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WO2009068749A3 - Apparatus and method for preparing sample analysis - Google Patents

Apparatus and method for preparing sample analysis Download PDF

Info

Publication number
WO2009068749A3
WO2009068749A3 PCT/FI2008/050691 FI2008050691W WO2009068749A3 WO 2009068749 A3 WO2009068749 A3 WO 2009068749A3 FI 2008050691 W FI2008050691 W FI 2008050691W WO 2009068749 A3 WO2009068749 A3 WO 2009068749A3
Authority
WO
WIPO (PCT)
Prior art keywords
sample
sample carrier
cutting
sample analysis
holder
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/FI2008/050691
Other languages
French (fr)
Other versions
WO2009068749A2 (en
Inventor
Vesa Erkkilae
Ari-Pekka Kitinoja
Jesse Mattila
Heimo Soitamo
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wallac Oy
Original Assignee
Wallac Oy
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wallac Oy filed Critical Wallac Oy
Publication of WO2009068749A2 publication Critical patent/WO2009068749A2/en
Publication of WO2009068749A3 publication Critical patent/WO2009068749A3/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/02—Devices for withdrawing samples
    • G01N1/04—Devices for withdrawing samples in the solid state, e.g. by cutting
    • G01N1/06—Devices for withdrawing samples in the solid state, e.g. by cutting providing a thin slice, e.g. microtome
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/2813—Producing thin layers of samples on a substrate, e.g. smearing, spinning-on
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/286—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q involving mechanical work, e.g. chopping, disintegrating, compacting, homogenising
    • G01N2001/2873—Cutting or cleaving
    • G01N2001/2886—Laser cutting, e.g. tissue catapult

Landscapes

  • Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Sampling And Sample Adjustment (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Abstract

Apparatus for handling sample carriers containing one or more biological samples impregnated therein. The apparatus comprises a holder (13) adapted to receive a sample carrier, and cutting tool (14) for cutting a sample-containing portion of the sample carrier supported by the holder. The cutting tool is adapted to direct to the sample carrier a localized cutting impact, such as laser beam or a water jet, which is moved on the surface of the sample carrier for detaching from the sample carrier said sample-containing portion. The invention offers a flexible, noiseless and dustless way of cutting samples for example for neonatal screening.
PCT/FI2008/050691 2007-11-30 2008-11-27 Apparatus and method for preparing sample analysis Ceased WO2009068749A2 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US99669207P 2007-11-30 2007-11-30
FI20075863 2007-11-30
FI20075863A FI20075863A0 (en) 2007-11-30 2007-11-30 Apparatus and method for preparing sample analysis
US60/996,692 2007-11-30

Publications (2)

Publication Number Publication Date
WO2009068749A2 WO2009068749A2 (en) 2009-06-04
WO2009068749A3 true WO2009068749A3 (en) 2009-07-16

Family

ID=38786792

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/FI2008/050691 Ceased WO2009068749A2 (en) 2007-11-30 2008-11-27 Apparatus and method for preparing sample analysis

Country Status (2)

Country Link
FI (1) FI20075863A0 (en)
WO (1) WO2009068749A2 (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106999955A (en) * 2014-07-29 2017-08-01 约阿希姆·格斯特尔 Components for preparing large quantities of samples for analytical methods
US11052484B2 (en) 2017-05-17 2021-07-06 Roche Molecular Systems, Inc. System for processing a dried fluid sample substrate and method therefor

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102011002193B4 (en) * 2011-04-20 2018-11-29 Leica Biosystems Nussloch Gmbh Tissue specimen handling device
DE102011002194B4 (en) 2011-04-20 2018-12-06 Leica Biosystems Nussloch Gmbh Tissue specimen handling device
WO2013044124A1 (en) * 2011-09-23 2013-03-28 Nanoink, Inc. Accurate quantitiation of biomarkers in samples
EP3567362B1 (en) 2018-05-09 2022-03-30 Euroimmun Medizinische Labordiagnostika AG Method and device for segmenting and separating flat distributed samples using laser cutting

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0583078A2 (en) * 1992-07-14 1994-02-16 Wallac Oy Method and apparatus for handling samples
DE19603996A1 (en) * 1996-02-05 1997-08-14 Bayer Ag Individual cells cut from polymer substrate foil
WO1998003628A1 (en) * 1996-07-19 1998-01-29 Bayer Aktiengesellschaft Device for separating micro objects
US20040077032A1 (en) * 2002-10-18 2004-04-22 Yung-Feng Nien Device and method for capturing biological tissues

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0583078A2 (en) * 1992-07-14 1994-02-16 Wallac Oy Method and apparatus for handling samples
DE19603996A1 (en) * 1996-02-05 1997-08-14 Bayer Ag Individual cells cut from polymer substrate foil
WO1998003628A1 (en) * 1996-07-19 1998-01-29 Bayer Aktiengesellschaft Device for separating micro objects
US20040077032A1 (en) * 2002-10-18 2004-04-22 Yung-Feng Nien Device and method for capturing biological tissues

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
SCHINDLER M: "A cut above the rest", THE BIOCHEMIST, 10-2002, pages 25 - 28, XP002485626, ISSN: 0954-982X, Retrieved from the Internet <URL:http://www.biochemist.org/bio/02405/0025/024050025.pdf> [retrieved on 20021001] *

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106999955A (en) * 2014-07-29 2017-08-01 约阿希姆·格斯特尔 Components for preparing large quantities of samples for analytical methods
US11052484B2 (en) 2017-05-17 2021-07-06 Roche Molecular Systems, Inc. System for processing a dried fluid sample substrate and method therefor

Also Published As

Publication number Publication date
FI20075863A0 (en) 2007-11-30
WO2009068749A2 (en) 2009-06-04

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