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WO2009005647A3 - Compounds and process to prepare chiral intermediates for synthesis of paroxetine - Google Patents

Compounds and process to prepare chiral intermediates for synthesis of paroxetine Download PDF

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Publication number
WO2009005647A3
WO2009005647A3 PCT/US2008/007870 US2008007870W WO2009005647A3 WO 2009005647 A3 WO2009005647 A3 WO 2009005647A3 US 2008007870 W US2008007870 W US 2008007870W WO 2009005647 A3 WO2009005647 A3 WO 2009005647A3
Authority
WO
WIPO (PCT)
Prior art keywords
paroxetine
compounds
synthesis
chiral intermediates
prepare chiral
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/US2008/007870
Other languages
French (fr)
Other versions
WO2009005647A2 (en
Inventor
Robert William Scott
Sean Timothy Neville
Lishan Zhao
Ningqing Ran
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
BIOVERDANT Inc
Original Assignee
BIOVERDANT Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by BIOVERDANT Inc filed Critical BIOVERDANT Inc
Publication of WO2009005647A2 publication Critical patent/WO2009005647A2/en
Publication of WO2009005647A3 publication Critical patent/WO2009005647A3/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

Provided herein are compounds and processes that produce intermediates and precursors of paroxetine and related compounds. Also provided are processes for the preparation of paroxetine.
PCT/US2008/007870 2007-06-27 2008-06-24 Compounds and process to prepare chiral intermediates for synthesis of paroxetine Ceased WO2009005647A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US93746607P 2007-06-27 2007-06-27
US60/937,466 2007-06-27

Publications (2)

Publication Number Publication Date
WO2009005647A2 WO2009005647A2 (en) 2009-01-08
WO2009005647A3 true WO2009005647A3 (en) 2009-04-09

Family

ID=40076855

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2008/007870 Ceased WO2009005647A2 (en) 2007-06-27 2008-06-24 Compounds and process to prepare chiral intermediates for synthesis of paroxetine

Country Status (1)

Country Link
WO (1) WO2009005647A2 (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11986006B2 (en) 2018-08-31 2024-05-21 Mars, Incorporated Anthocyanin-based colorant compositions and methods of use thereof

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Publication number Priority date Publication date Assignee Title
AU2011268698B2 (en) 2010-06-22 2015-03-05 Sun Pharmaceutical Industries (Australia) Pty Ltd Methyltransferase nucleic acids and polypeptides
WO2012010872A2 (en) 2010-07-22 2012-01-26 Glaxosmithkline Australia Pty Limited Plant cytochrome p450
GB201204407D0 (en) 2012-03-13 2012-04-25 Glaxosmithkline Australia Pty Ltd Nucleic acid molecule
CN104262255A (en) * 2014-09-22 2015-01-07 四川大学 Method for asymmetric catalytic synthesis of gamma-nitropyrazole amide compound
CN104892491B (en) * 2015-05-06 2017-05-17 浙江海森药业有限公司 Method for synthesizing paroxetine chiral intermediate
CN105400758A (en) * 2015-11-26 2016-03-16 青岛康原药业有限公司 Method for purifying pancreatic kininogenase through synergism of sodium chloride-ammonia water and acetone and medicine composition for improving stability of pancreatic kininogenase
AU2020357887A1 (en) * 2019-10-01 2022-04-07 Mars, Incorporated Enzymatic treatment of anthocyanins
CN114214375B (en) * 2021-12-27 2024-03-19 江苏威凯尔医药科技有限公司 Preparation method of (R)-3-(4-halo-1H-pyrazol-1-yl)-3-cyclopentylpropionate
AU2023272468A1 (en) 2022-05-14 2024-11-14 Novonesis Plant Biosolutions A/S Compositions and methods for preventing, treating, supressing and/or eliminating phytopathogenic infestations and infections

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1993022284A1 (en) * 1992-05-06 1993-11-11 Smithkline Beecham Plc Process for stereospecific hydrolysis of piperidinedione derivatives

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1993022284A1 (en) * 1992-05-06 1993-11-11 Smithkline Beecham Plc Process for stereospecific hydrolysis of piperidinedione derivatives

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
D. A. GREENHALGH ET AL.: "A Novel Chiral Base Mediated Glutarimide Desymmetrisation: Application to the Asymmetric Synthesis of (-)-Paroxetine", SYNLETT, no. 12, 2 December 2002 (2002-12-02), GEORG THIEME VERLAG, STUTTGART; DE, pages 2074 - 2076, XP002513234, ISSN: 0936-5214 *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US11986006B2 (en) 2018-08-31 2024-05-21 Mars, Incorporated Anthocyanin-based colorant compositions and methods of use thereof

Also Published As

Publication number Publication date
WO2009005647A2 (en) 2009-01-08

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