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WO2009063916A1 - 水系フィルムコーティング液、および、フィルムコーティング顆粒、ならびに、これを用いた錠剤 - Google Patents

水系フィルムコーティング液、および、フィルムコーティング顆粒、ならびに、これを用いた錠剤 Download PDF

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Publication number
WO2009063916A1
WO2009063916A1 PCT/JP2008/070609 JP2008070609W WO2009063916A1 WO 2009063916 A1 WO2009063916 A1 WO 2009063916A1 JP 2008070609 W JP2008070609 W JP 2008070609W WO 2009063916 A1 WO2009063916 A1 WO 2009063916A1
Authority
WO
WIPO (PCT)
Prior art keywords
film coating
coating solution
granule
aqueous film
aqueous
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/JP2008/070609
Other languages
English (en)
French (fr)
Inventor
Naoya Yoshida
Yoshihito Yaginuma
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Asahi Kasei Chemicals Corp
Original Assignee
Asahi Kasei Chemicals Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Asahi Kasei Chemicals Corp filed Critical Asahi Kasei Chemicals Corp
Priority to US12/742,853 priority Critical patent/US8268356B2/en
Priority to JP2009541160A priority patent/JP5524624B2/ja
Publication of WO2009063916A1 publication Critical patent/WO2009063916A1/ja
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A61K9/2806—Coating materials
    • A61K9/2833—Organic macromolecular compounds
    • A61K9/284—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone
    • A61K9/2846—Poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
    • A61K9/2081—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets with microcapsules or coated microparticles according to A61K9/50
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5026—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates

Landscapes

  • Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)

Abstract

　本発明は、耐酸性および徐放性に優れ、且つ、打錠に適した柔軟性を有し、生産性および経済性に優れる水系フィルムコーティング液等を提供することを目的とする。本発明の水系フィルムコーティング液は、アクリル酸エチル・メタクリル酸メチルコポリマー分散液と、メタクリル酸コポリマーＬＤと、可塑剤と、酸化チタンと、水とを含有し、これらアクリル酸エチル・メタクリル酸メチルコポリマー分散液、メタクリル酸コポリマーＬＤ、可塑剤および酸化チタンの固形分質量比が１００：４０～１００：５～５０：５～３０であり、且つ、固形分濃度が５～２０質量％である。
PCT/JP2008/070609 2007-11-16 2008-11-12 水系フィルムコーティング液、および、フィルムコーティング顆粒、ならびに、これを用いた錠剤 Ceased WO2009063916A1 (ja)

Priority Applications (2)

Application Number Priority Date Filing Date Title
US12/742,853 US8268356B2 (en) 2007-11-16 2008-11-12 Aqueous film coating solution, film coated granule and tablet using the same
JP2009541160A JP5524624B2 (ja) 2007-11-16 2008-11-12 水系フィルムコーティング液、および、フィルムコーティング顆粒、ならびに、これを用いた錠剤

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2007-297666 2007-11-16
JP2007297666 2007-11-16

Publications (1)

Publication Number Publication Date
WO2009063916A1 true WO2009063916A1 (ja) 2009-05-22

Family

ID=40638765

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/JP2008/070609 Ceased WO2009063916A1 (ja) 2007-11-16 2008-11-12 水系フィルムコーティング液、および、フィルムコーティング顆粒、ならびに、これを用いた錠剤

Country Status (3)

Country Link
US (1) US8268356B2 (ja)
JP (1) JP5524624B2 (ja)
WO (1) WO2009063916A1 (ja)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2009256344A (ja) * 2008-03-27 2009-11-05 Sawai Pharmaceutical Co Ltd プロトンポンプ阻害剤を含有する被覆微粒子
JP2023070979A (ja) * 2021-11-10 2023-05-22 トーアエイヨー株式会社 ベプリジルを含有する錠剤
WO2024111552A1 (ja) * 2022-11-21 2024-05-30 持田製薬株式会社 経口固形製剤

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2011043370A1 (ja) 2009-10-09 2011-04-14 旭化成ケミカルズ株式会社 コーティングフィルム、及びそれを用いた顆粒、錠剤
JP5890428B2 (ja) 2010-10-26 2016-03-22 キャプシュゲル・ベルジウム・エヌ・ヴィ バルク腸溶カプセルシェル
EP3446713A3 (en) 2012-05-02 2019-05-15 Capsugel Belgium NV Aqueous dispersions of controlled release polymers and shells and capsules thereof
EP3065720A1 (en) 2013-11-04 2016-09-14 Capsugel Belgium NV Methods and systems for improved bioavailability of active pharmaceutical ingredients including esomeprazole
CN110448532B (zh) * 2019-09-20 2021-08-10 无限极（中国）有限公司 一种灵芝多糖颗粒及其制备方法和应用
WO2021105041A1 (en) * 2019-11-27 2021-06-03 Dsm Ip Assets B.V. Mups tablet comprising riboflavin
EP4065088A1 (en) * 2019-11-27 2022-10-05 DSM IP Assets B.V. Multiple unit pellet system tablet comprising riboflavin

