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WO2009071301A3 - Procédé permettant de détecter des effecteurs de l'activité protéase de cis/trans isomérases - Google Patents

Procédé permettant de détecter des effecteurs de l'activité protéase de cis/trans isomérases Download PDF

Info

Publication number
WO2009071301A3
WO2009071301A3 PCT/EP2008/010303 EP2008010303W WO2009071301A3 WO 2009071301 A3 WO2009071301 A3 WO 2009071301A3 EP 2008010303 W EP2008010303 W EP 2008010303W WO 2009071301 A3 WO2009071301 A3 WO 2009071301A3
Authority
WO
WIPO (PCT)
Prior art keywords
cis
trans
effectors
finding
isomerases
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/EP2008/010303
Other languages
German (de)
English (en)
Other versions
WO2009071301A2 (fr
Inventor
Gunter Fischer
Cordula Schiene-Fischer
Tobias Aumueller
Guenther Jahreis
Gerhard Kuellertz
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Max Planck Gesellschaft zur Foerderung der Wissenschaften
Original Assignee
Max Planck Gesellschaft zur Foerderung der Wissenschaften
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Max Planck Gesellschaft zur Foerderung der Wissenschaften filed Critical Max Planck Gesellschaft zur Foerderung der Wissenschaften
Priority to CA2708021A priority Critical patent/CA2708021A1/fr
Publication of WO2009071301A2 publication Critical patent/WO2009071301A2/fr
Publication of WO2009071301A3 publication Critical patent/WO2009071301A3/fr
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/34—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
    • C12Q1/37—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase involving peptidase or proteinase
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/533—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving isomerase
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2500/00—Screening for compounds of potential therapeutic value
    • G01N2500/20—Screening for compounds of potential therapeutic value cell-free systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Physics & Mathematics (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

L'invention concerne un procédé permettant de détecter des effecteurs de cis/trans isomérases et de quantifier l'effet inhibiteur ou activateur de cis/trans isomérases d'effecteurs correspondants.
PCT/EP2008/010303 2007-12-04 2008-12-04 Procédé permettant de détecter des effecteurs de l'activité protéase de cis/trans isomérases Ceased WO2009071301A2 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CA2708021A CA2708021A1 (fr) 2007-12-04 2008-12-04 Procede permettant de detecter des effecteurs de l'activite protease de cis/trans isomerases

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE102007058181 2007-12-04
DE102007058181.7 2007-12-04

Publications (2)

Publication Number Publication Date
WO2009071301A2 WO2009071301A2 (fr) 2009-06-11
WO2009071301A3 true WO2009071301A3 (fr) 2009-08-13

Family

ID=40626932

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2008/010303 Ceased WO2009071301A2 (fr) 2007-12-04 2008-12-04 Procédé permettant de détecter des effecteurs de l'activité protéase de cis/trans isomérases

Country Status (2)

Country Link
CA (1) CA2708021A1 (fr)
WO (1) WO2009071301A2 (fr)

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002060436A2 (fr) * 2000-12-22 2002-08-08 Pintex Pharmaceuticals, Inc. Methodes d'inhibition de pathologies associees a pin1 a l'aide d'un compose de fredericamycine a

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002060436A2 (fr) * 2000-12-22 2002-08-08 Pintex Pharmaceuticals, Inc. Methodes d'inhibition de pathologies associees a pin1 a l'aide d'un compose de fredericamycine a

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
COAKER GITTA ET AL: "Eukaryotic cyclophilin as a molecular switch for effector activation", MOLECULAR MICROBIOLOGY, vol. 61, no. 6, September 2006 (2006-09-01), pages 1485 - 1496, XP002528760, ISSN: 0950-382X *
LYON WILLIAM R ET AL: "Trigger factor-mediated prolyl isomerization influences maturation of the Streptococcus pyogenes cysteine protease.", JOURNAL OF BACTERIOLOGY JUN 2003, vol. 185, no. 12, June 2003 (2003-06-01), pages 3661 - 3667, XP002528759, ISSN: 0021-9193 *
MCCORNACK M A ET AL: "HIV protease substrate conformation: modulation by cyclophilin A.", FEBS LETTERS 1 SEP 1997, vol. 414, no. 1, 1 September 1997 (1997-09-01), pages 84 - 88, XP002528758, ISSN: 0014-5793 *

Also Published As

Publication number Publication date
CA2708021A1 (fr) 2009-06-11
WO2009071301A2 (fr) 2009-06-11

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