[go: up one dir, main page]

WO2009053742A3 - Salts of nefopam and their use in therapy - Google Patents

Salts of nefopam and their use in therapy Download PDF

Info

Publication number
WO2009053742A3
WO2009053742A3 PCT/GB2008/050979 GB2008050979W WO2009053742A3 WO 2009053742 A3 WO2009053742 A3 WO 2009053742A3 GB 2008050979 W GB2008050979 W GB 2008050979W WO 2009053742 A3 WO2009053742 A3 WO 2009053742A3
Authority
WO
WIPO (PCT)
Prior art keywords
nefopam
therapy
salts
relates
novel salts
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/GB2008/050979
Other languages
French (fr)
Other versions
WO2009053742A2 (en
Inventor
Peter Tiffin
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sosei R&D Ltd
Original Assignee
Arakis Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Arakis Ltd filed Critical Arakis Ltd
Publication of WO2009053742A2 publication Critical patent/WO2009053742A2/en
Publication of WO2009053742A3 publication Critical patent/WO2009053742A3/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D267/00—Heterocyclic compounds containing rings of more than six members having one nitrogen atom and one oxygen atom as the only ring hetero atoms
    • C07D267/22—Eight-membered rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

This invention relates to novel salts of Nefopam, which may be suitable for use in therapy.
PCT/GB2008/050979 2007-10-25 2008-10-23 Salts of nefopam and their use in therapy Ceased WO2009053742A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0721013.1A GB0721013D0 (en) 2007-10-25 2007-10-25 New Salts
GB0721013.1 2007-10-25

Publications (2)

Publication Number Publication Date
WO2009053742A2 WO2009053742A2 (en) 2009-04-30
WO2009053742A3 true WO2009053742A3 (en) 2009-07-23

Family

ID=38829977

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/GB2008/050979 Ceased WO2009053742A2 (en) 2007-10-25 2008-10-23 Salts of nefopam and their use in therapy

Country Status (2)

Country Link
GB (1) GB0721013D0 (en)
WO (1) WO2009053742A2 (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2940911B1 (en) * 2009-01-13 2012-09-21 Philippe Perovitch FORMULATION FOR ORAL TRANSMUCOSAL ADMINISTRATION OF ANTALGIC AND / OR ANTI-SPASMODIC MOLECULES
CN105687185B (en) * 2009-12-15 2019-07-09 儿童医院 The method of the disease of invasion fiber type tumor disease and beta-catenin mediation is treated using nefopam compound
US10736905B1 (en) 2016-09-09 2020-08-11 Shahin Fatholahi Nefopam dosage forms and methods of treatment
US11446311B2 (en) 2017-09-08 2022-09-20 Shahin Fatholahi Methods for treating pain associated with sickle cell disease
US10736874B1 (en) 2017-09-08 2020-08-11 Shahin Fatholahi Methods for treating pain associated with sickle cell disease

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003105833A1 (en) * 2002-06-17 2003-12-24 Arakis Ltd. Formulation of nefopam and its use in the treatment of pain
WO2005056539A2 (en) * 2003-12-12 2005-06-23 Arakis Ltd. A process for the resolution of nefopam

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003105833A1 (en) * 2002-06-17 2003-12-24 Arakis Ltd. Formulation of nefopam and its use in the treatment of pain
WO2005056539A2 (en) * 2003-12-12 2005-06-23 Arakis Ltd. A process for the resolution of nefopam

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
BOLT, A. G. ET AL: "Stereoselective demethylation of the enantiomers of nefopam, an experimental antidepressant and skeletal muscle relaxant", XENOBIOTICA , 4(6), 355-63 CODEN: XENOBH; ISSN: 0049-8254, 1974, XP002525368 *

Also Published As

Publication number Publication date
GB0721013D0 (en) 2007-12-05
WO2009053742A2 (en) 2009-04-30

Similar Documents

Publication Publication Date Title
BRPI1007477A2 (en) Method and well treatment composition
WO2010083385A3 (en) Compounds for reducing drug resistance and uses thereof
WO2012088290A3 (en) Tri-variable domain binding proteins and uses thereof
LT3205334T (en) METHOD AND COMPOSITION FOR THE TREATMENT OF EYE HYPERTENSION AND PROMOTION
IL208027A0 (en) Methods, compositions, and kits for treating pain and pruritus
WO2009089494A3 (en) Pharmaceutical compositions
BRPI0814941A2 (en) COMPOSITION OF SEED TREATMENT, AND, SEED TREATMENT METHOD.
IL219107A0 (en) 2-amino--5,5-difluoro-5,6-dihydro-4h-oxazines as bace 1 and/or bace 2 inhibitors
ZA201103584B (en) Whey protein compositions,methods and uses
WO2009108730A3 (en) Forms of rifaximin and uses thereof
IL194865A0 (en) Haloaryl substituted aminopurines, compositions thereof, and methods of treatment therewith
WO2009129246A3 (en) Compositions and methods for preparing and using same
IL207164A0 (en) Folates, compositions and uses thereof
PL3050571T3 (en) Digestive enzyme preparation for the treatment of eclampsia
WO2009150255A3 (en) Markers for predicting response and survival in anti-egfr treated patients
IL207792A0 (en) Methods, dosage forms, and kits for administering ziprasidone without food
EP2340297A4 (en) Composition, method of making the same, and use thereof
AU2008263581A8 (en) Well treatment
BRPI0822129A2 (en) Aldh-2c inhibitors in the treatment of addiction.
WO2009053742A3 (en) Salts of nefopam and their use in therapy
WO2010017466A3 (en) Phenobarbital salts; methods of making; and methods of use thereof
IL195096A0 (en) Aqueous tobacco leaf extract, uses thereof in the treatment of dependence
BRPI0909302A2 (en) reduction of conjugation plasmids in bacteria
AU2009309277A8 (en) Efficient expression of truncated human RNASET2 in E. Coli
WO2010120400A3 (en) Substituted 4-amino-5-benzoyl-2-(phenylamino)thiophene-3-carbonitriles and substituted 4-amino-5-benzoyl-2-(phenylamino)thiophene-3-carboxamides as tubulin polymerization inhibitors

Legal Events

Date Code Title Description
NENP Non-entry into the national phase

Ref country code: DE

122 Ep: pct application non-entry in european phase

Ref document number: 08806786

Country of ref document: EP

Kind code of ref document: A2