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH032115A (ja) * 1989-01-06 1991-01-08 Fh Holding & Co Ltd 持続放出性薬剤学的ペレット組成物
JP2000281564A (ja) * 1998-05-18 2000-10-10 Takeda Chem Ind Ltd 医薬製剤
WO2008081891A1 (ja) * 2006-12-28 2008-07-10 Takeda Pharmaceutical Company Limited 口腔内崩壊性固形製剤

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US4800087A (en) * 1986-11-24 1989-01-24 Mehta Atul M Taste-masked pharmaceutical compositions
US5196203A (en) * 1989-01-06 1993-03-23 F. H. Faulding & Co. Limited Theophylline dosage form
FR2655266B1 (fr) * 1989-12-05 1992-04-03 Smith Kline French Lab Compositions pharmaceutiques a base de cimetidine.
JPH04169522A (ja) 1990-11-01 1992-06-17 Shin Etsu Chem Co Ltd 徐放性錠剤およびその製造方法
JPH06293635A (ja) 1993-04-08 1994-10-21 Amano Pharmaceut Co Ltd 耐衝撃性腸溶性顆粒剤およびこれを含む錠剤
JPH072650A (ja) * 1993-06-18 1995-01-06 Tanabe Seiyaku Co Ltd 放出部位制御型製剤
JPH07330585A (ja) * 1994-06-01 1995-12-19 Nippon Roussel Kk 徐放性ジソピラミド製剤用造粒物及びその製造法
GB9416600D0 (en) * 1994-08-17 1994-10-12 Smithkline Beecham Plc Pharmaceutical formulation
JPH08109126A (ja) 1994-10-07 1996-04-30 Amano Pharmaceut Co Ltd 耐衝撃性腸溶性顆粒剤およびこれを含有する錠剤
JP3002115B2 (ja) 1995-06-01 2000-01-24 株式会社保健科学研究所 ヒト急性および慢性を含む持続性ストレス負荷における細胞内ＨＳＰ７０ｍＲＮＡの転写異常とその応用（新規ヒト細胞内ＳＨＳＰ７０ｍＲＮＡの転写発現とＨＳＰ７０ｍＲＮＡ転写異常との応用）
US20030091637A1 (en) * 2001-10-15 2003-05-15 Hans-Ulrich Petereit Use of a copolymer to prepare a pharmaceutical form that contains a peptide of protein as active principle
JP4169522B2 (ja) 2002-03-22 2008-10-22 株式会社リコー 画像処理装置、画像処理プログラム及びこのプログラムを記憶する記憶媒体
SE0201110D0 (sv) * 2002-04-12 2002-04-12 Astrazeneca Ab New film coating
CA2531019A1 (en) * 2003-06-30 2005-01-06 Takeda Pharmaceutical Company Limited Preventive/remedy for urinary disturbance
SI21637A (sl) * 2003-12-23 2005-06-30 LEK farmacevtska dru�ba d.d. Farmacevtska oblika z nadzorovanim sproščanjem
AU2005237360B2 (en) * 2004-04-30 2010-10-21 Astellas Pharma Inc. Time-limited release type granular pharmaceutical composition for oral administration and intraoral rapid disintegration tablet containing the composition
US8765187B2 (en) * 2007-07-17 2014-07-01 Asahi Kasei Chemicals Corporation Aqueous composition
US8367115B2 (en) * 2007-08-27 2013-02-05 Asahi Kasei Chemicals Corporation Process for production of crystalline cellulose and tablets containing granules

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH032115A (ja) * 1989-01-06 1991-01-08 Fh Holding & Co Ltd 持続放出性薬剤学的ペレット組成物
JP2000281564A (ja) * 1998-05-18 2000-10-10 Takeda Chem Ind Ltd 医薬製剤
WO2008081891A1 (ja) * 2006-12-28 2008-07-10 Takeda Pharmaceutical Company Limited 口腔内崩壊性固形製剤

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2009256344A (ja) * 2008-03-27 2009-11-05 Sawai Pharmaceutical Co Ltd プロトンポンプ阻害剤を含有する被覆微粒子
JP2023070979A (ja) * 2021-11-10 2023-05-22 トーアエイヨー株式会社 ベプリジルを含有する錠剤
WO2024111552A1 (ja) * 2022-11-21 2024-05-30 持田製薬株式会社 経口固形製剤

Also Published As

Publication number Publication date
US20100260839A1 (en) 2010-10-14
JPWO2009063916A1 (ja) 2011-03-31
JP5524624B2 (ja) 2014-06-18
US8268356B2 (en) 2012-09-18

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