their uses

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US94813007P 2007-07-05 2007-07-05
US60/948,130 2007-07-05

Publications (2)

Publication Number Publication Date
WO2009006638A2 WO2009006638A2 (en) 2009-01-08
WO2009006638A3 true WO2009006638A3 (en) 2009-02-26

Family

ID=40226829

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2008/069365 Ceased WO2009006638A2 (en) 2007-07-05 2008-07-07 Peptides facilitating retrograde transport and their uses

Country Status (4)

Country Link
EP (1) EP2170929A2 (en)
AU (1) AU2008272810A1 (en)
CA (1) CA2692603A1 (en)
WO (1) WO2009006638A2 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9056892B2 (en) 2011-09-09 2015-06-16 University Of Washington Retrograde transport peptide and use of same for delivery to central nervous system

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20060239988A1 (en) * 2003-06-09 2006-10-26 Michael Fainzilber Neuronal regeneration and compound administration methods

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20060239988A1 (en) * 2003-06-09 2006-10-26 Michael Fainzilber Neuronal regeneration and compound administration methods

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
JULLIEN, J. ET AL.: "Trafficking of TrkA-green Fluorescent Protein Chimerae during Nerve Growth Factor-induced Differentiation.", J. BIOL. CHEM., vol. 278, no. 10, 2003, pages 8706 - 8716, XP002441154 *
UBHATTACHARYYA A. ET AL.: "Trk Receptors Function As Rapid Retrograde Signal Carriers in the Adult Nnervous System", J. NEUROSCI., vol. 17, no. 18, 1997, pages 7007 - 7016, XP008129452 *
ZENG, J. ET AL.: "A synthetic peptidecontaining loop 4 of nerve growth factor for targeted gene delivery.", J. GEN. MED., vol. 6, 2004, pages 1247 - 1256, XP008129453 *

Also Published As

Publication number Publication date
CA2692603A1 (en) 2009-01-08
WO2009006638A2 (en) 2009-01-08
AU2008272810A1 (en) 2009-01-08
EP2170929A2 (en) 2010-04-07

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Free format text: PEDIDO RETIRADO, UMA VEZ QUE, SEGUNDO O ART. 216 INCISO 2O DA LPI, O DOCUMENTO DE PROCURACAO NAO FOI PROTOCOLADO EM SESSENTA DIAS CONTADOS DA PRATICA DO PRIMEIRO ATO DA PARTE NO PROCESSO, E NAO HOUVE MANIFESTACAO DO REQUERENTE FRENTE A PUBLICACAO DO ARQUIVAMENTO DA PETICAO (11.6.1) NA RPI 2298 DE 21/01/2015.