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WO2009090651A3 - Ligands des molécules hla-b2705 du complexe majeur d'histocompatibilité, utilisés à des fins de diagnostic et de traitement - Google Patents

Ligands des molécules hla-b2705 du complexe majeur d'histocompatibilité, utilisés à des fins de diagnostic et de traitement Download PDF

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Publication number
WO2009090651A3
WO2009090651A3 PCT/IL2009/000067 IL2009000067W WO2009090651A3 WO 2009090651 A3 WO2009090651 A3 WO 2009090651A3 IL 2009000067 W IL2009000067 W IL 2009000067W WO 2009090651 A3 WO2009090651 A3 WO 2009090651A3
Authority
WO
WIPO (PCT)
Prior art keywords
diagnosis
therapy
major histocompatibility
histocompatibility complex
ligands useful
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/IL2009/000067
Other languages
English (en)
Other versions
WO2009090651A2 (fr
Inventor
Lilach Halevi
Arie Admon
Eilon Barnea
Ilan Beer
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Technion Research and Development Foundation Ltd
Original Assignee
Technion Research and Development Foundation Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Technion Research and Development Foundation Ltd filed Critical Technion Research and Development Foundation Ltd
Publication of WO2009090651A2 publication Critical patent/WO2009090651A2/fr
Publication of WO2009090651A3 publication Critical patent/WO2009090651A3/fr
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70503—Immunoglobulin superfamily
    • C07K14/70539—MHC-molecules, e.g. HLA-molecules
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Cell Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Cette invention concerne des complexes HLA-B2705-peptide multimères, et leur utilisation dans le diagnostic et le traitement du cancer et d'autres troubles autoimmuns.
PCT/IL2009/000067 2008-01-15 2009-01-15 Ligands des molécules hla-b2705 du complexe majeur d'histocompatibilité, utilisés à des fins de diagnostic et de traitement Ceased WO2009090651A2 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US2105108P 2008-01-15 2008-01-15
US61/021,051 2008-01-15

Publications (2)

Publication Number Publication Date
WO2009090651A2 WO2009090651A2 (fr) 2009-07-23
WO2009090651A3 true WO2009090651A3 (fr) 2009-12-03

Family

ID=40885729

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IL2009/000067 Ceased WO2009090651A2 (fr) 2008-01-15 2009-01-15 Ligands des molécules hla-b2705 du complexe majeur d'histocompatibilité, utilisés à des fins de diagnostic et de traitement

Country Status (1)

Country Link
WO (1) WO2009090651A2 (fr)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8168181B2 (en) 2006-02-13 2012-05-01 Alethia Biotherapeutics, Inc. Methods of impairing osteoclast differentiation using antibodies that bind siglec-15
EP1994155B2 (fr) 2006-02-13 2022-05-04 Daiichi Sankyo Company, Limited Séquences polynucléotidiques et polypeptidiques intervenant dans le processus de remodelage osseux
US9289465B2 (en) * 2009-09-03 2016-03-22 Toray Industries, Inc. Immunity-inducing agent
US8946379B2 (en) * 2009-09-24 2015-02-03 The Regents Of The University Of California Bladder cancer specific ligand peptides
US9334306B2 (en) * 2011-07-09 2016-05-10 The Regents Of The University Of California Leukemia stem cell targeting ligands and methods of use
KR20150036274A (ko) 2012-07-19 2015-04-07 알레시아 바이오쎄라퓨틱스 인코포레이티드 항-siglec-15 항체
US20170232084A1 (en) 2013-04-26 2017-08-17 Enzo Biochem Inc. Immune modulation for the treatment of age-related macular degeneration
US20140322188A1 (en) * 2013-04-26 2014-10-30 Enzo Biochem, Inc. Tolerizing treatments for autoimmune disease
NL2014935B1 (en) 2015-06-08 2017-02-03 Applied Immune Tech Ltd T cell receptor like antibodies having fine specificity.
PL3424518T3 (pl) * 2016-03-02 2022-01-03 Toray Industries, Inc. Induktor odpowiedzi immunologicznej
JP2021531750A (ja) 2018-07-12 2021-11-25 ボード オブ リージェンツ, ザ ユニバーシティ オブ テキサス システムBoard Of Regents, The University Of Texas System オリゴヌクレオチドによる分子近傍検出
JP2021534394A (ja) * 2018-08-14 2021-12-09 ボード オブ リージェンツ, ザ ユニバーシティ オブ テキサス システムBoard Of Regents, The University Of Texas System 主要組織適合遺伝子複合体に結合されたペプチドを配列決定する単一分子
GB202217153D0 (en) * 2022-11-16 2022-12-28 Carocell Bio Ltd Peptides

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998012221A1 (fr) * 1996-09-18 1998-03-26 Gerhild Wildner Peptides servant d'agent diagnostique et d'agent therapeutique pour les maladies auto-immunes
WO1999058557A2 (fr) * 1998-05-11 1999-11-18 Isis Innovation Limited Nouvelle molecule et methode diagnostique
US20050053918A1 (en) * 2001-05-16 2005-03-10 Technion Research & Development Foundation Ltd. Method of identifying peptides capable of binding to MHC molecules, peptides identified thereby and their uses

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998012221A1 (fr) * 1996-09-18 1998-03-26 Gerhild Wildner Peptides servant d'agent diagnostique et d'agent therapeutique pour les maladies auto-immunes
WO1999058557A2 (fr) * 1998-05-11 1999-11-18 Isis Innovation Limited Nouvelle molecule et methode diagnostique
US20050053918A1 (en) * 2001-05-16 2005-03-10 Technion Research & Development Foundation Ltd. Method of identifying peptides capable of binding to MHC molecules, peptides identified thereby and their uses

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
GIQUEL BENOIT ET AL: "Two HLA-B27 alleles differently associated with spondylarthritis, B*2709 and B*2705, display similar intracellular trafficking and oligomer formation", ARTHRITIS & RHEUMATISM, vol. 56, no. 7, July 2007 (2007-07-01), pages 2232 - 2243, XP002547408, ISSN: 0004-3591 *

Also Published As

Publication number Publication date
WO2009090651A2 (fr) 2009-07-23

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